The Variant Virus
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The Variant Virus
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Author : G. A. Mohr, PhD
language : en
Publisher: Xlibris Corporation
Release Date : 2012-06-28
The Variant Virus written by G. A. Mohr, PhD and has been published by Xlibris Corporation this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-06-28 with Fiction categories.
The book is the fi rst on the adventures of Briti sh secret agent Simon Sinclair who works mainly for Counter Terrorism Intelligence (Operati ons), or CT3, in conjuncti on with MI5, MI6 and the CIA. The book is a ‘future threat’ scenario, the threat in questi on being technologically feasible on grand scale as far back as the mid 1980s when an accident at Vektor, one of Russia’s then 50 Biological Warfare faciliti es, infected Usti nov with Marburg fi lovirus which evolved in the 15 days it took to liquefy all his organs into ‘Marburg Variant U’ which was then put atop SS16 rockets. In this gripping tale a recombinant or ‘dual’ virus is smuggled into England by CABAL, the Confederati on Against Briti sh-American Logisti cs, an internati onal group opposed to Briti sh and American power and infl uence that CABAL sees as hegemony. CABAL gives seven days noti ce of att acks on London. Aft er a CABAL att empt on his life Sinclair follows his att acker to Colombia where he learns the identi ti es of four CABAL ‘money men’ and captures one of them, the money trail left by these fi nanciers leading to the identi ty of CABAL’s operati onal leaders. Sinclair succeeds in thwarti ng four CABAL bomb att acks and stops helicopters heading to London with the virus, but not without fallout which threatens an epidemic. First symptoms of smallpox appear, and then those of a new and highly virulent strain of Marburg fi lovirus which causes haemorrhagic fever and liquefacti on of the organs. Sinclair fi nds a cure for the recombinant virus in Russia and spread throughout London, if not England or internati onally, is avoided. Many CABAL members have been captured or killed and for good measure Sinclair captures two of the three remaining top organizers sti ll at large. Refl ecti ng on a very hecti c three weeks during which England faced the greatest threat in its history, Sinclair realizes that there is a mole in CT3, leaving him a diffi cult future assignment but, at the same ti me, giving him an idea that might, given ti me, help shut down major terrorist organizati ons such as CABAL and Al Qa’ida for good.
Variants The Shape Shifting Challenge Of Covid 19
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Author : William A. Haseltine
language : en
Publisher: Access Health International
Release Date : 2021-02-15
Variants The Shape Shifting Challenge Of Covid 19 written by William A. Haseltine and has been published by Access Health International this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-02-15 with categories.
People live in a sea of viruses. All creatures are host to these small organisms, which are made up of small bits of genetic information. Viruses are possessed by a drive to survive, but in order to reproduce they must invade a living cell. Dr. William A. Haseltine, PhD, has spent a lifetime studying viruses and their ability to adapt and flourish within an ever-changing environment. In Variants! The Shape-Shifting Challenge of COVID-19, Dr. Haseltine turns his focus to SARS-CoV-2, the virus that causes COVID-19. The variant forms of this coronavirus risk an even greater disruption to our lives, our economy, and the health and wellbeing of hundreds of billions worldwide. Variants! is a collection of Dr. Haseltine's writings and research on COVID-19 and SARS-CoV-2 mutations and variants. The book is a Living eBook, updated regularly with new information as it unfolds. When a reader purchases a copy of the book, either in print or online, they will receive a special passcode that will give them online access to every subsequent edition of the book, as it is released.
Evolution Of Sars Cov 2 Impact Of Variants On Hosts Covid 19 Vaccines And Countermeasures
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Author : Seshadri Vasan
language : en
Publisher: Frontiers Media SA
Release Date : 2024-02-20
Evolution Of Sars Cov 2 Impact Of Variants On Hosts Covid 19 Vaccines And Countermeasures written by Seshadri Vasan and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-02-20 with Science categories.
