Time Domains Of Hypoxia Adaptation Evolutionary Insights And Applications
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Time Domains Of Hypoxia Adaptation Evolutionary Insights And Applications
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Author : Tatum S. Simonson
language : en
Publisher: Frontiers Media SA
Release Date : 2021-12-22
Time Domains Of Hypoxia Adaptation Evolutionary Insights And Applications written by Tatum S. Simonson and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-22 with Science categories.
Time Domains Of Hypoxia Adaptation Evolutionary Insights And Applications Volume Ii
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Author : Tatum S. Simonson
language : en
Publisher: Frontiers Media SA
Release Date : 2023-07-06
Time Domains Of Hypoxia Adaptation Evolutionary Insights And Applications Volume Ii written by Tatum S. Simonson and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-07-06 with Science categories.
The Red Cell Life Cycle From Erythropoiesis To Clearance
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Author : Lars Kaestner
language : en
Publisher: Frontiers Media SA
Release Date : 2019-02-05
The Red Cell Life Cycle From Erythropoiesis To Clearance written by Lars Kaestner and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-02-05 with categories.
The eBook ‘The red cell life-cycle from erythropoiesis to clearance’ continues the discussion of questions like: What are the changes associated with red blood cell maturation, adulthood and senescence? What are the determinants of red blood cell life span and clearance? What are the mechanisms in control of red blood cell mass in healthy humans and patients with various forms of anaemia? Can red blood cells be 'trained' to provide the body with more oxygen during endurance exercises? What are the markers of circulating red blood cell senescence and in cells during storage and transfusion? And what can be learned from various species that developed advanced adaptations to maintain oxygen delivery under stress conditions such as exercising to the limit, diving or living in anaerobic aquatic habitats or at high altitude? Within the approximately 120 days (or 40 in a mouse, or 150-170 in a horse) life span of 'healthy' red blood cells, many cellular properties change leading to aged mixed cell populations in the circulation. Red blood cells seem to be genetically terminated by the time they become red blood cells and the contributions of this eBook increase the understanding of this process. There are surprisingly versatile remodeling processes happening during the red blood cell life span. Numerous disorders are associated with the premature onset of the 'ageing process' of red blood cells. Furthermore, in vitro ageing and/or modifications as well as the slowing down of the modifications is an important issue in transfusion medicine. Many of the molecular mechanisms behind such effects are elucidated in this eBook.
Respiratory Muscle Training
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Author : Alison McConnell
language : en
Publisher: Elsevier Health Sciences
Release Date : 2013-04-18
Respiratory Muscle Training written by Alison McConnell and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-18 with Medical categories.
Respiratory Muscle Training: theory and practice is the world’s first book to provide an "everything-you-need-to-know" guide to respiratory muscle training (RMT). Authored by an internationally-acclaimed expert, it is an evidence-based resource, built upon current scientific knowledge, as well as experience at the cutting-edge of respiratory training in a wide range of settings. The aim of the book is to give readers: 1) an introduction to respiratory physiology and exercise physiology, as well as training theory; 2) an understanding of how disease affects the respiratory muscles and the mechanics of breathing; 3) an insight into the disease-specific, evidence-based benefits of RMT; 4) advice on the application of RMT as a standalone treatment, and as part of a rehabilitation programme; and finally, 5) guidance on the application of functional training techniques to RMT. The book is divided into two parts – theory and practice. Part I provides readers with access to the theoretical building blocks that support practice. It explores the evidence base for RMT as well as the different methods of training respiratory muscles and their respective efficacy. Part II guides the reader through the practical implementation of the most widely validated form of RMT, namely inspiratory muscle resistance training. Finally, over 150 "Functional" RMT exercises are described, which incorporate a stability and/or postural challenge – and address specific movements that provoke dyspnoea. Respiratory Muscle Training: theory and practice is supported by a dedicated website (www.physiobreathe.com), which provides access to the latest information on RMT, as well as video clips of all exercises described in the book. Purchasers will also receive a three-month free trial of the Physiotec software platform (via www.physiotec.ca), which allows clinicians to create bespoke training programmes (including video clips) that can be printed or emailed to patients. Introductory overviews of respiratory and exercise physiology, as well as training theory Comprehensive, up-to-date review of respiratory muscle function, breathing mechanics and RMT Analysis of the interaction between disease and respiratory mechanics, as well as their independent and combined influence upon exercise tolerance Analysis of the rationale and application of RMT to over 20 clinical conditions, e.g., COPD, heart failure, obesity, mechanical ventilation Evidence-based guidance on the implementation of inspiratory muscle resistance training Over 150 functional exercises that incorporate a breathing challenge www.physiobreathe.com - access up-to-date information, video clips of exercises and a three-month free trial of Physiotec’s RMT exercise module (via www.physiotec.ca)
Plant Responses To Hypoxia
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Author : Elena Loreti
language : en
Publisher: MDPI
Release Date : 2021-03-02
Plant Responses To Hypoxia written by Elena Loreti and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-02 with Science categories.
