Tamoxifen
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Long Term Tamoxifen Treatment For Breast Cancer
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Author : Virgil Craig Jordan
language : en
Publisher: Univ of Wisconsin Press
Release Date : 1994
Long Term Tamoxifen Treatment For Breast Cancer written by Virgil Craig Jordan and has been published by Univ of Wisconsin Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with Breast categories.
During the past twenty years tamoxifen has become the most widely prescribed and most successful drug used in the treatment of breast cancer. In this volume, editor V. Craig Jordan provides articles that trace the development, pharmacology, and clinical research surrounding this drug which, by the year 2000, could be used to treat as many as one million women annually. Drawing from research conducted by specialists in the United States, the United Kingdom, and Italy, the series of articles describes the clinical testing of tamoxifen, highlighting the benefits. Studies show that tamoxifen lowers cholesterol and can potentially protect women against osteoporosis and fatal coronary heart disease. Equally important is a discussion of side effects and possible drug interactions and how these issues relate to patient concerns. An investigation of the development of a new class of drugs for use after tamoxifen fails provides valuable insight into future treatments, as the contributers consider possible resistance to tamoxifen. This volume provides invaluable information for physicians and surgeons who care for patients with breast cancer and for women interested in exploring this therapeutic dimension.
Tamoxifen
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Author : Philipp Y. Maximov
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-07-23
Tamoxifen written by Philipp Y. Maximov and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-07-23 with Medical categories.
Tamoxifen is a pioneering medicine for the treatment and prevention of breast cancer. It is the first drug targeted therapy in cancer to be successful. Tamoxifen targets the tumor estrogen receptor. The therapy is known to have saved the lives of millions of women over the past 40 years. This monograph, written by V. Craig Jordan - known as the “father of tamoxifen” - and his Tamoxifen Team at the Georgetown University Washington DC, illustrates the journey of this milestone in medicine. It includes a personal interview with V. Craig Jordan about his four decades of discovery in breast cancer research and treatment. V. Craig Jordan was there for the birth of tamoxifen as he is credited for reinventing a “failed morning after contraceptive” to become the “gold standard” for the treatment of breast cancer. He contributed to every aspect of tamoxifen application in therapeutics and all aspects of tamoxifen’s pharmacology. He discovered the selective estrogen receptor modulators (SERMs) and explored the new biology of estrogen-induced apoptosis.
Tamoxifen And Breast Cancer
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Author : Michael W. DeGregorio
language : en
Publisher: Yale University Press
Release Date : 1999-01-01
Tamoxifen And Breast Cancer written by Michael W. DeGregorio and has been published by Yale University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-01-01 with Medical categories.
A discussion of the diagnosis of breast cancer and the risks, benefits and limitations of treatment alternatives, particularly tamoxifen. This edition contains information on developments in the use of tamoxifen, especially in the results of the Breast Cancer Prevention Trial.
Tamoxifen
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Author : John A. Kellen
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Tamoxifen written by John A. Kellen and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Tamoxifen has persisted as a widely accepted and administered drug for almost 25 years. Following the many scientific papers and books on the subject, it has remained a very intriguing substance. This, perhaps, is the reason for another monograph on Tamoxifen. It is regrettably true that overviews, even when up to date after exhaustive research - the shibboleth of our cultures -, rapidly lose relevance with the passage of time. Scientists can sometimes be pictured as deep sea divers, who plunge into the unknown in search of a hitherto unknown world. Their descent is exciting, but eventually they must come up for air and integrate their experiences with others who also had to resurface. This book intends to collect and, where possible, to collate recent, but sometimes seemingly unrelated information. To quote Stephane Mallarme: "Everything in the world exists to end up in a book". Even if this is a tad cynical, it might not be far from the truth. If a little knowledge is a dangerous commodity, one can also add - tongue in cheek - that a vast amount of knowledge can be truly hazardous. It is likely that what might seem as entangled data is confusing, especially for those satisfied with the comfortable interpretation of Tamoxifen as an antiestrogen which has long been found insufficient. The complexity of its mechanisms and effects defies simple explanations and may even seem capricious, but only because of our ignorance.
Tamoxifen
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Author : Virgil Craig Jordan
language : en
Publisher: Oncology Group
Release Date : 1996
Tamoxifen written by Virgil Craig Jordan and has been published by Oncology Group this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with Health & Fitness categories.
Tamoxifen Concepts And Cancer
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Author : Ramon Andrade de Mello
language : en
Publisher: Nova Biomedical Books
Release Date : 2013
Tamoxifen Concepts And Cancer written by Ramon Andrade de Mello and has been published by Nova Biomedical Books this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with Breast categories.
