The Search For An Ideal Serm
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The Search For An Ideal Serm
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Author : Rachel G.C. Yahn
language : en
Publisher:
Release Date : 2014
The Search For An Ideal Serm written by Rachel G.C. Yahn and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with categories.
Climacteric Medicine Where Do We Go
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Author : Hermann P.G. Schneider
language : en
Publisher: CRC Press
Release Date : 2004-09-22
Climacteric Medicine Where Do We Go written by Hermann P.G. Schneider and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-09-22 with Medical categories.
At a time when ongoing research and clinical investigation into the use of HRT in perimenopausal women are incomplete--and when certain controversies remain unresolved--this summary of current opinion and knowledge fills the need for authoritative reference on this topic. Written by a 'Blue Ribbon' panel, the book addresses the wide range of advanc
Comprehensive Biomarker Discovery And Validation For Clinical Application
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Author : Péter Horvatovich
language : en
Publisher: Royal Society of Chemistry
Release Date : 2013
Comprehensive Biomarker Discovery And Validation For Clinical Application written by Péter Horvatovich and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with Medical categories.
This book covers proteomics biomarker discovery and validation procedures from the clinical perspective.
Post Menopausal Osteoporosis
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Author : Meeta
language : en
Publisher: JP Medical Ltd
Release Date : 2013-04-30
Post Menopausal Osteoporosis written by Meeta and has been published by JP Medical Ltd this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-30 with Health & Fitness categories.
Osteoporosis is one of the most common bone disorders, characterised by weakened bones and resulting in increased chances of fractures. This book begins with an overview of the disorder and continues with discussion on pathogenesis, epidemiology and genetic factors. The effects of menopause and aging on bone health, as well as identifying risk factors contributing to fractures, are examined. The following sections discuss management of osteoporosis including surgery and non-pharmacologic and lifestyle approaches to reducing the risk of fractures. With contributions from specialists in the UK, Italy, USA, New Zealand and India, this practical guide includes 50 images and illustrations to assist learning. Key points: Practical guide to the causes, diagnosis, treatment and management of osteoporosis Covers non-pharmacologic and lifestyle approaches to reduce risk of fractures Contributions from specialists in the UK, Italy, USA, new Zealand and India Includes 50 images and illustrations
Lost In Translation
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Author : Rakesh K. Srivastava
language : en
Publisher: World Scientific
Release Date : 2014
Lost In Translation written by Rakesh K. Srivastava and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with Medical categories.
This book is all about the definition and finding ways to prioritize and accelerate translation research in biomedical sciences and rapidly turning new knowledge into first-in-human studies. It represents an effort to bring together scientists active in various areas of translational research to share science and, hopefully, generate new ideas and potential collaborations. The book provides a comprehensive overview of translational work that includes significant discoveries and pioneering contributions, e.g., in immunology, gene therapy, stem cells and population sciences. It may be used as an advanced textbook by graduate students and even ambitious undergraduates in biomedical sciences. It is also suitable for non-experts, i.e. medical doctors, who wish to have an overview of some of the fundamental models in translational research. Managing the translational enterprise remains a work in progress. The world is changing rapidly, and the scientific world needs to seek new ways to ensure that discoveries get translated for patients efficiently and as quickly as possible. In addition, everyone expects the investment in biomedical research should pay dividends through effective therapeutic solutions. This unique project provides a broad collaborative approach of the international scientific team to present its view and opinion how to cross barriers to incentives for translational research in medical sciences. Contributing to the book is an international team of prominent co-authors. The book consists of unique and widely treated topics, and includes new hypotheses, data and analyses. Sample Chapter(s). Foreword (41 KB). Chapter 1: Translational Research: Lost in Complexity (305 KB). Contents: Barriers to Incentives for Translational Research; Integrating Emerging Science into Clinical Practice; Organization, Prioritization, Review and Funding for the Translational Research; Translational Sciences in Cancer Research; Translational Science in Infectious Diseases; Translation Research in Endocrinology and Nutrition; Translation Research and Neuroscience; Stem Cells and Translation Research; The Role of Translational Research in Public Health and Behavioral Sciences; Translational Epidemiology, Biostatistics and Informatics; Translational Research Outcomes and Resources. Readership: Graduate students and researchers in cancer research, pharmacology/drug discovery/pharmaceuticals, immunology, infectious diseases and public health.
Osteosarcopenia Bone Muscle And Fat Interactions
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Author : Gustavo Duque
language : en
Publisher: Springer Nature
Release Date : 2019-11-06
Osteosarcopenia Bone Muscle And Fat Interactions written by Gustavo Duque and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-06 with Science categories.
