The Protein Kinase
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The Protein Kinase
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Author :
language : en
Publisher:
Release Date : 1995
The Protein Kinase written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with Protein kinases categories.
Protein Kinase Functions
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Author : James Woodgett
language : en
Publisher: OUP Oxford
Release Date : 2000-08-24
Protein Kinase Functions written by James Woodgett and has been published by OUP Oxford this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-08-24 with Science categories.
Since the publication of Protein Kinases in 1994 many novel protein kinases have been discovered, but perhaps more importantly there have been dramatic advances in our understanding of the cellular functions of this remarkably diverse class of proteins. Protein Kinase Functions is not just an update of the previous edition but provides a new focus on the context and function of protein kinases, thus reflecting the recent advances in kinase biology. Chapters on genetic approaches to protein kinase functions, the MAP kinase pathway, and cyclin-dependent kinases have been completely updated and new topics covered in depth are: phosphatidylinositol 3-kinase signalling, JAK-STAT signalling, suppression of tyrosine kinases by the SOCS family proteins, the TGFß superfamily, and the involvement of protein kinases in response to DNA damage. Throughout, emphasis is placed not on individual kinases, but on the functional aspects of the whole system and the relationship between processes and molecules. It is the aim of Protein Kinase Functions to enable the reader to assimilate, compare, and integrate the molecular machinery used by cells to co-ordinate and respond to their environments.
The Protein Kinase Factsbook Two Volume Set
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Author : Grahame Hardie
language : en
Publisher: Academic Press
Release Date : 1995-06-19
The Protein Kinase Factsbook Two Volume Set written by Grahame Hardie and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-06-19 with Medical categories.
Volume 1: How do you keep track of basic information on the proteins you work with? Where do you find details of their physicochemical properties, amino acid sequences, gene organization? Are you tired of scanning review articles, primary papers and databases to locate that elusive fact? The Academic Press FactsBook series will satisfy scientists and clinical researchers suffering from information overload. Each volume provides a catalogue of the essential properties of families of molecules. Gene organization, amino acid sequences, physicochemical properties, and biological activity are presented using a common, easy to follow format. Taken together they compile everything you wanted to know about proteins but were too busy to look for. The Protein Kinase FactsBook: Protein - Tyrosine Kinases contains over 65 entries on members of the family from vertebrates, Drosophila, slime moulds and other organisms. Entries provide information on: * Subunit structure and isoforms * Genetics * Sequence database accession numbers * Domain structures * Amino acid sequences * Homologues in other species * Patterns of expression * Physiological substrates and specificity determinants * Assays * Enzyme activators and inhibitors * References Volume 2: How do you keep track of basic information on the proteins you work with? Where do you find details of their physicochemical properties, amino acid sequences, gene organization? Are you tired of scanning review articles, primary papers and databases to locate that elusive fact? The Academic Press FactsBook series will satisfy scientists and clinical researchers suffering from information overload. Each volume provides a catalogue of the essential properties of families of molecules. Gene organization, amino acid sequences, physicochemical properties, and biological activity are presented using a common, easy to follow format. Taken together they compile everything you wanted to know about proteins but were too busy to look for. The Protein Kinase FactsBook: Protein - Tyrosine Kinases contains over 130 entries on members of the family from vertebrates, Drosophila, higher plants, yeasts, nematodes, slime moulds and other organisms. Entries provide information on: * Subunit structure and isoforms * Genetics * Sequence database accession numbers * Domain structures * Amino acid sequences * Homologues in other species * Patterns of expression * Physiological substrates and specificity determinants * Assays * Enzyme activators and inhibitors * References
Protein Kinase Protocols
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Author : Alastair D. Reith
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-02
Protein Kinase Protocols written by Alastair D. Reith and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-02 with Science categories.
As key components of many cell signaling pathways, protein kinases are implicated in a broad variety of diseases, including cancers and neurodegenerative conditions, and offer considerable potential as tractable targets for therapeutic intervention. In Protein Kinase Protocols, a panel of highly skilled laboratory investigators describe both basic and more sophisticated methods for the analysis of kinase-mediated signaling cascades, with emphasis on the identification of proteins according to their interactive relationships and the analysis of their functional properties. Described in step-by-step detail, these readily reproducible techniques offer novices quick access to a complicated field, and provide more experienced investigators many novel time-saving ploys. Emphasis is given to the critical technical steps that are often omitted from methods published in the primary literature. There are also tips on potential pitfalls and copious notes on how to adjust the protocols to work in related systems. Broad in its range of techniques and thoroughly detailed to help ensure experimental success, Protein Kinase Protocols offers both novice and experienced investigators powerful tools for understanding the functional roles of specific protein kinases within signaling cascades and for identification and evaluation of novel therapeutic targets.
