The Production Of Antibodies


The Production Of Antibodies
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The Production Of Antibodies


The Production Of Antibodies
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Author : Sir Frank Macfarlane Burnet
language : en
Publisher:
Release Date : 1949

The Production Of Antibodies written by Sir Frank Macfarlane Burnet and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1949 with Science categories.




Monoclonal Antibody Production


Monoclonal Antibody Production
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 1999-05-06

Monoclonal Antibody Production written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-05-06 with Medical categories.


The American Anti-Vivisection Society (AAVS) petitioned the National Institutes of Health (NIH) on April 23, 1997, to prohibit the use of animals in the production of mAb. On September 18, 1997, NIH declined to prohibit the use of mice in mAb production, stating that "the ascites method of mAb production is scientifically appropriate for some research projects and cannot be replaced." On March 26, 1998, AAVS submitted a second petition, stating that "NIH failed to provide valid scientific reasons for not supporting a proposed ban." The office of the NIH director asked the National Research Council to conduct a study of methods of producing mAb. In response to that request, the Research Council appointed the Committee on Methods of Producing Monoclonal Antibodies, to act on behalf of the Institute for Laboratory Animal Research of the Commission on Life Sciences, to conduct the study. The 11 expert members of the committee had extensive experience in biomedical research, laboratory animal medicine, animal welfare, pain research, and patient advocacy (Appendix B). The committee was asked to determine whether there was a scientific necessity for the mouse ascites method; if so, whether the method caused pain or distress; and, if so, what could be done to minimize the pain or distress. The committee was also asked to comment on available in vitro methods; to suggest what acceptable scientific rationale, if any, there was for using the mouse ascites method; and to identify regulatory requirements for the continued use of the mouse ascites method. The committee held an open data-gathering meeting during which its members summarized data bearing on those questions. A 1-day workshop (Appendix A) was attended by 34 participants, 14 of whom made formal presentations. A second meeting was held to finalize the report. The present report was written on the basis of information in the literature and information presented at the meeting and the workshop.



The Production Of Antibodies


The Production Of Antibodies
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Author : Sir Frank Macfarlane Burnet
language : en
Publisher:
Release Date : 1953

The Production Of Antibodies written by Sir Frank Macfarlane Burnet and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1953 with Immunoglobulins categories.




Basic Methods In Antibody Production And Characterization


Basic Methods In Antibody Production And Characterization
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Author : Gary C. Howard
language : en
Publisher: CRC Press
Release Date : 2000-09-21

Basic Methods In Antibody Production And Characterization written by Gary C. Howard and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-09-21 with Medical categories.


Written for researchers and professionals in the fields of biomedical research, immunology, biochemistry, molecular biology, pathology, and biotechnology, Basic Methods in Antibody Production and Characterization uses a cookbook approach to presenting the methods for the production, characterization, and use of antibodies. Antibodies described



Janeway S Immunobiology


Janeway S Immunobiology
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Author : Kenneth Murphy
language : en
Publisher: Garland Science
Release Date : 2010-06-22

Janeway S Immunobiology written by Kenneth Murphy and has been published by Garland Science this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-06-22 with Medical categories.


The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.



A Practical Guide To Monoclonal Antibodies


A Practical Guide To Monoclonal Antibodies
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Author : J. Eryl Liddell
language : en
Publisher: John Wiley & Sons
Release Date : 1991-08-26

A Practical Guide To Monoclonal Antibodies written by J. Eryl Liddell and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991-08-26 with Medical categories.


Includes all of the information required to produce monoclonal antibodies in the laboratory and to prepare them for use in a multitude of given applications. Production procedures are treated in chronological order, beginning with basic tissue culture techniques, immunization strategies and screening test design, followed by production of hybridoma cell lines and basic antibody characterization, purification and labeling. Each chapter contains explanatory text on each step with comparative analysis of methods where appropriate. All necessary experimental protocols are presented in a self-contained format that is easy to follow in the laboratory. Alternative protocols are provided where relevant; for others not included in full, source references are presented. Surveys the current status of human hybridoma production and antibody engineering using molecular biology techniques.



Production Of Antibodies


Production Of Antibodies
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Author : Sir Frank Macfarlane Burnet
language : en
Publisher:
Release Date : 1941

Production Of Antibodies written by Sir Frank Macfarlane Burnet and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1941 with Immunoglobulins categories.




Antibodies


Antibodies
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Author : G. Subramanian
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-07

Antibodies written by G. Subramanian and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-07 with Medical categories.


If the antibody industry is to achieve its full potential in the next decade, the individual technical potentials must be exploited, the limitations must be addressed, and lessons learned must be applied both to current purification methods and to the new technologies that continue to emerge. This book presents an overview of the current advances applied in the manufacture of monoclonal antibody including: -concepts in development of manufacturing strategies, -importance of antibody fragments, -application of chromatography method development, -quality control, -effect of expression on antibody properties, -virus removal and safety, -pharmacokinetics, -regulatory aspects.



Making And Using Antibodies


Making And Using Antibodies
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Author : Gary C. Howard
language : en
Publisher: CRC Press
Release Date : 2006-12-13

Making And Using Antibodies written by Gary C. Howard and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-12-13 with Medical categories.


Antibodies are an indispensable tool in the study of biology and medicine. Making and Using Antibodies: A Practical Handbook presents techniques in a single, comprehensive source for the production and use of antibodies. It enables researchers to immediately access lab-tested, proven protocols. Written and edited by an elite team of scienti



Antibody Production


Antibody Production
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Author : L. E. Glynn
language : en
Publisher:
Release Date : 1981

Antibody Production written by L. E. Glynn and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1981 with Medical categories.


A practical guide to the production of antibodies. Describes the biosynthesis of antibody molecules by B lymphocytes and their progeny, the use of genetic markers in the elucidation of mechanisms of antibody synthesis, and of the generation of antibody diversity. Also deals with anomalies in antibody production which result in immunoglobulinopathies, involving qualitative or quantitative abnormalities, or both, in the immunoglobulins.