Thyroid Hormone Metabolismmolecular Biology And Alternate Pathways
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Thyroid Hormone Metabolismmolecular Biology And Alternate Pathways
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Author : Sing-Yung Wu
language : en
Publisher: CRC Press
Release Date : 1994-07-13
Thyroid Hormone Metabolismmolecular Biology And Alternate Pathways written by Sing-Yung Wu and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-07-13 with Medical categories.
This book gathers some of the most talented and well-informed experts in the field, who not only summarize the recent breakthroughs and new findings, but also shed light on future research. Special emphasis is placed on the exciting new understanding of the molecular structure of one of the major enzymes (type 1 iodothyronine deiodinase) involved in the activation of the thyroid hormone. This breakthrough culminates the major effort in this field around the world. As a result, we can study the regulation of thyroid hormone activation mechanism at the molecular level. Two other important deiodinase enzymes (types II and III) are also reviewed. Alternate pathways of thyroid hormone metabolism represent another major advance. These pathways are associated with a variety of physiological and disease states, including fasting, glucocorticoid excess, fetal development, and inflammatory and non-thyroidal illnesses. The understanding of these pathways assists us to better understand the physiological and biological basis of the disease process and thus to improve clinical management of patients with thyroidal and non-thyroidal illnesses.
Thyroid Hormone Metabolism
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Author : Georg Hennemann
language : en
Publisher: Marcel Dekker
Release Date : 1986
Thyroid Hormone Metabolism written by Georg Hennemann and has been published by Marcel Dekker this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986 with Thyroid homones categories.
Molecular Basis Of Thyroid Hormone Action
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Author : Jack Oppenheimer
language : en
Publisher: Elsevier
Release Date : 2012-12-02
Molecular Basis Of Thyroid Hormone Action written by Jack Oppenheimer and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.
Molecular Basis of Thyroid Hormone Action focuses on the actions of thyroid hormones in eukaryotic cells. This book discusses the profound effects of thyroid hormones on the growth, development, and metabolism of practically all tissues of higher organisms. Organized into 15 chapters, this volume starts with an overview of the kinetic interrelationships of hormone bound to specific receptors and hormone associated with other tissue and plasma pools in living animals. This book then discusses the thyroid hormone receptor, a chromatin-associated protein that appears to mediate the actions of the thyroid hormones in mammalian cells. Other chapters consider the localization of the receptors in chromatin. This book further discusses how thyroid hormones stimulate the accumulation of specific mRNA molecules in cell culture as well as in tissues in vivo. This book is intended for readers who are interested in cell and molecular biology. Endocrinologists will also find this book extremely useful.
The Thyroid Hormones
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Author : Rosalind Pitt-Rivers
language : en
Publisher: Elsevier
Release Date : 2013-10-22
The Thyroid Hormones written by Rosalind Pitt-Rivers and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-22 with Medical categories.
International Series of Monographs on Pure and Applied Biology, Volume 1: The Thyroid Hormones focuses on the reactions, characteristics, and chemistry of thyroid hormones. The selection first offers information on the chemistry of thyroxine, iodinated compounds of the thyroid glands, and biosynthesis of the thyroid hormones. Discussions focus on the constitution of desiodothyroxine, diiodotyrosine, biological significance of the iodothyronines, rate of secretion of the thyroid hormone into the circulation, and formation of thyroxine from diiodotyrosine in vitro. The manuscript then takes a look at the transport and physiological actions of the thyroid hormones. Topics include thyroxine-binding by other serum proteins, extravascular fluids, and tissue proteins, effect on nitrogen and lipid metabolism, growth, maturation, and differentiation, and effect on the cardiovascular system and blood. The book examines the mechanism of action of thyroid hormones, extrathyroidal distribution and metabolism of iodine, and biochemical pathways of thyroid hormone metabolism. The text is a dependable reference for readers interested in the reactions, characteristics, and chemistry of thyroid hormones.
Thyroid Hormone
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Author :
language : en
Publisher: Academic Press
Release Date : 2018-01-18
Thyroid Hormone written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-18 with Science categories.
Thyroid hormone, Volume 106, the latest release in the Vitamins and Hormones series first published in 1943 provides up-to-date information on crystal structures and basic structural studies on neurotrophins and their receptors, neurotrophin functions and the biological actions of neurotrophins related to clinical conditions and disease. This new release focuses on timely topics, including the Nuclear Import and Export of the Thyroid Hormone Receptor, the Thyroid hormone and the white matter of the central nervous system: from development to repair, Thyroid hormone and astrocyte differentiation, and the Molecular Basis of Nongenomic Actions of Thyroid Hormone, amongst other topics. Presents the latest information on thyroid hormone Provides a long-running series that focuses on updates and advances in vitamins and hormones Covers single molecules or diseases that are related to vitamins or hormones, with the topic broadly interpreted to include related substances
Pharmacotherapeutics Of The Thyroid Gland
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Author : A.P. Weetman
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Pharmacotherapeutics Of The Thyroid Gland written by A.P. Weetman and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
All the important pharmacological interactions affecting thyroid function are described in this book. The first section is devoted to the physiology and biochemistry of thyroid disease, putting the pharmacological interactions into perspective. The second section reviews all the important pharmacological effects on thyroid function and also deals with the impact of other environmental agents. The chapters are written by internationally recognised experts and extensively referenced to provide an up-to-date review of the pharmacological interactions important to the thyroid and its diseases.
