The Stockholm Paradigm
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The Stockholm Paradigm
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Author : Daniel R. Brooks
language : en
Publisher: University of Chicago Press
Release Date : 2019-07-19
The Stockholm Paradigm written by Daniel R. Brooks and has been published by University of Chicago Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-19 with Science categories.
The contemporary crisis of emerging disease has been a century and a half in the making. Human, veterinary, and crop health practitioners convinced themselves that disease could be controlled by medicating the sick, vaccinating those at risk, and eradicating the parts of the biosphere responsible for disease transmission. Evolutionary biologists assured themselves that coevolution between pathogens and hosts provided a firewall against disease emergence in new hosts. Most climate scientists made no connection between climate changes and disease. None of these traditional perspectives anticipated the onslaught of emerging infectious diseases confronting humanity today. As this book reveals, a new understanding of the evolution of pathogen-host systems, called the Stockholm Paradigm, explains what is happening. The planet is a minefield of pathogens with preexisting capacities to infect susceptible but unexposed hosts, needing only the opportunity for contact. Climate change has always been the major catalyst for such new opportunities, because it disrupts local ecosystem structure and allows pathogens and hosts to move. Once pathogens expand to new hosts, novel variants may emerge, each with new infection capacities. Mathematical models and real-world examples uniformly support these ideas. Emerging disease is thus one of the greatest climate change–related threats confronting humanity. Even without deadly global catastrophes on the scale of the 1918 Spanish Influenza pandemic, emerging diseases cost humanity more than a trillion dollars per year in treatment and lost productivity. But while time is short, the danger is great, and we are largely unprepared, the Stockholm Paradigm offers hope for managing the crisis. By using the DAMA (document, assess, monitor, act) protocol, we can “anticipate to mitigate” emerging disease, buying time and saving money while we search for more effective ways to cope with this challenge.
The Stockholm Paradigm
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Author : Daniel R. Brooks
language : en
Publisher: University of Chicago Press
Release Date : 2019-07-16
The Stockholm Paradigm written by Daniel R. Brooks and has been published by University of Chicago Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-16 with Science categories.
The contemporary crisis of emerging disease has been a century and a half in the making. Human, veterinary, and crop health practitioners convinced themselves that disease could be controlled by medicating the sick, vaccinating those at risk, and eradicating the parts of the biosphere responsible for disease transmission. Evolutionary biologists assured themselves that coevolution between pathogens and hosts provided a firewall against disease emergence in new hosts. Most climate scientists made no connection between climate changes and disease. None of these traditional perspectives anticipated the onslaught of emerging infectious diseases confronting humanity today. As this book reveals, a new understanding of the evolution of pathogen-host systems, called the Stockholm Paradigm, explains what is happening. The planet is a minefield of pathogens with preexisting capacities to infect susceptible but unexposed hosts, needing only the opportunity for contact. Climate change has always been the major catalyst for such new opportunities, because it disrupts local ecosystem structure and allows pathogens and hosts to move. Once pathogens expand to new hosts, novel variants may emerge, each with new infection capacities. Mathematical models and real-world examples uniformly support these ideas. Emerging disease is thus one of the greatest climate change–related threats confronting humanity. Even without deadly global catastrophes on the scale of the 1918 Spanish Influenza pandemic, emerging diseases cost humanity more than a trillion dollars per year in treatment and lost productivity. But while time is short, the danger is great, and we are largely unprepared, the Stockholm Paradigm offers hope for managing the crisis. By using the DAMA (document, assess, monitor, act) protocol, we can “anticipate to mitigate” emerging disease, buying time and saving money while we search for more effective ways to cope with this challenge.
The Atrocity Paradigm
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Author : Claudia Card
language : en
Publisher: Oxford University Press
Release Date : 2002-09-12
The Atrocity Paradigm written by Claudia Card and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-09-12 with Philosophy categories.
