The Molecular Biology Of Poliovirus
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The Molecular Biology Of Poliovirus
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Author : F. Koch
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
The Molecular Biology Of Poliovirus written by F. Koch and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
Years ago when we were asked to write a book on the present-day knowledge of the molecular biology of poliovirus, we did not expect that such an apparently simple task could involve so much time and effort. Our writing was hampered by the fact that both of us are full time "workers", so that this monograph is mainly a spare time expedience. The main attention of this book focuses on a detailed review of the molecular biology of poliovirus and especially on the advances of the last decade; medical and environmental aspects are only briefly mentioned. Observations from older studies are considered in view of more recent information. Some of the older ob servations provided fundamental insights and paved the way for present day research; too often such data has been neglected or independently rediscovered. Today, poliovirus research has again attracted considerable interest. High points gained within the last few years were the elucidation of the complete nucleotide sequences of the RNAs of the three poliovinls serotypes and the corresponding vaccine strains, the demonstration of genome evolution during transmission of poliovirus in an epidemic, further characterization of the antigenic sites on the virus particle and of the antigenic drift, characterization of alternate conforma tional states of the virion capsid, the development of monoclonal antibodies against some of the virus proteins, observations on the role of the plasma membrane, cytoskeleton, and cytoplasmic membranes as mediators in the virus induced redirection of the synthetic machinery of the host cell, and characteriza
Molecular Biology Of Picornaviruses
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Author : Bert L. Semler
language : en
Publisher:
Release Date : 2002
Molecular Biology Of Picornaviruses written by Bert L. Semler and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Molecular biology categories.
The Biochemistry Of Poliomyelitis Viruses
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Author : Ernest Kovács
language : en
Publisher: Elsevier
Release Date : 2014-05-16
The Biochemistry Of Poliomyelitis Viruses written by Ernest Kovács and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-16 with Science categories.
The Biochemistry of Poliomyelitis Viruses deals with the interrelationships and differences of positions in the field of poliomyelitis research. This volume presents a general introduction to viruses as to their descriptions and biological, biochemical, and epidemiological aspects. Clinical poliomyelitis, test measurements in the cerebrospinal fluid, and the actions of the poliomyelitis virus are explained. The isolation of the poliomyelitis virus and some aspects of its immunology and serology through refinements of serologic tools and special techniques, plus the state of poliovirus purification, are noted. This book also gives assumptions about the virus' synthetic activities in vivo based on experiments conducted in other viral diseases other than the polio virus. This text also notes that important discoveries such as those made by Gierer and Schramm or Fraenkel-Conrat provide updated poliomyelitis research. Other research studies are taken into consideration and emphasis is given to the biochemical concept of the polio infection and the related features induced during infection such as the presence of tumors. The most promising trend in research is in the study of enzymes of infected cells leading to an understanding of the biochemistry of viral diseases. The use of inference microscopy and X-ray analysis of cell mass is recommended. This book will prove invaluable for microbiologists, disease investigators, clinical workers, and research scientists.
Poliovirus
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Author : Javier Martín
language : en
Publisher:
Release Date : 2015
Poliovirus written by Javier Martín and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with Infectious diseases categories.
This volume introduces the reader to the field of systems medicine by defining its terminology, and describing how established computational methods from bioinformatics and systems biology can be taken forward to establish integrative systems medicine approaches. Systems Medicine provides an outlook on the role that systems medicine may or should play in various medical fields. Describing different facets of the systems medicine approach in action, including examples related to human metabolism, chronic obstructive pulmonary disease, the RNAs in biomedicine and regenerative stem cell medicine. Chapters also introduce tools, resources and methodologies from bioinformatics and systems biology, and shows how to apply these in a systems medicine project. Written for the Methods in Molecular Biology series, chapters include introductions to their respective topics, and discuss experimental and computational approaches, methods, and tools that should be considered for a successful systems medicine project. Systems Medicine aims to motivate and provide guidance for collaborations across disciplines to tackle today's challenges related to human health and well-being.
Molecular Biology Of Picornaviruses
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Author : Bert L. Semler
language : en
Publisher:
Release Date : 2002
Molecular Biology Of Picornaviruses written by Bert L. Semler and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Picornavirus infections categories.
-- Up-to-date and in-depth analysis.