Tamoxifen was first approved in 1977 and up to now remains a noteworthy therapeutic weapon to treat mainly breast cancer. However, further considerations exist regarding the tamoxifen profile. This book discusses recent research and future perspectives in the tamoxifen field. The topics discussed include tamoxifen pharmacokinetics, pharmacodynamics, adverse effects, clinical indications, therapeutic drug monitoring, autophagy mechanisms, tamoxifen topical formulation and breast cancer risk prevention, the use of tamoxifen in an oestrogen-independent manner for various neoplasms (Hepatocellular carcinoma, renal cell carcinoma, high grade glioma), mechanisms of resistance, potential role of CYP2D6, tamoxifen and antidepressants interaction in a psychiatric view, obesity influence in tamoxifen treatment, electrical pulse-mediated tamoxifen delivery, and tamoxifen in melanoma treatment.
Tamoxifen Tales
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Author : V. Craig Jordan
language : en
Publisher: Academic Press
Release Date : 2022-01-12
Tamoxifen Tales written by V. Craig Jordan and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-12 with Business & Economics categories.
Tamoxifen Tales: Suggestions for Scientific Survival presents a case study describing the academic journey of teams behind major advances in medical sciences, highlighting lessons learned that are applicable to the next generation of scientists. This book provides a manual on the successful mentoring of young scientists, including stories describing how training experience shaped careers to become leaders in academia and the pharmaceutical industry. The book documents Professor V. Craig Jordan’s 50-year career in medical sciences that led to the discovery and development of Selective Estrogen Receptor Modulators (SERMs), which became the standard of women’s healthcare around the world. Additionally, it illustrates the versatility of a scientist with a commitment to serving societies. This important resource will be a useful and interesting book for established medical scientists, research mentors and advanced students wanting to chart a successful and impactful research career. Highlights lessons learned from the journey behind discovery science that are applicable to the scientific journey of the next generation of scientists Provides a manual on the successful mentoring of young scientists to become leaders in academia and the pharmaceutical industry Examines cancer treatment based on a personal determination to challenge at the frontiers of the science and to relate to personal life experience Includes references for further research reading
Tamoxifen
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Author : Helen Wiseman
language : en
Publisher:
Release Date : 1994
Tamoxifen written by Helen Wiseman and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with Medical categories.
Currently there is considerable interest in the uses of tamoxifen not only to treat breast cancer but also to prevent it. Its potential as a major chemopreventative agent has attracted controversy relating to the possible harmful side-effects of tamoxifen therapy but also to its potential to protect against other cancers, cardiovascular disease and osteoporosis. This book explains the molecular basis of the action of tamoxifen, knowledge of which is vital to the understanding of its present uses and future potential, particularly in relation to the development of new derivatives. The book is a fully integrated, extensively referenced account of a wide range of topics relevent to the clinical use of tamoxifen, providing a comprehensive guide for those working in clinical and biomedical research within the pharmaceutical industry and in the fields of biochemistry, pharmacology, nutrition, oncology, toxicology, molecular and cellular biology, pharmacy, and obstetrics and gynaecology. The book’s readable also makes it accessible to medical practitioners and students of medicine and biology.
Advances In Tamoxifen Research And Application 2011 Edition
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Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2012-01-09
Advances In Tamoxifen Research And Application 2011 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-09 with Medical categories.
Advances in Tamoxifen Research and Application: 2011 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Tamoxifen in a concise format. The editors have built Advances in Tamoxifen Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Tamoxifen in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Tamoxifen Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Cancer Etiology Diagnosis And Treatments
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Author : Ramon Andrade De Mello
language : en
Publisher: Nova Science Publishers
Release Date : 2012
Cancer Etiology Diagnosis And Treatments written by Ramon Andrade De Mello and has been published by Nova Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Breast categories.
Tamoxifen was first approved in 1977 and up to now remains a noteworthy therapeutic weapon to treat mainly breast cancer. However, further considerations exist regarding the tamoxifen profile. This book discusses recent research and future perspectives in the tamoxifen field. The topics discussed include tamoxifen pharmacokinetics, pharmacodynamics, adverse effects, clinical indications, therapeutic drug monitoring, autophagy mechanisms, tamoxifen topical formulation and breast cancer risk prevention, the use of tamoxifen in an estrogen-independent manner for various neoplasms (Hepatocellular carcinoma, renal cell carcinoma, high grade glioma), mechanisms of resistance, potential role of CYP2D6, tamoxifen and antidepressants interaction in a psychiatric view, obesity influence in tamoxifen treatment, electrical pulse-mediated tamoxifen delivery, and tamoxifen in melanoma treatment.