What distinguishes evils from ordinary wrongs? Is hatred a necessarily evil? Are some evils unforgivable? Are there evils we should tolerate? What can make evils hard to recognize? Are evils inevitable? How can we best respond to and live with evils?Claudia Card offers a secular theory of evil that responds to these questions and more. Evils, according to her theory, have two fundamental components. One component is reasonably foreseeable intolerable harm -- harm that makes a life indecent and impossible or that makes a death indecent. The other component is culpable wrongdoing. Atrocities, such as genocides, slavery, war rape, torture, and severe child abuse, are Card's paradigms because in them these key elements are writ large. Atrocities deserve more attention than secular philosophers have so far paid them. They are distinguished from ordinary wrongs not by the psychological states of evildoers but by the seriousness of the harm that is done. Evildoers need not be sadistic:they may simply be negligent or unscrupulous in pursuing their goals.Card's theory represents a compromise between classic utilitarian and stoic alternatives (including Kant's theory of radical evil). Utilitarians tend to reduce evils to their harms; Stoics tend to reduce evils to the wickedness of perpetrators: Card accepts neither reduction. She also responds to Nietzsche's challenges about the worth of the concept of evil, and she uses her theory to argue that evils are more important than merely unjust inequalities. She applies the theory in explorations of war rape and violence against intimates. She also takes up what Primo Levi called "the gray zone", where victims become complicit in perpetrating on others evils that threaten to engulf themselves. While most past accounts of evil have focused on perpetrators, Card begins instead from the position of the victims, but then considers more generally how to respond to -- and live with -- evils, as victims, as perpetrators, and as those who have become both.
Mobile Virtual Work
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Author : J.H. Erik Andriessen
language : en
Publisher: Springer Science & Business Media
Release Date : 2005-12-16
Mobile Virtual Work written by J.H. Erik Andriessen and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-12-16 with Business & Economics categories.
Dear Reader This is a book about mobile virtual work. It aims at clarifying the basic concepts and showing present practices and future challenges. The roots of the book are in the collaboration of few European practitioners and - searchers, who met each other under the umbrella of the Swedish SALTSA programme (see next page) in January 2002 in Stockholm. The group was first called ‘ICT, Mobility and Work Organisation’ but redefined itself quickly as ‘Mobile Virtual Cooperative Work’ group. The change of the name reflects the development of reasoning in the group. We could not find much material on mobile work, certainly not systematic studies, - though a growing interest in mobile technologies and services could be found. Practices of telework and virtual organizations were better known, but we were convinced that the combination with mobile work was so- thing different and new. Our main target became to understand what it was all about. The next step was an expert meeting in October 2004 at Rånäs Castle again in Sweden. A wider group of experts was invited to present their views on mobile virtual work and ideas about book chapters from different perspectives of working life. Some of the expertise could be found through the network of the AMI@Work family created by the New Working En- ronments unit of the European Commission’s Information Society Dir- torate-General. Also close collaboration was developed with the related MOSAIC program.
The Blueprint
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Author : Daniel Rirdan
language : en
Publisher: Daniel Rirdan
Release Date : 2012
The Blueprint written by Daniel Rirdan and has been published by Daniel Rirdan this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Science categories.
From climate change to land degradation to fossil fuel shortages, we are faced with an impending calamity that threatens to bankrupt the planetary ecosystem and with it much of the manmade world. This book offers a plan that truly goes the distance: a highly detailed, planetary-wide blueprint that lays out a new course for our technological and industrial engines. It calls for sweeping adjustments in the way every person thinks and lives.--Inside front cover.
Rethinking Cancer
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Author : Bernhard Strauss
language : en
Publisher: MIT Press
Release Date : 2021-04-27
Rethinking Cancer written by Bernhard Strauss and has been published by MIT Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-27 with Science categories.
Leading scientists argue for a new paradigm for cancer research, proposing a complex systems view of cancer supported by empirical evidence. Current consensus in cancer research explains cancer as a disease caused by specific mutations in certain genes. After dramatic advances in genome sequencing, never before have we known so much about the individual cancer cell--and yet never before has it been so unclear what to do with this knowledge. In this volume, leading researchers argue for a new theory framework for understanding and treating cancer. The contributors propose a complex systems view of cancer, presenting conceptual building blocks for a new research paradigm supported by empirical evidence. The contributors first discuss the new research framework in terms of theoretical foundations and then take up the relevance of a systems approach, reviewing such topics as nonlinearity, recurrence after treatment, the cellular attractor concept, network theory, and non-coding DNA--the "dark matter" of our genome. They address the temporality of cancer progression, drawing on evolutionary theory and clinical experience. Finally, they cover the dominant role of the tissue microenvironment in cancer, analyzing topics including altered metabolic pathways, the disease-defining influence on metastasis, and the interconnectedness of different environmental niches across levels of organization.
