Thrombosis And Cancer
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Thrombosis And Cancer
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Author : Gilles Lugassy
language : en
Publisher: CRC Press
Release Date : 2004-02-23
Thrombosis And Cancer written by Gilles Lugassy and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-02-23 with Medical categories.
This text provides comprehensive and timely coverage of the current knowledge of cancer-associated thrombosis, its pathogenesis, clinical features, prevention, and therapy. It specifically addresses the relationship between hemostatic systems and cancer, thus providing a unique and much needed focus. All of the contributors are acknowledged specialists in their fields and have experience conducting large clinical trials in oncology and thrombosis. Their discussions cover all aspects of the topic, from long-term complications to cancer surgery. It will be of interest to general practitioners, internists, oncologists, hematologists, and all physicians involved in the management of cancer patients.
Thrombosis In Cancer A Medical Professional S Guide To Cancer Associated Thrombosis
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Author : Supratik Rayamajhi
language : en
Publisher: Bentham Science Publishers
Release Date : 2021-05-24
Thrombosis In Cancer A Medical Professional S Guide To Cancer Associated Thrombosis written by Supratik Rayamajhi and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-05-24 with Medical categories.
Ever since the association between cancer and thrombosis was reported by Jean-Baptiste Bouillaud in the early 19th century, cancer-associated thrombosis has remained a challenging domain of cancer management. Thrombosis can at times be a lead to cancer diagnosis, while it often complicates medical situations as a coexisting disorder. In this handbook, the contributors have compiled comprehensive information on the subject to provide the reader a comprehensive review of current medical literature and guidelines for cancer-associated thrombosis. Key Features -clinically oriented text for application in healthcare settings -current, evidence-based literature reviews and references -includes guidelines on VTE prophylaxis, heparin effects and more -includes information about special cases Thrombosis in Cancer: A Medical Professional's Guide to Cancer Associated Thrombosis is an informative handbook for a broad range of readers in medicine, including generalists, residents, and graduate-level trainees.
Cancer Associated Thrombosis
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Author : Alok A. Khorana
language : en
Publisher: CRC Press
Release Date : 2007-09-26
Cancer Associated Thrombosis written by Alok A. Khorana and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-09-26 with Medical categories.
Showcasing the expertise of top-tier specialists who contributed to the newly released guidelines for the care of thrombosis in cancer patients, this exciting guide was written and edited by members of the American Society of Clinical Oncology panel, (ASCO), on the prevention and treatment of cancer-associated thrombosis, among others, and provides
Thrombosis And Hemostasis In Cancer
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Author : Gerald Soff
language : en
Publisher: Springer
Release Date : 2019-07-17
Thrombosis And Hemostasis In Cancer written by Gerald Soff and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-17 with Medical categories.
In this book, leaders in the field explore our current understanding of thrombosis and hemostasis in cancer and address key questions on the subject. Among the topics discussed are the mechanisms that cancers use to activate the coagulation system, and those by means of which an activated coagulation system can lead to more aggressive cancer growth. Clinical chapters examine the role of thrombosis prophylaxis and treatment, central line-associated thrombosis, and cancer-associated hemorrhage. Subsequent chapters deal with the management of chemotherapy-induced thrombocytopenia, anticoagulation in the presence of brain metastases, and other unique challenges in the interaction of thrombosis and hemostasis in cancer. It has been 150 years since Armand Trousseau first described the well-known association between cancer and an increased risk of thrombosis, which may be considered the first paraneoplastic syndrome ever identified. More recently, numerous studies have indicated that activation of the coagulation system by cancer not only increases the likelihood of thrombosis, but is also associated with a more aggressive cancer phenotype. By familiarizing readers with the latest developments in this complex and challenging field, the book offers a valuable resource for scientists and clinicians alike.
Coagulation In Cancer
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Author : David Green
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-04-21
Coagulation In Cancer written by David Green and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-04-21 with Medical categories.