Protein Kinase Factsbook
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Author : D. Grahame Hardie
language : en
Publisher:
Release Date : 1995
Protein Kinase Factsbook written by D. Grahame Hardie and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with Protein kinases categories.
How do you keep track of basic information on the proteins you work with? Where do you find details of their physicochemical properties, amino acid sequences, gene organization? Are you tired of scanning review articles, primary papers and databases to locate that elusive fact?The Academic Press FactsBook series will satisfy scientists and clinical researchers suffering from information overload. Each volume provides a catalogue of the essential properties of families of molecules. Gene organization, amino acid sequences, physicochemical properties, and biological activity are presented using a common, easy to follow format. Taken together they compile everything you wanted to know about proteins but were too busy to look for. The Protein Kinase FactsBook: Protein - Tyrosine Kinases contains over 130 entries on members of the family from vertebrates, " Drosophila" , higher plants, yeasts, nematodes, slime moulds and other organisms. Key Features* Subunit structure and isoforms* Genetics* Sequence database accession numbers* Domain structures* Amino acid sequences* Homologues in other species* Patterns of expression* Physiological substrates and specificity determinants* Assays* Enzyme activators and inhibitors* References.
Protein Phosphorylation
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Author : Tony Hunter
language : en
Publisher: Elsevier
Release Date : 1991
Protein Phosphorylation written by Tony Hunter and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with Molecular cloning categories.
This volume provides a compilation of recent methods for studying protein phosphorylation.
Protein Phosphorylation
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Author : D. Grahame Hardie
language : en
Publisher: IRL Press
Release Date : 1993
Protein Phosphorylation written by D. Grahame Hardie and has been published by IRL Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Science categories.
Reversible phosphorylation is one of the major mechanisms by which protein activity is controlled in all eukaryotic cells. Networks of protein kinases and phosphatases, which catalyze phosphorylation and dephosphorylation respectively, are responsible for switching between different pathways of cell division, development, or differentiation in response to hormones or growth factors. This book provides a comprehensive description of current methods for studying protein phosphorylation and the protein kinases and phosphatases which catalyze it. It includes detailed protocols for studying phosphorylation in intact cells, approaches using enzyme inhibitors, purification of serine/threonine-specific protein kinases/phosphatases, analysis of kinase/phosphatase specificity, and cloning relevant cDNAs. Protein Phosphorylation: A Practical Approach will be of great value to all researchers in the fields of intracellular and intercellular signalling, including biochemists, molecular biologists and pharmacologists.
Protein Kinases Advances In Research And Application 2012 Edition
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Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2012-12-26
Protein Kinases Advances In Research And Application 2012 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-26 with Medical categories.
Protein Kinases—Advances in Research and Application: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Protein Kinases. The editors have built Protein Kinases—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Protein Kinases in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Protein Kinases—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Protein Kinases Advances In Research And Application 2011 Edition
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Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2012-01-09
Protein Kinases Advances In Research And Application 2011 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-09 with Medical categories.
Protein Kinases: Advances in Research and Application: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Protein Kinases. The editors have built Protein Kinases: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Protein Kinases in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Protein Kinases: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Protein Kinase Ck2 From Structure To Regulation
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Author : Khalil Ahmed
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Protein Kinase Ck2 From Structure To Regulation written by Khalil Ahmed and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
CK2 is a protein serine/threonine kinase which is a highly conserved and ubiquitous protein kinase. It is localized in the cytoplasmic and nuclear compartments, which accords with its multiple functional activities in the cell. Pertinent to this is also the recognition that a large number of putative substrates for this kinase have been identified in various compartments of the cell. New evidence from several laboratories has further reinforced the involvement of CK2 in signal transduction related to many cellular functions, thus underscoring the significance of its functional role in normal and abnormal cell growth and proliferation. This volume provides an overview of the state of knowledge concerning this intriguing protein kinase. It brings together contributions from leading investigators engaged in research in this field. Key developments during the past three years pertain to the elaboration of the crystal structure and definition of novel functions of the kinase, such as its role as an inhibitor of apoptosis. Additionally, the shuttling of the kinase to various compartments in response to physiological and stress stimuli appears to be a key feature of the functional regulation of its activity in the cell.