The Science Of Alzheimer S Disease
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Time The Science Of Alzheimer S
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Author : Editors of TIME
language : en
Publisher: Time Home Entertainment
Release Date : 2019-07-08
Time The Science Of Alzheimer S written by Editors of TIME and has been published by Time Home Entertainment this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-08 with Health & Fitness categories.
Confusing, mysterious and unknown, Alzheimer's is among the most-feared diseases because it strikes indiscriminately and there is no known cure. Now, in The Science of Alzheimer's, a new Special Edition from the editors of TIME, we draw back the curtain to reveal the latest research on what the disease is and what it is not, and how science is working to make Alzheimer's a manageable problem with a hopeful long-term prognosis, akin to diabetes or HIV. Go inside the latest research on different types of dementia, hereditary and environmental causes, new treatments, and more. Helpful lifestyle tips show how to ward off mental decline as we age, and case histories-including the stories of musician Glen Campbell and President Ronald Reagan, who bravely shared their diagnoses with the world-reveal the human face of Alzheimer's. We also look at the latest drugs being used to treat the disease and how there is hope in recent treatments and protocols, as well as alternative treatments that may be making a difference. Packed with authoritative information from the health editors at TIME, this guide helps everyone understand a frightening disease-and recognize the strides that are being made to fight it.
Alzheimer S Disease Decoded The History Present And Future Of Alzheimer S Disease And Dementia
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Author : Ronald Sahyouni
language : en
Publisher: World Scientific
Release Date : 2016-10-06
Alzheimer S Disease Decoded The History Present And Future Of Alzheimer S Disease And Dementia written by Ronald Sahyouni and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-10-06 with Medical categories.
The book aims to present, educate and inform individuals about Alzheimer's disease in a comprehensive manner. Its scope ranges from the discovery of the disease, epidemiology and basic biological principles underlying it, to advanced stem cell therapies used in the treatment of Alzheimer's. It adopts a 'global' perspective on Alzheimer's disease, and include epidemiological data and science from countries around the world.Alzheimer's disease is a rapidly growing problem seen in every country around the world. This is the first and only comprehensive book to cover Alzheimer's disease, and includes the most updated literature and scientific progress in the field of dementia and Alzheimer's disease research.Most books on the market that focus on Alzheimer's disease are targeted at caregivers as practical advice on how to deal with loved ones with the disease. This book instead is a comprehensive and popular science book that can be read by anyone with an interest in learning more about the disease.Dr. Jefferson Chen MD, PhD, co-author, participated in the world's first surgical clinical trial using shunts to treat Alzheimer's disease. His first-hand involvement in a clinical trial for patients with Alzheimer's disease and experience treating Normal Pressure Hydrocephalus (NPH) which is commonly misdiagnosed as Alzheimer's disease lends a unique perspective.This book with appeal to a wide audience, regardless of their scientific or educational background.
Alzheimer S Disease
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Author : Ahmed Moustafa
language : en
Publisher: Academic Press
Release Date : 2021-08-28
Alzheimer S Disease written by Ahmed Moustafa and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-28 with Medical categories.
Nearly 44 million people have Alzheimer’s or related dementia worldwide, according to the Alzheimer’s Disease International organization. That number is expected to double every 20 years. Unlike other books on the market, Alzheimer's Disease: Understanding Biomarkers, Big Data, and Therapy covers recent advancements in cognitive, clinical, neural, and therapeutic aspects of Alzheimer’s and other forms of dementia. First, readers are introduced to cognitive and clinical studies, focusing on the different types of memory impairment, past and future thinking. This includes the prevalence of depression, its relationship to other symptoms, and the quality of life for those with Alzheimer’s disease. In addition, the book discusses recent studies on memory dysfunction in advanced-stage Alzheimer’s disease, in comparison to early-stage, including a chapter on the underlying factors in the transition from mild cognitive impairment to Alzheimer’s diagnosis. Following this section, the book presents recent studies on the role of different cortical and subcortical structures in the development of various symptoms in Alzheimer’s disease, as well as different neural biomarkers underlying the development and treatment of the disease. In the last section of the book, therapeutic aspects of Alzheimer’s disease, focusing on behavioral and pharmacological treatments of sleep disorders, memory problems, and depression, are reviewed. The book aids readers in understanding the advances in research and care, making it a prime tool for all clinicians, psychologists, researchers, neurologists, and caregivers of dementia patients. Reviews recent developments of cognitive and clinical studies Covers factors underlying the transition from mild cognitive impairment to Alzheimer’s disease Discusses different neural biomarkers underlying the development and treatment of Alzheimer’s disease Provides a comparison of the effectiveness of various types of treatments
The Alzheimer S Project
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Author : John Hoffman
language : en
Publisher: Hachette UK
Release Date : 2009-05-12
The Alzheimer S Project written by John Hoffman and has been published by Hachette UK this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-05-12 with Health & Fitness categories.
