The Mathematical Modeling Of Metabolic And Endocrine Systems

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The Mathematical Modeling Of Metabolic And Endocrine Systems
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Author : Ewart R. Carson
language : en
Publisher:
Release Date : 1983-02-25
The Mathematical Modeling Of Metabolic And Endocrine Systems written by Ewart R. Carson and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1983-02-25 with Medical categories.
A Wiley-Interscience publication.
The Mathematical Modeling Of Metabolic And Endocrine Systems
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Author : Ewart R. Carson
language : en
Publisher:
Release Date :
The Mathematical Modeling Of Metabolic And Endocrine Systems written by Ewart R. Carson and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.
The Mathematical Modeling Of Metabolic And Endocrine Systems
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Author : Ewart R. Carson
language : en
Publisher:
Release Date : 1983-02-25
The Mathematical Modeling Of Metabolic And Endocrine Systems written by Ewart R. Carson and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1983-02-25 with Medical categories.
Introduces the concepts, methods and techniques of model formulation, identification, and validation as applicable to metabolic and endocrine processes. Shows how modeling can be used to provide a concise description of complex dynamic processes, to test hypotheses concerning physiological and biochemical structure, and to estimate physiological quantities (parameters) that otherwise would not be directly accessible to measurement. Includes numerous examples and case studies.
Mathematical Modeling In Experimental Nutrition
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Author : Andrew J. Clifford
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-21
Mathematical Modeling In Experimental Nutrition written by Andrew J. Clifford and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-21 with Medical categories.
Nutrients have been recognized as essential for maximum growth, successful reproduction, and infection prevention since the 1940s; since that time, the lion's share of nutrient research has focused on defining their role in these processes. Around 1990, however, a major shift began in the way that researchers viewed some nutrients particularly the vitamins. This shift was motivated by the discovery that modest declines in vitamin nutritional status are associated with an increased risk of ill-health and disease (such as neural tube defects, heart disease, and cancer), especially in those populations or individuals who are genetically predisposed. In an effort to expand upon this new understanding of nutrient action, nutritionists are increasingly turning their focus to the mathematical modeling of nutrient kinetic data. The availability of suitably-tagged (isotope) nutrients (such as B-carotene, vitamin A, folate, among others), sensitive analytical methods to trace them in humans (mass spectrometry and accelerator mass spectrometry), and powerful software (capable of solving and manipulating differential equations efficiently and accurately), has allowed researchers to construct mathematical models aimed at characterizing the dynamic and kinetic behavior of key nutrients in vivo in humans at an unparalleled level of detail.
Dynamic Systems Biology Modeling And Simulation
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Author : Joseph DiStefano III
language : en
Publisher: Academic Press
Release Date : 2015-01-10
Dynamic Systems Biology Modeling And Simulation written by Joseph DiStefano III and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-01-10 with Science categories.
Dynamic Systems Biology Modeling and Simuation consolidates and unifies classical and contemporary multiscale methodologies for mathematical modeling and computer simulation of dynamic biological systems – from molecular/cellular, organ-system, on up to population levels. The book pedagogy is developed as a well-annotated, systematic tutorial – with clearly spelled-out and unified nomenclature – derived from the author's own modeling efforts, publications and teaching over half a century. Ambiguities in some concepts and tools are clarified and others are rendered more accessible and practical. The latter include novel qualitative theory and methodologies for recognizing dynamical signatures in data using structural (multicompartmental and network) models and graph theory; and analyzing structural and measurement (data) models for quantification feasibility. The level is basic-to-intermediate, with much emphasis on biomodeling from real biodata, for use in real applications. - Introductory coverage of core mathematical concepts such as linear and nonlinear differential and difference equations, Laplace transforms, linear algebra, probability, statistics and stochastics topics - The pertinent biology, biochemistry, biophysics or pharmacology for modeling are provided, to support understanding the amalgam of "math modeling with life sciences - Strong emphasis on quantifying as well as building and analyzing biomodels: includes methodology and computational tools for parameter identifiability and sensitivity analysis; parameter estimation from real data; model distinguishability and simplification; and practical bioexperiment design and optimization - Companion website provides solutions and program code for examples and exercises using Matlab, Simulink, VisSim, SimBiology, SAAMII, AMIGO, Copasi and SBML-coded models - A full set of PowerPoint slides are available from the author for teaching from his textbook. He uses them to teach a 10 week quarter upper division course at UCLA, which meets twice a week, so there are 20 lectures. They can easily be augmented or stretched for a 15 week semester course - Importantly, the slides are editable, so they can be readily adapted to a lecturer's personal style and course content needs. The lectures are based on excerpts from 12 of the first 13 chapters of DSBMS. They are designed to highlight the key course material, as a study guide and structure for students following the full text content - The complete PowerPoint slide package (~25 MB) can be obtained by instructors (or prospective instructors) by emailing the author directly, at: [email protected]
Modeling Ruminant Digestion And Metabolism
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Author : R.L. Baldwin
language : en
Publisher: Springer Science & Business Media
Release Date : 1995-05-31
Modeling Ruminant Digestion And Metabolism written by R.L. Baldwin and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-05-31 with Medical categories.
