The Practise Of Medicinal Chemistry
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The Practice Of Medicinal Chemistry
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Author : Camille Georges Wermuth
language : en
Publisher: Elsevier
Release Date : 2015-07-01
The Practice Of Medicinal Chemistry written by Camille Georges Wermuth and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-07-01 with Science categories.
The Practice of Medicinal Chemistry, Fourth Edition provides a practical and comprehensive overview of the daily issues facing pharmaceutical researchers and chemists. In addition to its thorough treatment of basic medicinal chemistry principles, this updated edition has been revised to provide new and expanded coverage of the latest technologies and approaches in drug discovery. With topics like high content screening, scoring, docking, binding free energy calculations, polypharmacology, QSAR, chemical collections and databases, and much more, this book is the go-to reference for all academic and pharmaceutical researchers who need a complete understanding of medicinal chemistry and its application to drug discovery and development. Includes updated and expanded material on systems biology, chemogenomics, computer-aided drug design, and other important recent advances in the field Incorporates extensive color figures, case studies, and practical examples to help users gain a further understanding of key concepts Provides high-quality content in a comprehensive manner, including contributions from international chapter authors to illustrate the global nature of medicinal chemistry and drug development research An image bank is available for instructors at www.textbooks.elsevier.com
The Practice Of Medicinal Chemistry
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Author : Camille Georges Wermuth
language : en
Publisher: Academic Press
Release Date : 2011-05-02
The Practice Of Medicinal Chemistry written by Camille Georges Wermuth and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-05-02 with Medical categories.
The Practice of Medicinal Chemistry fills a gap in the list of available medicinal chemistry literature. It is a single-volume source on the practical aspects of medicinal chemistry. Considered ""the Bible"" by medicinal chemists, the book emphasizes the methods that chemists use to conduct their research and design new drug entities. It serves as a practical handbook about the drug discovery process, from conception of the molecules to drug production. The first part of the book covers the background of the subject matter, which includes the definition and history of medicinal chemistry, the measurement of biological activities, and the main phases of drug activity. The second part of the book presents the road to discovering a new lead compound and creating a working hypothesis. The main parts of the book discuss the optimization of the lead compound in terms of potency, selectivity, and safety. The Practice of Medicinal Chemistry can be considered a ""first-read"" or ""bedside book"" for readers who are embarking on a career in medicinal chemistry. NEW TO THIS EDITION: * Focus on chemoinformatics and drug discovery * Enhanced pedagogical features* New chapters including: - Drug absorption and transport - Multi-target drugs* Updates on hot new areas: NEW! Drug discovery and the latest techniques NEW! How potential drugs can move through the drug discovery/ development phases more quickly NEW! Chemoinformatics
The Handbook Of Medicinal Chemistry
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Author : Andrew Davis
language : en
Publisher: Royal Society of Chemistry
Release Date : 2015-07-07
The Handbook Of Medicinal Chemistry written by Andrew Davis and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-07-07 with Science categories.
Drug discovery is a constantly developing and expanding area of research. Developed to provide a comprehensive guide, the Handbook of Medicinal Chemistry covers the past, present and future of the entire drug development process. Highlighting the recent successes and failures in drug discovery, the book helps readers to understand the factors governing modern drug discovery from the initial concept through to a marketed medicine. With chapters covering a wide range of topics from drug discovery processes and optimization, development of synthetic routes, pharmaceutical properties and computational biology, the handbook aims to enable medicinal chemists to apply their academic understanding to every aspect of drug discovery. Each chapter includes expert advice to not only provide a rigorous understanding of the principles being discussed, but to provide useful hints and tips gained from within the pharmaceutical industry. This expertise, combined with project case studies, highlighting and discussing all areas of successful projects, make this an essential handbook for all those involved in pharmaceutical development.
Medicinal Chemistry
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Author : Frank D. King
language : en
Publisher:
Release Date : 1994
Medicinal Chemistry written by Frank D. King and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with Medical categories.
An introduction to the subject, aimed primarily at synthetic chemists, which explains how to identify a drug candidate from an initial lead compound that possesses the properties required for successful development. The main aim of the text is to address the quality of interpretations.
The Practice Of Medicinal Chemistry 3 E
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Author : Wermuth
language : en
Publisher:
Release Date : 2009-01-01
The Practice Of Medicinal Chemistry 3 E written by Wermuth and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-01-01 with categories.
The Practice Of Medicinal Chemistry
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Author : Camille Georges Wermuth
language : en
Publisher: Elsevier
Release Date : 2003-06-11
The Practice Of Medicinal Chemistry written by Camille Georges Wermuth and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-06-11 with Science categories.
