The Pathogenic Yersiniae Advances In The Understanding Of Physiology And Virulence Volume Ii

DOWNLOAD

Download The Pathogenic Yersiniae Advances In The Understanding Of Physiology And Virulence Volume Ii PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get The Pathogenic Yersiniae Advances In The Understanding Of Physiology And Virulence Volume Ii book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page

The Pathogenic Yersiniae Advances In The Understanding Of Physiology And Virulence Volume Ii

DOWNLOAD
Author : Matthew S Francis
language : en
Publisher: Frontiers Media SA
Release Date : 2019-10-09

The Pathogenic Yersiniae Advances In The Understanding Of Physiology And Virulence Volume Ii written by Matthew S Francis and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-10-09 with categories.

Pathogenic Yersinia consist of the prominent human pathogens Y. pestis, Y. enterocolitica, and Y. pseudotuberculosis, the fish pathogen Y. ruckeri, as well as a number of insect pathogens. Facilitated by the ease of in vitro culturing, genetic tractability, and availability of relevant infection models, studies of pathogenic Yersinia have revealed a great deal about physiological processes at the molecular level that contribute to pathogen adaptation to the ever changing environments both inside and outside of the host. Comprehensive genome sequencing analyses has further benefitted understanding of this bacterial pathogen evolution. Critically, many of these detailed molecular studies also identified potential targets for the design and development of anti-bacterial therapeutic drugs that could help to fight the ever-increasing problem of resistance to conventional antibiotics. New developments in several of these areas are highlighted in this edition of the Research Topic “The Pathogenic Yersiniae – Advances in the Understanding of Physiology and Virulence, Second Edition”.

The Pathogenic Yersiniae Advances In The Understanding Of Physiology And Virulence

DOWNLOAD
Author : Matthew S. Francis
language : en
Publisher: Frontiers E-books
Release Date : 2014-08-27

The Pathogenic Yersiniae Advances In The Understanding Of Physiology And Virulence written by Matthew S. Francis and has been published by Frontiers E-books this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-08-27 with Infectious and parasitic diseases categories.

From early studies of the plague causing agent through to comparatively more recent research defining aspects of the type III secretion mechanism, pathogenic Yersinia have served as an inventive model organism for researchers seeking to understand the complexities of bacteria-host cell interactions. In fact, seminal studies on Yersinia virulence mechanisms contributed to the emergence and recognition of the research field – cellular microbiology. Researching Yersinia infection biology continues to bring to light novel discoveries. Assortments of Yersinia whole genome sequencing projects are providing unparalleled insight into bacterial pathogen evolution and environmental adaptation. This is enabling researchers to identify and define more fascinating virulence and/or survival mechanisms that advance and expand existing perceptions of bacterial-host encounters. Current research is also beginning to bring to light how the pathogenic Yersiniae respond to physicochemical environmental cues to spatially and temporally control their armoury of customized virulence/survival factors. This Research Topic is therefore focused on presenting and summarizing new developments in Yersinia pathogenicity through highlighting cutting-edge studies on the Yersinia-host cell interaction and the network of regulatory control mechanisms that define this outcome. It will also endeavour to address how such findings might influence selection of potential targets for the design and development of anti-Yersinia therapeutic drugs and vaccines, as well as identify translational studies that involve unique and rewarding cooperation between diverse disciplines

The Pathogenic Yersiniae Advances In The Understanding Of Physiology And Virulence Volume Ii

DOWNLOAD
Author : Matthew S Francis
language : en
Publisher:
Release Date : 2019

The Pathogenic Yersiniae Advances In The Understanding Of Physiology And Virulence Volume Ii written by Matthew S Francis and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019 with categories.

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Harrison S Principles Of Internal Medicine Twenty First Edition Vol 1 Vol 2

DOWNLOAD
Author : Joseph Loscalzo
language : en
Publisher: McGraw Hill Professional
Release Date : 2022-04-05

Harrison S Principles Of Internal Medicine Twenty First Edition Vol 1 Vol 2 written by Joseph Loscalzo and has been published by McGraw Hill Professional this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-04-05 with Medical categories.

