The Potential Of Plants As A Source Of Antimalarial Agents
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The Potential Of Plants As A Source Of Antimalarial Agents
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Author : Geoffrey Rukunga
language : en
Publisher:
Release Date : 2006
The Potential Of Plants As A Source Of Antimalarial Agents written by Geoffrey Rukunga and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Antimalarials categories.
Medicinal Plants And Malaria
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Author : Woon-Chien Teng
language : en
Publisher: CRC Press
Release Date : 2016-01-06
Medicinal Plants And Malaria written by Woon-Chien Teng and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-01-06 with Health & Fitness categories.
Malaria is a potentially life-threatening disease that affects millions worldwide, especially in Sub-Saharan Africa. The recent emergence and spread of multidrug resistance in parts of Southeast Asia prompts the urgent need for novel and effective therapy against the disease. Medicinal Plants and Malaria: Applications, Trends, and Prospects highlig
Traditional Medicinal Plants And Malaria
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Author : Merlin Willcox
language : en
Publisher: CRC Press
Release Date : 2004-06-28
Traditional Medicinal Plants And Malaria written by Merlin Willcox and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-06-28 with Health & Fitness categories.
Malaria is an increasing worldwide threat, with more than three hundred million infections and one million deaths every year. The worlds poorest are the worst affected, and many treat themselves with traditional herbal medicines. These are often more available and affordable, and sometimes are perceived as more effective than conventional antimala
Antimalarial Natural Products
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Author : A. Douglas Kinghorn
language : en
Publisher: Springer Nature
Release Date : 2022-01-02
Antimalarial Natural Products written by A. Douglas Kinghorn and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-02 with Science categories.
This volume begins with a short history of malaria and follows with a summary of its biology. It then traces the fascinating history of the discovery of quinine for malaria treatment, and then describes quinine’s biosynthesis, its mechanism of action, and its clinical use, concluding with a discussion of synthetic antimalarial agents based on quinine’s structure. It also covers the discovery of artemisinin and its development as the source of the most effective current antimalarial drug, including summaries of its synthesis and biosynthesis, its mechanism of action, and its clinical use and resistance. A short discussion of other clinically used antimalarial natural products leads to a detailed treatment of additional natural products with significant antiplasmodial activity, classified by compound type. Although the search for new antimalarial natural products from Nature’s combinatorial library is challenging, it is very likely to yield new antimalarial drugs. This book thus ends by identifying ten natural products with development potential as clinical antimalarial agents.
Current Topics In Malaria
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Author : Alfonso J. Rodriguez-Morales
language : en
Publisher:
Release Date : 2016-11-30
Current Topics In Malaria written by Alfonso J. Rodriguez-Morales and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-11-30 with categories.
Antimalarial Medicinal Plants
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Author : Azamal Husen
language : en
Publisher: CRC Press
Release Date : 2024-04-22
Antimalarial Medicinal Plants written by Azamal Husen and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-04-22 with Science categories.
Malaria continues to affect a large population of the world, especially in third world countries. The spread of drug-resistant parasites demonstrates the need for antimalarial agents with various modes of action. The search for remedies derived from medicinal plants for the treatment of malaria is reliant on accurate ethnobotanical and ethnopharmacological information obtained from traditional medical practitioners. Antimalarial Medicinal Plants provides information on bioactive compounds and therapeutic potentials of several antimalarial plant species found around the globe. This book evaluates these plant species with respect to their biology, diversity, distribution, and pharmacological values. A volume in the Exploring Medicinal Plants series, this book highlights trends, technologies, processes, and services important to and necessary for efficient production, use, and understanding of medicinal qualities of antimalarial plants. It critically examines claims made by traditional medical practitioners with scientific validations for safe herbal drug formulation. It is a reference work for researchers of herbal medicine, traditional healers, pharmacists, and students associated with plant sciences and economic botany.
Plant Derived Bioactives
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Author : Mallappa Kumara Swamy
language : en
Publisher: Springer Nature
Release Date : 2020-05-11
Plant Derived Bioactives written by Mallappa Kumara Swamy and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-05-11 with Science categories.
