Tamoxifen Concepts And Cancer
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Tamoxifen Concepts And Cancer
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Author : Ramon Andrade de Mello
language : en
Publisher: Nova Biomedical Books
Release Date : 2013
Tamoxifen Concepts And Cancer written by Ramon Andrade de Mello and has been published by Nova Biomedical Books this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with Breast categories.
Tamoxifen was first approved in 1977 and up to now remains a noteworthy therapeutic weapon to treat mainly breast cancer. However, further considerations exist regarding the tamoxifen profile. This book discusses recent research and future perspectives in the tamoxifen field. The topics discussed include tamoxifen pharmacokinetics, pharmacodynamics, adverse effects, clinical indications, therapeutic drug monitoring, autophagy mechanisms, tamoxifen topical formulation and breast cancer risk prevention, the use of tamoxifen in an oestrogen-independent manner for various neoplasms (Hepatocellular carcinoma, renal cell carcinoma, high grade glioma), mechanisms of resistance, potential role of CYP2D6, tamoxifen and antidepressants interaction in a psychiatric view, obesity influence in tamoxifen treatment, electrical pulse-mediated tamoxifen delivery, and tamoxifen in melanoma treatment.
Cancer Etiology Diagnosis And Treatments
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Author : Ramon Andrade De Mello
language : en
Publisher: Nova Science Publishers
Release Date : 2012
Cancer Etiology Diagnosis And Treatments written by Ramon Andrade De Mello and has been published by Nova Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Breast categories.
Tamoxifen was first approved in 1977 and up to now remains a noteworthy therapeutic weapon to treat mainly breast cancer. However, further considerations exist regarding the tamoxifen profile. This book discusses recent research and future perspectives in the tamoxifen field. The topics discussed include tamoxifen pharmacokinetics, pharmacodynamics, adverse effects, clinical indications, therapeutic drug monitoring, autophagy mechanisms, tamoxifen topical formulation and breast cancer risk prevention, the use of tamoxifen in an estrogen-independent manner for various neoplasms (Hepatocellular carcinoma, renal cell carcinoma, high grade glioma), mechanisms of resistance, potential role of CYP2D6, tamoxifen and antidepressants interaction in a psychiatric view, obesity influence in tamoxifen treatment, electrical pulse-mediated tamoxifen delivery, and tamoxifen in melanoma treatment.
Endocrine Therapy Of Breast Cancer
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Author : Franco Cavalli
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Endocrine Therapy Of Breast Cancer written by Franco Cavalli and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Starting in 1986, the European School of Oncology has expanded its activities in postgraduate teaching, which consisted mainly of traditional disease-orientated courses, by promoting new educational initiatives. One of these is the cloister seminars, short meetings intended for highly qualified oncologists and dealing with specific, controversial aspects of clinical practice and research. Another is the institution of permanent study groups, also called task forces, where a limited number of leading experts are invited to meet once a year with the aim of defining the state of the art and possibly reaching a consensus on developments and treatment in specific fields of oncology. This series of ESO Monographs was designed with the specific purpose of disseminating the results of the most interesting of the seminars and study groups, and providing concise and updated reviews of the subjects discussed. It was decided to keep the layout very simple in order to keep costs to a minimum and make the monographs available in the shortest possible time, thus overcoming a common problem in medical literature: that of the material being outdated even before publication. Umberto Veronesi Chairman, Scientific Committee European School of Oncology Table of Contents How to Read this Monograph F.CAvALLI ......... . 1 Experimental Strategies for Studying the Development of Breast Cancer with Special Reference to Steroid Hormones, Growth Factors and Oncogenes R.J.B. KING . . . . . . . . . . . . . . . . . . . . . . . . .. . . . 5 . . .
Tamoxifen
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Author : John A. Kellen
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Tamoxifen written by John A. Kellen and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Tamoxifen has persisted as a widely accepted and administered drug for almost 25 years. Following the many scientific papers and books on the subject, it has remained a very intriguing substance. This, perhaps, is the reason for another monograph on Tamoxifen. It is regrettably true that overviews, even when up to date after exhaustive research - the shibboleth of our cultures -, rapidly lose relevance with the passage of time. Scientists can sometimes be pictured as deep sea divers, who plunge into the unknown in search of a hitherto unknown world. Their descent is exciting, but eventually they must come up for air and integrate their experiences with others who also had to resurface. This book intends to collect and, where possible, to collate recent, but sometimes seemingly unrelated information. To quote Stephane Mallarme: "Everything in the world exists to end up in a book". Even if this is a tad cynical, it might not be far from the truth. If a little knowledge is a dangerous commodity, one can also add - tongue in cheek - that a vast amount of knowledge can be truly hazardous. It is likely that what might seem as entangled data is confusing, especially for those satisfied with the comfortable interpretation of Tamoxifen as an antiestrogen which has long been found insufficient. The complexity of its mechanisms and effects defies simple explanations and may even seem capricious, but only because of our ignorance.
Tamoxifen
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Author : Philipp Y. Maximov
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-07-23
Tamoxifen written by Philipp Y. Maximov and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-07-23 with Medical categories.