Oxford Textbook Of Endocrinology And Diabetes
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Author : John A.H. Wass
language : en
Publisher: Oxford University Press
Release Date : 2011-07-28
Oxford Textbook Of Endocrinology And Diabetes written by John A.H. Wass and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-07-28 with Medical categories.
Now in its second edition, the Oxford Textbook of Endocrinology and Diabetes is a fully comprehensive, evidence-based, and highly-valued reference work combining basic science with clinical guidance, and providing first rate advice on diagnosis and treatment.
Pcbs
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Author : Larry G. Hansen
language : en
Publisher: University of Illinois Press
Release Date : 2023-12-11
Pcbs written by Larry G. Hansen and has been published by University of Illinois Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-12-11 with Medical categories.
Though polychlorinated biphenyls (PCBs) have been banned in the United States for more than thirty years, the toxic effects of their presence in local environments continue to be a significant public health concern. PCBs: Human and Environmental Disposition and Toxicology brings together more than fifty established specialists on PCB toxicity to discuss recent trends and specialized investigations of PCB influences on the environment and on humans. Renowned scientists including Paul S. Cooke, Takeshi Nakano, Tomas Trnovec, Deborah C. Rice, Linda S. Birnbaum, and Charles S. Wong present cutting-edge research on Hudson River PCBs, human contamination, homologue profiles, high PCB exposure in Slovakia, and PCB effects on the thyroid hormone, nutrition, and estrogen levels in humans and animals. Focusing on the detection, movement, metabolism, toxicity, remediation, and risk assessment of PCB contamination, this multi-disciplinary study is a valuable resource for regulatory agencies and scientists working with PCBs.
Principles Of Endocrinology And Hormone Action
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Author : Antonino Belfiore
language : en
Publisher: Springer
Release Date : 2018-02-08
Principles Of Endocrinology And Hormone Action written by Antonino Belfiore and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-02-08 with Medical categories.
This volume provides comprehensive coverage of the current knowledge of the physiology of the endocrine system and hormone synthesis and release, transport, and action at the molecular and cellular levels. It presents essential as well as in-depth information of value to both medical students and specialists in Endocrinology, Gynecology, Pediatrics, and Internal Medicine. Although it is well established that the endocrine system regulates essential functions involved in growth, reproduction, and homeostasis, it is increasingly being recognized that this complex regulatory system comprises not only hormones secreted by the classic endocrine glands but also hormones and regulatory factors produced by many organs, and involves extensive crosstalk with the neural and immune system. At the same time, our knowledge of the molecular basis of hormone action has greatly improved. Understanding this complexity of endocrine physiology is crucial to prevent endocrine disorders, to improve the sensitivity of our diagnostic tools, and to provide the rationale for pharmacological, immunological, or genetic interventions. It is such understanding that this book is designed to foster.
Cellular Endocrinology In Health And Disease
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Author : Alfredo Ulloa-Aguirre
language : en
Publisher: Academic Press
Release Date : 2021-02-02
Cellular Endocrinology In Health And Disease written by Alfredo Ulloa-Aguirre and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-02-02 with Science categories.
Cellular Endocrinology in Health and Disease, Second Edition, describes the underlying basis of endocrine function, providing an important tool to understand the fundamentals of endocrine diseases. Delivering a comprehensive review of the basic science of endocrinology, from cell biology to human disease, this work explores and dissects the function of a number of cellular systems. The new edition provides an understanding of how endocrine glands function by integrating information resulting in biological effects on both local and systemic levels, also providing new information on the molecular physiopathogenesis of endocrine neoplasic cells. The new edition expands the most used chapters from the first edition and proposes a series of substitutions and additions to the table of contents. New chapters cover signaling, brown adipose tissue, hypothalamic cell models, cellular basis of insulin resistance, genetics and epigenetics of neuroendocrine tumors, and a series of chapters on endocrine-related cancer. Providing content that crosses disciplines, Cellular Endocrinology in Health and Disease, Second Edition, details how cellular endocrine function contributes to system physiology and mediates endocrine disorders. A methods section proves novel and useful approaches across research focus that will be attractive to medical students, residents, and specialists in the field of endocrinology, as well as to those interested in cellular regulation. Editors Alfredo Ulloa-Aguirre and Ya-Xiong Tao, experts in molecular and cellular aspects of endocrinology, deliver contributions carefully selected for relevance, impact, and clarity of expression from leading field experts Explores endocrine cells biology in normal and pathologic conditions Covers new aspects of endocrine cell function in distinct tissues Provides a view into the biological effect in local and systemic levels 15 new chapters covering the recent developments in the field