Fetal Wound Healing
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Fetal Wound Healing
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Author : N. Scott Adzick
language : en
Publisher: Elsevier Publishing Company
Release Date : 1992
Fetal Wound Healing written by N. Scott Adzick and has been published by Elsevier Publishing Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with Medical categories.
The ability of foetal tissue to heal without scarring is now well documented, but the potentially far-reaching implications of this process for the practice of surgery and the management of healing are just beginning to be understood. This book provides up-to-date information on the subject.
Fetal Wound Healing
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Author : Adzick Longaker
language : en
Publisher: Gower Publishing Company, Limited
Release Date : 1992-01-01
Fetal Wound Healing written by Adzick Longaker and has been published by Gower Publishing Company, Limited this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992-01-01 with Medical categories.
The Role Of Mast Cells In Fetal Wound Healing
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Author : Melissa Meleski
language : en
Publisher:
Release Date : 2010
The Role Of Mast Cells In Fetal Wound Healing written by Melissa Meleski and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with categories.
Abstract: Normally, in adults, wounds to the skin end in the formation of a scar. Scar tissue formation inhibits the normal functioning of skin and can lead to limited joint mobility, impaired growth, and wound dehiscence. This abnormal tissue often results from excessive inflammation at the wound site. Recently, studies have found that major differences exist in the healing process of adult and fetal skin, the most noteworthy of which is the lack of scar formation in fetal wounds. In mice, scarless healing occurs up until embryonic day sixteen (E16). One possible reason for the disparity in wound healing between adult and fetal skin could be the presence of different numbers of mast cells, a specific type of inflammatory cell. Toluidine blue was used to identify mast cells within both unwounded and wounded E15 and E18 skin. A significantly larger number of mast cells were found in unwounded E18 skin, which forms scars after injury, than were found in unwounded E15 skin. The mast cells in the unwounded E18 skin also possessed more granules than those found in the unwounded E15 skin. Similarly, a significantly larger number of mast cells were found in wounded E18 skin than were found in wounded E15 skin. The mast cells in the wounded E18 skin also released a larger number of granules indicating the presence of more activated mast cells. The results obtained in this study suggest a relationship between mast cell presence and the transition from scarless and fibrotic healing which takes place during development. These findings could lead to future studies which could develop new drugs and therapies that may help reduce or even eliminate scar formation in the future.
The Molecular Control Of Fetal Wound Healing
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Author : Jacqueline Therese Teusner
language : en
Publisher:
Release Date : 2001
The Molecular Control Of Fetal Wound Healing written by Jacqueline Therese Teusner and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with Fetus categories.
Scarless Wound Healing
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Author : A. David Rodrigues
language : en
Publisher: CRC Press
Release Date : 2000-06-13
Scarless Wound Healing written by A. David Rodrigues and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-06-13 with Medical categories.
Applies recent molecular discoveries to the evolving treatment of skin therapy and points out future research areas. Presenting the most up-to-date research in wound treatment, this comprehensive reference analyzes the critical alterations in the composition and organization of the extracellular matrix following injury. Beginning with a chem
Textbook On Scar Management
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Author : Luc Téot
language : en
Publisher: Springer Nature
Release Date : 2020-12-07
Textbook On Scar Management written by Luc Téot and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-07 with Medical categories.
This text book is open access under a CC BY 4.0 license. Written by a group of international experts in the field and the result of over ten years of collaboration, it allows students and readers to gain to gain a detailed understanding of scar and wound treatment – a topic still dispersed among various disciplines. The content is divided into three parts for easy reference. The first part focuses on the fundamentals of scar management, including assessment and evaluation procedures, classification, tools for accurate measurement of all scar-related elements (volume density, color, vascularization), descriptions of the different evaluation scales. It also features chapters on the best practices in electronic-file storage for clinical reevaluation and telemedicine procedures for safe remote evaluation. The second section offers a comprehensive review of treatment and evidence-based technologies, presenting a consensus of the various available guidelines (silicone, surgery, chemical injections, mechanical tools for scar stabilization, lasers). The third part evaluates the full range of emerging technologies offered to physicians as alternative or complementary solutions for wound healing (mechanical, chemical, anti-proliferation). Textbook on Scar Management will appeal to trainees, fellows, residents and physicians dealing with scar management in plastic surgery, dermatology, surgery and oncology, as well as to nurses and general practitioners
Annual Meeting Wound Healing Society
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Author :
language : en
Publisher:
Release Date : 1992
Annual Meeting Wound Healing Society written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with Wound healing categories.
