The Role Of Reactive Oxygen Species In Protective Immunity

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The Role Of Reactive Oxygen Species In Protective Immunity
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Author : Denis Martinvalet
language : en
Publisher: Frontiers Media SA
Release Date : 2022-02-25
The Role Of Reactive Oxygen Species In Protective Immunity written by Denis Martinvalet and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-25 with Medical categories.
Antioxidants In Sport Nutrition
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Author : Manfred Lamprecht
language : en
Publisher: CRC Press
Release Date : 2014-09-17
Antioxidants In Sport Nutrition written by Manfred Lamprecht and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-09-17 with Health & Fitness categories.
Antioxidant use in sports is controversial due to existing evidence that it both supports and hurts athletic performance. This book presents information on antioxidants, specifically for athletes, and their roles in sports nutrition. It stresses how antioxidants affect exercise performance, health, and immunity. Chapters cover oxidative stress; basic nutrition for athletes; major dietary antioxidants; sports supplements; performance/adaptation to exercise; antioxidants role in health and immunity; reviews on vitamins C, E, beta-carotene, and minerals in sports nutrition; and roles polyphenols play in high-performance sport.
Tularemia Epidemiology Ecology Genomics Immunity And Pathogenesis
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Author : Marina Santic
language : en
Publisher: Frontiers Media SA
Release Date : 2020-01-22
Tularemia Epidemiology Ecology Genomics Immunity And Pathogenesis written by Marina Santic and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-22 with categories.
Tularemia is a severe anthropozoonosis caused by Francisella tularensis. The genus Francisella contains five species: F. tularensis, F. philomiragia, F. hispaniensis, F. noatunensis and F. novicida. First described in 1911 in Tulare County, California, it has since been reported worldwide, capable of infecting more than 250 vertebrates and invertebrate species. Although it causes disease in various animal species, no animal has been identified as a main reservoir of this pathogen. Humans acquire infection by several routes, including direct contact with infected animals, ingestion of water or food contaminated by infected animals, exposure to infected arthropod vectors or by inhalation of infective aerosols resulting in pneumonic, oropharyngeal, glandular, ulceroglandular or oculoglandular tularemia. The clinical presentation of human tularemia depends on route of the infection, the causative Francisella strain, and the immune response of the host. A live attenuated vaccine (LVS) has been available for more than 50 years, however, unlikely to become licensed in the future due to a lack of understanding of the genetic basis for its attenuation. Due to the ease of its dissemination, its multiple routes of infection, its low dose of infection, severe morbidity, and high rate of mortality, F. tularensis subsp. tularensis has been classified as a category A bioterrorism agent by the CDC. Many virulence factors of F. tularensis have been discovered and investigated, but more in-depth host pathogen interaction analyses are needed to define mechanisms of pathogenicity and virulence of this unique pathogen.
Systems Biology Of Free Radicals And Antioxidants
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Author : Ismail Laher
language : en
Publisher: Springer
Release Date : 2014-06-16
Systems Biology Of Free Radicals And Antioxidants written by Ismail Laher and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-06-16 with Medical categories.
The focus of this collection of illustrated reviews is to discuss the systems biology of free radicals and anti-oxidants. Free radical induced cellular damage in a variety of tissues and organs is reviewed, with detailed discussion of molecular and cellular mechanisms. The collection is aimed at those new to the field, as well as clinicians and scientists with long standing interests in free radical biology. A feature of this collection is that the material also brings insights into various diseases where free radicals are thought to play a role. There is extensive discussion of the success and limitations of the use of antioxidants in several clinical settings.
Immunity To Human Fungal Pathogens Mechanisms Of Host Recognition Protection Pathology And Fungal Interference
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Author : Steven P. Templeton
language : en
Publisher: Frontiers Media SA
Release Date : 2019-01-24
Immunity To Human Fungal Pathogens Mechanisms Of Host Recognition Protection Pathology And Fungal Interference written by Steven P. Templeton and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-01-24 with categories.