Plants produce a vast number of bioactive compounds with different chemical scaffolds, which modulate a diverse range of molecular targets and are used as drugs for treating numerous diseases. Most present-day medicines are derived either from plant compounds or their derivatives, and plant compounds continue to offer limitless reserves for the discovery of new medicines. While different classes of plant compounds, like phenolics, flavonoids, saponins and alkaloids, and their potential pharmacological applications are currently being explored, their curative mechanisms are yet to be understood in detail. This book is divided into 2 volumes and offers detailed information on plant-derived bioactive compounds, including recent research findings. Volume 1, Plant-derived Bioactives: Chemistry and Mode of Action, discusses the chemistry of highly valued plant bioactive compounds and their mode of actions at the molecular level. Volume 2, Plant-derived Bioactives: Production, Properties and Therapeutic Applications, explores the sources, biosynthesis, production, biological properties and therapeutic applications of plant bioactives. Given their scope, these books are valuable resources for members of the scientific community wishing to further explore various medicinal plants and the therapeutic applications of their bioactive compounds. They appeal to scholars, teachers and scientists involved in plant product research, and facilitate the development of innovative new drugs.
Artemisia Annua Pharmacology And Biotechnology
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Author : Tariq Aftab
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-26
Artemisia Annua Pharmacology And Biotechnology written by Tariq Aftab and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-26 with Science categories.
Artemisinin, a sesquiterpene lactone originally extracted from the medicinal plant Artemisia annua L., is an effective antimalarial agent, particularly for multi-drug resistant and cerebral malaria. However, the concentration of artemisinin in the plant is very low. Because the chemical synthesis of artemisinin is complicated and not economically feasible in view of the poor yield of the drug, the intact plant remains the only viable source of artemisinin production. Therefore, it is necessary to increase the concentration of artemisinin in A. annua to reduce the cost of artemisinin based antimalarial drugs. Plant scientists have focused their efforts on A. annua for a higher artemisinin crop yield. With the present volume, we are bringing together the research which is being done on this plant throughout the world and future possibilities for scientists and researchers who want to work on it.
Saving Lives Buying Time
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2004-09-09
Saving Lives Buying Time written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-09-09 with Medical categories.
For more than 50 years, low-cost antimalarial drugs silently saved millions of lives and cured billions of debilitating infections. Today, however, these drugs no longer work against the deadliest form of malaria that exists throughout the world. Malaria deaths in sub-Saharan Africaâ€"currently just over one million per yearâ€"are rising because of increased resistance to the old, inexpensive drugs. Although effective new drugs called "artemisinins" are available, they are unaffordable for the majority of the affected population, even at a cost of one dollar per course. Saving Lives, Buying Time: Economics of Malaria Drugs in an Age of Resistance examines the history of malaria treatments, provides an overview of the current drug crisis, and offers recommendations on maximizing access to and effectiveness of antimalarial drugs. The book finds that most people in endemic countries will not have access to currently effective combination treatments, which should include an artemisinin, without financing from the global community. Without funding for effective treatment, malaria mortality could double over the next 10 to 20 years and transmission will intensify.
Herbal Drugs Ethnomedicine To Modern Medicine
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Author : Kishan Gopal Ramawat
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-11-25
Herbal Drugs Ethnomedicine To Modern Medicine written by Kishan Gopal Ramawat and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-11-25 with Science categories.
Considerable progress has been made in our healthcare system, in particular with respect to sensitive diagnostic tools, reagents and very effective and precise drugs. On the other hand, high-throughput screening technology can screen vast numbers of compounds against an array of targets in a very short time, and leads thus - tained can be further explored. In developing countries, the exploding population exerts pressure not only on natural resources but also on the human population - self, whose members strive to become successful and advance in society. This leads to increased blood pressure, anxiety, obesity-associated lipid disorders, cardiov- cular diseases and diabetes. Most of these diseases result in disturbed family life, including sexual behaviour. Despite technological developments, herbal drugs still occupy a preferential place in a majority of the population in the Third World and terminal patients in the West. Herbal drugs, in addition to being cost effective and easily accessible, have been used since time immemorial and have passed the test of time without having any side effects. The multitarget effects of herbs (holistic approaches) are the fun- mental basis of their utilization. This approach is already used in traditional systems of medicine like Ayurveda, which has become more popular in the West in recent years. However, the integration of modern science with traditional uses of herbal drugs is of the utmost importance if ones wishes to use ancient knowledge for the betterment of humanity.