The ‘novel coronavirus disease’ (COVID-19) has caused significant global morbidity, mortality and economic damage on a scale similar to the influenza pandemic of 1918. The causative ‘severe acute respiratory syndrome virus 2’ (SARS-CoV-2) is a RNA virus which is evolving rapidly, accumulating mutations, and existing as a cloud of variants with quasispecies diversity. We have tens of thousands of variants, of which currently two are ‘variants of interest’ (Lambda, Mu) and another four ‘variants of concern’ (Alpha, Beta, Gamma, Delta, Omicron) to the World Health Organization (WHO). Variants of interest often emerge as variants under investigation in one or more countries, as seen with the Omicron (initially denoted as Nu in South Africa). They become variants of concern when there is evidence of increased transmissibility, greater case severity, loss of neutralization by antibodies, and reduced effectiveness of countermeasures. Some SARS-CoV-2 variants can infect new hosts (for instance, the Alpha, Beta and Gamma variants of concern can infect wild type mice which is a species that cannot be vaccinated or controlled easily), and/or reduce the effectiveness of vaccines and therapies (especially Beta and Delta); diagnostic tests have also been reported to be affected. Currently, we do not yet have any ‘variant of high consequence’ with confirmed attributes such as widespread diagnostic test failures, significant reduction in the effectiveness of vaccines and/or therapies, with greater disease severity and deaths. It remains to be seen if Omicron would be the first to be declared by the WHO as a variant of high consequence; more variants of concern are also likely to be declared by the WHO over the next couple of years. Therefore, our ability to control and conquer this pandemic over the long run is dependent on predicting and keeping up with the evolution of this virus, its new hosts, as well as understanding and mitigating its impact on diagnostics, vaccines and therapies.
Sars Cov 2 Spike Protein Convergent Evolution
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Author : Daniele Focosi
language : en
Publisher: Springer Nature
Release Date : 2021-10-11
Sars Cov 2 Spike Protein Convergent Evolution written by Daniele Focosi and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-11 with Medical categories.
This book reviews the current knowledge of the globally circulating SARS-CoV-2 variants, highlights their distinct genetic characteristics and associated conformational changes in the viral spike protein, and profoundly discusses the mechanisms of convergent evolution that led to the rise of these mutated strains at different geographic regions during the Covid-19 pandemic. Furthermore, the book explores how these variants do and may impact the efficacy of established neutralizing antibody-based (nAb) vaccines and therapeutics by analysing latest in vivo and in vitro clinical data. Finally, the author discusses ways on how nAb Covid-19 treatment derived immune escape of SARS-CoV-2 could be minimized in the future.
Covid 19 New Variants And Host Demography
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Author : Ginpreet Kaur
language : en
Publisher: Frontiers Media SA
Release Date : 2022-05-26
Covid 19 New Variants And Host Demography written by Ginpreet Kaur and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-26 with Science categories.
Variant C 19
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Author : Robert Dresner
language : en
Publisher:
Release Date : 2021-04
Variant C 19 written by Robert Dresner and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04 with categories.
Variant is a story about becoming different, as a result of having covid-19, and not knowing why.It is a creative journal recounting one year in the life of the dreaded virus in my body and in my mind. The story is intense and far reaching-if only because this virus has affected every aspect of our lives, and because our response to this medical emergency has been so terribly mishandled. As a result, there are many symptoms of Covid-19 that are still misunderstood and grossly under-reported: Why do so many of us, who had the virus, feel different?Why don't we have a true and common sense of healing?Is it physical, emotional, psychological-or something else?
Sars Cov 2 Variants And Global Population Vulnerability
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Author : Vivek P. Chavda
language : en
Publisher: CRC Press
Release Date : 2024-07-05
Sars Cov 2 Variants And Global Population Vulnerability written by Vivek P. Chavda and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-07-05 with Medical categories.
