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The Renin Angiotensin System


The Renin Angiotensin System
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The Renin Angiotensin System In Cancer Lung Liver And Infectious Diseases


The Renin Angiotensin System In Cancer Lung Liver And Infectious Diseases
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Author : Sukhwinder K. Bhullar
language : en
Publisher: Springer Nature
Release Date : 2023-03-14

The Renin Angiotensin System In Cancer Lung Liver And Infectious Diseases written by Sukhwinder K. Bhullar and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-14 with Medical categories.


This book of the series on “Advances in Biochemistry in Health and Disease” includes state-of-the-art information on the status of renin-angiotensin system (RAS) in the form of 24 chapters. This book has been organized into three sections: (i) General Implications of RAS in human health and Infectious Diseases, (ii) Lung, Liver and Kidney Diseases, and (iii) Development of Cancer. Each chapter has discussed comprehensive knowledge regarding the molecular and cellular aspects of the role of RAS in the pathophysiology and pharmacotherapy of different disease processes. Biochemical mechanisms associated with angiotensin II type 1 and type II receptors, and angiotensin (1-7) MAS receptors for the occurrence of both harmful and beneficial effects of prolonged activation of RAS in different diseases have been outlined. It is noteworthy to point out that different chapter in this book were prepared by recognized global expertise in the area of inflammation, oxidative stress and signal transduction pathways to highlight the role of RAS in different diseases. It is our sincere hope that this book will be of great interest to both biomedical investigators and health professionals as well as graduate students and postdoctoral fellows all over the world.



The Local Cardiac Renin Angiotensin Aldosterone System


The Local Cardiac Renin Angiotensin Aldosterone System
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Author : Edward D. Frohlich
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-09-18

The Local Cardiac Renin Angiotensin Aldosterone System written by Edward D. Frohlich and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-09-18 with Medical categories.


Until recently, the renin-angiotensin-aldosterone system has been considered a systemic endocrine hormonal system exclusively. It is now known that each component of the renin-angiotensin system is produced, synthesized and indeed, present in many organisms including the heart and vessels. This volume presents the most recent clinical and laboratory experiences of the leading physicians and investigators in the field of the local cardiac renin-angiotensin aldosterone system. Cardiovascular, renal and hypertension oriented physicians, investigators and scientists would find this book of interest. Edward D. Frohlich, M.D., M.A.C.P, F.A.C.C., is the Alton Ochsner Distinguished Scientist at the Ochsner Clinic Foundation in New Orleans, Louisiana. He is also Professor of Medicine and of Physiology at Louisiana State University School of Medicine, New Orleans, and Clinical Professor of Medicine and Adjunct Professor of Pharmacology at Tulane University School of Medicine, New Orleans. He is past Editor-in-Chief of the American Heart Association journal HYPERTENSION. Richard N. Re, M.D., is the Section Head, Hypertension at the Ochsner Clinic Foundation in New Orleans, Louisiana. He is also Ochsner's Scientific Director of Research.



The Renin Angiotensin System


The Renin Angiotensin System
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Author : Hideshi Kobayashi
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

The Renin Angiotensin System written by Hideshi Kobayashi and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.


The renin-angiotensin system and the mechanisms regulating this system developed during the adaptive evolution of verte brates, along with many other systems involved in the in tegrated survival of the organism. Because animal species have evolved from common ancestral populations, a basis for the comparison of body structures and physiological processes ex ists among animal groups belonging to different classifications. The comparative approach provides a better understanding of the structure and function of adaptive systems and facilitates the development of general principles governing these systems among animal groups; further, this approach reveals significant characteristics specific to certain animal groups. As the evolu tion of adaptation of animals to environmental conditions is explored, directions for future research are suggested. In this book, advances in research on the renin-angiotensin system are described with emphasis on the comparative aspects. However, since studies on the renin-angiotensin system of birds, reptiles, amphibians and fishes are limited compared with those con ducted in mammals, in some chapters descriptions are con cerned primarily with mammals. It has taken a long time to write this volume, and the topic is a broad one, with new data always emerging; therefore, certain aspects, and sometimes the most recent information, may not be included. Chapters 1-3 and sections 8. 1-8. 4,8. 6, 8. 7 were written by H. K. ; Chapters 4-7 and Section 8. 5 by Y. T. ; Chapter 9 was written by both authors. H. Uemura, M. Nozaki, Y. Okawara, We are indebted to Drs.



Selected Chapters From The Renin Angiotensin System


Selected Chapters From The Renin Angiotensin System
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Author : Aleksandar Kibel
language : en
Publisher: BoD – Books on Demand
Release Date : 2020-08-19

Selected Chapters From The Renin Angiotensin System written by Aleksandar Kibel and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-19 with Medical categories.


Selected Chapters from the Renin-Angiotensin System aims to provide a comprehensive overview of the most important physiological and pathophysiological roles of the renin-angiotensin system (RAS). The complex and convoluted RAS has been investigated for many years and, through rigorous scientific research, many important and previously unknown components and functions of the RAS have come to light. These discoveries have been crucial in the understanding of this system and provide a basis for effective modulation of the system as part of therapeutic strategies for a number of widespread disorders. New studies are continuing to elucidate the RAS and the mechanisms associated with its functions. This book discusses relevant scientific knowledge about the RAS and intends to introduce the reader to cutting-edge research with an accentuation on the mechanisms at the functional/physiological and molecular/cellular levels.



The Protective Arm Of The Renin Angiotensin System Ras


The Protective Arm Of The Renin Angiotensin System Ras
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Author : Thomas Unger
language : en
Publisher: Academic Press
Release Date : 2015-04-18

The Protective Arm Of The Renin Angiotensin System Ras written by Thomas Unger and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-04-18 with Medical categories.


