The Neurobiology Of The Gilles De La Tourette Syndrome And Chronic Tics Part A
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The Neurobiology Of The Gilles De La Tourette Syndrome And Chronic Tics Part A
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Author :
language : en
Publisher: Academic Press
Release Date : 2022-07-06
The Neurobiology Of The Gilles De La Tourette Syndrome And Chronic Tics Part A written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-07-06 with Science categories.
The Neurobiology of the Gilles de la Tourette Syndrome and Chronic Tics, Volume Three reviews historical background and current nosology and guidelines. In addition, it includes an overview of pathophysiology, ranging from its genetic basis and changes in neurochemistry and electrophysiology to widespread neural circuits. Specific chapters cover Tourette syndrome from phenomenology and natural history to neurobiology, Update and Recent progress in the Neurobiology of Tourette Syndrome, Current guidelines and nosology of Tourette syndrome, Neuroimaging applications in Tourette's Syndrome, Clinical and neurodevelopmental brain imaging of Tourette syndrome, Altered Structural Connectivity in Gilles de la Tourette Syndrome, and much more. The last 20?years have seen an exponential growing body of research dedicated to Gilles de la Tourette Syndrome in the understanding of the syndrome’s complex genetics and underlying neurobiology. This unprecedented surge in basic and clinical research has resulted in over 3,000 scientific publications. Examines Gilles de la Tourette Syndrome at behavioral, cognitive, clinical, electrophysiological, molecular and genetic levels Provides a comprehensive overview of the neurobiological aspects of Gilles de la Tourette Syndrome Edited and authored by top researchers and clinicians treating the Gilles de la Tourette Syndrome
The Neurobiology Of The Gilles De La Tourette Syndrome And Chronic Tics Part B
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Author :
language : en
Publisher: Academic Press
Release Date : 2022-09-03
The Neurobiology Of The Gilles De La Tourette Syndrome And Chronic Tics Part B written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-09-03 with Technology & Engineering categories.
The Neurobiology of the Gilles de la Tourette Syndrome and Chronic Tics, Part B, Volume Four reviews historical background, current nosology and guidelines. In addition, it includes an overview of pathophysiology, ranging from its genetic basis and changes in neurochemistry and electrophysiology to widespread neural circuits. Specific chapters cover The genetic basis of Gilles de la Tourette Syndrome, Genome-wide association study of Tourette Syndrome, De Novo mutations in Tourette Syndrome, Animal models for Tourette Syndrome, The neural-immune crosstalk in Tourette syndrome: from immunobiology to epistemology, Functional connectivity in the Gilles de la Tourette Syndrome, and much more. Includes examines of Gilles de la Tourette Syndrome at behavioral, cognitive, clinical, electrophysiological, molecular and genetic levels Provides a comprehensive overview of the neurobiological aspects of Gilles de la Tourette Syndrome Edited and authored by top researchers and clinicians treating Gilles de la Tourette Syndrome
The Neurobiology Of The Gilles De La Tourette Syndrome And Chronic Tics Part A
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Author :
language : en
Publisher: Academic Press
Release Date : 2022-07-25
The Neurobiology Of The Gilles De La Tourette Syndrome And Chronic Tics Part A written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-07-25 with Technology & Engineering categories.
The Neurobiology of the Gilles de la Tourette Syndrome and Chronic Tics, Volume Three reviews historical background and current nosology and guidelines. In addition, it includes an overview of pathophysiology, ranging from its genetic basis and changes in neurochemistry and electrophysiology to widespread neural circuits. Specific chapters cover Tourette syndrome from phenomenology and natural history to neurobiology, Update and Recent progress in the Neurobiology of Tourette Syndrome, Current guidelines and nosology of Tourette syndrome, Neuroimaging applications in Tourette's Syndrome, Clinical and neurodevelopmental brain imaging of Tourette syndrome, Altered Structural Connectivity in Gilles de la Tourette Syndrome, and much more. The last 20?years have seen an exponential growing body of research dedicated to Gilles de la Tourette Syndrome in the understanding of the syndrome's complex genetics and underlying neurobiology. This unprecedented surge in basic and clinical research has resulted in over 3,000 scientific publications.
The Neurobiology And Genetics Of Gilles De La Tourette Syndrome New Avenues Through Large Scale Collaborative Projects
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Author : Peristera Paschou
language : en
Publisher: Frontiers Media SA
Release Date : 2018-03-13
The Neurobiology And Genetics Of Gilles De La Tourette Syndrome New Avenues Through Large Scale Collaborative Projects written by Peristera Paschou and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-03-13 with categories.
