The Pneumococcus
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Life With The Pneumococcus
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Author : Robert Austrian
language : en
Publisher: University of Pennsylvania Press
Release Date : 2016-11-11
Life With The Pneumococcus written by Robert Austrian and has been published by University of Pennsylvania Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-11-11 with Medical categories.
Because of the high fatality rate of untreated pneumococcal pneumonia, both the disease and its principal cause, the pneumococcus, were objects of intense scrutiny by physicians and bacteriologists during the last two decades of the nineteenth century and the first half of the twentieth. As a result, scientists learned much of the fundamental importance to microbiology, immunology, and genetics while developing the pneumococcal vaccine.
The Pneumococcus
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Author : Elaine I. Tuomanen
language : en
Publisher:
Release Date : 2004
The Pneumococcus written by Elaine I. Tuomanen and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Medical categories.
A state-of-the-art examination of research in this field and the impact of this gram-positive pathogen on human disease. * Provides coverage of topics in basic microbiology such as details of DNA transformation, molecular and medical epidemiology, the molecular basis of invasive disease, and various interactions with host defenses. * Presents important historical information on the field of pneumococcal research and suggests strategies for future investigation. * Serves as a valuable source of information for graduate and medical school students, infectious disease specialists, and field researchers in the pathogenesis of gram-positive bacteria.
The Pneumococcus And Pneumococcal Affections
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Author : Louis Cotoni
language : en
Publisher:
Release Date : 1924
The Pneumococcus And Pneumococcal Affections written by Louis Cotoni and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1924 with Pneumococcal Infections categories.
The Pneumococcus And The Pneumococcal Vaccine
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Author : Paul G. Quie
language : en
Publisher:
Release Date : 1982
The Pneumococcus And The Pneumococcal Vaccine written by Paul G. Quie and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1982 with Medical categories.
Streptococcus Pneumoniae
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Author : Jeremy Brown
language : en
Publisher: Academic Press
Release Date : 2015-05-08
Streptococcus Pneumoniae written by Jeremy Brown and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-05-08 with Science categories.
Streptococcus Pneumoniae: Molecular Mechanisms of Host-Pathogen Interactions provides a comprehensive overview of our existing knowledge on Streptococcus pneumoniae antibiotic resistance, dissemination, and pathogenesis, including immunology. It presents a state-of-the-art overview of the implications of existing data, along with the areas of research that are important for future insights into the molecular mechanisms of pneumococcal infections and how to combat these infections. Users will find a timely update on the topic, as the dramatic increase in antibiotic resistance pneumoniae cases and limitations of the currently available pneumoniae vaccines are creating new concerns on these gram-positive bacteria that are endowed with a high virulence potential, and are the most common etiologic agent of respiratory and life-threatening invasive diseases. Provides an updated overview of our existing knowledge on Streptococcus pneumoniae antibiotic resistance, dissemination, and pathogenesis, including immunology Helps strengthen interdisciplinary networking and the focus of scientific resources by targeting epidemiology, vaccines, genetics, antibiotic resistance, clonal dissemination, Streptococcus pneumoniae biology, functional genomics, inflammasome, biomarkers, and more Multi-authored by leaders in the field who present a state-of-the-art overview of what the implications are of existing data, and the areas of research that are important for future insights into the molecular mechanisms of pneumococcal infections Supports combinatory networking in order to find new solutions in clinical therapies Reflects the most topical pneumococcal research trends
Molecular Pathogenesis Of Pneumococus
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Author : Jorge Eugenio Vidal
language : en
Publisher: Frontiers Media SA
Release Date : 2023-05-11
Molecular Pathogenesis Of Pneumococus written by Jorge Eugenio Vidal and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-05-11 with Science categories.