This companion book to the HBO Documentary Films series explores the cutting-edge research on Alzheimer's disease that is creating new hope for the future. Alzheimer's disease is the second most-feared illness in America, following cancer. It affects as many as 5 million Americans, a number that could soar to 16 million by 2050. It is estimated that, unless effective preventions are discovered, 10 million baby boomers will eventually develop this irreversible and devastating brain disorder. Until recently, medical news on Alzheimer's disease was not comforting. But in the past few years, advances in many scientific areas -- from diagnostic imaging to genetic analysis -- have led to an explosion of knowledge with implications for treatment and prevention. This is an exciting time of discovery in Alzheimer's research. Through The Alzheimer's Project film series, HBO Documentary Films illuminates the vital breakthroughs occurring in the field. One of the central films in this series, Momentum in Science, brings us inside the laboratories and clinics of the nation's top scientists and physicians who are clearing the path to a deeper understanding of Alzheimer's disease. By capturing the exhilaration of these scientists and casting light on their groundbreaking discoveries, the film seeks to bring a wider understanding of the disease and new hope for future treatment. This book offers an even closer look at the advances of this scientific frontier. It investigates the complex cascade of events that occurs inside the brain when someone has Alzheimer's disease and shows how scientists are working to interrupt this process and ultimately prevent the disease. In accessible prose, it examines specific evidence of momentous progress, from the triumphant discovery of the unique role of the beta-amyloid and tau proteins, to the use of PET scans to track changes in the brain and the analyses of cerebrospinal fluid to identify biomarkers that will help us predict who will develop the disease in the future. It also looks at current drug development and at what we can do as individuals to potentially reduce our risk of developing the disease. The Alzheimer's Project: Momentum in Science is a fascinating story of scientific discovery that shows what recent breakthroughs might mean for improving our chances of remaining cognitively vital throughout a long life.
Alzheimer S Disease A Century Of Scientific And Clinical Research
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Author : G. Perry
language : en
Publisher: IOS Press
Release Date : 2006-06-26
Alzheimer S Disease A Century Of Scientific And Clinical Research written by G. Perry and has been published by IOS Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-06-26 with Medical categories.
This publication is a landmark work commemorating the centennial of Alois Alzheimer's discovery of what would be known as Alzheimer's disease (AD). The centennial of Alois Alzheimer’s original description of the disease that would come to bear his name offers a vantage point from which to commemorate the seminal discoveries in the field. It traces how the true importance of AD as the major cause of late life dementia ultimately came to light and narrates the evolution of the concepts related to AD throughout the years and its recognition as a major public health problem, with an estimated 30-40 million people affected by AD today. To identify the breakthroughs, the editors have used citation analysis, landmark papers identified by current researchers, and drew upon their own experience and insights. This process took into account the perspectives of individuals who recall the impact of findings at the time they were made, as well as of scientists today who have the advantage of hindsight in weighing the lasting influence of these findings. Because modern AD research was triggered by the seminal work of Tomlinson, Blessed, and Roth some four decades ago, it is particularly fortunate that the vast majority of these milestone authors are still with us.
The Science Of Alzheimer S Disease
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Author : Applied Research Press
language : en
Publisher: Createspace Independent Pub
Release Date : 2014-11-14
The Science Of Alzheimer S Disease written by Applied Research Press and has been published by Createspace Independent Pub this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-11-14 with Medical categories.
