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Towards A New 3rs Era In Experimental Research


Towards A New 3rs Era In Experimental Research
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Towards A New 3rs Era In Experimental Research


Towards A New 3rs Era In Experimental Research
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Author : Christopher R. Cederroth
language : en
Publisher: Frontiers Media SA
Release Date : 2024-04-29

Towards A New 3rs Era In Experimental Research written by Christopher R. Cederroth and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-04-29 with Medical categories.


With the persisting need of animal experimentation for fundamental and applied research, the relevance and importance of the 3Rs Principle cannot be ignored. The 3Rs Principle was put forward over 50 years ago, providing an essential framework for more humane animal experimentation in research. In this half-century the research landscape within which this principle is applied has dramatically changed and evolved, with ever more emerging venues to explore for 3Rs advancement and implementation.



Animal Experimentation Working Towards A Paradigm Change


Animal Experimentation Working Towards A Paradigm Change
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Author : Kathrin Herrmann
language : en
Publisher: BRILL
Release Date : 2019-04-30

Animal Experimentation Working Towards A Paradigm Change written by Kathrin Herrmann and has been published by BRILL this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-30 with Philosophy categories.


Animal experimentation has been one of the most controversial areas of animal use, mainly due to the intentional harms inflicted upon animals for the sake of hoped-for benefits in humans. Despite this rationale for continued animal experimentation, shortcomings of this practice have become increasingly more apparent and well-documented. However, these limitations are not yet widely known or appreciated, and there is a danger that they may simply be ignored. The 51 experts who have contributed to Animal Experimentation: Working Towards a Paradigm Change critically review current animal use in science, present new and innovative non-animal approaches to address urgent scientific questions, and offer a roadmap towards an animal-free world of science.



The Principles Of Humane Experimental Technique


The Principles Of Humane Experimental Technique
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Author : William Moy Stratton Russell
language : en
Publisher: Hyperion Books
Release Date : 1992

The Principles Of Humane Experimental Technique written by William Moy Stratton Russell and has been published by Hyperion Books this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with Nature categories.




International Animal Research Regulations


International Animal Research Regulations
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2012-06-26

International Animal Research Regulations written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-06-26 with Science categories.


Animals are widely used in neuroscience research to explore biological mechanisms of nervous system function, to identify the genetic basis of disease states, and to provide models of human disorders and diseases for the development of new treatments. To ensure the humane care and use of animals, numerous laws, policies, and regulations are in place governing the use of animals in research, and certain animal regulations have implications specific to neuroscience research. To consider animal research regulations from a global perspective, the IOM Forum on Neuroscience and Nervous System Disorders, in collaboration with the National Research Council and the Institute for Laboratory Animal Research, held a workshop in Buckinghamshire, UK, July 26-27, 2011. The workshop brought together neuroscientists, legal scholars, administrators, and other key stakeholders to discuss current and emerging trends in animal regulations as they apply to the neurosciences. This document summarizes the workshop.



The Ufaw Handbook On The Care And Management Of Laboratory And Other Research Animals


The Ufaw Handbook On The Care And Management Of Laboratory And Other Research Animals
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Author : Robert C. Hubrecht
language : en
Publisher: John Wiley & Sons
Release Date : 2010-01-19

The Ufaw Handbook On The Care And Management Of Laboratory And Other Research Animals written by Robert C. Hubrecht and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-01-19 with Medical categories.


The seminal reference on the care of laboratory and captiveanimals, The UFAW Handbook on the Care and Management ofLaboratory and Other Research Animals is a must-have for anyoneworking in this field. The UFAW Handbook has been thedefinitive text since 1947. Written for an international audience,it contains contributions from experts from around the world. The book focuses on best practice principles throughout, providingcomprehensive coverage, with all chapters being peer reviewed byanonymous referees. As well as addressing the husbandry oflaboratory animals, the content is also of great value to zoos andaquaria. Changes for the eighth edition: Revised and updated to reflect developments since publicationof the previous edition. New chapters on areas of growing concern, including: the 3Rs;phenotyping; statistics and experimental design; welfareassessment; legislation; training of people caring for lab animals;and euthanasia. All material combined into one volume for ease ofreference. This book is published on behalf of UFAW (The UniversitiesFederation for Animal Welfare), with whom we also publish theUFAW/Wiley-Blackwell Animal Welfare Book Series. This majorseries of books provides an authoritative source ofinformation on worldwide developments, current thinking and bestpractice in the field of animal welfare science and technology. Fordetails of all of the titles in the series see ahref="http://www.wiley.com/go/ufaw"www.wiley.com/go/ufaw/a.



