The Somatotrophic Axis In Brain Function
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The Somatotrophic Axis In Brain Function
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Author : Fred Nyberg
language : en
Publisher: Elsevier
Release Date : 2005-12-12
The Somatotrophic Axis In Brain Function written by Fred Nyberg and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-12-12 with Medical categories.
The somatotropic axis is one of the major hormonal systems regulating postnatal growth in mammals. It interacts with the central nervous system on several levels. Growth hormone (GH) and insulin-like growth factor-I (IGF-I) receptors are expressed in many brain areas including the hippocampus, pituitary and hypothalamus. GH and IGF-I are important factors in the development and differentiation of the CNS and have protective properties in dementia, as well as in traumatic and ischaemic injury of the CNS. Also GH has an important impact on mood and well-being with GH secretory capacity being reduced in depression.This volume will include chapters (1) on basic knowledge on GH/IGF-1, (2) on localization of GH/IGF-1 and their receptors in the CNS, including blood brain barrier transport of both hormones, (3) on actions of the two hormones on CNS function (basic science), (4) on clinical aspects of GH/IGF-1 in relation to various CNS functions and disorders, and finally (5) on some future perspectives in this area of science.Contents are well balanced and cover a variety of relevant topics from basic to clinical researchInternational selection of authors, with a good representation of the research on growth hormonesA timely publication which will be useful to scientists in both basic and clinical research
New Concepts Of Psychostimulants Induced Neurotoxicity
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Author : Hari Shanker Sharma
language : en
Publisher: Academic Press
Release Date : 2009-11-05
New Concepts Of Psychostimulants Induced Neurotoxicity written by Hari Shanker Sharma and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-11-05 with Science categories.
Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. With recent advancements in new knowledge, it has become evident that psychostimulants and related drugs of abuse are influencing our central nervous system (CNS) remarkably and could alter their function for a longtime. This volume is the first to focus on substance abuse induced brain pathology in the widest sense as it covers alterations in neuronal, glial and endothelial cell functions under the influence of acute or chronic usage of substance abuse.
Traumatic Brain Injury
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Author : Mark J. Ashley
language : en
Publisher: CRC Press
Release Date : 2017-07-28
Traumatic Brain Injury written by Mark J. Ashley and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-07-28 with Medical categories.
The fourth edition of this text constitutes a continuation of 20 years of coverage of traumatic brain injury, and broadens the discussion of acquired brain injury. Within TBI, the paradigm shift from an injury occurring at a point in time to a disease entity of a chronic nature is changing the discussion of diagnosis, management, treatment and outcome assessment. Disease specification that differentiates TBIs by the mechanism of injury, the exact nature of the injury, the extent of injury, presence of co-morbidities and their exact nature, gender, age, race, and genome are emerging as crucial. Disease differentiation has impacted diagnosis, treatment and outcome.
Growth Hormone Therapy In Pediatrics 20 Years Of Kigs
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Author : M. B. Ranke
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2007-04-27
Growth Hormone Therapy In Pediatrics 20 Years Of Kigs written by M. B. Ranke and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-04-27 with Medical categories.
For 20 years, KIGS (Pfizer International Growth Database) has provided an outstanding tool for monitoring the use, efficacy and safety of growth hormone (GH) treatment in children with short stature of varying origin. This volume offers a comprehensive update of the continuing experiences in KIGS and is based on data from more than 50 countries and more than 60,000 patients. International experts analyse in detail the basic auxological characteristics of patients and their response to GH treatment for a broad spectrum of growth disorders. These include idiopathic GH deficiency, organic GH deficiency due to a variety of causes such as congenital malformations and syndromes, genetic disorders or treatment for leukaemia or central nervous system tumours and short stature in children born small for gestational age, specific syndromes and systemic disorders. Each growth disorder is also covered by a review of relevant published data by international experts. KIGS has also established itself as a primary source of information about adverse events during long-term GH treatment in children. The recent analysis of KIGS data has revealed no new adverse drug reactions since the 10-year follow-up. Therefore, treatment with GH seems a low-risk intervention in children and adolescents with various growth disorders. The process of developing disease-specific growth response prediction models has been ongoing in KIGS for many years. The available models are accurate, precise and have a relatively high degree of predictive power, although further predictors of the growth response remain to be identified. The KIGS prediction models can be applied prospectively to new patients, enabling their GH therapy to be better tailored and monitored to achieve optimal growth, safety and cost outcomes. The future of KIGS within the era of evidence-based medicine will continue to depend upon the quality of the data reported. Therefore, the commitment of participating physicians will continue to be a decisive element. The ongoing recognition of the importance of valid safety and efficacy information in the practice of paediatric endocrinology is exemplified by this valuable international collaboration of clinicians and the pharmaceutical community.
