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Recent Advances In Novel Therapeutic Molecules And Targets For Inflammatory Diseases


Recent Advances In Novel Therapeutic Molecules And Targets For Inflammatory Diseases
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Recent Advances In Novel Therapeutic Molecules And Targets For Inflammatory Diseases


Recent Advances In Novel Therapeutic Molecules And Targets For Inflammatory Diseases
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Author : Shuai Wang
language : en
Publisher: Frontiers Media SA
Release Date : 2023-02-01

Recent Advances In Novel Therapeutic Molecules And Targets For Inflammatory Diseases written by Shuai Wang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-02-01 with Science categories.




Novel Molecular Approaches To Anti Inflammatory Therapy


Novel Molecular Approaches To Anti Inflammatory Therapy
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Author : Waldemar Pruzanski
language : en
Publisher: Birkhäuser
Release Date : 1995-02-24

Novel Molecular Approaches To Anti Inflammatory Therapy written by Waldemar Pruzanski and has been published by Birkhäuser this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-02-24 with Medical categories.


In July 1994, the Canadian Inflammation Society in Toronto hosted a symposium entitled "Novel molecular approaches to anti-inflammatory therapy" as a satellite of the xnth International Congress of Pharmacology. For several reasons the above topic was singled out and separated from the general Congress. Major advances have recently been made in the understanding of inflammatory mechanisms. These advances serve as the basis for a new generation of therapeutic agents which may potentially alter our approach to inflammatory processes and infectious diseases. The Satellite Symposium focused on recent advances in diversified fields including arachidonate metabolites, actions of cytokines, chemokines, cellular adhesion molecules and novel molecular approaches in the therapy of inflammation. Scholarly addresses were presented by eminent experts in their respective fields. In this book are included 17 papers which describe in detail novel approaches to the study of inflammation. We hope that this book will serve not only as a summary of present knowledge, but will stimulate both scientists and clinicians to continue their efforts to battle inflammatory diseases. W. Pruzanski, Chair, Publications Committee P. Vadas, Chair, Organizing Committee 1 AAS46 Novel Molecular Approaches to Anti-Inflammatory Theory © 1995 Birkhauser Verlag Basel EOSINOPHIL CHEMOATIRACTANIS GENERATED IN VIYO T. I. Williams, D. A. Griffiths-Iohnson, P. I. lose and P. D. Collins. Department of Applied Pharmacology, National Heart and Lung Institute, Dovehouse Street, London SW3 6LY, United Kingdom.



Advances And Avenues In The Development Of Novel Carriers For Bioactives And Biological Agents


Advances And Avenues In The Development Of Novel Carriers For Bioactives And Biological Agents
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Author : Manju Rawat Singh
language : en
Publisher: Academic Press
Release Date : 2020-04-07

Advances And Avenues In The Development Of Novel Carriers For Bioactives And Biological Agents written by Manju Rawat Singh and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-07 with Business & Economics categories.


Advances and Avenues in the Development of Novel Carriers for Bioactives and Biological Agents provides sound data on the utility of biological and plant-based drugs and describes challenges faced in all aspects offering indispensable strategies to use in the development of bioactive medicines. Bioactive based medications are commonly used throughout the world and have been recognized by physicians and patients for their therapeutic efficacy. Bioactive formulations, including their subordinates and analogs, address 50% of all medicines in clinical practice. Novel bioactive medicine transporters can cure many disorders by both spatial and transitory approaches and have various justifications in medicinal potential. This book presents information on the utility of natural, plant, animal and bioengineered bioactive materials. It is a fundamental source of information and data for pharmacognosists, pharmaceutical analysts, drug transport scientists and pharmacologists working in bioactive medications. Advances information on various bioactive based medications, their sources, clinical consequences and transport strategies Illustrates diverse transport systems for bioactives and derivatives, novel techniques for formulations, targeting strategies and fundamental qualities of developed bioactive carriers, and their safety concerns and standardization Discusses distinctive transport systems, stability, upgraded dissolvability, and enhanced bioavailability of bioactives



Improving And Accelerating Therapeutic Development For Nervous System Disorders


Improving And Accelerating Therapeutic Development For Nervous System Disorders
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2014-02-06

Improving And Accelerating Therapeutic Development For Nervous System Disorders written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-02-06 with Medical categories.


Improving and Accelerating Therapeutic Development for Nervous System Disorders is the summary of a workshop convened by the IOM Forum on Neuroscience and Nervous System Disorders to examine opportunities to accelerate early phases of drug development for nervous system drug discovery. Workshop participants discussed challenges in neuroscience research for enabling faster entry of potential treatments into first-in-human trials, explored how new and emerging tools and technologies may improve the efficiency of research, and considered mechanisms to facilitate a more effective and efficient development pipeline. There are several challenges to the current drug development pipeline for nervous system disorders. The fundamental etiology and pathophysiology of many nervous system disorders are unknown and the brain is inaccessible to study, making it difficult to develop accurate models. Patient heterogeneity is high, disease pathology can occur years to decades before becoming clinically apparent, and diagnostic and treatment biomarkers are lacking. In addition, the lack of validated targets, limitations related to the predictive validity of animal models - the extent to which the model predicts clinical efficacy - and regulatory barriers can also impede translation and drug development for nervous system disorders. Improving and Accelerating Therapeutic Development for Nervous System Disorders identifies avenues for moving directly from cellular models to human trials, minimizing the need for animal models to test efficacy, and discusses the potential benefits and risks of such an approach. This report is a timely discussion of opportunities to improve early drug development with a focus toward preclinical trials.



