The Major Discoveries Of Cajal And His Disciples Consolidated Milestones For The Neuroscience Of The Xxist Century
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The Major Discoveries Of Cajal And His Disciples Consolidated Milestones For The Neuroscience Of The Xxist Century
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Author : Fernando de Castro
language : en
Publisher: Frontiers Media SA
Release Date : 2017-04-25
The Major Discoveries Of Cajal And His Disciples Consolidated Milestones For The Neuroscience Of The Xxist Century written by Fernando de Castro and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-04-25 with Electronic book categories.
When Santiago Ramón y Cajal started to unravel the fine structure of the nervous system in the last decades of the XIXth century maybe only his unbeatable soul of brave Spaniard imagined that most of the descriptions were scientific truths that lasted to date. Simple histological stainings, curiosity to ameliorate these, monocular microscopes, patience for drawing his observations and a rich imaginative open mind: this is the recipy for Cajal success. His descriptions of connectivity in the nervous system, compiled in Cajal's opus magna published in 1904 ("Textura del sistema nervioso del hombre y los vertebrados") and 1911 ("Histologie du systeme nerveux"), have been corroborated by modern techniques decade after decade. Even more, the main hypothesis that Cajal raised are universally recognised as biological laws, today: the neuron theory, the law on the dynamic polarization of the neuron and the chemotropic hypothesis. That is: the nervous system is not a sincitial network but is formed by individual cells; the transmission of the nerve impulses follow a main direction within a given neuron; the axons are guided by chemical substances in a chemotropic way, till form synapses with their targets. Attracted by Cajal's strong personality and scientific success, a number of medical students and doctors join him in the crusade to explore the nervous system. And the seed planted by the universal savant was really successful: Francisco Tello described interesting aspects of the regeneration of peripheral nerves which are very useful for neuroscientist currently working in this topic; Nicolás Achúcarro significantly contributed to study neuroglia and future microglia; Pío del Río-Hortega identified two out of the four main nervous cell types, the oligodendrocytes and microglia, and proposed an almost still valid classification for the CNS tumours; Fernando de Castro made was the first description of arterial chemoreceptors in the carotid body; Rafael Lorente de Nó was a dominant figure of Neuroscience for decades after the IInd World War, first describing the columnar organization of the cerebral cortex well before Mountcastle, Hubbel and Wiesel. Even less recognised co-workers and disciples of Cajal (his brother Pedro Ramón y Cajal, Domingo Sánchez, the neurologist Rodríguez-Lafora... protagonised discoveries that are consolidated scientific truths today). Altogether, it is difficult (if not impossible) to find a school in biology contributing in such a fundamental and variated way to the common acervo like the collectively known as Cajal School or Spanish Neurological School. Although the particular way to work of the Maestro, selecting a pleiade of brilliant collaborators with whom accomplish such a titanic feat, giving them freedom for their studies, has been recognised and confronted to antagonic systems followed by other relevant scientists and scientific schools, the general recognition of such a significant major milestones for Neuroscience and their vigency in the well-marched XXIst century is not: this is the purpose of this Ebook, to remind all these examples of how successful can be the scientific work when it is minutious, constant and performed by brilliant, imaginative and skilled scientists with a minimal conditions supporting their efforts.
The Major Discoveries Of Cajal And His Disciples Consolidated Milestones For The Neuroscience Of The Xxist Century
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Author :
language : en
Publisher:
Release Date : 2017
The Major Discoveries Of Cajal And His Disciples Consolidated Milestones For The Neuroscience Of The Xxist Century written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017 with categories.