Management Of Animal Care And Use Programs In Research Education And Testing


Management Of Animal Care And Use Programs In Research Education And Testing
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Author : Robert H. Weichbrod
language : en
Publisher: CRC Press
Release Date : 2017-09-07

Management Of Animal Care And Use Programs In Research Education And Testing written by Robert H. Weichbrod and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-07 with Medical categories.


AAP Prose Award Finalist 2018/19 Management of Animal Care and Use Programs in Research, Education, and Testing, Second Edition is the extensively expanded revision of the popular Management of Laboratory Animal Care and Use Programs book published earlier this century. Following in the footsteps of the first edition, this revision serves as a first line management resource, providing for strong advocacy for advancing quality animal welfare and science worldwide, and continues as a valuable seminal reference for those engaged in all types of programs involving animal care and use. The new edition has more than doubled the number of chapters in the original volume to present a more comprehensive overview of the current breadth and depth of the field with applicability to an international audience. Readers are provided with the latest information and resource and reference material from authors who are noted experts in their field. The book: - Emphasizes the importance of developing a collaborative culture of care within an animal care and use program and provides information about how behavioral management through animal training can play an integral role in a veterinary health program - Provides a new section on Environment and Housing, containing chapters that focus on management considerations of housing and enrichment delineated by species - Expands coverage of regulatory oversight and compliance, assessment, and assurance issues and processes, including a greater discussion of globalization and harmonizing cultural and regulatory issues - Includes more in-depth treatment throughout the book of critical topics in program management, physical plant, animal health, and husbandry. Biomedical research using animals requires administrators and managers who are knowledgeable and highly skilled. They must adapt to the complexity of rapidly-changing technologies, balance research goals with a thorough understanding of regulatory requirements and guidelines, and know how to work with a multi-generational, multi-cultural workforce. This book is the ideal resource for these professionals. It also serves as an indispensable resource text for certification exams and credentialing boards for a multitude of professional societies Co-publishers on the second edition are: ACLAM (American College of Laboratory Animal Medicine); ECLAM (European College of Laboratory Animal Medicine); IACLAM (International Colleges of Laboratory Animal Medicine); JCLAM (Japanese College of Laboratory Animal Medicine); KCLAM (Korean College of Laboratory Animal Medicine); CALAS (Canadian Association of Laboratory Animal Medicine); LAMA (Laboratory Animal Management Association); and IAT (Institute of Animal Technology).



The International Encyclopedia Of Primatology 3 Volume Set


The International Encyclopedia Of Primatology 3 Volume Set
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Author : Agustín Fuentes
language : en
Publisher: John Wiley & Sons
Release Date : 2017-04-24

The International Encyclopedia Of Primatology 3 Volume Set written by Agustín Fuentes and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-04-24 with Social Science categories.


The International Encyclopedia of Primatology represents the first comprehensive encyclopedic reference focusing on the behaviour, biology, ecology, evolution, genetics, and taxonomy of human and non-human primates. Represents the first comprehensive encyclopedic reference relating to primatology Features more than 450 entries covering topics ranging from the taxonomy, history, behaviour, ecology, captive management and diseases of primates to their use in research, cognition, conservation, and representations in literature Includes coverage of the basic scientific concepts that underlie each topic, along with the latest advances in the field Highly accessible to undergraduate and graduate students in primatology, anthropology, and the medical, biological and zoological sciences Essential reference for academics, researchers and commercial and conservation organizations This work is also available as an online resource at www.encyclopediaofprimatology.com



Reducing Refining And Replacing The Use Of Animals In Toxicity Testing


Reducing Refining And Replacing The Use Of Animals In Toxicity Testing
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Author : David G. Allen
language : en
Publisher: Royal Society of Chemistry
Release Date : 2013

Reducing Refining And Replacing The Use Of Animals In Toxicity Testing written by David G. Allen and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with Medical categories.


