The Problem Of Excitability
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The Problem Of Excitability
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Author : B. Khodorov
language : en
Publisher:
Release Date : 2011-11-08
The Problem Of Excitability written by B. Khodorov and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-11-08 with categories.
The Problem Of Excitability
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Author : B. Khodorov
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
The Problem Of Excitability written by B. Khodorov and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
The Russian edition of this book appeared in 1969 and im mediately gained widespread recognition as a reference work for research workers interested in the physiology, biophysics, and pharmacology of excitable tissues. There are several reasons for the book's success. It deals with a key problem in biology which has recently been the subject of very intensive study and it is of great interest to a wide scientific audience. Not only the fundamentals of the modern membrane theory of biopotentials, but also the vast factual material collected in the last decades by the study of the biophysical and pharmacological properties of the ionic permeability pores of the cell membrane, are described in the book in an authoritative yet readable form. Special attention is paid in the book to the systematic analysis of the consequences of the Hodgkin-Huxley mathematical theory of the nervous impulse for the problem of excitability. The relationship between the various parameters of excitability (threshold potential, threshold current, useful time), accommodation, and the action potential on the one hand, and the constants of ionic permeability of the nerve fiber membrane, on the other hand, is subjected to detailed examination in this context. To do this, the author has made extensive use not only of experimental results obtained on isolated fibers (especially single nodes of Ran vier), but also the results of his own investigations on mathematical models of excitable membranes.
Dynamical Systems In Neuroscience
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Author : Eugene M. Izhikevich
language : en
Publisher: MIT Press
Release Date : 2010-01-22
Dynamical Systems In Neuroscience written by Eugene M. Izhikevich and has been published by MIT Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-01-22 with Medical categories.
Explains the relationship of electrophysiology, nonlinear dynamics, and the computational properties of neurons, with each concept presented in terms of both neuroscience and mathematics and illustrated using geometrical intuition. In order to model neuronal behavior or to interpret the results of modeling studies, neuroscientists must call upon methods of nonlinear dynamics. This book offers an introduction to nonlinear dynamical systems theory for researchers and graduate students in neuroscience. It also provides an overview of neuroscience for mathematicians who want to learn the basic facts of electrophysiology. Dynamical Systems in Neuroscience presents a systematic study of the relationship of electrophysiology, nonlinear dynamics, and computational properties of neurons. It emphasizes that information processing in the brain depends not only on the electrophysiological properties of neurons but also on their dynamical properties. The book introduces dynamical systems, starting with one- and two-dimensional Hodgkin-Huxley-type models and continuing to a description of bursting systems. Each chapter proceeds from the simple to the complex, and provides sample problems at the end. The book explains all necessary mathematical concepts using geometrical intuition; it includes many figures and few equations, making it especially suitable for non-mathematicians. Each concept is presented in terms of both neuroscience and mathematics, providing a link between the two disciplines. Nonlinear dynamical systems theory is at the core of computational neuroscience research, but it is not a standard part of the graduate neuroscience curriculum—or taught by math or physics department in a way that is suitable for students of biology. This book offers neuroscience students and researchers a comprehensive account of concepts and methods increasingly used in computational neuroscience. An additional chapter on synchronization, with more advanced material, can be found at the author's website, www.izhikevich.com.
Structure And Function In Excitable Cells
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Author : T.C. Cheng
language : en
Publisher: Springer
Release Date : 2012-02-12
Structure And Function In Excitable Cells written by T.C. Cheng and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-02-12 with Medical categories.
This book is a collection of up-to-date research reviews dealing with various aspects of the structure and function of excitable cells. Its overall objective is to further the search for a better understanding of the mechanism of excitation on a structural and physicochemical basis. The chapters are written by active investigators from a variety of disciplines, repre senting many different points of view. Their complementary fields of expertise give this book the rare feature of extraordinary breadth. Excitability is a fundamental property of many biological systems. The mechanisms by which nerve impulses are initiated and propagated, and by which rhythmical activities are produced in nerve, muscle, and cardiac cells, can be fully elucidated only when the process of excitation is derived from fundamental principles applied to known structural forms, at both the macroscopic and the molecular level. The problems of excitation are complex, requiring knowledge of many aspects of cells, including their morphology, elec trobiology, chemical physics, and biochemistry.
The Problem Of Determining The Excitation Forces In Vibration Testing
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Author : G. de Vries
language : en
Publisher:
Release Date : 1965
The Problem Of Determining The Excitation Forces In Vibration Testing written by G. de Vries and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1965 with Damping (Mechanics) categories.
Voltage Sensitive Ion Channels
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Author : H. Richard Leuchtag
language : en
Publisher: Springer
Release Date : 2008-01-25
Voltage Sensitive Ion Channels written by H. Richard Leuchtag and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-01-25 with Science categories.
Voltage-sensitive ion channels are macromolecules embedded in the membranes of nerve and muscle fibers of animals. Despite decades of intensive research under the traditional approach of gated structural pores, the relation between the structure of these molecules and their function remains enigmatic. This book examines physically oriented approaches not covered in other ion-channel books, and it develops a new physics-based approach to the problem of molecular excitability.
Cellular Biophysics And Modeling
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Author : Greg Conradi Smith
language : en
Publisher: Cambridge University Press
Release Date : 2019-03-14
Cellular Biophysics And Modeling written by Greg Conradi Smith and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-14 with Mathematics categories.
What every neuroscientist should know about the mathematical modeling of excitable cells, presented at an introductory level.
The Sarcolemma
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Author : International Study Group for Research in Cardiac Metabolism
language : en
Publisher: Baltimore : University Park Press
Release Date : 1976
The Sarcolemma written by International Study Group for Research in Cardiac Metabolism and has been published by Baltimore : University Park Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1976 with Science categories.
The Biophysical Basis Of Excitability
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Author : Hugo Gil Ferreira
language : en
Publisher: Cambridge University Press
Release Date : 1985-10-31
The Biophysical Basis Of Excitability written by Hugo Gil Ferreira and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1985-10-31 with Medical categories.
Defines the basic concepts from biology, mathematics, physics and chemistry that are needed to understand how excitable cells function. Applies them specifically to the study of membrane transport, artificial membranes, signal capturing and analysis in biological systems.
Magnesium In The Central Nervous System
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Author : Robert Vink
language : en
Publisher: University of Adelaide Press
Release Date : 2011
Magnesium In The Central Nervous System written by Robert Vink and has been published by University of Adelaide Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Medical categories.
The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.