When Santiago Ramón y Cajal started to unravel the fine structure of the nervous system in the last decades of the XIXth century maybe only his unbeatable soul of brave Spaniard imagined that most of the descriptions were scientific truths that lasted to date. Simple histological stainings, curiosity to ameliorate these, monocular microscopes, patience for drawing his observations and a rich imaginative open mind: this is the recipy for Cajal success. His descriptions of connectivity in the nervous system, compiled in Cajal's opus magna published in 1904 ("Textura del sistema nervioso del hombre y los vertebrados") and 1911 ("Histologie du systeme nerveux"), have been corroborated by modern techniques decade after decade. Even more, the main hypothesis that Cajal raised are universally recognised as biological laws, today: the neuron theory, the law on the dynamic polarization of the neuron and the chemotropic hypothesis. That is: the nervous system is not a sincitial network but is formed by individual cells; the transmission of the nerve impulses follow a main direction within a given neuron; the axons are guided by chemical substances in a chemotropic way, till form synapses with their targets. Attracted by Cajal's strong personality and scientific success, a number of medical students and doctors join him in the crusade to explore the nervous system. And the seed planted by the universal savant was really successful: Francisco Tello described interesting aspects of the regeneration of peripheral nerves which are very useful for neuroscientist currently working in this topic; Nicolás Achúcarro significantly contributed to study neuroglia and future microglia; Pío del Río-Hortega identified two out of the four main nervous cell types, the oligodendrocytes and microglia, and proposed an almost still valid classification for the CNS tumours; Fernando de Castro made was the first description of arterial chemoreceptors in the carotid body; Rafael Lorente de Nó was a dominant figure of Neuroscience for decades after the IInd World War, first describing the columnar organization of the cerebral cortex well before Mountcastle, Hubbel and Wiesel. Even less recognised co-workers and disciples of Cajal (his brother Pedro Ramón y Cajal, Domingo Sánchez, the neurologist Rodríguez-Lafora... protagonised discoveries that are consolidated scientific truths today). Altogether, it is difficult (if not impossible) to find a school in biology contributing in such a fundamental and variated way to the common acervo like the collectively known as Cajal School or Spanish Neurological School. Although the particular way to work of the Maestro, selecting a pleiade of brilliant collaborators with whom accomplish such a titanic feat, giving them freedom for their studies, has been recognised and confronted to antagonic systems followed by other relevant scientists and scientific schools, the general recognition of such a significant major milestones for Neuroscience and their vigency in the well-marched XXIst century is not: this is the purpose of this Ebook, to remind all these examples of how successful can be the scientific work when it is minutious, constant and performed by brilliant, imaginative and skilled scientists with a minimal conditions supporting their efforts.When Santiago Ramón y Cajal started to unravel the fine structure of the nervous system in the last decades of the XIXth century maybe only his unbeatable soul of brave Spaniard imagined that most of the descriptions were scientific truths that lasted to date. Simple histological stainings, curiosity to ameliorate these, monocular microscopes, patience for drawing his observations and a rich imaginative open mind: this is the recipy for Cajal success. His descriptions of connectivity in the nervous system, compiled in Cajal's opus magna published in 1904 ("Textura del sistema nervioso del hombre y los vertebrados") and 1911 ("Histologie du systeme nerveux"), have been corroborated by modern techniques decade after decade. Even more, the main hypothesis that Cajal raised are universally recognised as biological laws, today: the neuron theory, the law on the dynamic polarization of the neuron and the chemotropic hypothesis. That is: the nervous system is not a sincitial network but is formed by individual cells; the transmission of the nerve impulses follow a main direction within a given neuron; the axons are guided by chemical substances in a chemotropic way, till form synapses with their targets. Attracted by Cajal's strong personality and scientific success, a number of medical students and doctors join him in the crusade to explore the nervous system. And the seed planted by the universal savant was really successful: Francisco Tello described interesting aspects of the regeneration of peripheral nerves which are very useful for neuroscientist currently working in this topic; Nicolás Achúcarro significantly contributed to study neuroglia and future microglia; Pío del Río-Hortega identified two out of the four main nervous cell types, the oligodendrocytes and microglia, and proposed an almost still valid classification for the CNS tumours; Fernando de Castro made was the first description of arterial chemoreceptors in the carotid body; Rafael Lorente de Nó was a dominant figure of Neuroscience for decades after the IInd World War, first describing the columnar organization of the cerebral cortex well before Mountcastle, Hubbel and Wiesel. Even less recognised co-workers and disciples of Cajal (his brother Pedro Ramón y Cajal, Domingo Sánchez, the neurologist Rodríguez-Lafora... protagonised discoveries that are consolidated scientific truths today). Altogether, it is difficult (if not impossible) to find a school in biology contributing in such a fundamental and variated way to the common acervo like the collectively known as Cajal School or Spanish Neurological School. Although the particular way to work of the Maestro, selecting a pleiade of brilliant collaborators with whom accomplish such a titanic feat, giving them freedom for their studies, has been recognised and confronted to antagonic systems followed by other relevant scientists and scientific schools, the general recognition of such a significant major milestones for Neuroscience and their vigency in the well-marched XXIst century is not: this is the purpose of this Ebook, to remind all these examples of how successful can be the scientific work when it is minutious, constant and performed by brilliant, imaginative and skilled scientists with a minimal conditions supporting their efforts.
