Therapeutic Rna Nanotechnology


Therapeutic Rna Nanotechnology
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Therapeutic Rna Nanotechnology


Therapeutic Rna Nanotechnology
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Author : Kirill A. Afonin
language : en
Publisher: CRC Press
Release Date : 2021-07-21

Therapeutic Rna Nanotechnology written by Kirill A. Afonin and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-07-21 with Medical categories.


This collection of research articles and reviews covers the latest work in the design, delivery, dynamic abilities, and immune stimulation of RNA nanoparticles which have driven the utilization of their immunomodulatory properties. The unknown immune properties of nucleic acid nanoparticles have been a major hurdle in their adaptation until the works herein began assessing their structure-activity relationships. This collection chronologically follows the path of investigating the recognition of design components to implementing them into nucleic acid nanostructures. RNA nanotechnology is an emerging platform for therapeutics with increasing clinical relevance as this approach becomes more widely used and approved for the treatment of various diseases. The latest research aims to take advantage of RNA’s modular nature for the design of nanostructures which can interact with their environments to communicate programmed messages with intracellular pathways. In doing so, nanoparticles can be used to elicit or elude responses by the immune system as desired in conjunction with their therapeutic applications.



Rna Nanotechnology And Therapeutics


Rna Nanotechnology And Therapeutics
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Author : Peixuan Guo
language : en
Publisher: CRC Press
Release Date : 2013-07-09

Rna Nanotechnology And Therapeutics written by Peixuan Guo and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-07-09 with Medical categories.


Interest in RNA nanotechnology has increased in recent years as recognition of its potential for applications in nanomedicine has grown. Edited by the world's foremost experts in nanomedicine, this comprehensive, state-of-the-art reference details the latest research developments and challenges in the biophysical and single molecule approaches in R



Rna Nanotechnology And Therapeutics


Rna Nanotechnology And Therapeutics
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Author : Peixuan Guo
language : en
Publisher:
Release Date : 2015

Rna Nanotechnology And Therapeutics written by Peixuan Guo and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with Biotechnology categories.


This volume contains a compilation of techniques and laboratory protocols directly related to RNA nanotechnology and its applications in nanobiotechnology and nanomedicine. The chapters in this book cover a wide range of research methods that can be easily comprehended and carried out in a step-by-step manner by graduate students and postdoctoral fellows from diverse scientific disciplines. Some of the covered topics include various biochemical, biophysical and bioinformatics approaches for analyzing RNA structures and properties; methods to analyze the multi-step assembly process of RNA nanoarchitectures; purification of multifunctional RNA nanoparticles by ultracentrifugation and HPLC; real-time detection of RNA nanoconstructs in vivo; conjugation of imaging, targeting and therapeutic modules to RNA scaffold; and design and characterization of RNA-protein nanostructures. Written in the highly successful Methods of Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubles troubleshooting and avoiding known pitfalls. Cutting-edge and practical, RNA Nanotechnology and Therapeutics: Methods and Protocols propels the field toward new heights by engaging researchers working in the diverse fields of physical, engineering, and life sciences.



Advances In Nanomedicine For The Delivery Of Therapeutic Nucleic Acids


Advances In Nanomedicine For The Delivery Of Therapeutic Nucleic Acids
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Author : Surendra Nimesh
language : en
Publisher: Woodhead Publishing
Release Date : 2017-04-04

Advances In Nanomedicine For The Delivery Of Therapeutic Nucleic Acids written by Surendra Nimesh and has been published by Woodhead Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-04-04 with Science categories.


Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids addresses several issues related to safe and effective delivery of nucleic acids (NAs) using nanoparticles. A further emphasis would be laid on the mechanism of delivery of NAs, the barriers encountered and the strategies adapted to combat them. An exhaustive account of the advantages as well shortcomings of all the delivery vectors being employed in delivery of various NAs will be provided. On final note the regulatory aspects of nanoparticles mediated NA would be discussed, with focus on their clinical relevance. The design and development of nucleic acid-based therapeutics for the treatment of diseases arising from genetic abnormalities has made significant progress over the past few years. NAs have been widely explored for the treatment of cancer and infectious diseases or to block cell proliferation and thereby caused diseases. Advances in synthetic oligonucleotide chemistry resulted in synthesis of NAs that are relatively stable in in vivo environments. However, cellular targeting and intracellular delivery of NAs still remains a challenge. Further development of NA-based therapeutics depends on the progress of safe and effective carriers for systemic administration. Nanomedicine has facilitated availability of vectors with diminished cytotoxicity and enhanced efficacy which are rapidly emerging as systems of choice. These vectors protect NAs from enzymatic degradation by forming condensed complexes along with targeted tissue and cellular delivery. During the past few years, a myriad reports have appeared reporting delivery of NAs mediated by nanoparticles. This book will provide an overview of nanoparticles being employed in the in vitro and in vivo delivery of therapeutically relevant NAs like DNA, siRNA, LNA, PNA, etc. Provides a complete overview of the applicatiosn of nanomedicine in the delivery of nucleic acids, from characterization of nanoparticles, to in vitro and in vivo studies Discusses delivery issues of less well explored nucleic acids, like PNAs, Ribozymes, DNAzymes, etc. Summarizes the current state of research in nucleic acid delivery and underscores the future of nanomedicine in this field



Rna Nanotechnology


Rna Nanotechnology
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Author : Bin Wang
language : en
Publisher: CRC Press
Release Date : 2014-04-02

Rna Nanotechnology written by Bin Wang and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-04-02 with Medical categories.


In the past few decades there has been incredible growth in "bionano"-related research, which has been accompanied by numerous publications in this field. Although various compilations address topics related to deoxyribonucleic acid (DNA) and protein, there are few books that focus on determining the structure of ribonucleic acid (RNA) and using RNA as building blocks to construct nanoarchitectures for biomedical and healthcare applications. RNA Nanotechnology is a comprehensive volume that details both the traditional approaches and the latest developments in the field of RNA-related technology. This book targets a wide audience: a broad introduction provides a solid academic background for students, researchers, and scientists who are unfamiliar with the subject, while the in-depth descriptions and discussions are useful for advanced professionals. The book opens with reviews on the basic aspects of RNA biology, computational approaches for predicting RNA structures, and traditional and emerging experimental approaches for probing RNA structures. This section is followed by explorations of the latest research and discoveries in RNA nanotechnology, including the design and construction of RNA-based nanostructures. The final segment of the book includes descriptions and discussions of the potential biological and therapeutic applications of small RNA molecules, such as small/short interfering RNAs (siRNAs), microRNAs (miRNAs), RNA aptamers, and ribozymes.



Rna Nanostructures


Rna Nanostructures
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Author : Kirill A. Afonin
language : en
Publisher: Humana
Release Date : 2023-09-13

Rna Nanostructures written by Kirill A. Afonin and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-13 with Science categories.


This volume details protocols for computer-assisted design and experimental characterization of RNA nanostructures. Chapters guide readers through RNA nanotechnology, design and characterization of RNA nanostructures, assessment of immunology of nanomaterials, biosensing and drug delivery, various biomedical applications, and delivery approaches for therapeutic RNA nanoparticles. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, RNA Nanostructures: Design, Characterization, and Applications aims to address essential topics and concerns in the growing field of RNA nanotechnology.



Rna Nanotechnology


Rna Nanotechnology
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Author : Bin Wang
language : en
Publisher:
Release Date : 2014

Rna Nanotechnology written by Bin Wang and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with categories.


