The Plains Of Norwich
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The Plains Of Norwich
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Author : Richard Lane
language : en
Publisher:
Release Date : 1999
The Plains Of Norwich written by Richard Lane and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with Norwich (England) categories.
The Rings Of Saturn
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Author : W.G. Sebald
language : en
Publisher: Random House
Release Date : 2013-11-30
The Rings Of Saturn written by W.G. Sebald and has been published by Random House this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-30 with Travel categories.
‘Sebald is the Joyce of the 21st Century’ The Times What begins as the record of W. G. Sebald’s own journey on foot through coastal East Anglia, from Lowestoft to Bungay, becomes the conductor of evocations of people and cultures past and present. From Chateaubriand, Thomas Browne, Swinburne and Conrad, to fishing fleets, skulls and silkworms, the result is an intricately patterned and haunting book on the transience of all things human. ‘A novel of ideas with a difference: it is nothing but ideas... Formally dexterous, fearlessly written (why shouldn't an essay be a novel?), and unremittingly arcane; by the end I was in tears’ Teju Cole, Guardian
History Of Windsor County Vermont
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Author : Lewis Cass Aldrich
language : en
Publisher:
Release Date : 1891
History Of Windsor County Vermont written by Lewis Cass Aldrich and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1891 with Vermont categories.
Cytotoxic Payloads For Antibodydrug Conjugates
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Author : David E Thurston
language : en
Publisher: Royal Society of Chemistry
Release Date : 2019-07-11
Cytotoxic Payloads For Antibodydrug Conjugates written by David E Thurston and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-11 with Medical categories.
Antibody–drug conjugates (ADCs) represent one of the most promising and exciting areas of anticancer drug discovery. Five ADCs are now approved in the US and EU [i.e., ado-trastuzumab emtansine (KadcylaTM), brentuximab vedotin (AdcetrisTM), inotuzumab ozogamicin (BesponsaTM), gemtuzumab ozogamicin (MylotargTM) and moxetumomab pasudotox-tdfk (Lumoxiti®)] and over 70 others are in various stages of clinical development, with impressive interim results being reported for many. The technology is based on the concept of delivering a cytotoxic payload selectively to cancer cells by attaching it to an antibody targeted to antigens on the cell surfaces. This approach has several advantages including the ability to select patients as likely responders based on the presence of antigen on the surface of their cancer cells and a wider therapeutic index, given that ADC targeting enables a more efficient delivery of cytotoxic agents to cancer cells than can be achieved by conventional chemotherapy, thus minimising systemic toxicity. Although there are many examples of antibodies that have been developed for this purpose, along with numerous linker technologies used to attach the cytotoxic agent to the antibody, there is presently a relatively small number of payload molecules in clinical use. The purpose of this book is to describe the variety of payloads used to date, along with a discussion of their advantages and disadvantages and to provide information on novel payloads at the research stage that may be used clinically in the future.
Connecticut A Guide To Its Roads Lore And People
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Author : Best Books on
language : en
Publisher: Best Books on
Release Date : 1938
Connecticut A Guide To Its Roads Lore And People written by Best Books on and has been published by Best Books on this book supported file pdf, txt, epub, kindle and other format this book has been release on 1938 with categories.
written by workers of the Federal writers' project of the Works progress administration for the state of Connecticut; sponsored by Wilbur L. Cross ...
Bread And Ale For The Brethren
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Author : Philip Slavin
language : en
Publisher: Univ of Hertfordshire Press
Release Date : 2012-04
Bread And Ale For The Brethren written by Philip Slavin and has been published by Univ of Hertfordshire Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-04 with Cooking categories.
Despite increased commercialization and an efficient network of local markets in 1300s Europeas well as significant costs and risks associated with the production, transportation, and storage of foodsome landed lords, monasteries, and convents continued to rely on the produce of their own estates. This detailed study sets out to account for the puzzling situation, covering the period between 1260 and 1536, with an in-depth analysis of the changing patterns and fortunes of the provisioning of Norwich Cathedral Priory. As it examines the entire process of food delivery from field to table, the record explores the question of food security within the context of the various crises in the 14th century, and also illustrates the aftereffects of the Black Death. Although providing unparalleled insight into the Priory, the book also serves as an important resource on understanding the Late Middle Ages economy of England and society during a time of upheaval."
