The New Generation Of Quinolones
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The New Generation Of Quinolones
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Author : Siporin
language : en
Publisher: CRC Press
Release Date : 1990-08-28
The New Generation Of Quinolones written by Siporin and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990-08-28 with Medical categories.
Surveys the newest members of a family of antimicrobial drugs increasingly being used to treat infections of the urinary tract, lungs, skin, bones, and diarrheal diseases. The drugs have been developed only since the 1960s, and still pose many questions about resistance and toxic and developmental s
The Quinolones
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Author : Vincent T. Andriole
language : en
Publisher: Elsevier
Release Date : 2000-10-09
The Quinolones written by Vincent T. Andriole and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-10-09 with Medical categories.
Quinolones constitute a large class of synthetic antimicrobial agents that are highly effective in the treatment of many types of infectious diseases, particularly those caused by bacteria. New quinolones are continually being developed as bacterial species develop resistance to existing quinolones. This book presents the most current information available in our continual struggle to conquer disease. Over time, bacteria become resistant to medicines that are used to combat them. Because of this, the medical world is always in search of new and improved ways to battle these disease-causing bacteria. Quinolones are at the forefront of this research. Edited by one of the world's foremost authorities on the subject, the third edition of this highly successful title will serve as a valuable tool for primary care physicians and researchers interested in a comprehensive, up-to-date reference on the chemistry, mechanisms of action, development of resistance, and clinical efficacy of both currently available and newer quinolone compounds under investigation. This is the eagerly anticipated fully revised edition of the standard reference in the field. Eagerly anticipated updated edition of noted title covering synthetic microbial agents that are useful against infectious disease, particularly those caused by bacteria Edited by one of the foremost experts in the field of quinolone research and infectious disease History of quinolones, chemistry & mechanisms of action, pharmacology, safety aspects Role of quinolones in treating various types of infections, including respiratory infections, gastrointestinal infections, urinary tract infections, prostatitis, STDs and bacterial meningitis as well as their use in immunocompromised patients
Trovafloxacin
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Author : J.A. García Rodríguez
language : en
Publisher:
Release Date : 1997
Trovafloxacin written by J.A. García Rodríguez and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997 with categories.
Achilles Tendon Disorders
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Author : Jón Karlsson
language : en
Publisher:
Release Date : 2014
Achilles Tendon Disorders written by Jón Karlsson and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with Achilles tendon categories.
Quinolone Antimicrobial Agents
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Author : David C. Hooper
language : en
Publisher:
Release Date : 1993
Quinolone Antimicrobial Agents written by David C. Hooper and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Medical categories.
Quinolones remain the most important class of antimicrobial agents discovered in recent years – over 1000 have been synthesized and evaluated. Since the publication of the original edition, considerable strides have been made in the research on structure–activity relationships, mechanism of action, resistance, pharmacodynamics and drug interactions. This edition consolidates and substantially updates our current state of knowledge of quinolones, with thirteen new chapters having been added.
Antimicrobial Resistance In Agriculture
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Author : Indranil Samanta
language : en
Publisher: Academic Press
Release Date : 2019-09-25
Antimicrobial Resistance In Agriculture written by Indranil Samanta and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-25 with Medical categories.
Antimicrobial Resistance in Agriculture: Perspective, Policy and Mitigation is a valuable industrial resource that addresses complex, multi-factorial topics regarding farm, wild, companion animals, fish, and how the environment plays an important role in amplification and transmission of resistant bugs into the human food chain. Information of phenotypical and genotypical properties of each bacterial genus associated with antimicrobial resistance, transmission dynamics from different reservoirs (food animals, poultry, fishes) and control measures with alternative therapy, such as phytobiotics and nanomaterials are provided. Researchers, scientists and practitioners will find this an essential resource on the judicial use of antibiotics in animals and humans. Explores all the genera of livestock and fish originated pathogenic bacteria associated with antimicrobial resistance Presents cutting-edge research on epigenetics, nanotechnology and intervention technologies Discusses transmission dynamics of resistance gene pools from different reservoirs, including food animals, poultry, fishes and the environment
Quinolone Antibacterials
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Author : Jochen Kuhlmann
language : en
Publisher: Springer
Release Date : 2012-02-12
Quinolone Antibacterials written by Jochen Kuhlmann and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-02-12 with Medical categories.