Neural Networks
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Author : Ranjodh Singh Dhaliwal
language : en
Publisher: U of Minnesota Press
Release Date : 2024-04-09
Neural Networks written by Ranjodh Singh Dhaliwal and has been published by U of Minnesota Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-04-09 with Social Science categories.
A critical examination of the figure of the neural network as it mediates neuroscientific and computational discourses and technical practices Neural Networks proposes to reconstruct situated practices, social histories, mediating techniques, and ontological assumptions that inform the computational project of the same name. If so-called machine learning comprises a statistical approach to pattern extraction, then neural networks can be defined as a biologically inspired model that relies on probabilistically weighted neuron-like units to identify such patterns. Far from signaling the ultimate convergence of human and machine intelligence, however, neural networks highlight the technologization of neurophysiology that characterizes virtually all strands of neuroscientific and AI research of the past century. Taking this traffic as its starting point, this volume explores how cognition came to be constructed as essentially computational in nature, to the point of underwriting a technologized view of human biology, psychology, and sociability, and how countermovements provide resources for thinking otherwise.
Santiago Ram N Y Cajal El Hombre El Cient Fico El Intelectual
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Author : Alberto Jiménez Schuhmacher
language : es
Publisher: Prensas de la Universidad de Zaragoza
Release Date : 2023-04-18
Santiago Ram N Y Cajal El Hombre El Cient Fico El Intelectual written by Alberto Jiménez Schuhmacher and has been published by Prensas de la Universidad de Zaragoza this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-04-18 with Biography & Autobiography categories.
Santiago Ramón y Cajal. El hombre, el científico, el intelectual es el homenaje de la Universidad de Zaragoza a su premio nobel, para conmemorar el Trienio Cajal, designado por el Ministerio de Ciencia e Innovación entre 2022 y 2024. En el otoño de 1869, Santiago Ramón y Cajal se matricula en la Universidad de Zaragoza en el curso preparatorio para poder comenzar al año siguiente los estudios de Medicina. Cumplía de este modo el deseo y la férrea voluntad de su padre, don Justo, figura esencial en la forja de nuestro único Premio Nobel en ciencias en España. La Universidad de Zaragoza, su venerada alma mater, hace un recorrido en torno a la vida del sabio aragonés, desgranando cada una de sus facetas como hombre, científico e intelectual, culminando de este modo la obra hasta el momento más completa que sobre su figura se ha editado.
The Brain In Search Of Itself
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Author : Benjamin Ehrlich
language : en
Publisher: Farrar, Straus and Giroux
Release Date : 2022-03-15
The Brain In Search Of Itself written by Benjamin Ehrlich and has been published by Farrar, Straus and Giroux this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-15 with Biography & Autobiography categories.