The Voice of Clinical ReasonA Doody's Core Title for 2024 & 2023! Harrison’s Principles of Internal Medicine is the world's most trusted clinical medicine text—and a superb resource for learning the art and science of clinical reasoning. Recognized by healthcare professionals worldwide as the leading authority on applied pathophysiology and clinical medicine, Harrison’s Principles of Internal Medicine provides the informational foundation you need for the best patient care possible. This new edition is fully updated with timely new chapters and essential updates across the spectrum of internal medicine. Harrison's Principles of Internal Medicine stands as the benchmark for authoritative, practical information on patient care and the pathogenesis and clinical management of symptoms and signs and specific diseases. Written and edited by the world’s top experts in their respective fields, this landmark guide provides the comprehensive, accurate, and essential coverage of the pathogenesis, diagnosis, and treatment of disease. Harrison’s is world-renowned as the most authoritative source for: • Descriptions of disease mechanisms and how the clinician can apply that knowledge for the best patient care and optimal diagnosis and treatment of specific diseases • Clear, concise schemas that facilitate the generation of differential diagnoses to reason efficiently through complex real world clinical cases • The physiologic and epidemiologic basis of signs and symptoms, which are covered through a wealth of unsurpassed expert guidance and linked to the disease-specific chapters that follow • Updated clinical trial results and recommended guidelines • Excellent and extensive visual support, including radiographs, clinical photos, schematics, and high-quality drawings • Coverage of both therapeutic approaches and specific treatment regimens • Practical clinical decision trees and algorithms • Organ-specific sections, with clinically relevant pathophysiology and practical clinical advice on the approach to the patient, strategies towards building a differential diagnosis, outstanding clinical algorithms and diagnostic schema, a wealth of clinical images and diagrams, current clinical guidelines, general and specific approaches to therapy Harrison’s remains the most trusted resource in a world influenced by endless sources of medical information. The most timely and comprehensive updates from the world’s top experts are featured in the 21st edition: • Current coverage of the diagnosis and treatment of diseases, from COVID to dementia to sepsis to multiple sclerosis to lung cancer • Updated content that reflects new approved therapeutics and new practice-changing guidelines and evidence summaries • More than 1000 clinical, pathological, and radiographic photographs, diagnostic and therapeutic decision trees, and clear schematics and diagrams describing pathophysiologic processes • More than a dozen atlases featuring curated collections of visual aspects of diagnosis and management • Complete, updated curation and synthesis of primary medical literature which incorporates current data from major studies and clinical trials • Clinical reasoning resources and helpful disease/presentation schemas • Clinically relevant coverage of disease mechanics and pathophysiology, and related therapeutic mechanisms

Cumulated Index Medicus

DOWNLOAD
Author :
language : en
Publisher:
Release Date : 1982

Cumulated Index Medicus written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1982 with Medicine categories.

The Comprehensive Sourcebook Of Bacterial Protein Toxins

DOWNLOAD
Author : Joseph E. Alouf
language : en
Publisher: Elsevier
Release Date : 2005-12-20

The Comprehensive Sourcebook Of Bacterial Protein Toxins written by Joseph E. Alouf and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-12-20 with Science categories.

This book describes the major achievements and discoveries relevant to bacterial protein toxins since the turn of the new century illustrated by the discovery of more than fifty novel toxins (many of them identified through genome screening). The establishment of the three-dimensional crystal structure of more than 20 toxins during the same period offers deeper knowledge of structure-activity relationships and provides a framework to understand how toxins recognize receptors, penetrate membranes and interact with and modify intracellular substrates. - Edited by two of the most highly regarded experts in the field from the Institut Pasteur, France - 14 brand new chapters dedicated to coverage of historical and general aspects of toxinology - Includes the major toxins of both basic and clinical interest are described in depth - Details applied aspects of toxins such as therapy, vaccinology, and toolkits in cell biology - Evolutionary and functional aspects of bacterial toxins evaluated and summarized - Toxin applications in cell biology presented - Therapy (cancer therapy, dystonias) discussed - Vaccines (native and genetically engineered vaccines) featured - Toxins discussed as biological weapons, comprising chapters on anthrax, diphtheria, ricin etc.

Advancements Of Mass Spectrometry In Biomedical Research

DOWNLOAD
Author : Alisa G. Woods
language : en
Publisher: Springer
Release Date : 2019-07-25

Advancements Of Mass Spectrometry In Biomedical Research written by Alisa G. Woods and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-25 with Science categories.

This volume explores the use of mass spectrometry for biomedical applications. Chapters focus on specific therapeutic areas such as oncology, infectious disease, and psychiatry. Additional chapters focus on methodology, technologies and instrumentation, as well as on analysis of protein-protein interactions, protein quantitation, and protein post-translational modifications. Various omics fields such as proteomics, metabolomics, glycomics, lipidomics, and adductomics are also covered. Applications of mass spectrometry in biotechnological and pharmaceutical industry are also discussed. This volume provides readers with a comprehensive and informative manual that will allow them to appreciate mass spectrometry and proteomic research, but also to initiate and improve their own work. This book acts as a technical guide as well as a conceptual guide to the newest information in this exciting field.