This edited work presents the most current evidence on osteosarcopenia from bench to bedside, which is expected to facilitate the understanding of this syndrome and to develop preventive and therapeutic strategies. With our aging population, chronic diseases such as osteoporosis and sarcopenia are becoming highly prevalent. Fortunately, our understanding of the bone and muscle interactions has increased in recent years. This has allowed to the coining of the term osteosarcopenia to describe a syndrome in which these two diseases overlap. This overlap between osteoporosis and sarcopenia has major negative effects not only on our older adults but also on health systems worldwide. Readers will find a highly translational approach that starts with a summary of recent discoveries on stem cells biology, muscle and bone interactions – including the role of local bone and muscle fat – followed by comprehensive reviews on myokines (i.e. myostatin), osteokines (i.e. osteocalcin) and adipokines (i.e. interleukins) as major players and determinants of bone and muscle loss with aging. In addition, the role of sex steroids (i.e. estrogens, androgens), and calciotropic hormones (i.e. parathyroid hormone, vitamin D) in the pathogenesis of this syndrome is also reviewed. Moreover, using practical diagnostic and therapeutic tips, this book summarizes the clinical characteristics of osteosarcopenic patients thus facilitating the diagnosis and treatment of this syndrome in clinical practice. Finally, the book presents the case for the Falls and Fractures Clinic as the optimal model of care for this syndrome, aimed to avoid fragmentation and optimize osteosarcopenia care, and simultaneously prevent falls and fractures in older persons. This book offers relevant information on the mechanisms of osteosarcopenia, and a practical guide on how to identify and treat this geriatric syndrome and its adverse outcomes, which are dramatically affecting our aging population. The work is written by leaders in the field and is especially suited not only to any researcher in the musculoskeletal arena but also to medical specialists and allied health professionals involved in the care of older persons.
Danforth S Obstetrics And Gynecology
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Author : Ronald S. Gibbs
language : en
Publisher: Lippincott Williams & Wilkins
Release Date : 2008
Danforth S Obstetrics And Gynecology written by Ronald S. Gibbs and has been published by Lippincott Williams & Wilkins this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Medical categories.
A core reference for residents and practitioners for more than 40 years, this volume has been thoroughly revised and reorganized to provide complete, authoritative coverage of the modern clinical practice of obstetrics and gynecology.
Chemo Fog
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Author : Robert B. Raffa
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-01-11
Chemo Fog written by Robert B. Raffa and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-01-11 with Medical categories.
Cancer patients have benefitted greatly from recent advances in the drugs, dose regimens, and combinations used to treat their primary tumor and for the treatment or prevention of spread of their disease. Due to the advances in chemotherapy and other aspects of prevention, early detection, and treatment modalities, an increasing percentage of patients are surviving the disease. For some types of cancer, the majority of patients live decades beyond their diagnosis. For this they are forever thankful and appreciative of the drugs that helped lead to this increased survival rate. But no drug is devoid of adverse effects. This also applies to chemotherapeutic agents. The acute cytotoxic effects of these agents are well known––indeed are often required for their therapeutic benefit. The chronic adverse effects are varied and in some cases less well known. With the increase in survival rates, there has emerged a new awareness of these chronic adverse effects.
Hormone Receptors In Breast Cancer
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Author : Suzanne A. W. Fuqua
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-12-10
Hormone Receptors In Breast Cancer written by Suzanne A. W. Fuqua and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-12-10 with Medical categories.
Hormone Receptors in Breast Cancer provides an up-to-date resource of the role of hormone receptors in breast cancer written in depth for both the basic molecular academic researcher and translational scientist. Advances in basic science of molecular endocrinology have undoubtedly been translated into clinical practice, and clinicians caring for this disease need to be knowledgeable about these developments. The molecular basis of hormone action has been elucidated, and the relative significance of the different estrogen and progesterone receptor isoforms has been explored. This explosion of information has lead to exciting new areas of gene specific targeting of the disease, and breast cancer prevention. Paradigm shifts in treatment options and sequencing have recently occurred in breast cancer management, necessitating close cooperation and communication between translational scientists and physicians. This book is focused on providing this communication.
Tamoxifen
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Author : Philipp Y. Maximov
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-07-23
Tamoxifen written by Philipp Y. Maximov and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-07-23 with Medical categories.
Tamoxifen is a pioneering medicine for the treatment and prevention of breast cancer. It is the first drug targeted therapy in cancer to be successful. Tamoxifen targets the tumor estrogen receptor. The therapy is known to have saved the lives of millions of women over the past 40 years. This monograph, written by V. Craig Jordan - known as the “father of tamoxifen” - and his Tamoxifen Team at the Georgetown University Washington DC, illustrates the journey of this milestone in medicine. It includes a personal interview with V. Craig Jordan about his four decades of discovery in breast cancer research and treatment. V. Craig Jordan was there for the birth of tamoxifen as he is credited for reinventing a “failed morning after contraceptive” to become the “gold standard” for the treatment of breast cancer. He contributed to every aspect of tamoxifen application in therapeutics and all aspects of tamoxifen’s pharmacology. He discovered the selective estrogen receptor modulators (SERMs) and explored the new biology of estrogen-induced apoptosis.