Total Marrow Irradiation
DOWNLOAD
Download Total Marrow Irradiation PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Total Marrow Irradiation book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Total Marrow Irradiation
DOWNLOAD
Author : Susanta Kumar Hui
language : en
Publisher: Frontiers Media SA
Release Date : 2023-07-26
Total Marrow Irradiation written by Susanta Kumar Hui and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-07-26 with Medical categories.
Total Marrow Irradiation
DOWNLOAD
Author : Jeffrey Y. C. Wong
language : en
Publisher: Springer Nature
Release Date : 2020-02-29
Total Marrow Irradiation written by Jeffrey Y. C. Wong and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-02-29 with Medical categories.
This book, written by a team of international experts, concisely reviews the rationale and clinical application of image-guided total marrow irradiation, a rapidly emerging area in radiation oncology and hematopoietic cell transplantation. The aim is to provide the practicing radiation oncologist, hematologist, medical physicist, and bone marrow transplant researcher with a fundamental understanding of key aspects and an appreciation of the increasing significance of total marrow irradiation as conditioning for bone marrow transplantation. Detailed attention is paid to the impacts of recent advances in radiation therapy technology, functional PET and MRI, and understanding of the response of bone marrow to radiation. Full consideration is also given to the ways in which technological advances in image-guided radiation therapy have created new opportunities to treat bone marrow transplant patients with limited transplant options due to advanced disease, age, or co-morbidities. Further topics covered include the ways in which cancer stem cells and the marrow microenvironment influence response to radiation therapy and the implementation of new-generation predictive radiobiologic factors in the clinic.
Total Marrow Irradiation
DOWNLOAD
Author : Jeffrey Y. C. Wong
language : en
Publisher: Springer
Release Date : 2021-03-01
Total Marrow Irradiation written by Jeffrey Y. C. Wong and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-01 with Medical categories.
This book, written by a team of international experts, concisely reviews the rationale and clinical application of image-guided total marrow irradiation, a rapidly emerging area in radiation oncology and hematopoietic cell transplantation. The aim is to provide the practicing radiation oncologist, hematologist, medical physicist, and bone marrow transplant researcher with a fundamental understanding of key aspects and an appreciation of the increasing significance of total marrow irradiation as conditioning for bone marrow transplantation. Detailed attention is paid to the impacts of recent advances in radiation therapy technology, functional PET and MRI, and understanding of the response of bone marrow to radiation. Full consideration is also given to the ways in which technological advances in image-guided radiation therapy have created new opportunities to treat bone marrow transplant patients with limited transplant options due to advanced disease, age, or co-morbidities. Further topics covered include the ways in which cancer stem cells and the marrow microenvironment influence response to radiation therapy and the implementation of new-generation predictive radiobiologic factors in the clinic.
Contemporary Bone Marrow Transplantation
DOWNLOAD
Author : Mammen Chandy
language : en
Publisher: Springer
Release Date : 2021-03-25
Contemporary Bone Marrow Transplantation written by Mammen Chandy and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-25 with Medical categories.
Bone Marrow transplantation or Hematopoietic stem cell transplantation is a life saving procedure in a number of diseases,hematological and non hematological, which fail alternative medical management or have no other treatment options. It has transformed the lives of thousands of patients and their families around the world battling with fatal or debilitating diseases.There are many unique aspects of bone marrow transplantation which makes it very different from solid organ transplants. There is an enormous amount of research going on in this field both at clinical and basic science levels.With the rapidly changing world and field of transplantation, there is a need for an authoritative and up to date resource for transplant professionals. This book titled Contemporary Bone Marrow Transplantation aims to be a reference text comprehensively covering various facets of hematopoietic stem cell transplants with latest insights about the technique and basic science behind it . The book is the product of collective effort of transplant professionals round the world, and will reflect their experience as well as the current standard of care practices in Stem cell transplantation.The book will be divided into different sections focusing on the basic science of bone marrow transplant, the technical aspects of the procedure itself and the supportive care of transplant patients.There will also be a section each on epidemiology, upcoming trends and also case studies , which will discuss real case scenarios from the experience of the authors, to illustrate the practical challenges in managing bone marrow transplant recipients.
Response Of Different Species To Total Body Irradiation
DOWNLOAD
Author : J.J. Broerse
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Response Of Different Species To Total Body Irradiation written by J.J. Broerse and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
J.J. Broerse, Radiobiological Institute TNO, Rijswijk, The Netherlands, and T .J. MacVittie, Armed Forces Radiobiology Research Institute, Bethesda, MD, USA. During the past decade, relatively few new studies have been initiated on the response of different species to high-dose, total-body irradia tion. For information on the LDSO/30d (the dose which produces 50 percent lethality within 30 days), one is generally referred to the older literature (e. g., Bond, Fliedner and Archambeau, 1965). Compari son of experimental data reveals considerable variations in LDSD values even after total-body irradiation with conventional X rays, ranging from 4 to 6 Gy in the monkey, 7.1 to 9 Gy in the rat and from 6.4 to 9 Gy in the mouse (see also Hall, 1978). Part of the discrepancy in the LDso values can possibly be attributed to inadequacies in the dosimetry procedures and exposure arrangements employed. As far as clinical experience is concerned, there is now an appreciable amount of information available about the effect of total body irradiation as a conditioning treatment for bone marrow transplan tation in patients suffering from leukaemia or aplastic anaemia. The results from different centres, including the incidence of complications such as radiation pneumonitis, are considerably different. This can part I y be connected with the application of different radiation sched ules: large single dose versus fractionated or protracted irradiation.