Gilles de la Tourette Syndrome (TS) is a common, albeit severely under-diagnosed, neuropsychiatric disorder that is caused by a complex genetic basis, interacting with environmental factors. High comorbidity rates with other neurodevelopmental disorders such as attention deficit/hyperactivity disorder and obsessive compulsive disorder raise the intriguing hypothesis of a shared etiological background. Abnormalities of corticostriatal-thalamic-cortical circuits (CSTC) and dysfunction of both dopamine and serotonin neurotransmitter systems are assumed to be associated with TS. Recently, multiple lines of evidence also point towards an important role of additional neurotransmitters such as histamine and glutamate. For a very long time, efforts to elucidate the etiology and pathophysiology of TS have been fragmented and hampered by low statistical power. Finally, after more than two decades of active research aiming to identify the etiology and pathophysiology of TS, we are on the verge of a new era, promising exciting and rapid discoveries in the field. Investigators from around the world, representing multiple disciplines and scientific approaches, are joining their efforts in large-scale initiatives supported both by European Union and US National funding agencies, such as the European-funded EMTICS, TACTICS, and TSGeneSEE consortia, the Marie Curie Initial Training Network TS-EUROTRAIN and the European Society for the Study of TS joining forces with the NIH-funded TSAICG, GGRI, and Tic Genetics consortia. Importantly, all these initiatives are supported by TS patient support and advocacy groups. Multiple resources are being consolidated and coming together to serve the study of TS, including large well-characterized patient cohorts, and specialized epidemiological databases, such as the unique resource of the Netherlands Twin Register. This research topic showcases current large-scale collaborative efforts aiming to elucidate the genetic and neurobiological background of TS, through diverse approaches; from genomewide association studies aiming to identify common variants associated to the disorder to neuroimaging studies and animal models. Furthermore, current approaches on the clinical assessment and management of the disorder are presented. Propelled by the gradual availability of large scale TS cohorts, novel methodologies, and importantly, sheer enthusiasm by multiple researchers working together across different countries, the new era of the neurobiology of TS holds the promise to identify novel targets for improved therapies.
Handbook Of Tourette S Syndrome And Related Tic And Behavioral Disorders
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Author : Roger Kurlan
language : en
Publisher: CRC Press
Release Date : 2004-10-27
Handbook Of Tourette S Syndrome And Related Tic And Behavioral Disorders written by Roger Kurlan and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-10-27 with Medical categories.
Relating breakthroughs in phenomenology and neurobiology and current strategies for diagnosis, assessment, and clinical care, this long-anticipated Second Edition provides expanded descriptions of clinical features, further evidence linking heritability to etiology, and revised epidemiological estimates as observed in the most recent research on To
Tourette Syndrome
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Author : Davide Martino
language : en
Publisher: Oxford University Press
Release Date : 2022
Tourette Syndrome written by Davide Martino and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022 with Medical categories.
Tourette syndrome (TS) has become increasingly recognised within society and has gained scientific interest worldwide. Knowledge of its clinical presentation, mechanisms of disease, and available treatment approaches has increased remarkably over the last two decades. Likewise, the way clinicians, teachers, social care workers, and families face the problems manifested by patients with TS is rapidly evolving. Tourette Syndrome, edited by Davide Martino and James F. Leckman, offers a unique opportunity to capture this knowledge advance through a comprehensive and up-to-date overview. Tourette Syndrome covers all the main aspects related to TS, analyzing its complex clinical presentation, the novel viewpoints of causes and mechanisms, state-of-the-art assessment techniques, and the diversity of treatment options. Multidisciplinarity is the main asset of this volume, which represents a source of consultation for a wide audience of professionals, integrated with video tutorials related to particularly complex areas of patient management. Medical and PhD students, as well as post-doctoral scientists, will be able to use the volume as a valuable learning source.
The Neurobiology And Genetics Of Gilles De La Tourette Syndrome New Avenues Through Large Scale Collaborative Projects
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Author :
language : en
Publisher:
Release Date : 2018
The Neurobiology And Genetics Of Gilles De La Tourette Syndrome New Avenues Through Large Scale Collaborative Projects written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018 with categories.
Gilles de la Tourette Syndrome (TS) is a common, albeit severely under-diagnosed, neuropsychiatric disorder that is caused by a complex genetic basis, interacting with environmental factors. High comorbidity rates with other neurodevelopmental disorders such as attention deficit/hyperactivity disorder and obsessive compulsive disorder raise the intriguing hypothesis of a shared etiological background. Abnormalities of corticostriatal-thalamic-cortical circuits (CSTC) and dysfunction of both dopamine and serotonin neurotransmitter systems are assumed to be associated with TS. Recently, multiple lines of evidence also point towards an important role of additional neurotransmitters such as histamine and glutamate. For a very long time, efforts to elucidate the etiology and pathophysiology of TS have been fragmented and hampered by low statistical power. Finally, after more than two decades of active research aiming to identify the etiology and pathophysiology of TS, we are on the verge of a new era, promising exciting and rapid discoveries in the field. Investigators from around the world, representing multiple disciplines and scientific approaches, are joining their efforts in large-scale initiatives supported both by European Union and US National funding agencies, such as the European-funded EMTICS, TACTICS, and TSGeneSEE consortia, the Marie Curie Initial Training Network TS-EUROTRAIN and the European Society for the Study of TS joining forces with the NIH-funded TSAICG, GGRI, and Tic Genetics consortia. Importantly, all these initiatives are supported by TS patient support and advocacy groups. Multiple resources are being consolidated and coming together to serve the study of TS, including large well-characterized patient cohorts, and specialized epidemiological databases, such as the unique resource of the Netherlands Twin Register. This research topic showcases current large-scale collaborative efforts aiming to elucidate the genetic and neurobiological background of TS, through diverse approaches; from genomewide association studies aiming to identify common variants associated to the disorder to neuroimaging studies and animal models. Furthermore, current approaches on the clinical assessment and management of the disorder are presented. Propelled by the gradual availability of large scale TS cohorts, novel methodologies, and importantly, sheer enthusiasm by multiple researchers working together across different countries, the new era of the neurobiology of TS holds the promise to identify novel targets for improved therapies.
