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The Vascular Endothelium I


The Vascular Endothelium I
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The Vascular Endothelium I


The Vascular Endothelium I
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Author : Salvador Moncada
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-12-22

The Vascular Endothelium I written by Salvador Moncada and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-12-22 with Medical categories.


This wide ranging work provides a complete representation of the present state of knowledge of the vascular endothelium. The volume comprises 20 chapters by experts who have made significant contributions to research in the vascular endothelium. The text discusses the structure, development and function of the normal vascular endothelium, considers conditions that lead to the disruption of vascular physiology and provides a comprehensive description of pathologies and their treatment.



The Vascular Endothelium Ii


The Vascular Endothelium Ii
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Author : Salvador Moncada
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-10-14

The Vascular Endothelium Ii written by Salvador Moncada and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-10-14 with Medical categories.


This wide ranging work provides a complete representation of the present state of knowledge of the vascular endothelium. The volume comprises 20 chapters by experts who have made significant contributions to research in the vascular endothelium. The text discusses the structure, development and function of the normal vascular endothelium, considers conditions that lead to the disruption of vascular physiology and provides a comprehensive description of pathologies and their treatment.



Vascular Endothelium


Vascular Endothelium
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Author : John D. Catravas
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Vascular Endothelium written by John D. Catravas and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


This monograph contains the proceedings from the Advanced Study Institute on "Vascular Endothelium: Physiological Basis of Clinical Problems" which took place in Corfu, Greece in June 1990. The meeting consisted of twenty-eight lectures, most of them adapted as full length papers in this volume, as well as numerous short oral and poster communications which are abstracted and also included in alphabetical order (pages 239-302). There were ninety-six participants from ten NATO and four other European countries. The meeting was the second in as many years dealing with a specific subject in Endothelial Cell biology. Following the 1988 discussion on "Receptors and Transduction Mechanisms", the present ASI recognized and tried to deal with the increasing overlap in interest between basic scientists studying endothelial cell functions and clinicians facing problems of known or suspected endothelial pathological involvement. As with any similar effort, we opted to be selective, rather than fail by trying to be inclusive, in the subjects covered. We chose to discuss diseases, such as atherosclerosis, sepsis, ARDS and stroke, based on their relevance to endothelial cell function and urgent need for new insights into their pathogenesis and treatment. Similarly, we examined endothelial cell functions by considering their relevance to disease and their potential for elucidating important pathologies. Obviously, some areas were covered superficially or not at all; this should not distract from their importance, but rather reflect on the constraints of time and -not at all negligibly -the bias of the organizing committee.



Vascular Endothelium In Human Physiology And Pathophysiology


Vascular Endothelium In Human Physiology And Pathophysiology
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Author : Patrick J Vallance
language : en
Publisher: CRC Press
Release Date : 2003-09-02

Vascular Endothelium In Human Physiology And Pathophysiology written by Patrick J Vallance and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-09-02 with Medical categories.


Endothelial dysfunction is now regarded as an early marker of vascular disease and therefore an important target for therapeutic intervention and discovery of novel treatments. Ideal for both basic and clinical scientists, whether in industry or academia, and physicians, Vascular Endothelium in Human Physiology and Pathophysiology provides an up-to



The Endothelium


The Endothelium
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Author : Michel Félétou
language : en
Publisher: Morgan & Claypool Publishers
Release Date : 2011

The Endothelium written by Michel Félétou and has been published by Morgan & Claypool Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Science categories.