Handbook Of Models For Human Aging
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Author : P. Michael Conn
language : en
Publisher: Elsevier
Release Date : 2011-04-28
Handbook Of Models For Human Aging written by P. Michael Conn and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-04-28 with Medical categories.
The Handbook of Models for Human Aging is designed as the only comprehensive work available that covers the diversity of aging models currently available. For each animal model, it presents key aspects of biology, nutrition, factors affecting life span, methods of age determination, use in research, and disadvantages/advantes of use. Chapters on comparative models take a broad sweep of age-related diseases, from Alzheimer's to joint disease, cataracts, cancer, and obesity. In addition, there is an historical overview and discussion of model availability, key methods, and ethical issues. - Utilizes a multidisciplinary approach - Shows tricks and approaches not available in primary publications - First volume of its kind to combine both methods of study for human aging and animal models - Over 200 illustrations
Encyclopedia Of Obesity
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Author : Kathleen Keller
language : en
Publisher: SAGE
Release Date : 2008-01-24
Encyclopedia Of Obesity written by Kathleen Keller and has been published by SAGE this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-01-24 with Medical categories.
Obesity is a serious health issue and is a key discussion and research point in several disciplines from the social sciences to the health sciences and even in physical education. This text is a much-needed authoritative reference source covering major issues of, and relating to, obesity.
Exercise And Its Mediating Effects On Cognition
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Author : Waneen Wyrick Spirduso
language : en
Publisher: Human Kinetics
Release Date : 2007
Exercise And Its Mediating Effects On Cognition written by Waneen Wyrick Spirduso and has been published by Human Kinetics this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Medical categories.
This title seeks to expand on reader's understanding by examining whether and how physical activity could indirectly affect cognitive function by influencing mediators that provide physical and mental resources for cognition.
Mcqs In Endocrinology For Dm Entrance Examination
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Author : Amritava Ghosh
language : en
Publisher: Jaypee Brothers Medical Publishers
Release Date : 2019-09-30
Mcqs In Endocrinology For Dm Entrance Examination written by Amritava Ghosh and has been published by Jaypee Brothers Medical Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-30 with Medical categories.
1. Principles of Hormone Action 2. Genetics of Endocrinology 3. Laboratory Techniques for Recognition of Endocrine Disorders 4. Neuroendocrinology 5. Pituitary Physiology and Diagnostic Evaluation 6. Pituitary Masses and Tumors 7. Posterior Pituitary 8. Thyroid 9. Adrenal Cortex 10. Endocrine Hypertension 11. Female Reproductive Axis 12. Testicular Disorders 13. Multiple Endocrine Neoplasia 14. Endocrine Changes in Pregnancy 15. Endocrinology of Fetal Development 16. Pediatric Disorders of Sexual Development 17. Normal and Aberrant Growth 18. Puberty 19. Mineral Metabolism 20. Kidney Stones 21. Diabetes 22. Hypoglycemia 23. Obesity 24. Disorders of Lipid Metabolism 25. Statistics
Biology Of Brain Disorders
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Author : Daniela Tropea
language : en
Publisher: Frontiers Media SA
Release Date : 2018-01-31
Biology Of Brain Disorders written by Daniela Tropea and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-31 with categories.
Brain disorders, including neurological and neuropsychiatric conditions, represent a challenge for public health systems and society at large. The limited knowledge of their biology hampers the development of diagnostic tools and effective therapeutics. A clear understanding of the mechanisms that underlie the onset and progression of brain disorders is required in order to identify new avenues for therapeutic intervention. Overlapping genetic risk factors across different brain disorders suggest common linkages and pathophysiological mechanisms that underlie brain disorders. Methodological and technological advances are leading to new insights that go beyond traditional hypotheses. Taking account of underlying molecular, cellular and systems biology underlying brain function will play an important role in the classification of brain disorders in future. In this Research Topic, the latest advances in our understanding of biological mechanisms across different brain disorders are presented. The areas covered include developments in neurogenetics, epigenetics, plasticity, glial cell biology, neuroimmune interactions and new technologies associated with the study of brain function. Examples of how understanding of biological mechanisms are translating into research strategies that aim to advance diagnoses and treatment of brain disorders are discussed.
Advances In The Neurochemistry And Neuropharmacology Of Tourette Syndrome
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Author :
language : en
Publisher: Academic Press
Release Date : 2013-11-27
Advances In The Neurochemistry And Neuropharmacology Of Tourette Syndrome written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-27 with Medical categories.
This volume of International Review of Neurobiology brings together cutting-edge research on advances in the neurochemistry and neuropharmacology of Tourette syndrome. It reviews current knowledge and understanding, provides a starting point for researchers and practitioners entering the field, and includes important topics regards tics, neurotransmitters, pharmacology and emerging treatments. - This volume of brings together research on tourettes synrdrome. It reviews current knowledge and understanding on the neurochemistry and neuropharmacology of tourettes syndrome