Streptococcus pneumoniae (the pneumococcus) is a commensal of the human nasopharynx during childhood, but also causes a variety of infections, such as otitis media (OM), pneumonia, bacteremia, and meningitis, mainly affecting infants, the elderly and immunocompromised patients. Pneumococcal pneumonia alone produces more child deaths, every year, than any other bacterial disease worldwide. To date, more than 90 distinct capsular serotypes have been identified. Current pneumococcal conjugate vaccines (PCV) protect against 7, 10 or 13 different pneumococcal types. These vaccines have decreased the burden of pneumococcal disease produced by vaccine types but provide poor protection against non-vaccine serotypes. Additionally, the increasing prevalence of multi-drug resistant S. pneumoniae strains results in more challenge for treatment of pneumococcal infections. Therefore, it is imperative to continue investigating the molecular pathogenesis of the pneumococcus. There are currently a variety of key virulence determinants known to be involved in pathogenesis of pneumococcal disease. Virulence factors and host immune defense are major players during pathogen - host interactions. Some metabolic pathways have also been shown to play a role in pneumococcal pathogenesis. These metabolic pathways include proteins involved in copper efflux, arginine metabolism, and zinc homeostasis. From the human host side, new host factors have been found to play essential roles in clearance of S. pneumoniae during infection, such as microRNA-155. Moreover, biofilm-like structures may alter both pneumococcal phenotypes and the host immunity during nasopharyngeal carriage and/or during disease. Understanding the interaction between pneumococcus and its human host is a key to combat pneumococcal infections. It has been well known for several years that pneumococcal pneumonia is worsened during poly-microbial infection. During the past few years, rapid progress has been made in this area. For example, it was recently shown that influenza A virus increases pneumococcal nasal colonization and it is a risk factor for pneumococcal pneumonia. Other important respiratory viruses and bacterial pathogens, such as Moraxella catarrhalis and Haemophilus influenzae, appear to increase the risk of pneumococcal colonization and disease. A better understanding of the molecular mechanism leading to these pathogenic synergisms will provide a fundamental basis for prevention and treatment of secondary pneumococcal infection. The elderly population is generally more susceptible to pneumococcal infections. In addition to their declined immunity, alteration of the microbiome seen in the elderly may play a role for the susceptibility of infection. Research with the elderly or using elderly animal infection models will largely enhance our knowledge and significantly reduce the morbidity and mortality caused by pneumococcal infections.
Experimental Pneumonia Produced By The Pneumococcus And Streptococcus
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Author : Grace Bernice Rhodes
language : en
Publisher:
Release Date : 1920
Experimental Pneumonia Produced By The Pneumococcus And Streptococcus written by Grace Bernice Rhodes and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1920 with categories.
The Pneumococcus And Pneumococcal Infections
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Author : L. Cotoni
language : en
Publisher:
Release Date : 1924
The Pneumococcus And Pneumococcal Infections written by L. Cotoni and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1924 with Pneumoccocal infections categories.
The Relationship Of The Pneumococcus To Acute Infections Of The Upper Respiratory Tract In Man
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Author : John Everett Gordon
language : en
Publisher:
Release Date : 1921
The Relationship Of The Pneumococcus To Acute Infections Of The Upper Respiratory Tract In Man written by John Everett Gordon and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1921 with Cold (Disease) categories.
Streptococcus Pneumoniae
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Author : Federico Iovino
language : en
Publisher: Humana Press
Release Date : 2019-04-01
Streptococcus Pneumoniae written by Federico Iovino and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-01 with Medical categories.
This volume looks at the newest methods, materials, equipment, and technologies developed to study the cell biology of the pneumococcus. The chapters, which cover a wide range of topics, are organized into six parts: Part one discusses the cultivation of Streptococcus pneumoniae in vitro; Part Two talks about the microscopy techniques used to study the biology of Streptococcus pneumoniae and pneumococcal interactions with the host; Parts Three and Four describe the genetics, proteome, and proteomics of Streptococcus pneumoniae; Part Five explains in vitro and in vivo models of Streptococcus pneumoniae-host interactions; and Part Six looks at the factors of public health, epidemiology, and biostatistics. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and authoritative, Streptococcus pneumoniae: Methods and Protocols is a valuable resource for both novice and expert researchers who want to expand their studies into new areas and new systems in this continuously evolving field.