Therapeutic Control Of Inflammatory Diseases
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Therapeutic Control Of Inflammatory Diseases
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Author : Ivan Otterness
language : en
Publisher: Lippincott Williams & Wilkins
Release Date : 1986
Therapeutic Control Of Inflammatory Diseases written by Ivan Otterness and has been published by Lippincott Williams & Wilkins this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986 with Medical categories.
Therapeutic Control Of Inflammatory Diseases
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Author : Ivan Otterness
language : en
Publisher: Lippincott Williams & Wilkins
Release Date : 1984
Therapeutic Control Of Inflammatory Diseases written by Ivan Otterness and has been published by Lippincott Williams & Wilkins this book supported file pdf, txt, epub, kindle and other format this book has been release on 1984 with Medical categories.
Therapeutic Control Of Inflammatory Diseases
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Author : Ivan Otterness
language : en
Publisher:
Release Date : 1984-01-01
Therapeutic Control Of Inflammatory Diseases written by Ivan Otterness and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1984-01-01 with categories.
Advances In Inflammation Research Therapeutic Control Of Inflammatory Diseases
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Author :
language : en
Publisher:
Release Date : 1979
Advances In Inflammation Research Therapeutic Control Of Inflammatory Diseases written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1979 with Inflammation categories.
Recent Developments In Anti Inflammatory Therapy
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Author : Parteek Prasher
language : en
Publisher: Academic Press
Release Date : 2023-02-17
Recent Developments In Anti Inflammatory Therapy written by Parteek Prasher and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-02-17 with Medical categories.
Advances in Anti-inflammatory Therapy explores the cutting-edge in anti-inflammation therapy in clear and concise language, with insights from academia and industry. Sections cover key regulatory pathways that mediate acute and chronic inflammation and disease onset. Further chapters are devoted to advanced anti-inflammatory pharmaceuticals, including chemical moieties, pharmacophores, APIs, natural products, herbal therapies, molecular nanomedicine and advanced drug delivery vectors. Systematically planned chapters and illustrations enable potential readers to gain essential insights on the most recent advancements in the field. Arranged with systematic chapters covering a broad range of inflammatory diseases, discussions on past, current and future therapeutics and advanced anti-inflammatory pharmaceuticals, this book will be useful to a wide range of researchers, especially medicinal chemists, drug design experts, and biological and translational researchers working in the field of inflammation. Identifies recent developments and current trends in anti-inflammation therapy Discusses advanced chemotherapeutics, SAR analysis of novel pharmacophores and natural products Outlines the pathophysiology of inflammatory pathways in the pathogenesis of disease onset, including strategies to counter these intricacies Contains a blend of editors from both academia and industry
Towards Therapeutic Disease Control In Inflammatory Bowel Diseases
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Author : Anne Christine Wilhelmina Vos
language : en
Publisher:
Release Date : 2011
Towards Therapeutic Disease Control In Inflammatory Bowel Diseases written by Anne Christine Wilhelmina Vos and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with categories.
Regulation Of Inflammation Its Resolution And Therapeutic Targeting
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Author : Mariagrazia Uguccioni
language : en
Publisher: Frontiers Media SA
Release Date : 2018-01-11
Regulation Of Inflammation Its Resolution And Therapeutic Targeting written by Mariagrazia Uguccioni and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-11 with Electronic book categories.