Filamentous Bacteriophage In Bio Nano Technology Bacterial Pathogenesis And Ecology

DOWNLOAD
Author : Jasna Rakonjac
language : en
Publisher: Frontiers Media SA
Release Date : 2017-02-16

Filamentous Bacteriophage In Bio Nano Technology Bacterial Pathogenesis And Ecology written by Jasna Rakonjac and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-02-16 with categories.

Filamentous phage (genus Inovirus) infect almost invariably Gram-negative bacteria. They are distinguished from all other bacteriophage not only by morphology, but also by the mode of their assembly, a secretion-like process that does not kill the host. “Classic” Escherichia colifilamentous phage Ff (f1, fd and M13) are used in display technology and bio/nano/technology, whereas filamentous phage in general have been put to use by their bacterial hosts for adaptation to environment, pathogenesis, biofilm formation, horizontal gene transfer and modulating genome stability. Many filamentous phage have a “symbiotic” life style that is often manifested by inability to form plaques, preventing their identification by standard phage-hunting techniques; while the absence or very low sequence conservation between phage infecting different species often complicates their identification through bioinformatics. Nevertheless, the number of discovered filamentous phage is increasing rapidly, along with realization of their significance. “Temperate” filamentous phage whose genomes are integrated into the bacterial chromosome of pathogenic bacteria often modulate virulence of the host. The Vibrio cholerae phage CTXf genome encodes cholera toxin, whereas many filamentous prophage influence virulence without encoding virulence factors. The nature of their effect on the bacterial pathogenicity and overall physiology is the next frontier in understanding intricate relationship between the filamentous phage and their hosts. Phage display has been widely used as a combinatorial technology of choice for discovery of therapeutic antibodies and peptide leads that have been applied in the vaccine design, diagnostics and drug development or targeting over the past thirty years. Virion proteins of filamentous phage are integral membrane proteins prior to assembly; hence they are ideal for display of bacterial surface and secreted proteins. The use of this technology at the scale of microbial community has potential to identify host-interacting proteins of uncultivable or low-represented community members. Recent applications of Ff filamentous phage extend into protein evolution, synthetic biology and nanotechnology. In many applications, phage serves as a monodisperse long-aspect nano-scaffold of well-defined shape. Chemical or chenetic modifications of this scaffold are used to introduce the necessary functionalities, such as fluorescent labels, ligands that target specific proteins, or peptides that promote formation of inorganic or organic nanostructures. We anticipate that the future holds development of new strategies for particle assembly, site-specific multi-functional modifications and improvement of existing modification strategies. These improvements will render the production of filamentous-phage-templated materials safe and affordable, allowing their applications outside of the laboratory.

Roles Of Regulatory Rnas In Bacterial Pathogens

DOWNLOAD
Author : Olga Soutourina
language : en
Publisher: Frontiers Media SA
Release Date : 2022-07-07

Roles Of Regulatory Rnas In Bacterial Pathogens written by Olga Soutourina and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-07-07 with Science categories.

Yersinia Pestis Retrospective And Perspective

DOWNLOAD
Author : Ruifu Yang
language : en
Publisher: Springer
Release Date : 2016-10-08

Yersinia Pestis Retrospective And Perspective written by Ruifu Yang and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-10-08 with Medical categories.

This book addresses nearly every aspect of Y. pestis, approaching it from a new perspective. Topics covered include the history, epidemiology, physiology, ecology, genome, evolution, pathogenesis, host-pathogen interaction, big-data-driven research, vaccines, clinical aspects and future research trends. For centuries, scientists have sought to determine where Y. pestis, the most well-known bacterium and one that has caused a number of high-mortality epidemics throughout human history, comes from, what it is and how it causes the disease. This book works to answer these questions with the help of cutting-edge research results. It not only describes the history of plagues, but also stresses plagues’ effects on human civilization and explores the interaction of Y. pestis with hosts, vectors and the environment to reveal the evolution and pathogenesis. The book offers a valuable guide for researchers and graduate students studying Y. pestis, and will also benefit researchers from other fields, such as infectious diseases, other pathogens and system biology, sharing key insights into bacterial pathogen studies.