The endothelium, a monolayer of endothelial cells, constitutes the inner cellular lining of the blood vessels (arteries, veins and capillaries) and the lymphatic system, and therefore is in direct contact with the blood/lymph and the circulating cells. The endothelium is a major player in the control of blood fluidity, platelet aggregation and vascular tone, a major actor in the regulation of immunology, inflammation and angiogenesis, and an important metabolizing and an endocrine organ. Endothelial cells controls vascular tone, and thereby blood flow, by synthesizing and releasing relaxing and contracting factors such as nitric oxide, metabolites of arachidonic acid via the cyclooxygenases, lipoxygenases and cytochrome P450 pathways, various peptides (endothelin, urotensin, CNP, adrenomedullin, etc.), adenosine, purines, reactive oxygen species and so on. Additionally, endothelial ectoenzymes are required steps in the generation of vasoactive hormones such as angiotensin II. An endothelial dysfunction linked to an imbalance in the synthesis and/or the release of these various endothelial factors may explain the initiation of cardiovascular pathologies (from hypertension to atherosclerosis) or their development and perpetuation. Table of Contents: Introduction / Multiple Functions of the Endothelial Cells / Calcium Signaling in Vascular Cells and Cell-to-Cell Communications / Endothelium-Dependent Regulation of Vascular Tone / Conclusion / References



Vascular Endothelium


Vascular Endothelium
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Author : John D. Catravas
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Vascular Endothelium written by John D. Catravas and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


This book is a compilation of the lectures and oral and poster communications presented at the Advanced Study. Institute on "Vascular Endothelium: Physiological Basis of Clinical Problems II," which took place between June 20 and 30, 1992 in Rhodes, Greece. This third in a series of ASIs on vascular endothelium continued on the theme of the first (1988) ASI on "Receptors and Transduction Mechanisms" and particularly expanded that of the 1990 conference on ''Physiological Basis of Clinical Problems. " We continued the successful practice of bringing together clinicians and scientists: this was reflected equally well in the composition of the organizing committee as in the background of the particiJ?ants. Endothelial cell functions and dysfunctions present as many challenges to the mvestigator as they do to the curious clinical practitioner. As these problems are necessarily different, this unique ten-day co-habitation of these individuals continued to offer fresh outlooks to each, stimulated potential collaborative efforts and, most importantly, advanced --ever so slightly--our knowledge of vascular biology. This year's conference was further enriched by the presence of several of our colleagues from Eastern Europe whom we are delighted to welcome as officially sponsored participants to this and future NATO-supported meetings. It is never superfluous to remind readers and participants that those signing at the bottom of this page, while responsible for many of the ASI's and the book's deficiencies, are but three of the many contributors to the successes.



The Vascular Endothelium


The Vascular Endothelium
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Author : Domenico Ribatti
language : en
Publisher: Academic Press
Release Date : 2022-05-29

The Vascular Endothelium written by Domenico Ribatti and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-29 with Science categories.


The Vascular Endothelium: A Holistic Approach for Oncology provides novel and integrated knowledge on the endothelial cells as a crucial component involved in the growth of different organs in both physiological and pathological conditions. By covering diverse aspects of anatomy, embryology, molecular biology and pathology, it details the important role of the endothelium for the pathogenesis of cancer and how this knowledge can improve the outcome of cancer research.The content is split in six parts: appearance and evolution of the endothelial cell, which discusses for instance comparative anatomy of the endothelium in relation to the vascular system; endothelial cell in embryology and organogenesis, covering the interaction between endothelial and hematopoietic cells; the lymphatic system, which brings information on lymphatic endothelial cell markers and molecular regulation of lymphangiogenesis; the anatomy of the endothelium in adults, showing the differences in the mature endothelial cells through the body; the physiology of the endothelial cells, with organ specific physiological activity of the endothelium; and the endothelial cells in cancer, discussing the use of endothelium as target for treatment and current therapeutic approaches.This book is a valuable resource for cancer researchers, oncologists and other members of biomedical field who are interested to learn more about the complexity of vascular endothelium and its impact on cancer and other related diseases. Provides a holistic approach to the knowledge of endothelial cells in different organs, from early years of development to adulthood Discusses relevant aspects of endothelial cells related to the pathogenesis of cancer to be applied to novel therapeutics Presents an interdisciplinary view of the vascular endothelium, covering anatomy, embryology, molecular biology, pathology and clinical implications



Vascular Endothelium In Health And Disease


Vascular Endothelium In Health And Disease
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Author : Shu Chien
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-09

Vascular Endothelium In Health And Disease written by Shu Chien and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-09 with Medical categories.