Coagulation in Cancer informs professionals working in the field of cancer about the pathophysiologic mechanisms of cancer-related thrombosis and bleeding. It provides assistance in recognizing the various bleeding and clotting disorders associated with cancer and includes current recommendations for the management of hemorrhage, and prevention and treatment of thrombosis in the patient with malignancy. This volume is a valuable addition to the literature on cancer and coagulation.
Cancer Blood Clots And Bleeding
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Author : Floris Bosch
language : en
Publisher:
Release Date : 2024
Cancer Blood Clots And Bleeding written by Floris Bosch and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024 with categories.
"People with cancer have a very high risk of venous thrombo-embolism (VTE), comprising deep vein thrombosis and pulmonary embolism, compared to people without cancer. Treatment of VTE in people with cancer is complicated since both the bleeding risk and recurrent VTE risk are higher than in people without cancer. In this thesis several studies on the treatment, prevention and etiology of cancer-associated VTE are presented. In part 1 (chapters 2 to 5) studies on the treatment of cancer-associated VTE are discussed. Chapter 2 presents a study in the drug-drug interaction between edoxaban and tamoxifen in women with breast cancer. Chapter 3 is a systematic review and meta-analysis of randomized controlled trials on direct oral anticoagulants (DOAC) versus low-molecular-weight heparin (LMWH) for the treatment of cancer-associated VTE. Chapter 4 discusses risk factors on gastro-intestinal bleeding in patients with VTE and gastro-intestinal cancer on edoxaban. In Chapter 5 the risk of cancer in patients with factor Xa inhibitors is studied in a Danish population cohort study. In part 2 (chapters 6 to 8) studies on the prevention of cancer-associated VTE are discussed. Chapter 6 is a narrative review on primary thromboprophylaxis in ambulatory cancer patients. Chapter 7 is a systematic review and meta-analysis on primary thromboprophylaxis in ambulatory cancer patients with a high risk of VTE. In Chapter 8 we discuss the predictive value of the biomarker GDF-15 for bleeding in patients with thromboprophylaxis in the AVERT trial. In part 3 (chapters 9 to 11) studies on aetiology and epidemiology of cancer-associated VTE are presented. In chapter 9 results of a study on intrinsic pathway activation in patients with pancreatic cancer are reported. Chapter 10 shows a study in tumor gene expression and VTE risk in patients with pancreatic cancer. Chapter 11 is a study on the prevalence of pulmonary embolism in cancer patients on whom autopsy is performed."--
A New Paradigm In The Management Of Thrombosis In Cancer Patients
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Author :
language : en
Publisher:
Release Date : 2006
A New Paradigm In The Management Of Thrombosis In Cancer Patients written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Thrombosis categories.
The Pathophysiology Of Cancer And Thrombosis
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Author : A. J. Roberts
language : en
Publisher:
Release Date : 2009-01-27
The Pathophysiology Of Cancer And Thrombosis written by A. J. Roberts and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-01-27 with categories.
Following major improvements in diagnostic modalities for venous thromboembolism (VTE), interest in the association between cancer and thrombosis has been growing. Due to increased awareness of this association, physicians have become more concerned with finding any concurrent malignant disease, particularly in patients with idiopathic VTE. With the establishment of low-molecular-weight heparin(oid)s (LMWH) as the preferred antithrombotic treatment, a number of studies have revealed an additional advantage of LMWH in patients with cancer, related to the efficacy and safety of therapy but also to a potential beneficial effect on survival. Now, detailed knowledge of the molecular mechanisms that link cancer and thrombosis has reached such a level that new options for diagnostic and therapeutic interventions are beginning to emerge. In this special issue, a group of expert physician-scientists and fundamental scientists in the field of 'cancer and thrombosis' present state-of-the-art summaries of important lines of research into the biology of the interactions between cancer and thrombosis. Their findings reflect the beginning of a revolution in the diagnosis and management of cancer patients at risk of thrombosis and point the way to an ultimate improvement of their care.
