Selected Chapters From The Renin Angiotensin System
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Selected Chapters From The Renin Angiotensin System
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Author : Aleksandar Kibel
language : en
Publisher: BoD – Books on Demand
Release Date : 2020-08-19
Selected Chapters From The Renin Angiotensin System written by Aleksandar Kibel and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-19 with Medical categories.
Selected Chapters from the Renin-Angiotensin System aims to provide a comprehensive overview of the most important physiological and pathophysiological roles of the renin-angiotensin system (RAS). The complex and convoluted RAS has been investigated for many years and, through rigorous scientific research, many important and previously unknown components and functions of the RAS have come to light. These discoveries have been crucial in the understanding of this system and provide a basis for effective modulation of the system as part of therapeutic strategies for a number of widespread disorders. New studies are continuing to elucidate the RAS and the mechanisms associated with its functions. This book discusses relevant scientific knowledge about the RAS and intends to introduce the reader to cutting-edge research with an accentuation on the mechanisms at the functional/physiological and molecular/cellular levels.
The Renin Angiotensin System
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Author : Hideshi Kobayashi
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
The Renin Angiotensin System written by Hideshi Kobayashi and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
The renin-angiotensin system and the mechanisms regulating this system developed during the adaptive evolution of verte brates, along with many other systems involved in the in tegrated survival of the organism. Because animal species have evolved from common ancestral populations, a basis for the comparison of body structures and physiological processes ex ists among animal groups belonging to different classifications. The comparative approach provides a better understanding of the structure and function of adaptive systems and facilitates the development of general principles governing these systems among animal groups; further, this approach reveals significant characteristics specific to certain animal groups. As the evolu tion of adaptation of animals to environmental conditions is explored, directions for future research are suggested. In this book, advances in research on the renin-angiotensin system are described with emphasis on the comparative aspects. However, since studies on the renin-angiotensin system of birds, reptiles, amphibians and fishes are limited compared with those con ducted in mammals, in some chapters descriptions are con cerned primarily with mammals. It has taken a long time to write this volume, and the topic is a broad one, with new data always emerging; therefore, certain aspects, and sometimes the most recent information, may not be included. Chapters 1-3 and sections 8. 1-8. 4,8. 6, 8. 7 were written by H. K. ; Chapters 4-7 and Section 8. 5 by Y. T. ; Chapter 9 was written by both authors. H. Uemura, M. Nozaki, Y. Okawara, We are indebted to Drs.
Drugs Enzymes And Receptors Of The Renin Angiotensin System
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Author : Ahsan Husain
language : en
Publisher: CRC Press
Release Date : 2003-09-02
Drugs Enzymes And Receptors Of The Renin Angiotensin System written by Ahsan Husain and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-09-02 with Medical categories.
Since 1898, when Tigerstadt and Bergman first extracted renin from rabbit kidney, the reninrugs, Enzymes and Receptors of the Renin is designed to highlight molecular and clinical approaches to understanding the renin Chapter topics have been specifically chosen to cover selected contemporary, controversial and unresolved issues. A novel and uni
The Renin Angiotensin System In Cardiovascular Disease
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Author : Naranjan S. Dhalla
language : en
Publisher: Springer Nature
Release Date : 2023-01-01
The Renin Angiotensin System In Cardiovascular Disease written by Naranjan S. Dhalla and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-01-01 with Medical categories.
This book on “Renin-Angiotensin System in Cardiovascular Disease” includes 25 chapters, which are organized in three sections, namely (i) modulatory aspects, (ii) pathophysiological aspects, and (iii) pharmacotherapeutic aspects. It includes an updated as well as comprehensive knowledge about molecular and cellular aspects for the role of the renin-angiotensin system (RAS) in the pathophysiology and therapy of cardiovascular diseases such as hypertension, atherosclerosis, ischemic heart disease, and heart failure. This book emphasizes the molecular and cellular mechanisms, signaling transduction pathways involved in the development of different cardiovascular diseases due to the prolonged activation of RAS. Furthermore, biochemical mechanisms are outlined for the inhibition of this system by the blockade of angiotensin converting enzyme as well as angiotensin II type 1 receptors in patients suffering from cardiovascular abnormalities. Since cardiovascular disease is the number one cause of death worldwide, leading to approximately 17.9 million deaths each year, there is a keen interest in understanding the pathogenesis and improving its therapy. In this regard, we can attest that this book provides ample information about essential components of RAS and their role in the development of cardiovascular disease. From the selection of recognized global experts in their area of investigation, this book can be seen to cover diverse cardiovascular aspects and molecular and cellular mechanisms of angiotensin II action for the development of different cardiovascular abnormalities. It is our contention that this book will be most suitable for promoting knowledge in the field of RAS biology and will be of great interest to health professionals involved in both experimental and clinical cardiology as well as academic investigators and cardiovascular scientists, graduate students, and fellows worldwide.
