The Treatment Of Myeloid Malignancies With Kinase Inhibitors An Issue Of Hematology Oncology Clinics Of North America E Book


The Treatment Of Myeloid Malignancies With Kinase Inhibitors An Issue Of Hematology Oncology Clinics Of North America E Book
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The Treatment Of Myeloid Malignancies With Kinase Inhibitors An Issue Of Hematology Oncology Clinics Of North America E Book


The Treatment Of Myeloid Malignancies With Kinase Inhibitors An Issue Of Hematology Oncology Clinics Of North America E Book
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Author : Ann Mullally
language : en
Publisher: Elsevier Health Sciences
Release Date : 2017-07-14

The Treatment Of Myeloid Malignancies With Kinase Inhibitors An Issue Of Hematology Oncology Clinics Of North America E Book written by Ann Mullally and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-07-14 with Medical categories.


This issue of Hematology/Oncology Clinics will focus on The Treatment of Myeloid Malignancies with Kinase Inhibitors. Articles will focus on: Targeting aberrant signaling in myeloid malignancies: promise versus reality; The development and use of imatinib for the treatment of chronic myelogenous leukemia; Mechanisms of resistance to ABL kinase inhibition in CML and the development of next generation ABL kinase inhibitors; Tyrosine kinase inhibitors in the treatment of systemic mastocytosis and hypereosinophilic syndrome; The development and use of JAK2 inhibitors for the treatment of myeloproliferative neoplasms (MPN); Mechanisms of resistance to JAK2 inhibitors in MPN; Kinase inhibitor screening in myeloid malignancies; and more!



Myeloproliferative Neoplasms An Issue Of Hematology Oncology Clinics Of North America


Myeloproliferative Neoplasms An Issue Of Hematology Oncology Clinics Of North America
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Author : John Mascarenhas
language : en
Publisher: Elsevier Health Sciences
Release Date : 2021-02-27

Myeloproliferative Neoplasms An Issue Of Hematology Oncology Clinics Of North America written by John Mascarenhas and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-02-27 with Medical categories.


This issue of Hematology/Oncology Clinics, guest edited by Drs. Ronald Hoffman, Ross Levine, John Mascarenhas, and Raajit Rampal, is dedicated to Myeloproliferative Neoplasms. This issue is one of six selected each year by the series consulting editors, Drs. George P. Canellos and Edward J. Benz. Topics in this issue include—but are not limited to— Overview of pathophysiology and potential drug targets, The role of the megakaryocyte, Epigenetics, Genetics, Novel technologies for understanding MPN biology, Important pathology considerations, Current Clinical investigations, Quality of life, Application of stem cell therapy, Immunotherapy approaches, Clinical unmet needs in ET/PV, Accelerated and blast phase MPNs, Epidemiology, Thrombotic and hemorrhagic complications, Murine modeling, The microenvironment in MPNs, MDS/MPN overlap syndrome, and Advancing effective clinical trial designs.



Myelodysplastic Syndromes An Issue Of Hematology Oncology Clinics Of North America


Myelodysplastic Syndromes An Issue Of Hematology Oncology Clinics Of North America
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Author : David Steensma
language : en
Publisher: Elsevier Health Sciences
Release Date : 2020-02-26

Myelodysplastic Syndromes An Issue Of Hematology Oncology Clinics Of North America written by David Steensma and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-02-26 with Medical categories.


This issue of Hematology/Oncology Clinics, guest edited by David P. Steensma, will cover key topics in Myelodysplastic Syndromes. This issue is one of six selected each year by our series consulting editors, George P. Canellos and Edward J. Benz. Topics discussed in this issue will include: Novel prognostic models for MDS, Evaluating MDS patients with genetic mutations that might be germline, Implications of splicing mutations in MDS for pathophysiology and therapy, Assessing quality of life in MDS/MPN overlap patients, Creation of a clinic for patients with clonal hematopoiesis, Luspatercept in MDS, Prospects for venetoclax in MDS, Treatment of acquired sideroblastic anemias, Treatment of patients with AML arising from MDS, Targeting TP53 mutations in MDS, among others.



Non Cml Myeloproliferative Diseases An Issue Of Hematology Oncology Clinics Of North America E Book


Non Cml Myeloproliferative Diseases An Issue Of Hematology Oncology Clinics Of North America E Book
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Author : Ross Levine
language : en
Publisher: Elsevier Health Sciences
Release Date : 2012-10-14

Non Cml Myeloproliferative Diseases An Issue Of Hematology Oncology Clinics Of North America E Book written by Ross Levine and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-10-14 with Medical categories.


