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Total Steroid Synthesis


Total Steroid Synthesis
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Total Steroid Synthesis


Total Steroid Synthesis
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Author : A. A. Akhrem
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Total Steroid Synthesis written by A. A. Akhrem and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.


Since the appearance of the Russian edition of this monograph (1967), the main tendencies of the development of total synfuesis have not changed. The accelerated accumulation of experimental material is continuing, mainly in the form of the improvement of already-existing synthesis schemes. The main new advance is the development of asymmetric syn theses with intermediates that have made it possible to avoid the main dis advantage of total synthesis - the formation of racemic final compounds. The most important work that has appeared since the appearance of the Russian edition is given in an Appendix to the book. Apart from this, only a very slight rearrangement of the material and of some of the schemes has been carried out for the American edition. A. A. Akhrem Yu. A. Titov Moscow, July 1968 v Preface to the Russian Edition Steroids are one of the most interesting and most widely distributed and, at the same time, one of the most structurally complex groups of natural compounds. In spite of this, the great theoretical and practical importance of steroids for biology and medicine has led to very intensive scientific research work on their synthesis. The numerous methods for obtaining steroids developed at the present time can be divided into four main groups: isolation from natural sources, microbiological synthesis, partial synthesis from natural raw material already containing the steroid skeleton, and, finally, total chemical synthesis from precursors of com paratively simple structure.



Total Steroid Synthesis


Total Steroid Synthesis
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Author : Afanasii A. Akhrem
language : en
Publisher:
Release Date : 1970

Total Steroid Synthesis written by Afanasii A. Akhrem and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1970 with categories.




Total Synthesis Of Steroids


Total Synthesis Of Steroids
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Author : Robert T. Blickenstaff
language : en
Publisher: Academic Press
Release Date : 2013-10-22

Total Synthesis Of Steroids written by Robert T. Blickenstaff and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-22 with Science categories.


Organic Chemistry, Volume 30: Total Synthesis of Steroids provides an overall view of steroid total synthesis, including the general approaches, special problems, stereochemical complexities, expansion or contraction of rings, and insertion of hetero atoms. The book discusses the process of designing total syntheses; the biogenetic-like steroid synthesis, including cyclization of terminal epoxides as well as the total synthesis from nonepoxide precursors; and the synthesis of equilenin, estrone, bisdehydrodoisynolic acid, 18,19-bisnorprogesterone, 19-norpregnanes, and heterocyclic steroids. The text also describes the application of ABD intermediates in the Torgov synthesis; the synthesis of carbocyclics and thiasteroids; and the synthesis from p-anisylcyclohexanes and from C-5, C-8 bridged intermediates. The synthesis based on the type of reaction used in the condensation of the A fragment with the CD portion, as well as the methods of total synthesis in the preparation of 8-azasteroids and 8,13-diazasteroids are also considered. The book further tackles the synthesis of epiandrosterone, cortisone, aldosterone, 3ß-hydroxy-5a-pregnan-20-one, latifoline, conessine, and ring C aromatic steroids; the synthesis of trans-benzohydrindane derivatives and other common derivatives; and the synthesis of CD intermediates. Chemists, biochemists, and people involved in the study of steroid total syntheses will find the book invaluable.



Total Steroid Synthesis By Afanasii A Akhrem And Yur A Titov Translated Fromrussian By B J Hazzard


Total Steroid Synthesis By Afanasii A Akhrem And Yur A Titov Translated Fromrussian By B J Hazzard
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Author : Afanasiĭ Andreevich Akhrem
language : en
Publisher:
Release Date :

Total Steroid Synthesis By Afanasii A Akhrem And Yur A Titov Translated Fromrussian By B J Hazzard written by Afanasiĭ Andreevich Akhrem and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on with Steroids categories.




Introduction To Steroid Chemistry


Introduction To Steroid Chemistry
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Author : J. R. Hanson
language : en
Publisher: Elsevier
Release Date : 2016-06-23

Introduction To Steroid Chemistry written by J. R. Hanson and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-06-23 with Science categories.


Introduction to Steroid Chemistry is a six-chapter introductory text of the analysis, conformation, and production of steroids. After providing a brief overview of steroid chemistry, this book goes on discussing the application of physical methods to the analysis of structural and stereochemical correlations in steroids, such as UV, infrared, NMR, and mass spectroscopy, optical rotary dispersion, and circular dichroism. The subsequent two chapters describe the influence of steroid conformation and molecular rearrangements on reactions rates and reaction products. The remaining chapters explore the improvements in the synthesis of the estrogenic hormones and the biosynthetic pathways and metabolism of cholesterol. This book will be of value to general and organic chemists, biochemists, and research workers in related subjects.



An Approach To The Total Synthesis Of Steroids


An Approach To The Total Synthesis Of Steroids
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Author : MICHAEL CHAYKOVSKY
language : en
Publisher:
Release Date : 1961

An Approach To The Total Synthesis Of Steroids written by MICHAEL CHAYKOVSKY and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1961 with categories.




Total Synthesis Of Steroids


Total Synthesis Of Steroids
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Author : Afanasiĭ Andreevich Akhrem
language : en
Publisher:
Release Date : 1969

Total Synthesis Of Steroids written by Afanasiĭ Andreevich Akhrem and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1969 with Steroids categories.




An Approach To Steroid Total Synthesis


An Approach To Steroid Total Synthesis
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Author : Thomas Charles McKenzie
language : en
Publisher:
Release Date : 1971

An Approach To Steroid Total Synthesis written by Thomas Charles McKenzie and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1971 with Steroid hormones categories.




Studies On The Total Synthesis Of Steroids Via Androsta 8 14 Diene Derivatives


Studies On The Total Synthesis Of Steroids Via Androsta 8 14 Diene Derivatives
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Author : James Brian Heather
language : en
Publisher:
Release Date : 1972

Studies On The Total Synthesis Of Steroids Via Androsta 8 14 Diene Derivatives written by James Brian Heather and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1972 with categories.




Studies Of New Approaches To The Total Synthesis Of Steroids


Studies Of New Approaches To The Total Synthesis Of Steroids
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Author : Geoffrey L. Burge
language : en
Publisher:
Release Date : 1983

Studies Of New Approaches To The Total Synthesis Of Steroids written by Geoffrey L. Burge and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1983 with Steroids categories.