Vascular Access In Cancer Patients Clinical Implications
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Author : Knut Taxbro
language : en
Publisher: Linköping University Electronic Press
Release Date : 2019-07-23
Vascular Access In Cancer Patients Clinical Implications written by Knut Taxbro and has been published by Linköping University Electronic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-23 with categories.
Central venous catheters (CVC) are vital for patients receiving chemotherapy not compatible with peripheral infusion. Thousands of centrally and peripherally inserted central venous catheters are inserted into patients with cancer each year. All types of intravascular catheters are associated with complications. These complications may be divided into infectious, thrombotic, mechanical and occlusive events. All of these events have the potential to harm patients and cause additional expense for the health-care system. Furthermore, the above-mentioned complications are largely avoidable through proper patient selection, insertion technique, hygiene precautions and catheter maintenance. Catheter-related infections and deep venous thrombosis are the two most common and feared CVC related complications. Infection in a catheter can cause lifethreatening bacteraemia, and thrombosis can lead to pulmonary embolisation, post-thrombotic syndrome and stenosis of the vessel affected. Many studies describing methods to minimise infectious complications associated with central venous catheters have been carried out. These methods appear to have been implemented in most modern advanced healthcare facilities resulting in a continual decrease in catheter-related infections over the last two decades. New implantation techniques, fewer infections and better catheter materials are likely to have contributed to the reduction in the incidence of catheter-related deep venous thrombosis (CR-DVT). Peripherally inserted central venous catheters (PICC) and subcutaneously implanted vascular access ports (PORT) are two very commonly used catheter devices for delivery of chemotherapy. International guidelines are unclear as to which device to choose due to the paucity of controlled trials. The aim of this thesis was to study complications related to central venous access devices used over long periods of time, usually for the delivery of chemotherapy. Vascular access in cancer patients – clinical implications We prospectively studied PORT complications (Study 1) over a six-month follow- up period. In Study 2, we assessed the number of common CVC-related micro- organisms that are transferred across PORT membrane contaminated by a controlled suspension of micro-organisms when a non-coring access needle is inserted using two different techniques. In the largest randomised controlled trial published on this topic (Study 3), we compared PICC with PORT regarding CRDVT and other catheter-related complications. The economic implications of using PICC or PORT were assessed from health-care system´s perspective (Study 4), using data on adverse events and clinical factors (implantation, treatments and dwell-time) from Study 3. Chemotherapy against various forms of cancer is very common. Implantation of PORT is one of the ten most common surgical procedures in Sweden according to the Swedish Perioperative Register. Hence, the topic in this thesis may be clinically relevant to many patients and their health care providers. We found that the incidence of catheter-related blood stream infection was very low in the cohorts studied. In general, PICCs are associated with significantly more CR-DVTs and adverse events than PORTs. The cost to the health-care system when using PICC is higher than for PORT when complications are included. Given the choice, patients about to commence chemotherapy appear to prefer PORT to PICC. PORT implantation is more painful than PICC insertion, but PICC appears to influence activities of daily life more than PORT.
Clinical Cases In Cardio Oncology
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Author : Atooshe Rohani
language : en
Publisher: Springer Nature
Release Date : 2021-04-26
Clinical Cases In Cardio Oncology written by Atooshe Rohani and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-26 with Medical categories.
This latest book in the Clinical Cases in Cardiology series presents a variety of commonly and rarely encountered cases associated with cardio-oncology. It explores the history of the discipline and each case described features concise practically orientated information on how to appropriately carry out physical examinations and utilize diagnostic tests including electrocardiography and monoclonal antibodies. Practically focused guidance is also provided on how to apply therapeutic techniques and the latest management strategies appropriately. Clinical Cases in Cardio-Oncology provides a concise practically applicable guide of how to diagnose and treat a range of conditions associated with cardio-oncology, making it a critical addition to the literature on the topic and a valuable resource for all medical practitioners who encounter these patients in their day-to-day practice.