The Molecular Biology Of Picornaviruses
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Author : R. Perez-Bercoff
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-09
The Molecular Biology Of Picornaviruses written by R. Perez-Bercoff and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-09 with Science categories.
vi The intent, therefore, was to provide for a fresh and original review of all relevant topics and issues in the field, following a comprehensive and coherent programme. Such an ambitious goal could only be reached thanks to the unlimited collaboration of the lecturers: They were requested to produce nothing less than "freer, broader, speculative and personal "considerations of the subjects" they had to cover ••• And so they did: their presentations unfolded a fantastic picture, a most fascinating and meaningful identification of the field, its present problems and trends. But participants at this conference contributed many valuable observations while discussing specific points. Unfortunately, more often than not, it proved impossible to identify them in the records. Accordingly, we incorporated here and there some of these "anonymous" contributions as part of the edited version of the texts. To all of the participants, I would like to express my gratitude for their actively taking part in all the scientific (and social ••• ) activities (lectures, round tables, posters, encounters) of this N.A.T.O. ASl. The result was a stimulating atmosphere, conducive to authentic scientific exchanges. Hence, the success of this meeting should be credited only to them. Finally, on behalf of all participants, I would like to thank Professor Sissini, the Mayor of Maratea, and Mr. B. Vitolo, the Chairman of its Tourist Office: their enthusiastic support greatly contributed to make of our time in their wonderful seaside resort an unforgettable one.
The Molecular Biology Of Viruses
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Author : John Colter
language : en
Publisher: Elsevier
Release Date : 2012-12-02
The Molecular Biology Of Viruses written by John Colter and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.
The Molecular Biology of Viruses is a collection of manuscripts presented at the Third Annual International Symposium of the Molecular Biology of Viruses, held in the University of Alberta, Canada on June 27-30, 1966, sponsored by the Faculty of Medicine of the University of Alberta. This book is organized into eight parts encompassing 36 chapters that emphasize the biosynthetic steps involved in polymer duplication. The first two parts explore the specialized processes of the cycle of virulent and temperate bacteriophage multiplication. These parts also deal with the production, regulation of development, and selectivity of these bacteriophages. The subsequent two parts look into the heterozygosity, mutation, structure, function, and mode of infection of single-stranded DNA and RNA bacteriophages. The discussions then shift to the biological and physicochemical aspects, biosynthesis, translation, genetics, and replication of mammalian DNA and RNA viruses. The concluding parts describe the homology, interaction, functions, mechanism of transformation, metabolism, and carcinogenic activity of oncogenic viruses. This book is of great benefit to biochemists, biophysicists, geneticists, microbiologists, and virologists.
Progress In Polio Eradication
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Author : Fred Brown
language : en
Publisher: S. Karger AG (Switzerland)
Release Date : 2001
Progress In Polio Eradication written by Fred Brown and has been published by S. Karger AG (Switzerland) this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with Medical categories.
Volume 105 of Developments in Biologicals reports scientific presentations on the latest progress in polio eradication and vaccination given at an international symposium held in June 2000. The following topics are covered: - the highly impressive progress towards global eradication and the role of the WHO Polio Eradication Program - the efficiency and reliability of virological surveillance and the scientific basis for certification of eradication, including perspectives from countries in the developing world as well as from the developed - updates on the molecular biology and genetics of poliovirus and poliovaccines, including the molecular basis for attenuation and reversion to virulence and the interesting area of receptor specificity for polio and other enteroviruses - the advantages and disadvantages of current poliovaccines and immunization strategies, reviewed by participants from industry and public health organizations - the role of inactivated poliovaccines in the end game and the vexed question of when and how vaccination against polio can be safely suspended as well as the risks of re-introduction of polio post-eradication and post-vaccination - gaps in scientific knowledge in the fields of virology, immunology and epidemiology relevant to the end game of polio eradication and priorities for future scientific research This volume will remain a key reference on polio eradication and vaccination for many years to come, not only for academic researchers but also for members of public health organizations, vaccine manufacturers and managers of immunization programs.
Exploring The Role Of Antiviral Drugs In The Eradication Of Polio
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2006-05-04
Exploring The Role Of Antiviral Drugs In The Eradication Of Polio written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-05-04 with Medical categories.
Exploring the Role of Antiviral Drugs in the Eradication of Polio: Workshop Report, is a report of a workshop in which experts evaluated whether an antiviral drug against poliovirus would be helpful in the final stages of the global polio eradication campaign. The World Health Organization currently plans to stop using oral polio vaccine three years after the detection of the last case of transmission of wild polio virus. This is because the vaccine contains live, weakened polio viruses that can spread and revert to virulence in populations that have not been immunized. Under this plan, an antiviral drug could be useful to control any polio outbreaks caused by a vaccine-derived virus that might occur after vaccination ends and the number of unimmunized people in the world steadily increases. The report recommends that planning and development of such drugs should be initiated now. It identifies several promising targets for drug development and outlines the steps needed for planning for clinical trials and regulatory approval.
Picornaviruses
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Author : Vincent R. Racaniello
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Picornaviruses written by Vincent R. Racaniello and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
This volume provides a comprehensive, up-to-date review of the most active areas in picornavirus research. Included are chapters on picornavirus receptors, translation, protein processing, RNA replication, antigenic structure, and genetics. The work described represents the fruit of technological advances in the field realized at the beginning of the 1980's, and provides an outline for future experimentation.