The Role Of Mast Cells In Fetal Wound Healing
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The Role Of Mast Cells In Fetal Wound Healing
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Author : Melissa Meleski
language : en
Publisher:
Release Date : 2010
The Role Of Mast Cells In Fetal Wound Healing written by Melissa Meleski and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with categories.
Abstract: Normally, in adults, wounds to the skin end in the formation of a scar. Scar tissue formation inhibits the normal functioning of skin and can lead to limited joint mobility, impaired growth, and wound dehiscence. This abnormal tissue often results from excessive inflammation at the wound site. Recently, studies have found that major differences exist in the healing process of adult and fetal skin, the most noteworthy of which is the lack of scar formation in fetal wounds. In mice, scarless healing occurs up until embryonic day sixteen (E16). One possible reason for the disparity in wound healing between adult and fetal skin could be the presence of different numbers of mast cells, a specific type of inflammatory cell. Toluidine blue was used to identify mast cells within both unwounded and wounded E15 and E18 skin. A significantly larger number of mast cells were found in unwounded E18 skin, which forms scars after injury, than were found in unwounded E15 skin. The mast cells in the unwounded E18 skin also possessed more granules than those found in the unwounded E15 skin. Similarly, a significantly larger number of mast cells were found in wounded E18 skin than were found in wounded E15 skin. The mast cells in the wounded E18 skin also released a larger number of granules indicating the presence of more activated mast cells. The results obtained in this study suggest a relationship between mast cell presence and the transition from scarless and fibrotic healing which takes place during development. These findings could lead to future studies which could develop new drugs and therapies that may help reduce or even eliminate scar formation in the future.
Fetal Wound Healing
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Author : N. Scott Adzick
language : en
Publisher: Elsevier Publishing Company
Release Date : 1992
Fetal Wound Healing written by N. Scott Adzick and has been published by Elsevier Publishing Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with Medical categories.
The ability of foetal tissue to heal without scarring is now well documented, but the potentially far-reaching implications of this process for the practice of surgery and the management of healing are just beginning to be understood. This book provides up-to-date information on the subject.
Textbook On Scar Management
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Author : Luc Téot
language : en
Publisher: Springer Nature
Release Date : 2020-12-07
Textbook On Scar Management written by Luc Téot and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-07 with Medical categories.
This text book is open access under a CC BY 4.0 license. Written by a group of international experts in the field and the result of over ten years of collaboration, it allows students and readers to gain to gain a detailed understanding of scar and wound treatment – a topic still dispersed among various disciplines. The content is divided into three parts for easy reference. The first part focuses on the fundamentals of scar management, including assessment and evaluation procedures, classification, tools for accurate measurement of all scar-related elements (volume density, color, vascularization), descriptions of the different evaluation scales. It also features chapters on the best practices in electronic-file storage for clinical reevaluation and telemedicine procedures for safe remote evaluation. The second section offers a comprehensive review of treatment and evidence-based technologies, presenting a consensus of the various available guidelines (silicone, surgery, chemical injections, mechanical tools for scar stabilization, lasers). The third part evaluates the full range of emerging technologies offered to physicians as alternative or complementary solutions for wound healing (mechanical, chemical, anti-proliferation). Textbook on Scar Management will appeal to trainees, fellows, residents and physicians dealing with scar management in plastic surgery, dermatology, surgery and oncology, as well as to nurses and general practitioners
Wound Healing Tissue Repair And Regeneration In Diabetes
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Author : Debasis Bagchi
language : en
Publisher: Academic Press
Release Date : 2020-05-08
Wound Healing Tissue Repair And Regeneration In Diabetes written by Debasis Bagchi and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-05-08 with Health & Fitness categories.
Wound Healing, Tissue Repair and Regeneration in Diabetes explores a wide range of topics related to wound healing, tissue repair and regeneration, putting a special focus on diabetes and obesity. The book addresses the molecular and cellular pathways involved in the process of wound repair and regeneration. Other sections explore a wide spectrum of nutritional supplements and novel therapeutic approaches, provide a comprehensive overview, present various types of clinical aspects related to diabetic wounds, including infection, neuropathy, and vasculopathy, provide an exhaustive review of various foods, minerals, supplements and phytochemicals that have been proven beneficial, and assess future directions. This book is sure to be a welcome resource for nutritionists, practitioners, surgeons, nurses, wound researchers and other health professionals. Explains diabetic wounds and their complications Assesses the role of nutraceuticals, herbal supplements and other modalities for use in treating diabetic wounds Provides protocols for diabetic wound management
Cell Movement
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Author : Thomas Abreu
language : en
Publisher: Nova Science Publishers
Release Date : 2009
Cell Movement written by Thomas Abreu and has been published by Nova Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with Cell differentiation categories.