In the past few decades there has been incredible growth in "bionano"--Related research, which has been accompanied by numerous publications in this field. Although various compilations address topics related to deoxyribonucleic acid (DNA) and protein, there are few books that focus on determining the structure of ribonucleic acid (RNA) and using RNA as building blocks to construct nanoarchitectures for biomedical and healthcare applications. RNA Nanotechnology is a comprehensive volume that details both the traditional approaches and the latest developments in the field of RNA-related technology. This book targets a wide audience: a broad introduction provides a solid academic background for students, researchers, and scientists who are unfamiliar with the subject, while the in-depth descriptions and discussions are useful for advanced professionals. The book opens with reviews on the basic aspects of RNA biology, computational approaches for predicting RNA structures, and traditional and emerging experimental approaches for probing RNA structures. This section is followed by explorations of the latest research and discoveries in RNA nanotechnology, including the design and construction of RNA-based nanostructures. The final segment of the book includes descriptions and discussions of the potential biological and therapeutic applications of small RNA molecules, such as small/short interfering RNAs (siRNAs), microRNAs (miRNAs), RNA aptamers, and ribozymes.



Nanotechnology For The Delivery Of Therapeutic Nucleic Acids


Nanotechnology For The Delivery Of Therapeutic Nucleic Acids
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Author : Dan Peer
language : en
Publisher: CRC Press
Release Date : 2013-03-27

Nanotechnology For The Delivery Of Therapeutic Nucleic Acids written by Dan Peer and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-27 with Medical categories.


Nucleic acid (NA) therapeutics has been extensively studied both in the academia and in the pharmaceutical industry and is still considered the promise for new therapeutic modalities, especially in personalized medicine. The only hurdle that limits the translation of NA therapeutics from an academic idea to the new therapeutic modality is the lack



Pharmaco Biotechnology And Nanotechnology


Pharmaco Biotechnology And Nanotechnology
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Author : Raghu Gogada
language : en
Publisher: Cambridge Scholars Publishing
Release Date : 2022-09-28

Pharmaco Biotechnology And Nanotechnology written by Raghu Gogada and has been published by Cambridge Scholars Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-09-28 with Technology & Engineering categories.


This volume details various interesting aspects of pharmaceutical biotechnology. Some of the contributions here focus on nano-biotechnological aspects of cancer and its detection as nanotechnology is one of the most popular areas of research today. Chapters also discuss biosensors in the area of pharmacology and will serve as a guide for the study of various types of biosensors and their mode of action. The book also considers topics such as pharmacogenetics and nutrigenetics, keeping in mind the recent advancement in biomedical science. Its critical discussion of current research references to molecular pharmacology and molecular biotechnology will allow the reader to decipher the interplay between diet, drugs, and genetic factors for improving human health. The book will be of interest to professional researchers, under-graduate and post-graduate students, and professors, as well as industry practitioners.



Rna Nanotechnology


Rna Nanotechnology
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Author : John Maclane
language : en
Publisher: Createspace Independent Publishing Platform
Release Date : 2017-06-07

Rna Nanotechnology written by John Maclane and has been published by Createspace Independent Publishing Platform this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-06-07 with categories.


In the past few decades there has been incredible growth in "bionano"-related research, which has been accompanied by numerous publications in this field. Although various compilations address topics related to deoxyribonucleic acid (DNA) and protein, there are few books that focus on determining the structure of ribonucleic acid (RNA) and using RNA as building blocks to construct nanoarchitectures for biomedical and healthcare applications. RNA Nanotechnology is a comprehensive volume that details both the traditional approaches and the latest developments in the field of RNA-related technology. This book targets a wide audience: a broad introduction provides a solid academic background for students, researchers, and scientists who are unfamiliar with the subject, while the in-depth descriptions and discussions are useful for advanced professionals. The book opens with reviews on the basic aspects of RNA biology, computational approaches for predicting RNA structures, and traditional and emerging experimental approaches for probing RNA structures. This section is followed by explorations of the latest research and discoveries in RNA nanotechnology, including the design and construction of RNA-based nanostructures. The final segment of the book includes descriptions and discussions of the potential biological and therapeutic applications of small RNA molecules, such as small/short interfering RNAs (siRNAs), microRNAs (miRNAs), RNA aptamers, and ribozymes.