Topics include: Clinical Predictors of Outcome in MPNs; Molecular pathogenesis of MPNs; Disordered signaling in MPNs; Role of TET2/ASXL1 in MPN Pathogenesis; Pathogenesis and treatment of systemic mastocytosis; Role of additional novel therapies in MPNs; Role of novel mutations in MPN pathogenesis and outcome; Role of JAK inhibitors in MPN treatment; Animal Models of MPNs; and Role of Germline Genetic Factors in MPN Pathogenesis.



Chronic Lymphocytic Leukemia An Issue Of Hematology Oncology Clinics Of North America E Book


Chronic Lymphocytic Leukemia An Issue Of Hematology Oncology Clinics Of North America E Book
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Author : Jennifer R. Brown︎
language : en
Publisher: Elsevier Health Sciences
Release Date : 2021-07-01

Chronic Lymphocytic Leukemia An Issue Of Hematology Oncology Clinics Of North America E Book written by Jennifer R. Brown︎ and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-07-01 with Medical categories.


This issue of Hematology/Oncology Clinics, guest edited by Dr. Jennifer R. Brown?, will focus on Chronic Lymphocytic Leukemia. This issue is one of six selected each year by our series consulting editors, Dr. George P. Canellos and Dr. Edward J. Benz. Topics discussed in this issue will include: Chronic Lymphocytic Leukemia: Do We Know the Cell of Origin Yet?; Significance of BCR Stereotypy; Prognostic and Predictive Implications of Cytogenetics and Genomics; Role of Epigenetics in Chronic Lymphocytic Leukemia; Genomics of Resistance to Targeted Therapies; First Line Therapy for Chronic Lymphocytic Leukemia; The Ongoing Unmet Needs in Chronic Lymphocytic Leukemia Therapy; BTK Inhibitors; Minimal Residual Disease; Should Undetectable MRD Be the Goal of Chronic Lymphocytic Leukemia Therapy?; Management of Chronic Lymphocytic Leukemia after Progression on BTK Inhibitors; Role of PI3K Inhibitors in Chronic Lymphocytic Leukemia; Can We Restore the Immunodeficiency of Chronic Lymphocytic Leukemia?; and Immune Therapy for Chronic Lymphocytic Leukemia



Central Nervous System Malignancies An Issue Of Hematology Oncology Clinics Of North America E Book


Central Nervous System Malignancies An Issue Of Hematology Oncology Clinics Of North America E Book
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Author : David A. Reardon
language : en
Publisher: Elsevier Health Sciences
Release Date : 2021-11-24

Central Nervous System Malignancies An Issue Of Hematology Oncology Clinics Of North America E Book written by David A. Reardon and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-24 with Medical categories.


In this issue of Hematology/Oncology Clinics, guest editor David A. Reardon? brings his considerable expertise to the topic of Central Nervous System Malignancies. Top experts in the field cover key topics such as CNS Metastases, Leptomeningeal Disease, Neurofibromatoses, Imaging Advances for CNS Tumors, and more. Contains 16 relevant, practice-oriented topics including CNS Tumor Classification: An Update on the Integration of Tumor Genetics; Etiology and Epidemiology of CNS Tumors; The Evolving Role of Neurosurgical Intervention for CNS Tumor ; Update on Radiation Therapy for CNS Tumors; and more. Provides in-depth clinical reviews on CNS Malignancies, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.



Waldenstr M Macroglobulinemia An Issue Of Hematology Oncology Clinics Of North America E Book


Waldenstr M Macroglobulinemia An Issue Of Hematology Oncology Clinics Of North America E Book
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Author : Jorge J Castillo
language : en
Publisher: Elsevier Health Sciences
Release Date : 2023-07-03

Waldenstr M Macroglobulinemia An Issue Of Hematology Oncology Clinics Of North America E Book written by Jorge J Castillo and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-07-03 with Medical categories.


In this issue of Hematology/Oncology Clinics, guest editors Drs. Jorge J. Castillo, Prashant Kapoor, and Shayna Sarosiek bring their considerable expertise to the topic of Waldenström Macroglobulinemia. Top experts in the field provide a focused update on the biology, diagnosis and management, and novel therapies for patients with Waldenström macroglobulinemia, a rare blood cell cancer characterized by an excess of abnormal white blood cells in the bone marrow. Contains 14 practice-oriented topics including clinical implications of genomic profile in Waldenström macroglobulinemia; chemoimmunotherapy regimens in the frontline management of Waldenström macroglobulinemia; management of relapsed or refractory Waldenström macroglobulinemia; evaluation and management of aggressive transformation in Waldenström macroglobulinemia; management of Waldenström macroglobulinemia in limited-resource settings; and more. Provides in-depth clinical reviews of Waldenström macroglobulinemia, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.