"Passionate and meticulous . . . [Ehrlich] delivers thought-provoking metaphors, unforgettable scenes and many beautifully worded phrases." —Benjamin Labatut, The New York Times Book Review One of The Telegraph's best books of the year The first major biography of the Nobel Prize–winning scientist who discovered neurons and transformed our understanding of the human mind—illustrated with his extraordinary anatomical drawings Unless you’re a neuroscientist, Santiago Ramón y Cajal is likely the most important figure in the history of biology you’ve never heard of. Along with Charles Darwin and Louis Pasteur, he ranks among the most brilliant and original biologists of the nineteenth century, and his discoveries have done for our understanding of the human brain what the work of Galileo and Sir Isaac Newton did for our conception of the physical universe. He was awarded the Nobel Prize in 1906 for his lifelong investigation of the structure of neurons: “The mysterious butterflies of the soul,” Cajal called them, “whose beating of wings may one day reveal to us the secrets of the mind.” And he produced a dazzling oeuvre of anatomical drawings, whose alien beauty grace the pages of medical textbooks and the walls of museums to this day. Benjamin Ehrlich’s The Brain in Search of Itself is the first major biography in English of this singular figure, whose scientific odyssey mirrored the rocky journey of his beloved homeland of Spain into the twentieth century. Born into relative poverty in a mountaintop hamlet, Cajal was an enterprising and unruly child whose ambitions were both nurtured and thwarted by his father, a country doctor with a flinty disposition. A portrait of a nation as well a biography, The Brain in Search of Itself follows Cajal from the hinterlands to Barcelona and Madrid, where he became an illustrious figure—resisting and ultimately transforming the rigid hierarchies and underdeveloped science that surrounded him. To momentous effect, Cajal devised a theory that was as controversial in his own time as it is universal in ours: that the nervous system is comprised of individual cells with distinctive roles, just like any other organ in the body. In one of the greatest scientific rivalries in history, he argued his case against Camillo Golgi and prevailed. In our age of neuro-imaging and investigations into the neural basis of the mind, Cajal is the artistic and scientific forefather we must get to know. The Brain in Search of Itself is at once the story of how the brain as we know it came into being and a finely wrought portrait of an individual as fantastical and complex as the subject to which he devoted his life.
Texture Of The Nervous System Of Man And The Vertebrates
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Author : Santiago R.y Cajal
language : en
Publisher: Springer Science & Business Media
Release Date : 2002-10-14
Texture Of The Nervous System Of Man And The Vertebrates written by Santiago R.y Cajal and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-10-14 with Medical categories.
The works and thoughts of Santiago Ramn y Cajal in a faithful rendition of the original Spanish version, with additional facts contained in the French translation, both of which are currently quoted around 200 times each year in the scientific literature. This is the only authorized English translation and makes use of uniform nomenclature according to contemporary scientific English. Most of the illustrations are reproductions of Cajal's original art work, with cross references to the figure numbers of the Spanish and French versions, while the taxonomic glossary uses current scientific names, and their colloquial English counterparts.
The Arterial Chemoreceptors
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Author : Yoshiaki Hayashida
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-04-24
The Arterial Chemoreceptors written by Yoshiaki Hayashida and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-04-24 with Medical categories.
This book represents an updated review of the physiology of the carotid body chemoreceptors. It contains results in the topics at the frontiers of future developments in O2-sensing in chemoreceptor cells. Additionally, this volume provides data from studies carried out in other O2-sensing tissues including pulmonary vasculature and erythropoietin producing cells. It is a prime source of information and a guideline for arterial chemoreception researchers.
Recollections Of My Life
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Author : Santiago Ramon Y Cajal
language : en
Publisher: MIT Press
Release Date : 1989-07-06
Recollections Of My Life written by Santiago Ramon Y Cajal and has been published by MIT Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989-07-06 with Medical categories.