Connecting minds with knowledge. With its acclaimed authors, cutting-edge content, emphasis on medical relevance, and coverage based on landmark research, The Science of Alzheimer's Disease has earned an impeccable reputation as an authoritative and exciting curated research journal and learning aid, perfect for students, medical professionals and other sophisticated readers. Hundreds of hours were spent compiling and editing this volume such that its readers are conveniently brought up-to-speed on the subject, presenting many of the latest and most important developments in the field. This volume presents 25 cutting-edge research papers on Alzheimer's, curated by our experts for maximal significance. Articles include: Advances in the pathogenesis of Alzheimer's disease: a re-evaluation of amyloid cascade hypothesis; Advances in the Pathogenesis of Alzheimer's Disease: Focusing on Tau-Mediated Neurodegeneration; Microglia receptors and their implications in the response to amyloid beta for Alzheimer's disease pathogenesis; Neurovascular dysfunction, inflammation and endothelial activation: Implications for the pathogenesis of Alzheimer's disease; Inflammation in Alzheimer's disease: relevance to pathogenesis and therapy; Vascular risk factors and Alzheimer's disease; Treatment of vascular risk factors in patients with a diagnosis of Alzheimer's disease: a systematic review; Inconsistencies and Controversies Surrounding the Amyloid Hypothesis of Alzheimer's Disease; A systematic review of cognitive decline in dementia with Lewy bodies versus Alzheimer's disease; Elevation of brain magnesium prevents synaptic loss and reverses cognitive deficits in Alzheimer's disease mouse model; Amyloid Beta and Tau Alzheimer's disease related pathology is reduced by Toll-like receptor 9 stimulation; Moving beyond anti-amyloid therapy for the prevention and treatment of Alzheimer's disease; Treatment effects in multiple cognitive domains in Alzheimer's disease: a two-year cohort study; First-in-man tau vaccine targeting structural determinants essential for pathological tau–tau interaction reduces tau oligomerisation and neurofibrillary degeneration in an Alzheimer's disease model; A diagnostic scale for Alzheimer's disease based on cerebrospinal fluid biomarker profiles; Epigenetic regulation of adult neural stem cells: implications for Alzheimer's disease; and many more.
Alzheimer S Disease
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Author : Amy Borenstein
language : en
Publisher: Academic Press
Release Date : 2016-02-16
Alzheimer S Disease written by Amy Borenstein and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-02-16 with Psychology categories.
Alzheimer's Disease: Lifecourse Perspectives on Risk Reduction summarizes the growing body of knowledge on the distribution and causes of Alzheimer’s disease (AD) in human populations, providing the reader with knowledge on how we define the disease and what its risk and protective factors are in the context of a life-course approach. At the conclusion of the book, the reader will understand why Alzheimer’s disease likely begins at conception, then progresses through early-life and adult risk factors that ultimately impact the balance between pathologic insults in the brain and the ability of the brain to modify disease symptoms. In contrast to edited volumes that may have little cohesion, this book focuses on an integrated life-course approach to the epidemiology of dementia, in particular, Alzheimer’s disease. Reviews the current science surrounding Alzheimer’s disease Provides a primer of foundational knowledge on the disease's epidemiology and biostatistics Utilizes a life-course approach, providing a novel and integrated view of the evolution of this illness from genes to brain reserve Uses the ‘threshold model’—a theory first described by Dr. Mortimer and widely accepted today—which incorporates the idea of risk factors for the pathology and expression of the disease Proposes that improving brain health through modifiable behaviors can delay disease onset until a later age Examines the future of prevention of Alzheimer’s disease, a subject of great current interest
Alzheimer S Disease Decoded The History Present And Future Of Alzheimer S Disease And Dementia Second Edition
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Author : Ronald Sahyouni
language : en
Publisher: World Scientific
Release Date : 2021-12-23
Alzheimer S Disease Decoded The History Present And Future Of Alzheimer S Disease And Dementia Second Edition written by Ronald Sahyouni and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-23 with Medical categories.
