The Orexin System Basic Science And Role In Sleep Pathology
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The Orexin System Basic Science And Role In Sleep Pathology
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Author : M.A. Steiner
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2021-05-28
The Orexin System Basic Science And Role In Sleep Pathology written by M.A. Steiner and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-05-28 with Health & Fitness categories.
The orexin system, discovered in 1998, has emerged as a crucial player in regulating the sleep and wake balance inside our brain. This discovery has sparked a burst of novel and dynamic research on the physiology and pathology of sleep. The Orexin System: Basic Science and Role in Sleep Pathology honors this research and the authors share their ideas and perspectives on the novel developments within the field. The book examines the intricate role of the orexin system in regulating sleep and wake, and its interaction with other wake-regulating systems. The orexin system is dissected at the cellular and molecular level to explore the diversity of the orexin-producing neurons, their projections, and their signaling pathways. Additionally, the book discusses the diseases which are associated with a dysfunctional orexin system, such as narcolepsy, insomnia, substance abuse, and Alzheimer’s disease, and explores the new potential therapeutic applications derived from the burst of research around this fascinating system. This publication is essential reading for neurobiologists, neurologists, psychopharmacologists, sleep researchers, and other researchers and clinical scientists interested in sleep, sleep research, insomnia, and medicine in general.
Atlas Of Clinical Sleep Medicine E Book
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Author : Meir H. Kryger
language : en
Publisher: Elsevier Health Sciences
Release Date : 2022-12-14
Atlas Of Clinical Sleep Medicine E Book written by Meir H. Kryger and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-12-14 with Medical categories.
Easy to read and richly illustrated, Atlas of Clinical Sleep Medicine, 3rd Edition, provides the tools you need to accurately diagnose and treat the full range of adult and pediatric sleep disorders. Dr. Meir H. Kryger and a team of expert contributing authors detail the physiologic, clinical, morphologic, and investigational aspects of the sleep disorders you encounter in everyday practice—enhanced by high-quality images throughout. This highly regarded, award-winning atlas is an ideal resource for sleep practitioners and technicians in the lab, as well as an effective review for certification and recertification. - Features a thoroughly illustrated, reader-friendly format that highlights key details, helping you interpret the visual manifestations of your patients' sleep disorders so you can manage them most effectively. - Contains the most up-to-date drug therapy with information about the latest drugs available as well as those in clinical trials. - Provides greater coverage of pediatric and adolescent disorders, including behavioral insomnia, new medication options, and multiple sleep latency testing (MSLT) specific to children. - Includes current AASM scoring guidelines and diagnostic criteria. - Presents correlations between normal and abnormal sleep relative to other health issues such as stroke and heart failure. - Illustrates the physiology of sleep with full-color images (many are new!) and correlates the physiology with the relevant findings. - Provides numerous resources online, including more than 80 patient interview and sleep lab videos and 200+ polysomnogram fragments.
Pharmacological Advances In Central Nervous System Stimulants
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Author :
language : en
Publisher: Elsevier
Release Date : 2024-03-09
Pharmacological Advances In Central Nervous System Stimulants written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-03-09 with Medical categories.
Pharmacological Advances in Central Nervous System Stimulants, Volume 99 in the Mechanisms, Therapeutic Uses, and Abuse of Stimulants series, showcases recent pharmacological progress investigating both therapeutic (ADHD, binge-eating and narcolepsy) and abuse aspects of a number of stimulants, some of which are long-standing (amphetamines, cocaine and nicotine) while others are emerging (cathinones). Specific chapters in this new release include Transgenerational Epigenetic Inheritance of Phenotypes Associated with Parental Exposure to Drugs of Abuse, Dysregulation Of Brain Cholesterol Homeostasis by Psychostimulants, Modeling Methamphetamine Use Disorder in Mammals: Sex Differences in Behavioral Consequences and Gene Expression, and much more.Additional sections focus on Second Generation Stimulants – Pharmacological and Clinical Advances in The Treatment of ADHD And Binge-eating disorder, Pharmacology Of Stimulant – Opioid Co-Use, Role Of Age and Sex in Determining the Risk For Adverse Consequences Following Exposure To Amphetamines, Modafinil, An Atypical CNS Stimulant, Modulators Of Nicotine Reward-Related and Reinforcement-Related Behaviors, Methamphetamine Effects on Peripheral Immune System, Post-Translational Mechanisms in Neurotransmitter Efflux, The Many Enigmas of Nicotine, Genetic Variation in The Neuregulin-Erbb Signaling Pathway And Substance Use Disorders, Pharmacology And Neurotoxicology of Synthetic Cathinones, and more. - Provides a diverse variety of stimulants, having different mechanisms of action and physiological effects - Includes both therapeutic uses and abuse aspects of stimulants - Covers both molecular mechanisms and behavioral effects of stimulants
Sleep Disorders And Sleep Deprivation
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2006-10-13
Sleep Disorders And Sleep Deprivation written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-10-13 with Medical categories.
Clinical practice related to sleep problems and sleep disorders has been expanding rapidly in the last few years, but scientific research is not keeping pace. Sleep apnea, insomnia, and restless legs syndrome are three examples of very common disorders for which we have little biological information. This new book cuts across a variety of medical disciplines such as neurology, pulmonology, pediatrics, internal medicine, psychiatry, psychology, otolaryngology, and nursing, as well as other medical practices with an interest in the management of sleep pathology. This area of research is not limited to very young and old patientsâ€"sleep disorders reach across all ages and ethnicities. Sleep Disorders and Sleep Deprivation presents a structured analysis that explores the following: Improving awareness among the general public and health care professionals. Increasing investment in interdisciplinary somnology and sleep medicine research training and mentoring activities. Validating and developing new and existing technologies for diagnosis and treatment. This book will be of interest to those looking to learn more about the enormous public health burden of sleep disorders and sleep deprivation and the strikingly limited capacity of the health care enterprise to identify and treat the majority of individuals suffering from sleep problems.
