Total Synthesis Of Natural Products The Chiron Approach
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Total Synthesis Of Natural Products The Chiron Approach
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Author : Stephen Hanessian
language : en
Publisher: Pergamon
Release Date : 1983
Total Synthesis Of Natural Products The Chiron Approach written by Stephen Hanessian and has been published by Pergamon this book supported file pdf, txt, epub, kindle and other format this book has been release on 1983 with Science categories.
The Total Synthesis Of Natural Products
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Author :
language : en
Publisher:
Release Date : 1988
The Total Synthesis Of Natural Products written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with categories.
Design And Strategy In Organic Synthesis
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Author : Stephen Hanessian
language : en
Publisher: Wiley-VCH
Release Date : 2013-09-03
Design And Strategy In Organic Synthesis written by Stephen Hanessian and has been published by Wiley-VCH this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-09-03 with Science categories.
This long-awaited graduate level book, written by one of the world's leading organic chemists in collaboration with two of his former and present coworkers, adopts a refreshingly unique approach to synthesis planning and execution. Following an introductory look at the concept of synthesis, the authors discuss the Why, What, and How of organic synthesis as they apply to natural products. Although emphasis is on the Chiron Approach utilizing amino-acids, carbohydrates, hydroxy acids, terpenes, lactones and other naturally occurring small molecules as starting materials, catalytic asymmetric methods are also included as a corollary whenever relevant. A must-have source of first class information for everyone working in organic synthesis, be it in academia or industry. With a foreword by Larry E. Overman and David W. C. MacMillan
Efficiency In Natural Product Total Synthesis
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Author : Pei-Qiang Huang
language : en
Publisher: John Wiley & Sons
Release Date : 2018-07-24
Efficiency In Natural Product Total Synthesis written by Pei-Qiang Huang and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-07-24 with Science categories.
Uniting the key organic topics of total synthesis and efficient synthetic methodologies, this book clearly overviews synthetic strategies and tactics applied in total synthesis, demonstrating how the total synthesis of natural products enables scientific and drug discovery. • Focuses on efficiency, a fundamental and important issue in natural products synthesis that makes natural product synthesis a powerful tool in biological and pharmaceutical science • Describes new methods like organocatalysis, multicomponent and cascade reactions, and biomimetic synthesis • Appeals to graduate students with two sections at the end of each chapter illustrating key reactions, strategies, tactics, and concepts; and good but unfinished total synthesis (synthesis of core structure) before the last section • Compiles examples of solid phase synthesis and continuing flow chemistry-based total synthesis which are very relevant and attractive to industry R&D professionals
The Total Synthesis Of Natural Products Volume 7
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Author : John ApSimon
language : en
Publisher: John Wiley & Sons
Release Date : 2009-09-22
The Total Synthesis Of Natural Products Volume 7 written by John ApSimon and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-09-22 with Science categories.
The appearance of the seventh volume of The Total Synthesis of Natural Products signals the continued health of the art and science of organic synthesis. This new volume contains a chapter updating monoterpene synthesis and reviews the newer areas of leukotrienes and macro-cyclic lactones. The Total Synthesis of Natural Products, Volume Seven forms an integral part of the invaluable working reference begun in Volumes One through Six, to which chemists may turn for the available data on the total synthesis of complex molecules. Lessons learned from the synthetic challenges presented here by various natural products will serve as a sound base for this continually evolving field.
Total Synthesis Of Natural Products
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Author : Jie Jack Li
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-14
Total Synthesis Of Natural Products written by Jie Jack Li and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-14 with Science categories.
'Total Synthesis of Natural Products' is written and edited by some of today's leaders in organic chemistry. Eleven chapters cover a range of natural products, from steroids to alkaloids. Each chapter contains an introduction to the natural product in question, descriptions of its biological and pharmacological properties and outlines of total synthesis procedures already carried out. Particular emphasis is placed on novel methodologies developed by the respective authors and their research groups. This text is ideal for graduate and advanced undergraduate students, as well as organic chemists in academia and industry.
From Biosynthesis To Total Synthesis
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Author : Alexandros L. Zografos
language : en
Publisher: John Wiley & Sons
Release Date : 2016-04-18
From Biosynthesis To Total Synthesis written by Alexandros L. Zografos and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-18 with Science categories.