It has been over 30 years since the first clinically important member of the quinolone class, nalidixic acid, was introduced into medical practice. The modification produced in the quinolone nucleus by introducing a fluorine at the 6-position led to the discovery of the newer fluoroquinolones with enhanced antibacterial activities as compared to nalidixic acid. By now a great deal of preclinical and clinical experience has been obtained with these agents. The intense interest in this class of antibacterial agents by chemists, micro biologists, toxicologists, pharmacologists, clinical pharmacologists, and clini cians in various disciplines encouraged us to summarize the information on the history, chemistry, mode of action and in vitro properties, kinetics and efficacy in animals, mechanisms of resistance, toxicity, clinical pharmacology, clinical experience, and future prospects in one volume of the Handbook of Experimental Pharmacology. As this series deals predominantly with "experimental" characteristics of drugs, our volume is dedicated specifically to quinolones and emphasizes principally their preclinical and clinical phar macological characteristics, despite the existence of several summaries on quinolones. The chemistry of the quinolones is described in detail. The chapter on the mode of action of quinolones reports the conclusive evidence that gyrase is the intracellular target of the quinolones; however, another enzyme, topoisomerase IV, may also be a target for quinolones, and the exact mechanisms by which quinolones act bactericidally are far from being understood.
Drug Induced Liver Injury
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Author :
language : en
Publisher: Academic Press
Release Date : 2019-07-13
Drug Induced Liver Injury written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-13 with Medical categories.
Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. Includes the authority and expertise of leading contributors in pharmacology Presents the latest release in the Advances in Pharmacology series
Introduction To Basics Of Pharmacology And Toxicology
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Author : Abialbon Paul
language : en
Publisher: Springer Nature
Release Date : 2021-03-13
Introduction To Basics Of Pharmacology And Toxicology written by Abialbon Paul and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-13 with Medical categories.
This book explains the pharmacological relationships between the various systems in the human body. It offers a comprehensive overview of the pharmacology concerning the autonomic, central, and peripheral nervous systems. Presenting up-to-date information on chemical mediators and their significance, it highlights the therapeutic aspects of several diseases affecting the cardiovascular, renal, respiratory, gastrointestinal, endocrinal, and hematopoietic systems. The book also includes drug therapy for microbial and neoplastic diseases. It also comprises sections on immunopharmacology, dermatological, and ocular pharmacology providing valuable insights into these emerging and recent topics. Covering the diverse groups of drugs acting on different systems, the book reviews their actions, clinical uses, adverse effects, interactions, and subcellular mechanisms of action. It is divided into 11 parts, subdivided into several chapters that evaluate the basic pharmacological principles that govern the different types of body systems. This book is intended for academicians, researchers, and clinicians in industry and academic institutions in pharmaceutical, pharmacological sciences, pharmacy, medical sciences, physiology, neurosciences, biochemistry, molecular biology and other allied health sciences.
Contemporary Drug Synthesis
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Author : Jie Jack Li
language : en
Publisher: John Wiley & Sons
Release Date : 2004-12-27
Contemporary Drug Synthesis written by Jie Jack Li and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-12-27 with Science categories.
An integrated and insightful look at successful drug synthesis in today's drug discovery market The pharmaceutical industry is unquestionably vibrant today, with drug synthesis making a vital contribution. Whether in the early developmental stages of identifying and optimizing a lead, or the latter stages of process development and cost-effective scale-up, the ability to design elegant and economical synthetic routes is often a major factor in the eventual viability and commercial success of a drug. Contemporary Drug Synthesis examines how leading researchers and manufacturers have integrated chemistry, biology, pharmacokinetics, and a host of other disciplines in the creation and development of leading drugs. Authored by four of the pharmaceutical industry's most respected scientists, this timely volume: Focuses on the processes that resulted in high-profile drugs including Lipitor, Celebrex, Viagra, Gleevec, Nexium, Claritin, and over a dozen others Provides an in-depth introduction to each drug, followed by a detailed account of its synthesis Organizes the drugs into fourteen therapeutic areas for clarity and ease of use Process chemists provide an essential bridge between chemistry and the marketplace, creating scientifically practical drug processes while never losing sight of the commercial viability of those processes. Contemporary Drug Synthesis meets the needs of a growing community of researchers in pharmaceutical research and development, and is both a useful guide for practicing pharmaceutical scientists and an excellent text for medicinal and organic chemistry students.