Plainsong
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Author : Kent Haruf
language : en
Publisher: Vintage
Release Date : 2001-04-03
Plainsong written by Kent Haruf and has been published by Vintage this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-04-03 with Fiction categories.
National Book Award Finalist A heartstrong story of family and romance, tribulation and tenacity, set on the High Plains east of Denver. In the small town of Holt, Colorado, a high school teacher is confronted with raising his two boys alone after their mother retreats first to the bedroom, then altogether. A teenage girl—her father long since disappeared, her mother unwilling to have her in the house—is pregnant, alone herself, with nowhere to go. And out in the country, two brothers, elderly bachelors, work the family homestead, the only world they've ever known. From these unsettled lives emerges a vision of life, and of the town and landscape that bind them together—their fates somehow overcoming the powerful circumstances of place and station, their confusion, curiosity, dignity and humor intact and resonant. As the milieu widens to embrace fully four generations, Kent Haruf displays an emotional and aesthetic authority to rival the past masters of a classic American tradition.
Multilingualism And Pluricentricity
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Author : John Hajek
language : en
Publisher: Walter de Gruyter GmbH & Co KG
Release Date : 2023-11-20
Multilingualism And Pluricentricity written by John Hajek and has been published by Walter de Gruyter GmbH & Co KG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-20 with Language Arts & Disciplines categories.
This volume explores linguistic diversity and complexity in different urban contexts, many of which have never been subject to significant sociolinguistic inquiry. A novel mixture of cities of varying size from around the world is studied, from megacities to smaller cities on the national periphery. All chapters discuss either the multilingualism or the pluricentric aspect of the linguistic diversity in urban areas, most focussing on one urban centre. The book showcases multiple approaches ranging from a quantitative investigation based partly on census data, to qualitative studies flowing, for example, from extensive ethnographic work or discourse analysis. The diverse theoretical backgrounds and methodological approaches in the individual chapters are complemented by two chapters outlining the current trends and debates in the sociolinguistic research on urban multilingualism and pluricentricity and suggesting some possible directions for future investigations in this field.The book thus provides a broad overview of sociolinguistic research of multilingual places and pluricentric languages.
The Master Of Game
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Author : Edward of Norwich
language : en
Publisher: University of Pennsylvania Press
Release Date : 2013-10-09
The Master Of Game written by Edward of Norwich and has been published by University of Pennsylvania Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-09 with History categories.
The Master of Game is the oldest and most important work on the chase in the English language. Based primarily on Gaston de Foix's Livre de chasse, originally composed in 1387, The Master of Game was written by Edward of Norwich at his leisure between 1406 and 1413, mostly while being held prisoner for having treasonous designs against his cousin, Henry IV. While much of the book is almost an exact translation of de Foix, Edward added five chapters of his own to form the major source for our knowledge of the medieval hunt. The book begins with a description of the nature of popular quarry, such as the hare, deer, and badger, including their behavior, characteristics, and even smells, and then moves to a discussion of various hunting dog breeds and how to train them. The medieval chase was a ritual event, so the book continues with an explanation of the various rules and techniques for a successful hunt, including how food was to be distributed among the hunters, the support persons, and the dogs. Weapons and traps of choice are also described, as well as the different horn calls used for communication. The Master of Game is a unique text for naturalists, hunters, and persons interested in social history. Although hunting is nowadays far removed from most people's experience, it was of major interest in the time of Edward of Norwich for ritual, sport, and, of course, food. Some knowledge of the chase was essential for all persons of medieval times. This edition, the first paperback ever of the original version edited in 1909, includes a hearty foreword by Theodore Roosevelt, who adds some important contextual information about the chase and draws on his own vast hunting experience. A delight to read, even for those who are not keen on the sport, The Master of Game has, as one review exclaimed," all Chaucer's freshness, love of the open sky and fragrant woodland."
A History Of Lodge No 61 F And A M Wilkesbarr Pa
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Author : Oscar Jewell Harvey
language : en
Publisher:
Release Date : 1897
A History Of Lodge No 61 F And A M Wilkesbarr Pa written by Oscar Jewell Harvey and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1897 with categories.