Advances In The Neurochemistry And Neuropharmacology Of Tourette Syndrome
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Author :
language : en
Publisher: Academic Press
Release Date : 2013-11-27
Advances In The Neurochemistry And Neuropharmacology Of Tourette Syndrome written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-27 with Medical categories.
This volume of International Review of Neurobiology brings together cutting-edge research on advances in the neurochemistry and neuropharmacology of Tourette syndrome. It reviews current knowledge and understanding, provides a starting point for researchers and practitioners entering the field, and includes important topics regards tics, neurotransmitters, pharmacology and emerging treatments. This volume of brings together research on tourettes synrdrome. It reviews current knowledge and understanding on the neurochemistry and neuropharmacology of tourettes syndrome
Tourette Syndrome
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Author : John T. Walkup
language : en
Publisher: Lippincott Williams & Wilkins
Release Date : 2006
Tourette Syndrome written by John T. Walkup and has been published by Lippincott Williams & Wilkins this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Medical categories.
This volume provides a summary review of all recently published and ongoing research initiatives related to Tourette Syndrome. The latest research is presented in a clinical context, and controversial issues are fully discussed using an evidence-based approach. These issues include the prevalence of TS, the nature of the TS phenotype, the role of autoimmunity in the development of TS, the role of comorbidity in functional outcomes of TS patients, and approaches to identifying the TS gene/genes. Chapters describe recent advances in neuroimaging, genetics, and treatment. The book includes extensive discussions of co-morbid disorders: obsessive-compulsive disorder, attention deficit hyperactivity disorder, mood disorders, and tics.
Tourette Syndrome
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Author : Thomas Newell Chase
language : en
Publisher: Lippincott Williams & Wilkins
Release Date : 1992
Tourette Syndrome written by Thomas Newell Chase and has been published by Lippincott Williams & Wilkins this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with Medical categories.
This volume presents an encyclopedic account of the past decade's achievements in the study and treatment of Tourette Syndrome (TS) and associated behavioral and psychiatric disorders. More than 90 of the foremost authorities from all relevant basic science, clinical, and behavioral science disciplines highlight the major recent developments worldwide - from groundbreaking genetic and neurochemical research and studies using state-of-the-art neuroimaging technologies, to new concepts on the clinical spectrum and natural history of TS, increasing recognition of comorbid conditions, and improved strategies for pharmacotherapy and psychosocial management. The contributors assess the practical utility of current diagnostic criteria for TS and present extensive data on its natural history, its range of clinical manifestations, and its associated disorders. The findings indicate that the severity of TS varies widely among patients, that tics tend to diminish during adolescence and adulthood, and that comorbid conditions - such as obsessive-compulsive disorder and attention deficit hyperactivity disorder - are often the chief source of impairment. Much evidence suggests that these disturbances and the tics are manifestations of the same underlying diathesis. Noted investigators document significant findings on the mode of inheritance for TS, define the key methodological issues in genetic linkage studies, and describe molecular approaches to the search for the genetic locus for the syndrome. The book also includes new data implicating specific monoamine neurotransmitters and endogenous opioid peptides in the pathogenesis of TS. Other contributors present neuroimaging studies using MRI, PET, and SPECT to delineate brain mechanisms involved in TS. The book offers definitive guidelines on pharmacotherapy for tics and, particularly, for associated obsessive-compulsive disorder (OCD) and attention deficit hyperactivity disorder (ADHD). Of special note are the discussions on treatment of OCD with serotonin reuptake inhibitors and on use of clonidine and stimulants for ADHD with comorbid tics. Additional chapters explore the potential of novel drugs and of nutritional interventions such as megavitamin therapy. Full consideration is also given to the role of behavioral and psychosocial therapies and the educational management of children with TS. This volume is an indispensable resource for all clinicians and investigators involved in the treatment or study of neuropsychiatric disorders. It exemplifies the creative application of the full range of current neuroscience and behavioral methodologies to a complex and important syndrome.