Tamoxifen is a pioneering medicine for the treatment and prevention of breast cancer. It is the first drug targeted therapy in cancer to be successful. Tamoxifen targets the tumor estrogen receptor. The therapy is known to have saved the lives of millions of women over the past 40 years. This monograph, written by V. Craig Jordan - known as the “father of tamoxifen” - and his Tamoxifen Team at the Georgetown University Washington DC, illustrates the journey of this milestone in medicine. It includes a personal interview with V. Craig Jordan about his four decades of discovery in breast cancer research and treatment. V. Craig Jordan was there for the birth of tamoxifen as he is credited for reinventing a “failed morning after contraceptive” to become the “gold standard” for the treatment of breast cancer. He contributed to every aspect of tamoxifen application in therapeutics and all aspects of tamoxifen’s pharmacology. He discovered the selective estrogen receptor modulators (SERMs) and explored the new biology of estrogen-induced apoptosis.
Endocrine Therapy Of Breast Cancer Vi
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Author : Anthony Howell
language : en
Publisher: Springer
Release Date : 1994-04-26
Endocrine Therapy Of Breast Cancer Vi written by Anthony Howell and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-04-26 with Medical categories.
The European School of Oncology came into existence to respond to a need for information, education and training in the field of the diagnosis and treatment of cancer. There are two main reasons why such an initiative was considered necessary. Firstly, the teaching of oncology requires a rigorously multidisciplinary approach which is difficult for the Universities to put into practice since their system is mainly disciplinary orientated. Secondly, the rate of technological development that impinges on the diagnosis and treatment of cancer has been so rapid that it is not an easy task for medical faculties to adapt their curricula flexibly. With its residential courses for organ pathologies and the seminars on new techniques (laser, monoclonal antibodies, imaging techniques etc.) or on the principal therapeutic controversies (conservative or mutilating surgery, primary or adjuvant chemotherapy, radiotherapy alone or integrated), it is the ambition of the European School of Oncology to fill a cultural and scientific gap and, thereby, create a bridge between the University and Industry and between these two and daily medical practice. One of the more recent initiatives of ESO has been the institution of permanent study groups, also called task forces, where a limited number of leading experts are invited to meet once a year with the aim of defining the state of the art and possibly reaching a consensus on future developments in specific fields of oncology.
Tamoxifen
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Author : Helen Wiseman
language : en
Publisher:
Release Date : 1994
Tamoxifen written by Helen Wiseman and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with Medical categories.
Currently there is considerable interest in the uses of tamoxifen not only to treat breast cancer but also to prevent it. Its potential as a major chemopreventative agent has attracted controversy relating to the possible harmful side-effects of tamoxifen therapy but also to its potential to protect against other cancers, cardiovascular disease and osteoporosis. This book explains the molecular basis of the action of tamoxifen, knowledge of which is vital to the understanding of its present uses and future potential, particularly in relation to the development of new derivatives. The book is a fully integrated, extensively referenced account of a wide range of topics relevent to the clinical use of tamoxifen, providing a comprehensive guide for those working in clinical and biomedical research within the pharmaceutical industry and in the fields of biochemistry, pharmacology, nutrition, oncology, toxicology, molecular and cellular biology, pharmacy, and obstetrics and gynaecology. The book’s readable also makes it accessible to medical practitioners and students of medicine and biology.
Tamoxifen And Breast Cancer
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Author : Michael W. DeGregorio
language : en
Publisher: Yale University Press
Release Date : 1999-01-01
Tamoxifen And Breast Cancer written by Michael W. DeGregorio and has been published by Yale University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-01-01 with Medical categories.
A discussion of the diagnosis of breast cancer and the risks, benefits and limitations of treatment alternatives, particularly tamoxifen. This edition contains information on developments in the use of tamoxifen, especially in the results of the Breast Cancer Prevention Trial.
Tamoxifen For The Treatment And Prevention Of Breast Cancer
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Author : V. Craig Jordan
language : en
Publisher:
Release Date : 1999-01-01
Tamoxifen For The Treatment And Prevention Of Breast Cancer written by V. Craig Jordan and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-01-01 with categories.
Cancer Prevention And Screening
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Author : Rosalind A. Eeles
language : en
Publisher: John Wiley & Sons
Release Date : 2018-11-13
Cancer Prevention And Screening written by Rosalind A. Eeles and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-11-13 with Medical categories.
Winner of the Council Chair's Choice Award at the 2019 British Medical Association Awards. Cancer Prevention and Screening offers physicians and all clinical healthcare professionals a comprehensive, useful source of the latest information on cancer screening and prevention with both a global and a multidisciplinary perspective. Includes background information on epidemiology, cancer prevention, and cancer screening, for quick reference Offers the latest information for clinical application of the most recent techniques in prevention and screening of all major and many lesser cancer types Emphasises the importance of multidisciplinary teamwork in cancer screening Highlights frequent dilemmas and difficulties encountered during cancer screening Provides clear-cut clinical strategies for optimal patient education, communication, and compliance with cancer prevention techniques