Renin Angiotensin System And The Heart
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Author : Walmor C. De Mello
language : en
Publisher: John Wiley & Sons
Release Date : 2005-10-31
Renin Angiotensin System And The Heart written by Walmor C. De Mello and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-10-31 with Medical categories.
Recent studies have shown that the heart possesses an intrinsic renin angiotensin system that is controlled by tissue-specific parameters that are activated by biomechanical stress. This book reviews the latest information on the way in which both the plasma and cardiac renin angiotensin systems affect heart function. It covers the cell and molecular biology of these systems, with contributions on renin synthesis, uptake and the intracellular signalling pathways. Particular insight comes from transgenic mouse models in which either mouse or human genes for various components of the renin angiotensin system are expressed. Other topics covered include wound healing as well as the trophic effects of aldosterone. Contains the most recent findings on the renin angiotensin system and the heart Written by an international team of distinguished scientists Covers both the cellular and molecular basis of the renin angiotensin system and the clinical relevance of this research
Textbook Of Nephro Endocrinology
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Author : Ajay K. Singh
language : en
Publisher: Academic Press
Release Date : 2009-01-12
Textbook Of Nephro Endocrinology written by Ajay K. Singh and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-01-12 with Medical categories.
The Textbook of Nephro-Endocrinology is the definitive translational reference in the field of nephro-endocrinology, investigating both the endocrine functions of the kidneys and how the kidney acts as a target for hormones from other organ systems. It offers researchers and clinicians expert, gold-standard analyses of nephro-endocrine research and translation into the treatment of diseases such as anemia, chronic kidney disease (CKD), rickets, osteoporosis, and, hypoparathyroidism. Investigates both the endocrine functions of the kidneys and how the kidney acts as a target for hormones from other organ systems Presents a uniquely comprehensive and cross-disciplinary look at all aspects of nephro-endocrine disorders in one reference work Clear translational presentations by the top endocrinologists and nephrologists in each specific hormone or functional/systems field
Cellular And Molecular Biology Of The Renin Angiotensin System
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Author : Mohan K. Raizada
language : en
Publisher: CRC Press
Release Date : 2017-12-08
Cellular And Molecular Biology Of The Renin Angiotensin System written by Mohan K. Raizada and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-12-08 with categories.
SECTION VI: RENIN-ANGIOTENSIN AND HUMAN HYPERTENSION -- Chapter 20 Derangements in Renin-Angiotensin Regulation in the Pathogenesis of Hypertension -- Chapter 21 Genes of the Renin-Angiotensin System and the Genetics of Human Hypertension -- Index
The Renin Angiotensin Aldosterone System
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Author : Sean E. Thatcher
language : en
Publisher: Humana Press
Release Date : 2017-05-13
The Renin Angiotensin Aldosterone System written by Sean E. Thatcher and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-05-13 with Science categories.
This volume discusses protocols that aid in measuring different components in the renin-angiotensin-aldosterone system (RAAS). The book also looks at the methods used to assess angiotensin peptides and discerning the influence of RAAS components on different mammalian diseases. The chapters cover topics such as the use of fluorescent substrate to measure ACE2 activity in the mouse abdominal aorta, blood pressure monitoring using the radio telemetry method, and the analysis of angiotensin metabolism in the kidney using mass spectrometry. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting edge and comprehensive, The Renin-Angiotensin-Aldosterone Systems: Methods and Protocols is a valuable resource that provides scientists and researchers with the best approaches to examine RAAS.
Frontiers In Research Of The Renin Angiotensin System On Human Disease
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Author : Po Sing Leung
language : en
Publisher: Springer
Release Date : 2009-09-03
Frontiers In Research Of The Renin Angiotensin System On Human Disease written by Po Sing Leung and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-09-03 with Medical categories.
The primary aim of this book is to provide a topical and timely forum for the critical appraisal of an area of renin-angiotensin system (RAS) research that is expanding rapidly. In this respect, a collection of thirteen chapters from distinguished and world-class experts in the field has been presented on the contemporary research of the RAS and their implications in human disease. This book is an indispensable tool tailor-made for specialists, non-specialists and the novice.
Aldosterone Mineralocorticoid Receptor
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Author : Brian Harvey
language : en
Publisher: BoD – Books on Demand
Release Date : 2019-09-25
Aldosterone Mineralocorticoid Receptor written by Brian Harvey and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-25 with Medical categories.
This book is an open access dissemination of the EU COST Action ADMIRE in Aldosterone/Mineralocorticoid Receptor (MR) physiology and pathophysiology. Aldosterone is the major hormone regulating blood pressure. Alterations in blood levels of aldosterone and genetic mutations in the MR receptor are major causes of hypertension and comorbidities. Many of the drugs in clinical use, and in development for treating hypertension, target aldosterone and MR actions in the kidney and cardiovascular system. The ADMIRE book assembles review chapters from 16 European ADMIRE laboratories providing the latest insights into mechanisms of aldosterone synthesis/secretion, aldosterone/MR physiology and signaling, and the pathophysiological roles of aldosterone/MR activation.