Role of mminants in human food production; Whyan animal scientist would choose to model animal systems; Basic organization of this book; Modeling principIes and terminology; Classification of models; Objectives in modeling; The modeling process I objective statements, block diagrams, equation forms and parameterization; Steps in modeling; Setting the modeling objective; Block diagrams; Formulation of mathematical statements; Development of numerical inputs; The modeling process II - solution algorithms, model evaluations and parameter estimation; Model solution algorithms; Evaluation of management and research models; Evaluation and use of analytical models for parameter estimation; Decision support software; Animal energetic models; Thermodynamic concepts in nutrition; Historical development of bases for feeding system models; Energy requirements for maintenance and production; Equations used to estimate maintenance and costs of production; Components of maintenanace; Protein and amino acid models; Current protein and amino acid systems; Analytic models of amino aicd and protein metabolism; Dynamic modeling; Biology and algebraic models of ruminant digestion; The rumen microbes and their metabolism; Balance models of ruminant digestion; An analytical model of rumen digestion; Microbial growth elements; Biology and algebraic models of growth; Classical equations for growth; Nutritional models of growth; Concepts of lhe basic biology of growth used in mechanistic models; Biology of lactation; Decent evolution of feeding systems for lactating dairy cattle; An analytical model of nutrient transactions during lactation; Dynamic models of ruminant digestion; Early dynamic models; Current dynamic models; Dynamic models of ruminant adipose tissue metabolism; Evolution of steady-state balance model; Radioisotope tracer elemets; Dynamic models of ruminant mammary metabolism; Development of model inputs and initial parameters; Descriptions of a model of mammary gland metabolism; Dynamic models of liver and viscera metabolism; Overall structure and notation; Mechanistic, dynamic models of growth; Beef growth models; Sheep growth and metabolism model; Lactation Background on MOLL Y. CSL; The program MOLL Y. CSL; Evaluation and use of a growth and lactation model; Behavioral analyses; Sensitivity analyses; Bioeconomic analyse.
Mathematics In Biology And Medicine
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Author : Vincenzo Capasso
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-13
Mathematics In Biology And Medicine written by Vincenzo Capasso and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-13 with Mathematics categories.
Endogenous And Exogenous Regulation And Control Of Physiological Systems
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Author : Robert B. Northrop
language : en
Publisher: CRC Press
Release Date : 2020-11-26
Endogenous And Exogenous Regulation And Control Of Physiological Systems written by Robert B. Northrop and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-26 with Medical categories.
From a biomedical engineering perspective, this book takes an analytic, quantitative approach to describing the basic components of physiological regulators and control systems (PRCs). In Endogenous and Exogenous Regulation and Control of Physiological Systems, the author provides grounding in the classical methods of designing linear and nonlinear systems. He also offers state-of-the-art material on the potential of PRCs to treat immune system ailments, most notably AIDS and cancer. The book focuses on certain "wet" physiological regulators, such as those using endocrine hormones as parametric control substances. Endogenous and Exogenous Regulation and Control of Physiological Systems includes simulations that illustrate model validations and the putative control of cancer and HIV proliferation. It explores novel, untried immunotherapies on the cutting-edge of PRC treatment and explores the latest technologies.
Mathematical Analysis For Modeling
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Author : Judah Rosenblatt
language : en
Publisher: CRC Press
Release Date : 1998-12-28
Mathematical Analysis For Modeling written by Judah Rosenblatt and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998-12-28 with Mathematics categories.
Mathematical Analysis for Modeling is intended for those who want to understand the substance of mathematics, rather than just having familiarity with its techniques. It provides a thorough understanding of how mathematics is developed for and applies to solving scientific and engineering problems. The authors stress the construction of mathematical descriptions of scientific and engineering situations, rather than rote memorizations of proofs and formulas. Emphasis is placed on algorithms as solutions to problems and on insight rather than formal derivations.
Modelling Methodology For Physiology And Medicine
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Author : Ewart Carson
language : en
Publisher: Elsevier
Release Date : 2000-12-31
Modelling Methodology For Physiology And Medicine written by Ewart Carson and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-12-31 with Mathematics categories.
Modelling Methodology for Physiology and Medicine offers a unique approach and an unprecedented range of coverage of the state-of-the-art, advanced modelling methodology that is widely applicable to physiology and medicine. The book opens with a clear and integrated treatment of advanced methodology for developing mathematical models of physiology and medical systems. Readers are then shown how to apply this methodology beneficially to real-world problems in physiology and medicine, such as circulation and respiration. - Builds upon and enhances the readers existing knowledge of modelling methodology and practice - Editors are internationally renowned leaders in their respective fields