This thought-provoking book describes the ever-expanding "toolbox" of methods now available to reduce, refine, or replace animal usage in toxicity testing.



Advances In Animal Experimentation And Modeling


Advances In Animal Experimentation And Modeling
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Author : Ranbir Chander Sobti
language : en
Publisher: Academic Press
Release Date : 2021-12-08

Advances In Animal Experimentation And Modeling written by Ranbir Chander Sobti and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-08 with Science categories.


Exploration in Laboratory Animal Sciences Understanding Life Phenomena updates our knowledge about the newer technologies such as molecular biology, genomics including sequencing, proteomics, transcriptomics, cell culture, stem cell culture, transgenesis and their translation to understand systematics and phylogeny of laboratory animals at molecular level. In seven sections Exploration in Laboratory Animal Sciences Understanding Life Phenomena resolves issues of conservation, applications in environment monitoring, production of drugs and others. Comparative research has enabled use of domestic animal models that translate the advances in basic biosciences to the schemes for human welfare including medicine. Molecular geneticists are unravelling the complexities of mammalian genes and the field of biotechnology is maturing at a fast pace. Additionally, research focused on immunology and animal behavior offer new insight into ways of enhancing animal welfare. The rise in consumption of animal proteins in addition to the challenges of sustaining our natural resources has given animal scientists a vast array of opportunities to engage in integrative systems-based research for meeting the challenges that behold us. Exploration in Laboratory Animal Sciences Understanding Life Phenomena also discusses the manipulation of animals as factories for the production of safe foods, drugs, and sensors and others to meet the contemporary challenges faced by mankind in the new world order created by pandemic of Covid 19. It also includes several chapters on the causation and management of certain diseases and impact of microbes on life. Provides insight to newer and futuristic technologies to understand disease process and drug design by animal models Addresses a wide variety of species and covers a wide variety of topics (such as animal species, the laboratory setting, regulatory guidelines, and ethical considerations) to fully prepare for work with all types of animals Gives a perspective on laboratory animal use that allows to explain the benefits of animal use as required by veterinary technology program accreditation procedure Includes examples of animal bio-technological techniques (including stem cell and tissue engineering) for their applications to humanity Offers new insight into ways of enhancing animal welfare by the inclusion of research results focused on immunology and laboratory animal behavior



The Ethics Of Animal Research


The Ethics Of Animal Research
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Author : Jeremy R. Garrett
language : en
Publisher: MIT Press
Release Date : 2012-03-30

The Ethics Of Animal Research written by Jeremy R. Garrett and has been published by MIT Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-03-30 with Medical categories.


A balanced, accessible discussion of whether and on what grounds animal research can be ethically justified. An estimated 100 million nonhuman vertebrates worldwide—including primates, dogs, cats, rabbits, hamsters, birds, rats, and mice—are bred, captured, or otherwise acquired every year for research purposes. Much of this research is seriously detrimental to the welfare of these animals, causing pain, distress, injury, or death. This book explores the ethical controversies that have arisen over animal research, examining closely the complex scientific, philosophical, moral, and legal issues involved. Defenders of animal research face a twofold challenge: they must make a compelling case for the unique benefits offered by animal research; and they must provide a rationale for why these benefits justify treating animal subjects in ways that would be unacceptable for human subjects. This challenge is at the heart of the book. Some contributors argue that it can be met fairly easily; others argue that it can never be met; still others argue that it can sometimes be met, although not necessarily easily. Their essays consider how moral theory can be brought to bear on the practical ethical questions raised by animal research, examine the new challenges raised by the emerging possibilities of biotechnology, and consider how to achieve a more productive dialogue on this polarizing subject. The book's careful blending of theoretical and practical considerations and its balanced arguments make it valuable for instructors as well as for scholars and practitioners.