Recent Developments In Anti Inflammatory Therapy
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Recent Developments In Anti Inflammatory Therapy
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Author : Parteek Prasher
language : en
Publisher: Academic Press
Release Date : 2023-02-17
Recent Developments In Anti Inflammatory Therapy written by Parteek Prasher and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-02-17 with Medical categories.
Advances in Anti-inflammatory Therapy explores the cutting-edge in anti-inflammation therapy in clear and concise language, with insights from academia and industry. Sections cover key regulatory pathways that mediate acute and chronic inflammation and disease onset. Further chapters are devoted to advanced anti-inflammatory pharmaceuticals, including chemical moieties, pharmacophores, APIs, natural products, herbal therapies, molecular nanomedicine and advanced drug delivery vectors. Systematically planned chapters and illustrations enable potential readers to gain essential insights on the most recent advancements in the field. Arranged with systematic chapters covering a broad range of inflammatory diseases, discussions on past, current and future therapeutics and advanced anti-inflammatory pharmaceuticals, this book will be useful to a wide range of researchers, especially medicinal chemists, drug design experts, and biological and translational researchers working in the field of inflammation. Identifies recent developments and current trends in anti-inflammation therapy Discusses advanced chemotherapeutics, SAR analysis of novel pharmacophores and natural products Outlines the pathophysiology of inflammatory pathways in the pathogenesis of disease onset, including strategies to counter these intricacies Contains a blend of editors from both academia and industry
Novel Molecular Approaches To Anti Inflammatory Therapy
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Author : Waldemar Pruzanski
language : en
Publisher: Birkhäuser
Release Date : 2014-01-14
Novel Molecular Approaches To Anti Inflammatory Therapy written by Waldemar Pruzanski and has been published by Birkhäuser this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-01-14 with Medical categories.
In July 1994, the Canadian Inflammation Society in Toronto hosted a symposium entitled "Novel molecular approaches to anti-inflammatory therapy" as a satellite of the xnth International Congress of Pharmacology. For several reasons the above topic was singled out and separated from the general Congress. Major advances have recently been made in the understanding of inflammatory mechanisms. These advances serve as the basis for a new generation of therapeutic agents which may potentially alter our approach to inflammatory processes and infectious diseases. The Satellite Symposium focused on recent advances in diversified fields including arachidonate metabolites, actions of cytokines, chemokines, cellular adhesion molecules and novel molecular approaches in the therapy of inflammation. Scholarly addresses were presented by eminent experts in their respective fields. In this book are included 17 papers which describe in detail novel approaches to the study of inflammation. We hope that this book will serve not only as a summary of present knowledge, but will stimulate both scientists and clinicians to continue their efforts to battle inflammatory diseases. W. Pruzanski, Chair, Publications Committee P. Vadas, Chair, Organizing Committee 1 AAS46 Novel Molecular Approaches to Anti-Inflammatory Theory © 1995 Birkhauser Verlag Basel EOSINOPHIL CHEMOATIRACTANIS GENERATED IN VIYO T. I. Williams, D. A. Griffiths-Iohnson, P. I. lose and P. D. Collins. Department of Applied Pharmacology, National Heart and Lung Institute, Dovehouse Street, London SW3 6LY, United Kingdom.
New Developments In Antirheumatic Therapy
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Author : K. D. Rainsford
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
New Developments In Antirheumatic Therapy written by K. D. Rainsford and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
At present we may be at the cross-roads in the therapeutic approaches we have for the treatment of the 100 or more rheumatic conditions. This is be cause we now recognise that although some advances have been made with the development of a large range of non-steroidal and steroidal drugs during the past two decades or so, we now recognise that many, if not all, of these have rather limited effects on many of the disease processes which underlie the manifestations of the various rheumatic states. Advances in molecular bi- 010gy in the past 5-10 years have enabled these tools to be applied extensive ly for developing further our understanding of the rheumatic disease processes. In some cases these molecular tools (e. g. ,),-interferon, interleukin- 2, T-cell antibodies) have been directly employed as therapies themselves. While the outcome from trials with such agents in rheumatoid arthritis in particular has not been as would have been hoped, these results as with cy closporin A and low-dose methotrexate in the therapy of rheumatoid arth ritis have given us important indications for the approach employing what are generally described as "immunomodulators" to control this disease. But this may not be the same type of approach which is desirable for all types of rheumatic conditions. Indeed, even the way which the present range of drugs and other therapies are applied may not be the most effective and safe means of treating different types of arthritic conditions.
Inflammatory Diseases Therapy
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Author : Bonney
language : en
Publisher: Birkhäuser
Release Date : 1993-06
Inflammatory Diseases Therapy written by Bonney and has been published by Birkhäuser this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993-06 with Juvenile Nonfiction categories.
The search for new drugs for inflammatory diseases currently centres on a number of questions. These include the role of biologics in the treatment of rheumatoid arthritis, the possible effectiveness of anti-inflammatory drugs in the treatment of asthma and the feasibility of developing neuropeptide inhibitors as analgesics.
Discovery And Development Of Anti Inflammatory Agents From Natural Products
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Author : Goutam Brahmachari
language : en
Publisher: Elsevier
Release Date : 2019-07-11
Discovery And Development Of Anti Inflammatory Agents From Natural Products written by Goutam Brahmachari and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-11 with Science categories.