Santiago Ramón y Cajal (1852-1934) made prolific and lasting contributions to understanding "the life of the infinitely small." Santiago Ramón y Cajal (1852-1934) made prolific and lasting contributions to understanding "the life of the infinitely small." Widely thought of as the founder of neuroscience, Cajal made remarkable explorations into the organization and function of the nervous system. His work is still referred to more than that of any other scientist in the field.W. Maxwell Cowan's foreword to this edition conveys the excitement and energy of Cajal's life and endeavors, the liveliness and flamboyance of his engagements with the microscope. Cowan surveys Cajal's salient discoveries, noting that almost every important conceptual issue in neurobiology was foreshadowed in Cajal's work: the initial description of the climbing fibers of the cerebellum, the discovery of the growth cone, the concept of the "dynamic polarity" of the neurom an anticipation of the later discovery of axonal transport, and the prediction that new synapses may be formed throughout life to serve as a physical basis for learning and memory. W. Maxwell Cowen is Vice President and Chief Scientific Officer at the Howard Hughes Medical Institute.
Cajal S Neuronal Forest
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Author : Javier DeFelipe
language : en
Publisher: Oxford University Press
Release Date : 2018
Cajal S Neuronal Forest written by Javier DeFelipe and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018 with Medical categories.
Cajal's Neuronal Forest: Science and Art continues the tradition set forth by its sister volume Cajal's Butterflies of the Soul (OUP, 2009). This new collection contains hundreds of beautiful rarely-seen-before figures produced throughout the nineteenth century and the beginning of the twentieth century by famed father-of-modern-neuroscience Santiago Ram n y Cajal (1852-1934) and his contemporaries. Cajal was captivated by the beautiful shapes of the cells of the nervous system. He and his fellow scientists saw neurons as trees and glial cells as bushes. Given their high density and arrangement, neurons and glial resembled a thick forest, a seemingly impenetrable terrain of interacting cells mediating cognition and behavior. In unraveling the mysteries of the brain, these researchers encountered an almost infinite number of cellular forms with an extraordinary beauty, which they could not help but put pen to paper, allowing them to discover a new artistic world- the neuronal forest- that gave free rein not only to their imagination, but to a new way of viewing the brain as well. This book has been divided into two parts. The first focuses on the scientific atmosphere in Cajal's times, on the history of the neuron, and the anatomical challenge posed in studying neuronal connections. It also delves into the artistic skills of Cajal and other important pioneers in neuroscience and how the neuronal forests have served as an unlimited source of artistic inspiration. The second consists of 275 original drawings by Cajal. All were published over the course of his scientific career and cover virtually all of his research fields of interest, including the spinal cord, the optic lobe and retina, cerebral cortex, and many other regions of the brain. Cajal's Neuronal Forest: Science and Art is a testament to the natural beauty found in science. Despite the common misconception that the drawings of Cajal and other scientists of the time are pieces of art, these drawings are in fact copies of histological preparations and contributed greatly to the discoveries made in the field of neuroscience. This book is a gem in any library, whether serving as a medical history or a gallery of stunning sketches.
Recollections Of My Life
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Author : Santiago Ramón y Cajal
language : en
Publisher:
Release Date : 1966
Recollections Of My Life written by Santiago Ramón y Cajal and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1966 with Anatomists categories.
Santiago Ramon y Cajal (1852-1934) made prolific and lasting contributions to understanding "the life of the infinitely small." Widely thought of as the founder of neuroscience, Cajal made remarkable explorations into the organization and function of the nervous system. His work is still referred to more than that of any other scientist in the field.W. Maxwell Cowan's foreword to this edition conveys the excitement and energy of Cajal's life and endeavors, the liveliness and flamboyance of his engagements with the microscope. Cowan surveys Cajal's salient discoveries, noting that almost every important conceptual issue in neurobiology was foreshadowed in Cajal's work: the initial description of the climbing fibers of the cerebellum, the discovery of the growth cone, the concept of the "dynamic polarity" of the neurom an anticipation of the later discovery of axonal transport, and the prediction that new synapses may be formed throughout life to serve as a physical basis for learning and memory.W. Maxwell Cowen is Vice President and Chief Scientific Officer at the Howard Hughes Medical Institute."