The Protective Arm of the Renin Angiotensin System: Functional Aspects and Therapeutic Implications is the first comprehensive publication to signal the protective role of a distinct part of the renin–angiotensin system (RAS), providing readers with early insight into a complex system which will become of major medical importance in the near future. Focusing on recent research, The Protective Arm of the Renin Angiotensin System presents a host of new experimental studies on specific components of the RAS, namely angiotensin AT2 receptors (AT2R), the angiotensin (1–7) peptide with its receptor Mas, and the enzyme ACE 2, which exert significant beneficial, health-promoting actions by counterbalancing the well-known harmful arm of the RAS with its classical angiotensin AT1 receptor. This innovative concept of the protective arm of the RAS, examined in this reference, represents an indispensable background and will be a strong support for biomedical students, researchers, cardiologists, surgeons, nephrologists, diabetologists, and endocrinologists, as well as any other physician or researcher concerned with RAS physiology, pathophysiology and clinical implications. Provides a complete understanding of the protective side of the Renin Angiotensin System (RAS) involving angiotensin AT2 receptor, ACE2, and Ang(1-7)/Mas receptor Combines the knowledge of editors who pioneered research on the protective renin angiotensin system including; Dr. Thomas Unger, one of the founders of AT2 receptor research; Dr. Ulrike M. Steckelings, who contributed significantly to first preclinical studies with a novel specific AT2-agonist, and Dr. Robson Santos who pioneered research on angiotensin-(1-7) and its receptor Mas. Shows that the protective RAS axes are able to ameliorate the course of several cardiovascular, renal, metabolic and neurological diseases Provides the basis for the understanding of a novel therapeutic approach to stimulate components of the protective arm of the RAS.



Drugs Enzymes And Receptors Of The Renin Angiotensin System


Drugs Enzymes And Receptors Of The Renin Angiotensin System
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Author : Ahsan Husain
language : en
Publisher: CRC Press
Release Date : 2003-09-02

Drugs Enzymes And Receptors Of The Renin Angiotensin System written by Ahsan Husain and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-09-02 with Medical categories.


Since 1898, when Tigerstadt and Bergman first extracted renin from rabbit kidney, the reninrugs, Enzymes and Receptors of the Renin is designed to highlight molecular and clinical approaches to understanding the renin Chapter topics have been specifically chosen to cover selected contemporary, controversial and unresolved issues. A novel and uni



Renin Angiotensin System


Renin Angiotensin System
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Author : Anna Tolekova
language : en
Publisher: BoD – Books on Demand
Release Date : 2017-07-12

Renin Angiotensin System written by Anna Tolekova and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-07-12 with Medical categories.


Exploring the contractile activity of smooth muscle segments isolated from various organs of healthy animals and animals with experimentally induced diabetes, she obtained original data about angiotensin II-induced force and time parameters. For the first time, she established the effect of ghrelin on angiotensin II-provoked contraction of the urinary bladder. Original data on the role of both types of angiotensin receptors for the contractile activity of the various segments of the gastrointestinal tract and bladder were obtained. By applying specific software for force and time parameter analysis, the contribution of different types of angiotensin receptors on muscle contractility has been shown. The new methodology was used to analyze the data obtained during the registration of smooth muscle relaxation activity, which allows the determination of not only the magnitude of the mechanical response but also the parameters related to the time and speed of the contractions. Plasma renin activity models have been developed using mathematical approaches to predict the effect of different drug doses on the behavior of the system.



Frontiers In Research Of The Renin Angiotensin System On Human Disease


Frontiers In Research Of The Renin Angiotensin System On Human Disease
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Author : Po Sing Leung
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-10-16

Frontiers In Research Of The Renin Angiotensin System On Human Disease written by Po Sing Leung and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-10-16 with Medical categories.


The primary aim of this book is to provide a topical and timely forum for the critical appraisal of an area of renin-angiotensin system (RAS) research that is expanding rapidly. In this respect, a collection of thirteen chapters from distinguished and world-class experts in the field has been presented on the contemporary research of the RAS and their implications in human disease. This book is an indispensable tool tailor-made for specialists, non-specialists and the novice.



Cellular And Molecular Biology Of The Renin Angiotensin System


Cellular And Molecular Biology Of The Renin Angiotensin System
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Author : Mohan K. Raizada
language : en
Publisher: CRC Press
Release Date : 2018-01-18

Cellular And Molecular Biology Of The Renin Angiotensin System written by Mohan K. Raizada and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-18 with Science categories.


Cellular and Molecular Biology of the Renin-Angiotensin System provides the first review and update of the state-of-the-art cellular and molecular aspects of the renin-angiotensin system. The book presents detailed analyses from world experts on each component of this system, including future directions. Topics range from angiotensin II receptor subtypes to processing of renin to the use of transgenic animal models for studying the role of this system in hypertension. Cellular and Molecular Biology of the Renin-Angiotensin System is essential reading for physiologists of the renin-angiotensin system, endocrinologists, cardiovascular specialists, renal physiologists, and neurobiologists.



Renin Angiotensin System And Cardiovascular Disease


Renin Angiotensin System And Cardiovascular Disease
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Author : Walmor C. DeMello
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-09-01

Renin Angiotensin System And Cardiovascular Disease written by Walmor C. DeMello and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-09-01 with Medical categories.


This book offers the latest research into the role of the renin angiotensin system on cardiac and vascular functions and in cardiovascular diseases. It covers vital aspects such as intracellular signaling and regulation of cell volume in the failing heart.