The Specific Treatment Of Virus Diseases
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The Specific Treatment Of Virus Diseases
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Author : D.J. Bauer
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
The Specific Treatment Of Virus Diseases written by D.J. Bauer and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
In comparison with antibacterial chemotherapy the clinical use of specific antiviral drugs is a fairly recent development. By the 1950s a number had been discovered, but their clinical application was delayed until 1962, when methisazone was used for the treatment of infective complications of smallpox vaccination and idoxuridine in the treatment of herpetic keratitis. In retrospect the reasons for this slowness in development is now evident. It was due in large part to the prevailing view held at the time that virus infections could never be treated with specific agents, since the multiplica tion of virus is so closely integrated with the metabolic processes of the host cell that specificity of action seemed impossible of achievement. In contrast, bacteria were independent entities with metabolic systems differing widely from those of the mammalian host, which afforded points of attack by specific agents which had no action upon mammalian systems. Although the mode of action of the sulphonamides and penicillin was not known for some time, they afforded perfect examples of the success of this mode of attack.
The Specific Treatment Of Virus Diseases
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Author : Denis John Bauer
language : en
Publisher:
Release Date : 1977
The Specific Treatment Of Virus Diseases written by Denis John Bauer and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1977 with Antiviral agents categories.
Lennette S Laboratory Diagnosis Of Viral Infections
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Author : Keith R Jerome
language : en
Publisher: CRC Press
Release Date : 2016-04-19
Lennette S Laboratory Diagnosis Of Viral Infections written by Keith R Jerome and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-19 with Medical categories.
Written from the perspective of the diagnostician, this bestselling book is the definitive text on the laboratory diagnosis of human viral diseases. It contains a wealth of illustrations, tables, and algorithms to enhance your understanding of this ever-evolving field. The book is a ready reference for virologists, microbiologists, epidemiologists, laboratorians, and infections disease specialists, and students.
Viral Infections And Treatment
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Author : Helga Rübsamen-Waigmann
language : en
Publisher: CRC Press
Release Date : 2003-08
Viral Infections And Treatment written by Helga Rübsamen-Waigmann and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-08 with Medical categories.
Examining the pathology and transmission of the most common viral diseases, this reference compiles reviews by international specialists which detail breakthroughs in patient management, diagnostics and treatment of viral infections.
Viral Drug Delivery Systems
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Author : Ranjita Shegokar
language : en
Publisher: Springer Nature
Release Date : 2023-04-10
Viral Drug Delivery Systems written by Ranjita Shegokar and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-04-10 with Science categories.
The disability-adjusted life year (DALY) is a generic measure of health effect that can be used in cost-effectiveness analysis as an alternative to the quality-adjusted life year (QALY). Infectious diseases are one of the major to cause significant losses of DALY and QALY. Human infectious diseases are disorders that are triggered by the micro-organisms such as bacteria, fungi, viruses, or parasites. The majority of such diseases are contagious and create a public health menace. There are several reasons why infectious diseases are deadly diseases, and one of the primary reasons is the drug resistance developed over time. Drug resistance-associated mutations are linked to increasing drug efflux, modifications of the drugs, or their targets. Every year, new drugs are being approved by FDA to treat infectious diseases. Nonetheless, the infectious diseases will undoubtedly persist as permanent and main threats to humanity for now and in the future, primarily due to increased longevity that almost always comes at a cost of impaired immunity. A total of four books are covered under the series of Infectious drug diseases. - Malarial drug delivery systems - Tubercular drug delivery systems - Viral drug delivery systems - Infectious disease drug delivery systems The third volume of series is focused on viral drug delivery systems. Typically, virus attaches to the cells (referred as host cell) and releases its DNA or RNA inside the cell. In second stage, virus’s genetic material takes control of the cell and forces it to replicate the virus leading to onset of disease symptoms. DNA class of viruses include Herpes, Papilloma and Adeno viruses. RNA class of viruses include retroviruses, such as HIV immunodeficiency virus and SARS COV – 2 / Corona virus. This book addresses recent developments in viral drug delivery systems. It covers many different aspects of viral infections, ways to treat them using modern drug delivery systems like nano particulate carriers. The choice of viral delivery systems mainly depends upon the type of virus, duration of life cycle, presence of drug resistance, cellular and mucosal interaction of virus, accordingly gene or non-gene drug delivery systems are selected. Besides that, this book also reports global dynamics of viral diseases, future predictions of infection rate, current treatment options, details of drug carriers like nanoemulsions, polymeric nanoparticles, role of biofunctionalization, and phyto-molecules in treatment of viral infections particularly herpes, Covid-19, Ebola, HIV/AIDS, influenza and viral hepatitis. Audiences from a broad range of groups, from researchers, academicians, and public health bodies to regulatory experts, can benefit from the compiled information to learn more about patient needs and current research advances in the field of viral drug delivery research.