Hypocretins
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Author : Luis De Lecea
language : en
Publisher: Springer
Release Date : 2014-11-27
Hypocretins written by Luis De Lecea and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-11-27 with Medical categories.
The first report that rapid eye movements occur in sleep in humans was published in 1953. The research journey from this point to the realization that sleep consists of two entirely independent states of being (eventually labeled REM sleep and non-REM sleep) was convoluted, but by 1960 the fundamental duality of sleep was well established including the description of REM sleep in cats associated with “wide awake” EEG patterns and EMG suppression. The first report linking REM sleep to a pathology occurred in 1961 and a clear association of sleep onset REM periods, cataplexy, hypnagogic hallucinations and sleep paralysis was fully established by 1966. When a naïve individual happens to observe a full-blown cataplexy attack, it is both dramatic and unnerving. Usually the observer assumes that the loss of muscle tone represents syncope or seizure. In order to educate health professionals and the general public, Christian Guilleminault and I made movies of full-blown cataplectic episodes (not an easy task). We showed these movies of cataplexy attacks to a number of professional audiences, and were eventually rewarded with the report of a similar abrupt loss of muscle tone in a dog. We were able to bring the dog to Stanford University and with this as the trigger, we were able to develop the Stanford Canine Narcolepsy Colony. Breeding studies revealed the genetic determinants of canine narcolepsy, an autosomal recessive gene we termed canarc1. Emmanuel Mignot took over the colony in 1986 and began sequencing DNA, finally isolating canarc1 in 1999.
Foundations Of Psychiatric Sleep Medicine
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Author : John W. Winkelman
language : en
Publisher: Cambridge University Press
Release Date : 2010-12-23
Foundations Of Psychiatric Sleep Medicine written by John W. Winkelman and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-12-23 with Medical categories.
Sleep-related complaints are extremely common across the spectrum of psychiatric illness. Accurate diagnosis and management of sleep disturbances requires an understanding of the neurobiological mechanisms underlying sleep and wakefulness, the characteristics of sleep disturbance inherent to psychiatric illness and primary sleep disorders, as well as the psychopharmacologic and behavioral treatments available. Foundations of Psychiatric Sleep Medicine provides a uniquely accessible, practical, and expert summary of current clinical concepts at the sleep-psychiatry interface. Topics covered include: basic principles in sleep science, clinical sleep history taking, primary sleep disorders in psychiatric contexts, and sleep disturbance across a range of mood, anxiety, psychotic, substance use, cognitive and developmental disorders. Written by outstanding experts in the field of sleep medicine and psychiatry, this academically rigorous and clinically useful text is an essential resource for psychiatrists, psychologists and other health professionals interested in the relationship between sleep and mental illness.
The Genetic Basis Of Sleep And Sleep Disorders
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Author : Paul Shaw
language : en
Publisher: Cambridge University Press
Release Date : 2013-10-24
The Genetic Basis Of Sleep And Sleep Disorders written by Paul Shaw and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-24 with Medical categories.
The first comprehensive book on the subject, The Genetic Basis of Sleep and Sleep Disorders covers detailed reviews of the general principles of genetics and genetic techniques in the study of sleep and sleep disorders. The book contains sections on the genetics of circadian rhythms, of normal sleep and wake states and of sleep homeostasis. There are also sections discussing the role of genetics in the understanding of insomnias, hypersomnias including narcolepsy, parasomnias and sleep-related movement disorders. The final chapter highlights the use of gene therapy in sleep disorders. Written by genetic experts and sleep specialists from around the world, the book is up to date and geared specifically to the needs of both researchers and clinicians with an interest in sleep medicine. This book will be an invaluable resource for sleep specialists, neurologists, geneticists, psychiatrists and psychologists.
Keto Marat N 2 Edici N
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Author : Inés Viñas
language : es
Publisher: Ketophile
Release Date : 2024-10-10
Keto Marat N 2 Edici N written by Inés Viñas and has been published by Ketophile this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-10-10 with Cooking categories.
Una década de estudio obsesivo condensada en 12 horas... y un delicioso menú semanal. ¿Has decidido aventurarte por el mundillo keto? ¡Pues esto te interesa! Afortunadamente, hace ya un montón de años que descubrí la dieta cetogénica. Y hoy creo haber cometido todos los errores imaginables. Por eso nació la Keto-Maratón: para ahorrártelos a ti. Ojalá te ayude a allanar tu camino.
Sleep And Movement Disorders
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Author : Sudhansu Chokroverty
language : en
Publisher: Oxford University Press
Release Date : 2013-08-15
Sleep And Movement Disorders written by Sudhansu Chokroverty and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-08-15 with Health & Fitness categories.
Sleep disorders and movement disorders are inter-connected areas of neurology, and this comprehensive text examines the relationship, the basic science and the latest advances in treatment.
Neuropsychiatric And Cognitive Changes In Parkinson S Disease And Related Movement Disorders
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Author : Dag Aarsland
language : en
Publisher: Cambridge University Press
Release Date : 2013-08-29
Neuropsychiatric And Cognitive Changes In Parkinson S Disease And Related Movement Disorders written by Dag Aarsland and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-08-29 with Medical categories.
A broad and in-depth discussion of the important, but still uninformed, field of behavioral disturbances associated with Parkinson's disease.