Cell movement is a complex phenomenon primarily driven by the actin network beneath the cell membrane, and can be divided into three general components: protrusion of the leading edge of the cell, adhesion of the leading edge and deadhesion at the cell body and rear, and cytoskeletal contraction to pull the cell forward. Each of these steps is driven by physical forces generated by unique segments of the cytoskeleton. This review examines the specific physics underlying these phases of cell movement and the origins of the forces that drive locomotion. Cell movement or motility is a highly dynamic phenomenon that is essential to a variety of biological processes such as the development of an organism (morphogenesis), wound healing, cancer metastasis and immune response. For example, during morphogenesis there is a targeted movement of dividing cells to specific sites to form tissues and organs. For wound healing to occur, cells such as neutrophils (white blood cells) and macrophages (cells that ingest bacteria) move to the wound site to kill the microorganisms that cause infection, and fibroblasts (connective tissue cells) move there to remodel damaged structures. This book presents important research in the field from around the globe.
Wound Healing
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Author : Kursad Turksen
language : en
Publisher: John Wiley & Sons
Release Date : 2018-02-21
Wound Healing written by Kursad Turksen and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-02-21 with Science categories.
A comprehensive resource on the recent developments of stem cell use in wound healing With contributions from experts in the field, Wound Healing offers a thorough review of the most recent findings on the use of stem cells to heal wounds. This important resource covers both the basic and translational aspects of the field. The contributors reveal the great progress that has been made in recent years and explore a wide range of topics from an overview of the stem cell process in wound repair to inflammation and cancer. They offer a better understanding of the identities of skin stem cells as well as the signals that govern their behavior that contributes to the development of improved therapies for scarring and poorly healing wounds. Comprehensive in scope, this authoritative resource covers a wealth of topics such as: an overview of stem cell regeneration and repair, wound healing and cutaneous wound healing, the role of bone marrow derived stems cells, inflammation in wound repair, role and function of inflammation in wound repair, and much more. This vital resource: Provides a comprehensive overview of stem cell use in wound healing, including both the basic and translational aspects of the field Covers recent developments and emerging subtopics within the field Offers an invaluable resource to clinical and basic researchers who are interested in wound healing, stem cells, and regenerative medicine Contains contributions from leading experts in the field of wound healing and care Wound Healing offers clinical researchers and academics a much-needed resource written by noted experts in the field that explores the role of stem cells in the repair and restoration of healing wounds.
Cutaneous Wound Healing
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Author : Vincent Falanga
language : en
Publisher: CRC Press
Release Date : 2001-08-23
Cutaneous Wound Healing written by Vincent Falanga and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-08-23 with Medical categories.
Gene therapy, bioengineered skin, and other methods in advanced biology are revolutionizing the treatment of wounds. Written by experts in research and clinical practice, Cutaneous Wound Healing examines the current knowledge and emerging treatment methods. This volume explains the normal molecular and cellular functions that occur when a wound heals, as well as dysfunctional events, such as a chronic wound or an ulcer. Such dysfunctions signal an imbalance in the body, explained here along with possible treatments. The book's mini-atlas is an indispensable reference tool. Dermatologists, plastic surgeons, and general practitioners can benefit from this text.
Indwelling Neural Implants
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Author : William M. Reichert
language : en
Publisher: CRC Press
Release Date : 2007-12-17
Indwelling Neural Implants written by William M. Reichert and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-12-17 with Medical categories.
Despite enormous advances made in the development of external effector prosthetics over the last quarter century, significant questions remain, especially those concerning signal degradation that occurs with chronically implanted neuroelectrodes. Offering contributions from pioneering researchers in neuroprosthetics and tissue repair, Indwel
Tendon Regeneration
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Author : Manuela E. Gomes
language : en
Publisher: Academic Press
Release Date : 2015-08-08
Tendon Regeneration written by Manuela E. Gomes and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-08-08 with Science categories.
Tendon Regeneration: Understanding Tissue Physiology and Development to Engineer Functional Substitutes is the first book to highlight the multi-disciplinary nature of this specialized field and the importance of collaboration between medical and engineering laboratories in the development of tissue-oriented products for tissue engineering and regenerative medicine (TERM) strategies. Beginning with a foundation in developmental biology, the book explores physiology, pathology, and surgical reconstruction, providing guidance on biological approaches that enhances tendon regeneration practices. Contributions from scientists, clinicians, and engineers who are the leading figures in their respective fields present recent findings in tendon stem cells, cell therapies, and scaffold treatments, as well as examples of pre-clinical models for translational therapies and a view of the future of the field. Provides an overview of tendon biology, disease, and tissue engineering approaches Presents modern, alternative approaches to developing functional tissue solutions discussed Includes valuable information for those interested in tissue engineering, tissue regeneration, tissue physiology, and regenerative medicine Explores physiology, pathology, and surgical reconstruction, building a natural progression that enhances tendon regeneration practices Covers recent findings in tendon stem cells, cell therapies, and scaffold treatments, as well as examples of pre-clinical models for translational therapies and a view of the future of the field
Mechanisms Of Vascular Disease
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Author : Robert Fitridge
language : en
Publisher: University of Adelaide Press
Release Date : 2011
Mechanisms Of Vascular Disease written by Robert Fitridge and has been published by University of Adelaide Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Medical categories.
New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.