Discovery and Development of Anti-inflammatory Agents from Natural Products, the latest volume in the Natural Product Drug Discovery series, presents cutting-edge research advances in the field of bioactive natural products and natural drug formulations, with this volume focusing on molecules of natural origin and their synthetic analogues that have the potential to act against the pathogens responsible for inflammatory diseases. All aspects of each are covered, including isolations and structure elucidations, in vitro and in vivo biological activity, synthetic optimization, investigations of pharmacodynamics and kinetics, and the structure-activity relationships of anti-inflammatory natural products. Written by active researchers and leading experts, this book brings together an overview of current discoveries and trends in this field. It will be a valuable resource for researchers working to discover promising leads for the development of pharmaceuticals in the prevention and treatment of anti-inflammatory diseases. Features contributions from active researchers and leading experts working in medicinal natural products and herbal formulations Includes recent, cutting-edge advances on medicinal natural products, along with preventative therapies for different kinds of inflammation-directed diseases Offers an authoritative source of information on the industrial application of natural products for medicinal purposes
Side Effects Of Anti Inflammatory Drugs
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Author : K. D. Rainsford
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Side Effects Of Anti Inflammatory Drugs written by K. D. Rainsford and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
These two volumes contain the proceedings of a 3 day international meeting held at the University of Cambidge and Queens' College Cambridge from 31st July to 2nd August 1985 on the Side-Effects of Anti-Inflammatory Analgesic Drugs. The first meeting was held in Verona, (Italy) in 1982 and the organisers felt that, with a number of recent developments including the withdrawal of a num ber of new anti-inflammatory drugs, and concern being expressed in the lay and specialist medical press and other media about the safety of these drugs, that it was appropriate to have a second such meeting. The meeting was attended by some 300 delegates and the dis cussion focussed most intently on the recent issues, e. g. the value of adverse drug reaction reporting of the non-steroidal anti inflammatory (NSAI) drugs, certain side-effects associated with particular NSAI drugs, the predictive value of animal models etc. Organising a meeting de novo without outside help would not have been possible without the immensely valuable help given en thusiastically by people and financial assistance given most generously by those pharmaceutical companies listed below. These financial contributions were given despite current economic dif ficulties and moves to restrict the proportion of profits towards educational activities.
Recent Advances In Novel Therapeutic Molecules And Targets For Inflammatory Diseases
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Author : Shuai Wang
language : en
Publisher: Frontiers Media SA
Release Date : 2023-02-01
Recent Advances In Novel Therapeutic Molecules And Targets For Inflammatory Diseases written by Shuai Wang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-02-01 with Science categories.
Side Effects Of Anti Inflammatory Drugs
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Author : K. D. Rainsford
language : en
Publisher: Springer
Release Date : 2012-05-08
Side Effects Of Anti Inflammatory Drugs written by K. D. Rainsford and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-05-08 with Medical categories.
These two volumes contain the proceedings of a 3 day international meeting held at the University of Cambidge and Queens' College Cambridge from 31st July to 2nd August 1985 on the Side-Effects of Anti-Inflammatory Analgesic Drugs. The first meeting was held in Verona, (Italy) in 1982 and the organisers feIt that, with a number of recent developments including the. withdrawal of a num ber of new anti-inflammatory drugs, and concern being expressed in the lay and specialist medical press and other media about the safety of these drugs, that it was appl'Qpriate to have a second such meeting. The meeting was attended by some 300 delegates and the dis cussion focussed most intently on the recent issues, . e. g. the value of adverse drug reaction reporting of the non-. steroidal anti inflammatory (NSAI) drugs, certain side-effects associated with particular NSAI drugs, the predictive value of animal models etc. Organising a meeting de novo without outside help would not have been possible without the immensely valuable help given en thusiastica1ly by people and financial assistance given most generously by those pharmaceutical companies listed below. These financial contributions were given despite current economic dif ficulties and moves to restrict the proportion of profits towards educational actlvities.
Inflammatory Disease Therapy
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Author : Robert J. Bonney
language : en
Publisher: Birkhauser
Release Date : 1993
Inflammatory Disease Therapy written by Robert J. Bonney and has been published by Birkhauser this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Medical categories.
Recent Developments In The Pharmacology Of Inflammatory Mediators
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Author : Iwan L. Bonta
language : en
Publisher: Agents and Actions Supplements
Release Date : 1977
Recent Developments In The Pharmacology Of Inflammatory Mediators written by Iwan L. Bonta and has been published by Agents and Actions Supplements this book supported file pdf, txt, epub, kindle and other format this book has been release on 1977 with Juvenile Nonfiction categories.
In previous studies (1,2) we demonstrated the occurrence of a foetal protein after injury in the rat. This protein, behaving as an acute phase protein, proved to be already known as slow a2 glo bulin (3), or reproduction associated protein (4). Furthermore it is identical to aM foetoprotein (also known as a2FP or aMFP (5) ). This protein is quite different to the well-known a-foetoprotein (aFP), occurring in man and other species during liver carcinoge nesis and some other tumours. aMfoetoprotein (aMFP) is a glycoprotein with a mol.w. of 800.000. It is produced in the liver (6,2) and in the normal adult rat the plasma concentrations are rather low, about 0 - 40 ~g/ml. During fetal development the plasma level in the fetus is much higher (about 6000 ~g/ml), diminishing rapidly after birth to adult levels. But after injury (laparotomy, deep incision, partial hepatectomy followed by regeneration, BaS04 or CdS04 intraperitoneally), plasma levels increase fastly, reaching peak values of 1000 - 8000 ~g/ml after 24 - 48 hrs, declining thereafter gradually. Also very small lesions, as orbital punction, venasection, cannulations, small infections and so on, cause moderate rises of plasma levels up to 80 - 120 ~g/ml. During fetal stage the inflammatory reaction often lacks some of its characteristic features: oedema and infiltration of leucocytes are often rather scanty (7). Also is known that in exudates proteins occur, inhibiting experimen tal inflammations (8,9).