Childhood Acute Lymphoblastic Leukemia
DOWNLOAD
Author : Ajay Vora
language : en
Publisher: Springer
Release Date : 2017-04-21
Childhood Acute Lymphoblastic Leukemia written by Ajay Vora and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-04-21 with Medical categories.
This book provides a comprehensive and up-to-date review of all aspects of childhood Acute Lymphoblastic Leukemia, from basic biology to supportive care. It offers new insights into the genetic pre-disposition to the condition and discusses how response to early therapy and its basic biology are utilized to develop new prognostic stratification systems and target therapy. Readers will learn about current treatment and outcomes, such as immunotherapy and targeted therapy approaches. Supportive care and management of the condition in resource poor countries are also discussed in detail. This is an indispensable guide for research and laboratory scientists, pediatric hematologists as well as specialist nurses involved in the care of childhood leukemia.
A Guide To Bone Marrow Transplantation
DOWNLOAD
Author : Hans-Joachim Deeg
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
A Guide To Bone Marrow Transplantation written by Hans-Joachim Deeg and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
In the late 1940s investigators observed that mice given supralethai doses of total body irradiation were protected by infusion of viable spleen or marrow cells following irradiation, and that this was accomplished by hemopoietic reconsti tution with donor cells as proven using genetic markers. If a similar approach could be applied to humans, it should be possible to treat leukemia patients with any dose of chemoradiotherapy as far as nonmarrow toxicity permitted, and then rescue them by marrow transplantation. Early clinical attempts were gen erally unsuccessful, mostly due to a lack of knowledge of histocompatibility antigens and appropriate supportive care. These areas developed rather quickly during the 1960s, and for almost two decades now clinical marrow transplan tation has been carried out with increasing success. After initially using only bone marrow from HLA indentical siblings, the field has expanded rapidly to incorporate HLA nonidentical related donors, and recently even marrow from unrelated volunteer donors. Furthermore, since for numerous patients who oth erwise could benefit from transplantation a donor cannot be identified, there has been a growing interest in using the patient's own (autologous) bone marrow. Our understanding of the principles of transplantation and our knowledge of the potential risks and benefits have quickly grown. At times it is difficult, however, to decide what is the best option for a given patient.
Evaluation Of The Factors Mediating The Survival Of Primates Receiving Total Body X Irradiation And Bone Marrow Transplantation
DOWNLOAD
Author : Arthur Stuart Hall
language : en
Publisher:
Release Date : 1966
Evaluation Of The Factors Mediating The Survival Of Primates Receiving Total Body X Irradiation And Bone Marrow Transplantation written by Arthur Stuart Hall and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1966 with Bone marrow categories.
Modification Of X Radiation Lethality By Autologous Marrow Infusion In Dogs
DOWNLOAD
Author : E. L. Alpen
language : en
Publisher:
Release Date : 1958
Modification Of X Radiation Lethality By Autologous Marrow Infusion In Dogs written by E. L. Alpen and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1958 with Bone marrow categories.
Bone Marrow Transplantation And Other Treatment After Radiation Injury
DOWNLOAD
Author : H. Balner
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Bone Marrow Transplantation And Other Treatment After Radiation Injury written by H. Balner and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Acute radiation injury in man has been amply reviewed in the past decades (1-8). Information for those reviews was mainly derived from the Hiroshima and Nagasaki experience (3), from radiation accidents as a con sequence of testing nuclear weapons and the application of nuclear energy (9-13) and from the intentional irradiation of patients, mostly for the treatment of malignancies and/or as conditioning for transplantation (14-20). Further, a large body of data derived from animal experimentation has led to cautious extrapolations to the human situation (14). An elaborate review dealing with early somatic effects of radiation in a man was published by UNSCEAR ) in 1962 (2). It was supplemented in 1969 with a similar document dealing mostly with radiation-induced chromosome aberra tions, the effects of radiation on the nervous system and, radio-active contamination of the environment by nuclear testing (21). In a more recent UNSCEAR report (1972) the main topics were genetic effects, carcinogenesis and effects of radiation on the immune response (22). The early effects of radiation in man were also expertly and comprehensively reviewed in a report by the United States National Research Council in 1967 (23).