The Practice of Medicinal Chemistry, 2E, is a single-volume source on the practical aspects of medicinal chemistry. The successful first edition was nicknamed "The Bible" by medicinal chemists, and the second edition has been updated, expanded and refocused to reflect developments over the last decade. Emphasis is put on how medicinal chemists conduct their search for and design of new drug entities. In contrast to competing books, it focuses on the chemistry rather than pharmacological concepts or descriptions of the various therapeutic classes of drugs. Most medicinal chemists working in the pharmaceutical industry are organic synthetic chemists who must acquire a strong knowledge of medicinal chemistry as they enter the industry. This book aims to be their practical handbook - a complete guide to the drug discovery process. * The only book available dealing with the practical aspects of medicinal chemistry * Serves as a complete guide to the drug discovery process, from conception of the molecules to drug production * Updated chapters devoted to the discovery of new lead compounds, including combinatorial chemistry
Experimental Organic Medicinal Chemistry
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Author : N. Swathi
language : en
Publisher:
Release Date : 2016-09-27
Experimental Organic Medicinal Chemistry written by N. Swathi and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-27 with Science categories.
The modern medicinal chemistry utilizes several novel drug discovery tools to identify the drug-like molecules (lead) and to convert them into therapeutically potential molecules. The advanced and adequate practice in synthetic medicinal chemistry is essential for pharmacy graduates (B. Pharmacy and M. Pharmacy) to receive recognition in academia and industry sectors. This book titled Experimental Organic and Medicinal Chemistry-Principles & Practice consists of several topics covering both theory and practical concepts. The material spreads into synthetic and analytical approaches. The synthetic approach includes synthesis of drugs and drug intermediates and green synthetic strategy. The analytical approach deals with estimations of drugs, qualitative analysis of inorganic, organic and natural products, isolation and determination of active principles from natural sources. In addition, safety measurements, general laboratory practices, preparation of a few solutions and reagents are included as a ready reference. This book is a good companion for students of B. Pharmacy and a source book for M. Pharmacy (Pharmaceutical chemistry, Medicinal Chemistry) and other Pharmaceutical and medicinal chemistry disciplines. Salient features of this book are Systematic descriptions in simple language. Neat and self explanatory chemical reaction mechanisms. The role of reagents, alternative reagents and hazards associated are highlighted. Pharmaceutical relevance of chemical reactions are described. Limit tests, qualitative analysis of inorganic, natural and synthetic organic compounds are described in a lucid manner. Estimations of natural and organic-medicinal compounds along with isolation of active principles are discussed.
Medicinal Chemistry For Practitioners
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Author : Jie Jack Li
language : en
Publisher: John Wiley & Sons
Release Date : 2020-06-29
Medicinal Chemistry For Practitioners written by Jie Jack Li and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-29 with Medical categories.
Presenting both a panoramic introduction to the essential disciplines of drug discovery for novice medicinal chemists as well as a useful reference for veteran drug hunters, this book summarizes the state-of-the-art of medicinal chemistry. It covers key drug targets including enzymes, receptors, and ion channels, and hit and lead discovery. The book hen surveys a drug's pharmacokinetics and toxicity, with a solid chapter covering fundamental bioisosteres as a guide to structure-activity relationship investigations.
The Practise Of Medicinal Chemistry
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Author : Camille G. Wermuth
language : es
Publisher:
Release Date : 1996
The Practise Of Medicinal Chemistry written by Camille G. Wermuth and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with categories.
Handbook Of Research On Medicinal Chemistry
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Author : Debarshi Kar Mahapatra
language : en
Publisher: Taylor & Francis
Release Date : 2017-11-20
Handbook Of Research On Medicinal Chemistry written by Debarshi Kar Mahapatra and has been published by Taylor & Francis this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-20 with Medical categories.
This valuable new book, Handbook of Research on Medicinal Chemistry: Innovations and Methodologies, presents some of the latest advancements in the various fields of combinatorial chemistry, drug discovery, biochemical aspects, pharmacology of medicinal agents, current practical problems, and nutraceuticals. The editors keep the drug molecule as the central component of the volume and aim to explain the associated features essential to exhibiting pharmacological activity. With a unique combination of chapters in biology, clinical aspects, biochemistry, synthetic chemistry, medicine and technology, the volume provides broad exposure to the essential aspect of pharmaceuticals. The volume many important aspects of medicinal chemistry, including techniques in drug discovery pharmacological aspects of natural products chemical mediators: druggable targets advances in medicinal chemistry The field of medicinal chemistry is growing at an unprecedented pace, and this volume takes an interdisciplinary approach, covering a range of new research and new practices in the field. The volume takes into account the latest therapeutic guidelines put forward by the World Health Organization and the U.S Food and Drug Administration.. Topics include: drug design drug discovery natural products and supplements and nutraceuticals pharmaceutical approaches to sexual dysfunction drug resistance parasites new natural compounds and identification of new targets stereochemistry aspects in medicinal chemistry common drug interactions in daily practices Handbook of Research on Medicinal Chemistry: Innovations and Methodologies will be a valuable addition to the bookshelves of pharmaceutical scientists and faculty as well as for industry professionals.