Molecular oxygen deficiency leads to altered cellular metabolism and can dramatically reduce crop productivity. Nearly all crops are negatively affected by a lack of oxygen (hypoxia) due to adverse environmental conditions such as excessive rain and soil waterlogging. Extensive efforts to fully understand how plants sense oxygen deficiency and their ability to respond using different strategies are crucial to increase hypoxia tolerance. Progress in our understanding has been significant in recent years. This topic certainly deserves more attention from the academic community; therefore, we have compiled a series of articles reflecting the advancements made thus far.
Gene Expression And Regulation In Mammalian Cells Transcription Toward The Establishment Of Novel Therapeutics
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Author : Fumiaki Uchiumi
language : en
Publisher:
Release Date : 2018
Gene Expression And Regulation In Mammalian Cells Transcription Toward The Establishment Of Novel Therapeutics written by Fumiaki Uchiumi and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018 with Genetics categories.
Sixty years after the ""central dogma,"" great achievements have been developed in molecular biology. We have also learned the important functions of noncoding RNAs and epigenetic regulations. More importantly, whole genome sequencing and transcriptome analyses enabled us to diagnose specific diseases. This book is not only intended for students and researchers working in laboratory but also physicians and pharmacists. This volume consists of 14 chapters, divided into 4 parts. Each chapter is written by experts investigating biological stresses, epigenetic regulation, and functions of transcription factors in human diseases. All articles presented in this volume by excellent investigators provide new insights into the studies in transcriptional control in mammalian cells and will inspire us to develop or establish novel therapeutics against human diseases.
Oxygen Sensing
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Author :
language : en
Publisher: Elsevier
Release Date : 2004-05-10
Oxygen Sensing written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-05-10 with Science categories.
The ability of cells to sense and respond to changes in oxygenation underlies a multitude of developmental, physiological, and pathological processes. This volume provides a comprehensive compendium of experimental approaches to the study of oxygen sensing in 48 chapters that are written by leaders in their fields.
Mosaic Evolution Of Subterranean Mammals
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Author : Eviatar Nevo
language : en
Publisher: Oxford University Press, USA
Release Date : 1999
Mosaic Evolution Of Subterranean Mammals written by Eviatar Nevo and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with Burrowing animals categories.
Subterranean life exists within an extraordinary environment and has evolved among different groups of mammals all over the globe. With relatively constant temperature, few opportunities to meet organisms other than the immediate family, and a completely different sensory environment, the evolution of such life is fascinating. Locomotion, communication, food-finding, navigation, circadian rhythms, and indeed the whole of the animals' physiology may be specialized to cope with life underground. And from burrowing to blindness, magnetic communication to the weird bee-like eusociality of blind mole rats, specialization has been extreme and has led to speciation in a whole range of new contexts. That the subterranean way of life occurs in different species of mammals across the globe has provided scientists with one of nature's best studied global evolutionary demonstrations of adaptive radiation and speciation. The revolution in molecular biology that has occurred over the last ten years has massively expanded these horizons, allowing scientists to explore, map, and clone the genes underlying the basis of adaptation and speciation and translate their fascinating structural and functional evolution into genes and genomic language. This book draws together the burgeoning literature about all aspects of the biology of subterranean mammals. Beginning with their evolutionary history and the processes that led to the subterranean way of life, the author reviews ecology, behavior, and physiology within the context of the highly stressful subterranean context, considers the specialization that has evolved in response, and then compares the eleven families of extant subterranean mammals. The incredible circumstances surrounding subterranean mammals present a unique, global, 'natural experiment' in evolution that has implications throughout biology. As such, this broad survey will stand as an invaluable reference to evolutionary biologists, ecologists, and molecular biologists for years to come.
The Hadal Zone
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Author : Alan Jamieson
language : en
Publisher: Cambridge University Press
Release Date : 2015-01-29
The Hadal Zone written by Alan Jamieson and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-01-29 with Science categories.
A long overdue collation of all that is known about life in the trenches and the hadal communities therein.
From Neurons To Neighborhoods
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2000-11-13
From Neurons To Neighborhoods written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-11-13 with Social Science categories.
How we raise young children is one of today's most highly personalized and sharply politicized issues, in part because each of us can claim some level of "expertise." The debate has intensified as discoveries about our development-in the womb and in the first months and years-have reached the popular media. How can we use our burgeoning knowledge to assure the well-being of all young children, for their own sake as well as for the sake of our nation? Drawing from new findings, this book presents important conclusions about nature-versus-nurture, the impact of being born into a working family, the effect of politics on programs for children, the costs and benefits of intervention, and other issues. The committee issues a series of challenges to decision makers regarding the quality of child care, issues of racial and ethnic diversity, the integration of children's cognitive and emotional development, and more. Authoritative yet accessible, From Neurons to Neighborhoods presents the evidence about "brain wiring" and how kids learn to speak, think, and regulate their behavior. It examines the effect of the climate-family, child care, community-within which the child grows.