Inflammation is a fundamental protective mechanism and at the same time the driving force of a variety of major diseases in humans. Indeed, acute self-resolving inflammation usually plays a positive role for the host, as exemplified by infectious diseases where its positive role is well established and testified by its perception as innate immunity. On the other hand, non-resolving inflammation and consequent chronicization is a key determinant of immunopathology and clinical manifestations of most major diseases in humans. As a consequence, it is increasing appreciated that the problem with inflammation is not how often it starts, but how often it fails to resolve. Appropriate resolution of inflammatory responses, which also drives activation of tissue damage repair mechanisms and return of local tissues to homeostasis, is a necessary process for ongoing health. Interestingly, cells sustaining these processes are also key to the proinflammatory responses, and the underlying “pro-resolving” molecular pathways are triggered as part of the pro-inflammatory response. This clearly indicates resolution of inflammation as an active process requiring functional repolarization of inflammatory cells that calls our attention on the underlying molecular mechanisms. The increasing number of anti-inflammatory drugs best-sellers in the pharma market is a clear indication of the relevance of having inflammation under check; nonetheless, there is still a great need for better acting pharmacological tools for the control of inflammation. Indeed, the remarkable success of biological drugs targeting proinflammatory cytokines has indicates that tools able to block proinflammatory mediators have promising applications, but at the same time has made clear that there are intrinsic limitations to this approach which frequently vanish undermine the activity of single targeting drugs, including the well-known redundancy of inflammatory mediators. Under self-limiting conditions inflammation spontaneously resolves in an active process. Some cellular and molecular mechanisms involved in inflammation resolution have been uncovered in the recent past, and include generation of specific cytokines, apoptosis of inflammatory leukocytes, lipid mediators, macrophage repolarization and others are likely to be revealed in the next future, since loss-of-function mutations of an increasing number of genes results in the development of spontaneous inflammation in experimental animals. We argue that “pushing for“ inflammation resolution by exploiting active naturally-occurring pro-resolving processes may have significant advantages over the attempt to simply “push back” inflammation by passive blockade of proinflammatory mediators. At present the research in the field of inflammation aims at identifying and validates new molecules involved in the resolution of inflammation as a basis for the development of innovative therapeutic strategies in chronic inflammatory and autoimmune diseases. This involves the discovery of new natural or synthetic “pro-resolving” molecules from plant and animals and the investigation of endogenous inflammation “pro-resolving” mechanisms, including atypical chemokine receptors, decoy receptors, and microRNA. An extensive effort is focused on the regulation by “pro-resolving” agents on two molecular systems of key relevance in inflammation: the chemokine system, which regulates recruitment, permanence and egress of leukocyte in tissues; and the Toll Like Receptor (TLR)/IL-1R system, which is central for the activation of infiltrating leukocytes.
Role Of The Il 23 Il 17 Pathway In Chronic Immune Mediated Inflammatory Diseases Mechanisms And Targeted Therapies
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Author : Elisabetta Bianchi
language : en
Publisher: Frontiers Media SA
Release Date : 2021-11-10
Role Of The Il 23 Il 17 Pathway In Chronic Immune Mediated Inflammatory Diseases Mechanisms And Targeted Therapies written by Elisabetta Bianchi and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-10 with Medical categories.
Nanomedicine For Inflammatory Diseases
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Author : Lara Scheherazade Milane
language : en
Publisher: CRC Press
Release Date : 2017-09-19
Nanomedicine For Inflammatory Diseases written by Lara Scheherazade Milane and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-19 with Medical categories.
Nanomedicine for Inflammatory Diseases is a cutting-edge resource for clinicians and scientists alike, working at the intersection of development and clinical therapeutics. This text is ideal for graduate level courses in nanomedicine, translational medicine, or inflammatory disease. This book is a progressive hallmark in translational medicine as it unites clinicians treating inflammatory disease with scientists developing experimental nanomedicine therapeutics. The commonality is made through a translational nanomedicine expert – bridging the gap between the laboratory benchtop and the clinical bedside.
Therapeutic Strategies For Modulating The Inflammatory Diseases
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Author : B.M. Weichman
language : en
Publisher: Springer Science & Business Media
Release Date : 1997-11-18
Therapeutic Strategies For Modulating The Inflammatory Diseases written by B.M. Weichman and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-11-18 with Medical categories.
The Eighth International Conference of the Inflammation Research Association was held on October 27 to 31, 1996 at Hershey Lodge and Convention Center in Hershey, Pennsylvania. As have others in this series, the conference focused on understanding the molecular mechanisms involved in acute and chronic inflammatory reactions as well as on therapeutic approaches to treating inflammatory diseases. One outstanding symposium focused on new drugs and was de signed as a forum for the dissemination of early clinical results on new anti-inflammatory agents. Other symposia spotlighted exciting advances being made in defining intracellular signaling path ways and the potential for future therapeutics that target cytokines and costimulatory pathways. This conference was characterized by a high level of participation by attendees, who represent both the academic and industrial sectors. It was gratifying to note that a large proportion of the attending scientists presented their latest findings during workshops, poster discussions, and pos ter se.ssions. This volume covers many of the highlights of the Eighth International Conference and should become a valuable resource for scientists involved in inflammation research and drug discovery.