This book aims to present, educate and inform individuals about Alzheimer's disease in a comprehensive manner. Its scope ranges from the discovery of the disease, epidemiology and basic biological principles underlying it, to advanced stem cell therapies used in the treatment of Alzheimer's. It adopts a 'global' perspective on Alzheimer's disease, and include epidemiological data and science from countries around the world.Alzheimer's disease is a rapidly growing problem seen in every country around the world. This is the first and only comprehensive book to cover Alzheimer's disease, and includes the most updated literature and scientific progress in the field of dementia and Alzheimer's disease research.Most books on the market that focus on Alzheimer's disease are targeted at caregivers as practical advice on how to deal with loved ones with the disease. This book instead is a comprehensive and popular science book that can be read by anyone with an interest in learning more about the disease.Dr Jefferson Chen MD, PhD, co-author, participated in the world's first surgical clinical trial using shunts to treat Alzheimer's disease. His first-hand involvement in a clinical trial for patients with Alzheimer's disease and experience treating Normal Pressure Hydrocephalus (NPH) which is commonly misdiagnosed as Alzheimer's disease lends a unique perspective.This book with appeal to a wide audience, regardless of their scientific or educational background.
Aluminium And Alzheimer S Disease
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Author : C. Exley
language : en
Publisher: Elsevier
Release Date : 2001-07-03
Aluminium And Alzheimer S Disease written by C. Exley and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-07-03 with Science categories.
The subject of aluminium and Alzheimer's disease has been plagued with controversy. This controversy has served to obscure much of the scientific research in this field, and subsequently has obscured the possibility that aluminium is a contributory factor in the aetiology of Alzheimer's disease. This book brings together many of the world's leading scientists researching aluminium and life and contains their critical summaries on the known facts about aluminium toxicity in man and to offer an opinion on the implications of this knowledge on a link between aluminium and Alzheimer's disease. The subject areas of the chapters were chosen to reflect the myriad of ways that aluminium is known to impact upon mammalian physiology and function and range from clinical studies, through animal models of disease to the detailed biochemistry of aluminium toxicity. Chapters are also included on epidemiology and other factors involved in the aetiology of Alzheimer's.This is the first time that this subject has been treated in such a comprehensive manner. The research detailed in each chapter, includes the latest research in the field, it has been critically appraised and this appraisal has been used by each author to present an informed opinion of its relevance to aluminium and Alzheimer's disease. The chapters are much more than reviews; they are a statement of the state of the art and of what the future may hold for research in this field. As a whole they show the high quality of research that has been carried out in our efforts to understand the toxicity of aluminium in man and that we are far away from discounting the possibility that aluminium is a contributory factor in the aetiology of Alzheimer's disease.
How Not To Study A Disease
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Author : Karl Herrup
language : en
Publisher: MIT Press
Release Date : 2023-03-07
How Not To Study A Disease written by Karl Herrup and has been published by MIT Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-07 with Health & Fitness categories.
An authority on Alzheimer's disease offers a history of past failures and a roadmap that points us in a new direction in our journey to a cure. For decades, some of our best and brightest medical scientists have dedicated themselves to finding a cure for Alzheimer's disease. What happened? Where is the cure? The biggest breakthroughs occurred twenty-five years ago, with little progress since. In How Not to Study a Disease, neurobiologist Karl Herrup explains why the Alzheimer's discoveries of the 1990s didn't bear fruit and maps a direction for future research. Herrup describes the research, explains what's taking so long, and offers an approach for resetting future research. Herrup offers a unique insider's perspective, describing the red flags that science ignored in the rush to find a cure. He is unsparing in calling out the stubbornness, greed, and bad advice that has hamstrung the field, but his final message is a largely optimistic one. Herrup presents a new and sweeping vision of the field that includes a redefinition of the disease and a fresh conceptualization of aging and dementia that asks us to imagine the brain as a series of interconnected "neighborhoods." He calls for changes in virtually every aspect of the Alzheimer's disease research effort, from the drug development process, to the mechanisms of support for basic research, to the often-overlooked role of the scientific media, and more. With How Not to Study a Disease, Herrup provides a roadmap that points us in a new direction in our journey to a cure for Alzheimer's.