What You Need To Know About Infectious Disease
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Author : Madeline Drexler
language : en
Publisher:
Release Date :
What You Need To Know About Infectious Disease written by Madeline Drexler and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.
Chemotherapy Of Viral Infections
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Author : P E. Came
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Chemotherapy Of Viral Infections written by P E. Came and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
" . . . the motto for the therapeutics of the future will have to be de sedibus et causis pharmacorum. " P. EHRLICH, 1909 Exciting events in the basic disciplines of virology, immunology, and pharmacology continue to advance the understanding of the pathogenesis and control of virus diseases. At the same time, the rational development of antiviral agents is attracting, to an increasing extent, the interest of workers in other disciplines. Improvements in technology facilitate the definition of potential target sites for antiviral intervention and unmask new viral and host genes. The outcome is a further steady development of new antiviral agents which approach the "magic bullets" first proposed by PAUL EHRLICH. Remarkable advances in protein synthetic methods that yield polypeptides which inhibit active sites of viral proteins have aided substantially in the basic and clinical study of these antiviral agents. In addition, the extremely rapid progression in recombinant DNA techniques, leading to the synthesis of large quantities of gene products, is also increasing our opportunities at a dashing pace. New information and developing technology facilitate research on the mechanism of action, toxicity, pharmacokinetics, and pharmacodynamics of new agents. The list of clinically effective antiviral agents is expanding and the number of potentially useful compounds is growing rapidly. This book is a combined theoretical text and practical manual which, it is hoped, will be of use to all who have an interest in virus diseases, particularly scientists, physicians and graduate students.
Antiviral Chemotherapy
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Author : D. J. Jeffries
language : en
Publisher:
Release Date : 1995-07-11
Antiviral Chemotherapy written by D. J. Jeffries and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-07-11 with Medical categories.
Considerable advances have been made in the treatment of antiviral diseases over the last decade. Several new drugs have been introduced while new clinical information has been gathered on the efficacy of existing drugs. This study aims to provide an examination of the basic science (drug formulae, structure and biochemical activity) and clinical information (usage and efficacy) on chemotherapy, as well as describing future potentials.
Practical Guidelines In Antiviral Therapy
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Author : G.J. Galasso
language : en
Publisher: Elsevier
Release Date : 2002-01-21
Practical Guidelines In Antiviral Therapy written by G.J. Galasso and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-01-21 with Medical categories.
This text was developed with the practicing physician in mind, however, it will be of considerable interest to the virologist, pharmacologist, chemist and all scientists interested in antiviral agents. Progress in the field of antiviral development is now moving rapidly and there is hope that one day there will be successful treatment modalities for most viral diseases. This work contains contributions from experts around the world, capturing worldwide practices. An online version providing the current status of antiviral research is planned for the near future.
Gene Therapy For Viral Infections
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Author : Patrick Arbuthnot
language : en
Publisher: Academic Press
Release Date : 2015-06-01
Gene Therapy For Viral Infections written by Patrick Arbuthnot and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-06-01 with Science categories.
Gene Therapy for Viral Infections provides a comprehensive review of the broader field of nucleic acid and its use in treating viral infections. The text bridges the gap between basic science and important clinical applications of the technology, providing a systematic, integrated review of the advances in nucleic acid-based antiviral drugs and the potential advantages of new technologies over current treatment options. Coverage begins with the fundamentals, exploring varying topics, including harnessing RNAi to silence viral gene expression, antiviral gene editing, viral gene therapy vectors, and non-viral vectors. Subsequent sections include detailed coverage of the developing use of gene therapy for the treatment of specific infections, the principles of rational design of antivirals, and the hurdles that currently face the further advancement of gene therapy technology. Provides coverage of gene therapy for a variety of infections, including HBV, HCV, HIV, hemorrhagic fever viruses, and respiratory and other viral infections Bridges the gap between the basic science and the important medical applications of this technology Features a broad approach to the topic, including an essential overview and the applications of gene therapy, synthetic RNA, and other antiviral strategies that involve nucleic acid engineering Presents perspectives on the future use of nucleic acids as a novel class of antiviral drugs Arms the reader with the cutting-edge information needed to stay abreast of this developing field