Fungi are found in virtually every environment, and comprise a significant portion of the normal microflora of healthy individuals. Some species of fungi are aeroallergen sources capable of inducing sensitization and causing exacerbation of asthma and respiratory allergy. Others are transmissible between hosts and may cause no symptoms in healthy individuals. However, immune suppressed individuals may develop invasive disease marked by tissue invasion with a potential for widespread dissemination. Existing therapies for patients consist of antifungal drugs, yet these require prolonged administration with the possibility of adverse side effects, and may be rendered ineffective by the emergence of antifungal-resistant strains. It is therefore of interest to increase our understanding of host-pathogen interactions in order to facilitate the development of new therapies for individuals suffering from fungal infection and disease. These early interactions are shaped by an array of constituent and secreted factors that stimulate or inhibit host immune responses toward protective or detrimental immunity. Likewise, an array of preformed factors and tissue-resident cells provide early protection from fungal infection and provide extracellular signals that result in localized recruitment of inflammatory cells and determine the character of subsequent adaptive antifungal immunity. This Research Topic explores the host and fungal pathways that program innate and adaptive immunity and the immune cells, molecules, and regulatory pathways that comprise protective or detrimental responses to fungal exposure or infection. Over 200 authors contributed reviews, opinions, or original research focusing on antifungal immunity in humans and in experimental models. We believe that the results of these efforts provide a benchmark for further advances and improved antifungal therapies.
Innate Immunity Pattern Recognition And Effector Mechanisms
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Author : Uday Kishore
language : en
Publisher: Springer Nature
Release Date : 2025-08-08
Innate Immunity Pattern Recognition And Effector Mechanisms written by Uday Kishore and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-08-08 with Medical categories.
This contributed volume follows up and expands upon Target Pattern Recognition in Innate Immunity (2009), providing a much-needed update on an area that has surged to the forefront of medical research in recent years. From the initial idea of pattern recognition on microbial surfaces, innate immunity is now recognized as a key player in human health and disease, by virtue of its ability to regulate adaptive immune responses with important physiological and pathological consequences. This book presents cutting edge research and future perspectives on nearly all aspects of innate immunity. Coverage includes cells of the innate immune system, pattern recognition receptors and effector mechanisms, soluble PRRs and humoral factors, immune response to viral, bacterial, fungal, and parasitic pathogens, disease mechanisms, and comparative studies in non-mammalian innate immunity. It is an excellent introduction to the field for students, and state of the art reference for researchers and professionals.
Malaria Immunology
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Author : Peter Perlmann
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2002-01-01
Malaria Immunology written by Peter Perlmann and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-01-01 with Medical categories.
Despite extensive efforts to control it, malaria is still one of the most devastating infectious diseases worldwide. This book, now in its second edition, provides a broad and up-to-date overview of the rapidly expanding field of malaria immunology and its importance in the control of this disease. The first section deals with the malaria parasite and its interactions with both the vertebrate host and the mosquitoes which transmit the disease. In the second part, the mechanisms of immunity and their regulation by environmental and genetic factors are discussed. Finally, this volume contains several chapters on malaria vaccine development, describing the application of the most recent vaccine technologies as well as ongoing and planned vaccine trials. Authored by well-recognized experts, this volume not only demonstrates the rapid progress being made in the search for vaccines against malaria, but also broadens our understanding of immunity to infection in general. It is therefore highly recommended reading for all scientists and professionals in the fields of immunology, infection and vaccine development.
Oxford Textbook Of Medicine
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Author : D. A. Warrell
language : en
Publisher:
Release Date : 2005
Oxford Textbook Of Medicine written by D. A. Warrell and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Medical categories.
Roles Of Fc Receptors In Disease And Therapy
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Author : Latha P. Ganesan
language : en
Publisher: Frontiers Media SA
Release Date : 2020-07-22
Roles Of Fc Receptors In Disease And Therapy written by Latha P. Ganesan and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-22 with categories.
Cutting Edge Approaches For Cns Protection And Repair Focus On Vascular And Degenerative Disorders
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Author : Johannes Boltze
language : en
Publisher: Frontiers Media SA
Release Date : 2021-08-19
Cutting Edge Approaches For Cns Protection And Repair Focus On Vascular And Degenerative Disorders written by Johannes Boltze and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-19 with Science categories.