A Funny Thing Happened On The Way To Stockholm
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Author : Robert Lefkowitz
language : en
Publisher: Simon and Schuster
Release Date : 2021-02-02
A Funny Thing Happened On The Way To Stockholm written by Robert Lefkowitz and has been published by Simon and Schuster this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-02-02 with Biography & Autobiography categories.
The rollicking memoir from the cardiologist turned legendary scientist and winner of the Nobel Prize that revels in the joy of science and discovery. Like Richard Feynman in the field of physics, Dr. Robert Lefkowitz is also known for being a larger-than-life character: a not-immodest, often self-deprecating, always entertaining raconteur. Indeed, when he received the Nobel Prize, the press corps in Sweden covered him intensively, describing him as “the happiest Laureate.” In addition to his time as a physician, from being a "yellow beret" in the public health corps with Dr. Anthony Fauci to his time as a cardiologist, and his extraordinary transition to biochemistry, which would lead to his Nobel Prize win, Dr. Lefkowitz has ignited passion and curiosity as a fabled mentor and teacher. But it's all in a days work, as Lefkowitz reveals in A Funny Thing Happened on the Way to Stockholm, which is filled to the brim with anecdotes and energy, and gives us a glimpse into the life of one of today's leading scientists.
Practical Aspects Of Design Science
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Author : Markus Helfert
language : en
Publisher: Springer
Release Date : 2012-09-11
Practical Aspects Of Design Science written by Markus Helfert and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-09-11 with Computers categories.
This book constitutes the refereed proceedings of the European Design Science Symposium, EDSS 2011, held in Leixlip, Ireland, in October 2011 held in conjunction with the Intel European Research and Innovation Conference, ERIC 2011. The 15 revised full papers presented were carefully reviewed and selected from various submissions. The papers are organized in topical sections on design science and processes; evaluation and utility; and applying design science.
Antarctic Ecosystems
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Author : K.R. Kerry
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Antarctic Ecosystems written by K.R. Kerry and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
Antarctic Ecosystems comprises 55 papers presented at the Fifth Symposium on Antarctic Biology held under the auspices of the Scientific Committee on Antarctic Research (SCAR) in Hobart, Australia, 29 August - 3 September, 1988. Both short- and long-term changes in ecosystems and community structures caused by natural and human factors were discussed to help understand the ecological processes taking place in a changing environment. The variability of ecological factors must be known for the development of realistic monitoring strategies and sound conservation practices.
Recycling From Waste In Fashion And Textiles
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Author : Pintu Pandit
language : en
Publisher: John Wiley & Sons
Release Date : 2020-07-15
Recycling From Waste In Fashion And Textiles written by Pintu Pandit and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-15 with Science categories.
The alarming level of greenhouse gases in the environment, fast depleting natural resources and the increasing level of industrial effluents, have made every single manufacturing activity come under the scrutiny of sustainability. When all kinds of waste such as clothes, furniture, carpets, televisions, shoes, paper, food wastes etc. end up in the landfill, only a few of them are naturally decomposed and thus a large majority remains as non-biodegradable. It is for this reason, efforts are concentrated to reduce the burden on earth by this waste, and as far as used textile products are concerned, there are now attempts to recycle or up-cycle. This book addresses the role of sustainability by using textile waste in fashion and textiles with respect to manufacturing, materials, as well as the economic and business challenges and opportunities it poses. This wide-ranging book comprises 19 chapters on the various topics including: · Solutions for sustainable fashion and textile industry · Agro and bio waste in the fashion industry · Innovating fashion brands by using textile waste · Waste in handloom textiles · Business paradigm shifting: 21st century fashion from recycling and upcycling · Utilization of natural waste for sustainable textile coloration · Circular economy in fashion and textile from waste · Future pathways of waste utilization for fashion · Sustainable encapsulation of natural dyes from Plant waste for textiles · Agro-waste applications for bio-remediation of textile effluent