Tissue Oxygen Utilization
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Regulation Of Tissue Oxygenation Second Edition
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Author : Roland N. Pittman
language : en
Publisher: Biota Publishing
Release Date : 2016-08-18
Regulation Of Tissue Oxygenation Second Edition written by Roland N. Pittman and has been published by Biota Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-18 with Medical categories.
This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.
Gupta And Gelb S Essentials Of Neuroanesthesia And Neurointensive Care
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Author : Arun Gupta
language : en
Publisher: Cambridge University Press
Release Date : 2018-06-21
Gupta And Gelb S Essentials Of Neuroanesthesia And Neurointensive Care written by Arun Gupta and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-21 with Medical categories.
This second edition presents core clinical neuroanesthesia and neurointensive care knowledge in a practical, user-friendly format.
Cardiovascular Physiology Concepts
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Author : Richard E. Klabunde
language : en
Publisher: Lippincott Williams & Wilkins
Release Date : 2005
Cardiovascular Physiology Concepts written by Richard E. Klabunde and has been published by Lippincott Williams & Wilkins this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Medical categories.
This uniquely readable, compact, and concise monograph lays a foundation of knowledge of the underlying concepts of normal cardiovascular function. Students welcome the book's broad overview as a practical partner or alternative to a more mechanistically oriented approach or an encyclopedic physiology text. Especially clear explanations, ample illustrations, a helpful glossary of terms, tutorials, and chapter-opening learning objectives provide superb guidance for self-directed learning and help fill the gap in many of today's abbreviated physiology blocks. A focus on well-established cardiovascular principles reflects recent, widely accepted cardiovascular research. The supplemental CD-ROM is an interactive, dynamically linked version of the book, which is organized by normal cardiovascular function and cardiac disease. Students may begin a path of questioning with, for example, a disease condition and then pursue background information through a series of links. Students can also link to the author's regularly updated Web site for additional clinical information.
Tissue Oxygen Utilization
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Author : Guillermo Gutierrez
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Tissue Oxygen Utilization written by Guillermo Gutierrez and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Disturbances in peripheral O extraction can be produced in dogs treated with 2 endotoxin and thereby provide an opportunity to test theories for the origin of pathological O supply dependency or to try different treatment modalities. The 2 most serious deficiency in the current animal models is the inability to mimic the increased O demand that is observed in patients at 02 delivery rates in excess of 2 normal. A particular feature of this increased O demand is that it apparently does 2 not stimulate increased 02 extraction, although the limitation in O extraction has 2 not been explored in patients by lowering 02 supply, for obvious reasons. At least two possibilities to account for increased 02 demand could be investigated in animal models, however. The amount of 02 that is utilized in extramitochondrial pathways, which is normally on the order of 10%, may be greatly increased in ARDS and sepsis by O radical formation. There is presently no information 2 concerning how much 02 might be used in this way. Another strong possibility is that mitochondrial injury, perhaps as a result of 02 radical formation, uncouples oxidative phosphorylation. Some evidence presently in the literature supports this idea [19]. Indeed, the association of increased blood lactate levels with higher than expected 02 demands makes uncoupling a very attractive hypothesis that warrants further investigation in animal models using such agents as 2,4-dinitrophenol. References 1.
Oxygen Transport To Tissue Xvi
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Author : Michael C. Hogan
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Oxygen Transport To Tissue Xvi written by Michael C. Hogan and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
Since its inception in 1973, The International Society on Oxygen Transport to Tissue (ISOTT) has provided a unique forum to facilitate and encourage scientific interaction and debate. Welcoming scientists and clinicians from a broad spectrum of disciplines, each with their own particular skills and expertise, ISOTT unites them under the common theme of oxygen transport. The successful blend of scientific presentations and informal discussion which characterizes ISOTT is epitomized best by the many fundamental discoveries and technical advancements which it has spawned. The breadth and strengths of The Society's scientific base promotes the rapid progression of ideas from theoretical concepts to rigorous scientific testing and often, ultimately to the clinical arena. Each publication of the ISOTT proceedings has been recognized by Science Citation Index listing and the papers frequently establish scientific precedents and become considered as standard works in their respective fields. The 21st ISOTT Meeting was held in San Diego from August 14th through August 18th, 1993. The San Diego Meeting attracted about 150 registrants and 40 accompanying persons. Ten state-of-the-art lectures were presented by international experts in ~ transport and there were in addition two symposia -one dealing with assessment of tissue hypoxia and the other with functional heterogeneity in different organ systems. There were 100 free communications, consisting of posters accompanied by an abbreviated oral summary. All manuscripts were reviewed by the Editors for form and content, but as is customary for the ISOTT proceedings, rigorous scientific peer review was not undertaken.