Alzheimer S Disease Drug Development


Alzheimer S Disease Drug Development
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Author : Jeffrey Cummings
language : en
Publisher: Cambridge University Press
Release Date : 2022-03-31

Alzheimer S Disease Drug Development written by Jeffrey Cummings and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-31 with Business & Economics categories.


Provides a definitive overview of the complex ecosystem facilitating Alzheimer's Disease drug research and development. Demonstrates a drug's journey from in the lab, clinical trial testing, regulatory review, and marketing by pharmaceutical companies. Details the use of artificial intelligence, clinical trial management, and financing models.



Ibd Management Novel Targets And Therapeutic Perspectives


Ibd Management Novel Targets And Therapeutic Perspectives
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Author : Luca Antonioli
language : en
Publisher: Frontiers Media SA
Release Date : 2020-05-28

Ibd Management Novel Targets And Therapeutic Perspectives written by Luca Antonioli and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-05-28 with categories.




Novel Therapeutic Approaches Targeting Oxidative Stress


Novel Therapeutic Approaches Targeting Oxidative Stress
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Author : Pawan Kumar Maurya
language : en
Publisher: Academic Press
Release Date : 2022-02-18

Novel Therapeutic Approaches Targeting Oxidative Stress written by Pawan Kumar Maurya and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-18 with Science categories.


Novel Therapeutic Approaches Targeting Oxidative Stress investigates the role of oxidative stress in disease and explores the latest methods and approaches to targeting oxidative stress for treatment and diagnosis. The book begins with an introduction to oxidative stress and its significance. Subsequent sections cover biochemical methods for detecting free radicals and novel therapeutic approaches for targeting oxidative stress in a number of different diseases. This includes age-related illnesses, neuropsychiatric disorders such as schizophrenia and bipolar disorder, and neurodegenerative diseases like Alzheimer’s and Parkinson’s disease. Novel approaches for targeting oxidative stress in cancer and cardiovascular diseases are also explored. The book then moves on to discuss advances in drug delivery systems and detecting oxidative stress biomarkers using biosensors. It concludes with case studies that illustrate the targeting of oxidative stress and future perspectives. Explores oxidative stress in a variety of diseases, including neurological disorders, cardiovascular diseases, age-related diseases, and cancer Covers a range of therapeutic approaches to target oxidative stress Includes chapters on the application of novel drug delivery systems and diagnostic biosensors to oxidative stress Features case studies illustrating the targeting of oxidative stress



Recent Advances In Potential Biomarkers For Rheumatic Diseases And In Cell Based Therapies In The Management Of Inflammatory Rheumatic Diseases


Recent Advances In Potential Biomarkers For Rheumatic Diseases And In Cell Based Therapies In The Management Of Inflammatory Rheumatic Diseases
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Author : Eric Toussirot
language : en
Publisher: Frontiers Media SA
Release Date : 2022-02-18

Recent Advances In Potential Biomarkers For Rheumatic Diseases And In Cell Based Therapies In The Management Of Inflammatory Rheumatic Diseases written by Eric Toussirot and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-18 with Medical categories.




Molecular Mechanism Of Congenital Heart Disease And Pulmonary Hypertension


Molecular Mechanism Of Congenital Heart Disease And Pulmonary Hypertension
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Author : Toshio Nakanishi
language : en
Publisher: Springer Nature
Release Date : 2020-02-28

Molecular Mechanism Of Congenital Heart Disease And Pulmonary Hypertension written by Toshio Nakanishi and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-02-28 with Medical categories.


This open access book focuses on the molecular mechanism of congenital heart disease and pulmonary hypertension, offering new insights into the development of pulmonary circulation and the ductus arteriosus. It describes in detail the molecular mechanisms involved in the development and morphogenesis of the heart, lungs and ductus arteriosus, covering a range of topics such as gene functions, growth factors, transcription factors and cellular interactions, as well as stem cell engineering technologies. The book also presents recent advances in our understanding of the molecular mechanism of lung development, pulmonary hypertension and molecular regulation of the ductus arteriosus. As such, it is an ideal resource for physicians, scientists and investigators interested in the latest findings on the origins of congenital heart disease and potential future therapies involving pulmonary circulation/hypertension and the ductus arteriosus.



Novel Therapeutic Target And Drug Discovery For Neurological Diseases


Novel Therapeutic Target And Drug Discovery For Neurological Diseases
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Author : Rui Liu
language : en
Publisher: Frontiers Media SA
Release Date : 2022-11-14

Novel Therapeutic Target And Drug Discovery For Neurological Diseases written by Rui Liu and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-14 with Science categories.