Cellular And Molecular Mechanisms Involved In Scarless Wound Healing In The Fetal Skin
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Author :
language : en
Publisher:
Release Date : 2016
Cellular And Molecular Mechanisms Involved In Scarless Wound Healing In The Fetal Skin written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016 with categories.
Wound Healing Tissue Repair And Regeneration In Diabetes
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Author : Debasis Bagchi
language : en
Publisher: Academic Press
Release Date : 2020-05-08
Wound Healing Tissue Repair And Regeneration In Diabetes written by Debasis Bagchi and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-05-08 with Health & Fitness categories.
Wound Healing, Tissue Repair and Regeneration in Diabetes explores a wide range of topics related to wound healing, tissue repair and regeneration, putting a special focus on diabetes and obesity. The book addresses the molecular and cellular pathways involved in the process of wound repair and regeneration. Other sections explore a wide spectrum of nutritional supplements and novel therapeutic approaches, provide a comprehensive overview, present various types of clinical aspects related to diabetic wounds, including infection, neuropathy, and vasculopathy, provide an exhaustive review of various foods, minerals, supplements and phytochemicals that have been proven beneficial, and assess future directions. This book is sure to be a welcome resource for nutritionists, practitioners, surgeons, nurses, wound researchers and other health professionals. Explains diabetic wounds and their complications Assesses the role of nutraceuticals, herbal supplements and other modalities for use in treating diabetic wounds Provides protocols for diabetic wound management
Guided Regeneration Of The Human Skin
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Author : Erika Nyman
language : en
Publisher: Linköping University Electronic Press
Release Date : 2015-03-17
Guided Regeneration Of The Human Skin written by Erika Nyman and has been published by Linköping University Electronic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-03-17 with Burns and scalds categories.
Every day and in all parts of the world, humans experience different grades of wounding and tissue loss of the skin, thus initiating one of the most complex biological processes. Acute and chronic wounds, as well as the additional problem of skin scarring, involve not only great suffering for the patient but also extensive health care costs for the society. Although the wound-healing process is a wellstudied field much knowledge must be gained to unlock the door to regenerative pathways in humans. Epidermis heals by complete regeneration, but dermal and full thickness injuries heal with fibrosis and scar formation. In Papers I and II, we studied whether dermal scarring could be turned into regeneration by using two different types of threedimensional dermal scaffolds. In Paper I, we studied a solid scaffold made of poly(urethane urea), initially in vitro then followed by in vivo studies. In Paper II, we intradermally injected a liquid three-dimensional scaffold consisting of porous gelatin spheres in human healthy volunteers. Both materials showed ingrowth of functional fibroblasts and blood vessels and appeared to stimulate regeneration while slowly degrading. This finding could be of significant clinical importance, for example in burn wound care or after cancer surgery. In Papers III and IV, we wanted to study the effects of amniotic fluid and hyaluronic acid on adult wound healing, because early fetal wounds re-epithelialize rapidly and naturally heal dermis by regeneration without the need of a dermal scaffold. Amniotic fluid, naturally rich in hyaluronic acid, induced an accelerated reepithelialization of adult human wounds in vitro, and hyaluronic acid seemed to be important for this effect. Stimulation with exogenous hyaluronic acid in vivo induced accelerated re-epithelialization and an altered protein expression in healthy human volunteers. The inflammatory phase of wound healing, as measured by tissue viability imaging, was not affected by hyaluronic acid. Elucidating the effects of amniotic fluid and hyaluronic acid on the wound-healing process may allow improved treatment of wounds with impaired healing. Studies on finding new dermal scaffolds and studies on the positive effect of amniotic fluid or hyaluronic acid on the wound-healing process are two different ways of gaining insight that may lead to regeneration and improved wound healing for the patient.