Melanoma An Issue Of Hematology Oncology Clinics Of North America


Melanoma An Issue Of Hematology Oncology Clinics Of North America
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Author : F. Stephen Hodi
language : en
Publisher: Elsevier Health Sciences
Release Date : 2020-11-25

Melanoma An Issue Of Hematology Oncology Clinics Of North America written by F. Stephen Hodi and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-25 with Medical categories.


This issue of Hematology/Oncology Clinics, Guest Edited by F. Stephen Hodi, is devoted to Melanoma. This issue is one of six selected each year by our series Consulting Editors, George P. Canellos and Edward J. Benz. Topics discussed in this important issue include: State of Melanoma, Biology of Melanoma, Epidemiology of Melanoma, Surgical Management of Melanoma, Melanoma Adjuvant Therapy, Targeted Therapies for Melanoma, Non-cutaneous Melanomas, Immune Checkpoint Therapies for Melanoma, Resistance Mechanisms to Current Therapies, Cellular Therapy and Cytokine Treatments for Melanoma, Combinatorial Approaches to the Treatment of Melanoma, and Melanoma Future Directions.



Trends In Deep Learning Methodologies


Trends In Deep Learning Methodologies
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Author : Vincenzo Piuri
language : en
Publisher: Academic Press
Release Date : 2020-11-12

Trends In Deep Learning Methodologies written by Vincenzo Piuri and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-12 with Computers categories.


Trends in Deep Learning Methodologies: Algorithms, Applications, and Systems covers deep learning approaches such as neural networks, deep belief networks, recurrent neural networks, convolutional neural networks, deep auto-encoder, and deep generative networks, which have emerged as powerful computational models. Chapters elaborate on these models which have shown significant success in dealing with massive data for a large number of applications, given their capacity to extract complex hidden features and learn efficient representation in unsupervised settings. Chapters investigate deep learning-based algorithms in a variety of application, including biomedical and health informatics, computer vision, image processing, and more. In recent years, many powerful algorithms have been developed for matching patterns in data and making predictions about future events. The major advantage of deep learning is to process big data analytics for better analysis and self-adaptive algorithms to handle more data. Deep learning methods can deal with multiple levels of representation in which the system learns to abstract higher level representations of raw data. Earlier, it was a common requirement to have a domain expert to develop a specific model for each specific application, however, recent advancements in representation learning algorithms allow researchers across various subject domains to automatically learn the patterns and representation of the given data for the development of specific models. Provides insights into the theory, algorithms, implementation and the application of deep learning techniques Covers a wide range of applications of deep learning across smart healthcare and smart engineering Investigates the development of new models and how they can be exploited to find appropriate solutions



Non Hodgkin S Lymphoma An Issue Of Hematology Oncology Clinics Of North America


Non Hodgkin S Lymphoma An Issue Of Hematology Oncology Clinics Of North America
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Author : Caron A Jacobson
language : en
Publisher: Elsevier Health Sciences
Release Date : 2019-06-22

Non Hodgkin S Lymphoma An Issue Of Hematology Oncology Clinics Of North America written by Caron A Jacobson and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-22 with Medical categories.


This issue of Hematology/Oncology Clinics, guest edited by Dr. Caron A. Jacobson, with consulting editors George P. Canellos and H. Franklin Bunn, will focus on Non-Hodgkin’s Lymphoma. Topics include, but are not limited to: Ontogeny, Genetics, Molecular Biology and Classification of B and T cell Non-Hodgkin’s Lymphoma; Diffuse large B cell lymphoma and high grade B cell lymphoma; Burkitt lymphoma and other highly aggressive B cell lymphomas; CNS lymphoma; Mantle cell lymphoma; Follicular lymphoma; Marginal zone lymphoma and lymphoplasmacytic lymphoma; Non-cutaneous T cell lymphoma; Cutaneous T cell lymphoma; Transplant and other adoptive immune cell therapies for non-Hodgkin lymphoma; Non-cellular immune therapies for non-Hodgkin’s lymphoma; and Targeting biology in non-Hodgkin’s lymphoma.