SARS-CoV-2, the coronavirus responsible for COVID-19, wreaked havoc on the world; it could both spread easily and mutate rapidly, leading to the decrease in the effectiveness of newly developed vaccines over time. The detection of these mutated variants and the development of more efficient vaccines requires significant effort and increased knowledge in this field. This new book, SARS-CoV-2 Variants and Global Population Vulnerability: Diagnostic Strategies, Vaccine Development, and Therapeutic Management, provides detailed and systemic information regarding the biology and immunophysiology of SARS-CoV-2 and highlights the global vulnerability of the world population to SARS-CoV-2 infection and COVID-19. The book covers different aspects pertaining to the SARS-CoV-2 variants and their relation to global vulnerability. Chapters discuss the diagnostics, vaccine development, and therapeutic management starting from the zoonotic origin, organization, and transmission of SARS-CoV-2, lifestyle and immunophysiology of the virus, detection and diagnosis techniques, and analytical techniques. The book also observes the global impact of Delta and Omicron SARS-CoV-2 variants. It looks at the drug repurposing and new drug discovery routines for the emerging variants. It presents strategies for fast-track vaccine development, the roles of nasal vaccines and nucleic acid vaccines for COVID-19 management, monoclonal antibody therapy for the diseases management, along with the use of dietary supplements and nutraceuticals, herbal drugs, and other alternative remedies for COVID-19 management. The book also considers the social and environmental impacts of SARS-CoV-2 variants and the current challenges, outlining aspects that can help in developing more efficacious means for controlling SARS-CoV-2 in the future. Key highlights: Discusses SARS-CoV-2 variants, diagnosis strategies, vaccine development, and the therapeutic management of the disease Provides comprehensive coverage of SARS-CoV-2 virus and variants With its unique and thorough take on the subject, this book is an important resource of know-how for investigators working in this area. Professionals from the pharmaceutical industry as well as students, research scholars, doctors, and other healthcare professionals will find this book of particular value.
Emerging Sars Cov 2 Variants Genomic Variations Transmission Pathogenesis Clinical Impact And Interventions Volume Ii
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Author : Pragya Dhruv Yadav
language : en
Publisher: Frontiers Media SA
Release Date : 2023-07-20
Emerging Sars Cov 2 Variants Genomic Variations Transmission Pathogenesis Clinical Impact And Interventions Volume Ii written by Pragya Dhruv Yadav and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-07-20 with Medical categories.
New Covid 19 Variants Diagnosis And Management In The Post Pandemic Era
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Author : Ozgur Karcioglu
language : en
Publisher: BoD – Books on Demand
Release Date : 2024-04-18
New Covid 19 Variants Diagnosis And Management In The Post Pandemic Era written by Ozgur Karcioglu and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-04-18 with Medical categories.
New COVID-19 Variants - Diagnosis and Management in the Post-Pandemic Era provides a comprehensive overview of COVID-19, focusing on new variants and their diagnosis, treatment, and prevention. Due to the emergence of new viral variants, cases of COVID-19 are expected to increase. Thus, it is vital to take the necessary precautions to protect society and its most vulnerable members like the elderly and immunocompromised. This book discusses protective measures such as social distancing, mask mandates, vaccinations, and more.
A Closer Look At The Covid 19 Variants
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Author : Richard D. Hylton
language : en
Publisher: Nova Snova
Release Date : 2022-09-30
A Closer Look At The Covid 19 Variants written by Richard D. Hylton and has been published by Nova Snova this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-09-30 with categories.
As viruses spread, small errors - called mutations - arise in the genetic material during replication. Many of these mutations are repaired or die off as the virus continues to move through a population. Mutations that enhance the virus's ability to replicate, transmit, or survive in a host allow the virus to spread more quickly through a population, or become more resistant to immune system defenses, thereby increasing the mutations' prevalence and creating a new strain of the virus. The purpose of this book is to discuss how variants develop, how researchers identify and sequence variants, and how this information can be utilized by public health officials, government agencies, and medical practitioners to make decisions. The book examines the ways the government can better coordinate its approach to best serve the American people through this pandemic and beyond.