Applied Cardiovascular Physiology
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Author : Michael Pinsky
language : en
Publisher: Springer
Release Date : 1997-03-07
Applied Cardiovascular Physiology written by Michael Pinsky and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-03-07 with Medical categories.
A concise yet complete overview of the treatment of cardiovascular instability in the critically ill patient. The authors consider all aspects, ranging from basic physiology and pathophysiology to diagnostic tools and established and novel forms of therapy. The whole is rounded off with an integration of these principles into a series of clinically relevant scenarios.
Oxford Textbook Of Critical Care
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Author : Andrew Roy Webb
language : en
Publisher: Oxford University Press
Release Date : 2016
Oxford Textbook Of Critical Care written by Andrew Roy Webb and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016 with Medical categories.
Oxford Textbook of Critical Care, second edition, addresses all aspects of adult intensive care management. Taking a unique a problem-orientated approach, this text is a key reference source for clinical issues in the intensive care unit.
Basics Of Blood Management
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Author : Petra Seeber
language : en
Publisher: John Wiley & Sons
Release Date : 2008-04-15
Basics Of Blood Management written by Petra Seeber and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-04-15 with Medical categories.
Commended in the Haematology category at the British MedicalAssociation Book Awards 2008 This unique and practical book introduces the reader to theconcept of blood management and explains how to improve patientoutcomes by avoiding undue blood loss, enhancing thepatient’s own blood, effective management of anemia andcoagulopathy. Basics of Blood Management is the first bookdedicated to blood management, a multidisciplinary andmultimodality concept that focuses on patient outcome. A practical and comprehensive text on the new and excitingfield of blood management Takes an international perspective, covering conditionsencountered in developing and industrial countries Covers all areas of organization, methods and tools Gives the reader an understanding of the concept and philosophyof blood management Provides clinical scenarios and exercises that help the readerto adapt information for their location Whether you are an early practising clinician in hematology,transfusion, critical care, anesthesiology, surgery or internalmedicine, a nursing specialist, trainee or other member of themultidisciplinary blood management team, this book will answer allyour questions about blood management as an aid in improvingpatient outcome.
Monitoring Tissue Perfusion And Oxygenation An Issue Of Critical Nursing Clinics
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Author : Shannan Hamlin
language : en
Publisher: Elsevier Health Sciences
Release Date : 2014-09-28
Monitoring Tissue Perfusion And Oxygenation An Issue Of Critical Nursing Clinics written by Shannan Hamlin and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-09-28 with Medical categories.
Critical care clinicians must be knowledgeable about the anatomic, physiologic, and biochemical processes that are critical to the restoration of a functioning microvascular affecting organ perfusion. These basic physiologic processes critical to tissue perfusion and cellular oxygenation are presented in this issue on Monitoring Tissue Perfusion and Oxygenation. A working knowledge of oxygen delivery and oxygen consumption at the microvascular level will provide critical information needed for clinicians to continuously question the adequacy of tissue perfusion given our current lack of microvascular bedside monitoring.
Clinical Aspects Of O2 Transport And Tissue Oxygenation
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Author : K. Reinhart
language : en
Publisher: Springer
Release Date : 2013-12-21
Clinical Aspects Of O2 Transport And Tissue Oxygenation written by K. Reinhart and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-21 with Medical categories.
All aspects of oxygen transport and tissue oxygenation that are relevant in clinical medicine are covered in this monograph. Experts from basic science as well as clinical research provide information that improves understanding of how to treat O2-transport disturbances in daily practice. Special interest is focussed on the question of supply dependency of O2-uptake and its role in multi-organ failure in the critically ill. Other topics are the clinical monitoring of O2-transport and O2-utilisation, oxygen toxicity, and the role of O2-radicals and the reperfusion syndrome in organ transplantation and cardiopulmonary resuscitation.