Focusing on biosynthesis, this book provides readers with approaches and methodologies for modern organic synthesis. By discussing major biosynthetic pathways and their chemical reactions, transformations, and natural products applications; it links biosynthetic mechanisms and more efficient total synthesis. • Describes four major biosynthetic pathways (acetate, mevalonate, shikimic acid, and mixed pathways and alkaloids) and their related mechanisms • Covers reactions, tactics, and strategies for chemical transformations, linking biosynthetic processes and total synthesis • Includes strategies for optimal synthetic plans and introduces a modern molecular approach to natural product synthesis and applications • Acts as a key reference for industry and academic readers looking to advance knowledge in classical total synthesis, organic synthesis, and future directions in the field
The Way Of Synthesis
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Author : Tomas Hudlicky
language : en
Publisher: Wiley-VCH
Release Date : 2007-09-04
The Way Of Synthesis written by Tomas Hudlicky and has been published by Wiley-VCH this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-09-04 with Science categories.
This two-colored textbook presents not only synthetic ways to design organic compounds, it also contains a compilation of the most important total synthesis of the last 50 years with a comparative view of multiple designs for the same targets. It explains different tactics and strategies, making it easy to apply to many problems, regardless of the synthetic question in hand. Following a historical view of the evolution of synthesis, the book goes on to look at principles and issues impacting synthesis and design as well as principles and issues of methods. The sections on comparative design cover classics in terpenes and alkaloid synthesis, while a further section covers such miscellaneous syntheses as Maytansine, Palytoxin, Brevetoxin B and Indinavir. The whole is rounded off with a look at future perspectives and, what makes this textbook extraordinairy, with personal recollections of the chemists, who synthesized these fascinating compounds. With its attractive layout highlighting key parts and tactics using a second color, this is a useful tool for organic chemists, lecturers and students in chemistry, as well as those working in the chemical industry. "I think, as will many organic chemists, that the Hudlicky book will be the Bible of synthetic organic chemistry, the past, the present and the future. A hallmark publication." (Victor Snieckus)
The Total Synthesis Of Natural Products Volume 6
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Author : John ApSimon
language : en
Publisher: John Wiley & Sons
Release Date : 2009-09-22
The Total Synthesis Of Natural Products Volume 6 written by John ApSimon and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-09-22 with Science categories.
The sixth volume of The Total Synthesis of Natural Products continues editor John ApSimon's exploration of one of the most promising areas for the future development of organic chemistry: synthesis. ApSimon has compiled the first definitive reference source of successful synthetic approaches to a wide variety of natural products. This new volume considers the total synthesis of triterpenes, carbohydrates, aromatic steroids, pyrrole pigments and genes first reported during the period from 1972 through 1982 in this series. The Total Synthesis of Natural Products, Volume Six forms an integral part of the invaluable working reference begun in Volumes One through Five, to which chemists may turn for the available data on the total synthesis of complex molecules. Lessons learned from the synthetic challenges presented here by various natural products will serve as a sound base for this continually evolving field.
Retrosynthetic Analysis And Synthesis Of Natural Products 1
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Author : Olivier Piva
language : en
Publisher: John Wiley & Sons
Release Date : 2019-09-19
Retrosynthetic Analysis And Synthesis Of Natural Products 1 written by Olivier Piva and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-19 with Science categories.
For chemists, attempting to mimic nature by synthesizing complex natural products from raw material is a challenge that is fraught with pitfalls. To tackle this unique but potentially rewarding task, researchers can rely on well-established reactions and methods of practice, or apply their own synthesis methods to verify their potential. Whatever the goal and its complexity, there are multiple ways of achieving it. We must now establish a strategic and effective plan that requires the minimum number of steps, but lends itself to widespread use. This book is structured around the study of a dozen target products (butyrolactone, macrolide, indole compound, cyclobutanic terpene, spiro- and polycyclic derivatives, etc.). For each product, the different disconnections are presented and the associated syntheses are analyzed step by step. The key reactions are described explicitly, followed by diagrams showing the range of impact of certain transformations. This set of data alone is conducive to understanding syntheses and indulging in this difficult, but worthwhile activity.