In recent years there has been rapid progress in research on vascular endothelium. This has led to significant advances in our understanding of the structure and function of vascular endothelium in health and disease, including such aspects as the permeability of endothelium in relation to its ultrastructural correlates, theoretical basis, regulatory factors, and role in atherogenesis; the interaction between endothelium and blood cells; the endothelial release and processing of a number of important physiological agents, such as eicosanoids, hemostatic factors, and histamine; the cell biology of endothelium with respect to the cytoskeletal apparatus, cell activation, and cell locomotion; and the role of endothelium in microcirculatory regulation in normal and pathophysiological circumstances. A Symposium on "Vascular Endothelium in Health and Disease" was held on August 5-6, 1987, at the Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan, Republic of China, following the 4th World Congress for Microcirculation in Japan. Experts working on various aspects of vascular endothelium came from allover the world to participate in this two-day Symposium and gave excellent presentations. This volume, embodying the proceedings of that Symposium, is a collection of the papers given by the speakers with, in many cases, further updating and new information added subsequent to the Symposium. The Institute of Biomedical Sciences (IBMS), the site of this Symposium, is a newlJl established research institution, which has vascular endothelium as one of its areas of research emphasis.



Vascular Endothelium


Vascular Endothelium
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Author : J. Catravas
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29

Vascular Endothelium written by J. Catravas and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Science categories.


Beyond their obvious role of a barrier between blood and tissue, vascular endothelial cells are now firmly established as active and essential participants in a host of crucial physiological and pathophysiological functions. Probably the two most important factors responsible for promoting the current knowledge of endothelial functions are 1) observations in the late sixties-early seventies that many non-ventilatory properties of the lung could be attributed to the pulmonary endothelium and 2) the establishment, in the early and mid-seventies of procedures for routine culture of vascular endothelial cells. Many of these endothelial functions require the presence of receptors on the surface of the plasma membrane. There is now evidence for the existence among others of muscarinic, a-and /3-adrenergic, purine, insulin, histamine, bradykinin, lipoprotein, thrombin, paf, fibronectin, vitronectin, interleukin and albumin receptors. For some of these ligands, there is evidence only for the existence of endothelial binding sites. Traditionally, agonist binding must elicit a response for the binding site to be considered a receptor and, in some cases, the nature of the response resulting from the interaction of a substance with the endothelium remains unclear. It is beyond the scope of this introduction to even enumerate the various endothelial homeostatic processes. This monograph contains the proceedings of the Advanced Studies Institute on "Vascular Endothelium: Receptors and Transduction Mechanisms" held in Porto Carras, Greece from June 18-29, 1988.



Vascular Endothelium


Vascular Endothelium
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Author : John D. Catravas
language : en
Publisher: IOS Press
Release Date : 1999

Vascular Endothelium written by John D. Catravas and has been published by IOS Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with Science categories.


With its innovative topical approach, bestselling COMPARATIVE CRIMINAL JUSTICE SYSTEMS, 5e offers a comprehensive analysis as it compares the various criminal justice systems throughout the world using six model countries: China, England, France, Germany, Japan, and Saudi Arabia. The text illustrates the different types of law and justice systems while exploring the historical, political, economic, social, and cultural influences on each system. This unique approach examines important aspects of each type of justice system--common law, civil law, socialist law, and sacred (Islamic) law--to give students a thorough understanding of the similarities and differences of each system without overloading them with too much information. Completely up to date, the Fifth Edition includes the latest trends and issues in international juvenile justice, policing, and terrorism, including expanded coverage of such high- profile topics as human trafficking, Internet pornography, identity theft, transnational policing, and more.