Towards Reverse Engineering Gene Regulatory Networks

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Towards Reverse Engineering Gene Regulatory Networks

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Author : Thomas Schlitt
language : en
Publisher:
Release Date : 2004

Towards Reverse Engineering Gene Regulatory Networks written by Thomas Schlitt and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with categories.

Reverse Engineering Of Regulatory Networks

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Author : Sudip Mandal
language : en
Publisher: Springer Nature
Release Date : 2023-10-06

Reverse Engineering Of Regulatory Networks written by Sudip Mandal and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-10-06 with Technology & Engineering categories.

This volume details the development of updated dry lab and wet lab based methods for the reconstruction of Gene regulatory networks (GRN). Chapters guide readers through culprit genes, in-silico drug discovery techniques, genome-wide ChIP-X data, high-Throughput Transcriptomic Data Exome Sequencing, Next-Generation Sequencing, Fuorescence Spectroscopy, data analysis in Bioinformatics, Computational Biology, and S-system based modeling of GRN. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Reverse Engineering of Regulatory Networks aims to be a useful and practical guide to new researchers and experts looking to expand their knowledge.

Handbook Of Research On Computational Methodologies In Gene Regulatory Networks

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Author : Das, Sanjoy
language : en
Publisher: IGI Global
Release Date : 2009-10-31

Handbook Of Research On Computational Methodologies In Gene Regulatory Networks written by Das, Sanjoy and has been published by IGI Global this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-10-31 with Computers categories.

"This book focuses on methods widely used in modeling gene networks including structure discovery, learning, and optimization"--Provided by publisher.

Probabilistic Boolean Networks

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Author : Ilya Shmulevich
language : en
Publisher: SIAM
Release Date : 2010-01-01

Probabilistic Boolean Networks written by Ilya Shmulevich and has been published by SIAM this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-01-01 with Mathematics categories.

This is the first comprehensive treatment of probabilistic Boolean networks (PBNs), an important model class for studying genetic regulatory networks. This book covers basic model properties, including the relationships between network structure and dynamics, steady-state analysis, and relationships to other model classes." "Researchers in mathematics, computer science, and engineering are exposed to important applications in systems biology and presented with ample opportunities for developing new approaches and methods. The book is also appropriate for advanced undergraduates, graduate students, and scientists working in the fields of computational biology, genomic signal processing, control and systems theory, and computer science.

Analysis Of Deterministic Cyclic Gene Regulatory Network Models With Delays

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Author : Mehmet Eren Ahsen
language : en
Publisher: Birkhäuser
Release Date : 2015-02-25

Analysis Of Deterministic Cyclic Gene Regulatory Network Models With Delays written by Mehmet Eren Ahsen and has been published by Birkhäuser this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-02-25 with Science categories.

This brief examines a deterministic, ODE-based model for gene regulatory networks (GRN) that incorporates nonlinearities and time-delayed feedback. An introductory chapter provides some insights into molecular biology and GRNs. The mathematical tools necessary for studying the GRN model are then reviewed, in particular Hill functions and Schwarzian derivatives. One chapter is devoted to the analysis of GRNs under negative feedback with time delays and a special case of a homogenous GRN is considered. Asymptotic stability analysis of GRNs under positive feedback is then considered in a separate chapter, in which conditions leading to bi-stability are derived. Graduate and advanced undergraduate students and researchers in control engineering, applied mathematics, systems biology and synthetic biology will find this brief to be a clear and concise introduction to the modeling and analysis of GRNs.

Proceedings Of The International Conference On Artificial Intelligence And Computer Vision Aicv2020

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Author : Aboul-Ella Hassanien
language : en
Publisher: Springer Nature
Release Date : 2020-03-23

Proceedings Of The International Conference On Artificial Intelligence And Computer Vision Aicv2020 written by Aboul-Ella Hassanien and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-23 with Technology & Engineering categories.

This book presents the proceedings of the 1st International Conference on Artificial Intelligence and Computer Visions (AICV 2020), which took place in Cairo, Egypt, from April 8 to 10, 2020. This international conference, which highlighted essential research and developments in the fields of artificial intelligence and computer visions, was organized by the Scientific Research Group in Egypt (SRGE). The book is divided into sections, covering the following topics: swarm-based optimization mining and data analysis, deep learning and applications, machine learning and applications, image processing and computer vision, intelligent systems and applications, and intelligent networks.

Evolutionary Computation In Gene Regulatory Network Research

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Author : Hitoshi Iba
language : en
Publisher: John Wiley & Sons
Release Date : 2016-01-20

Evolutionary Computation In Gene Regulatory Network Research written by Hitoshi Iba and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-01-20 with Computers categories.

Introducing a handbook for gene regulatory network research using evolutionary computation, with applications for computer scientists, computational and system biologists This book is a step-by-step guideline for research in gene regulatory networks (GRN) using evolutionary computation (EC). The book is organized into four parts that deliver materials in a way equally attractive for a reader with training in computation or biology. Each of these sections, authored by well-known researchers and experienced practitioners, provides the relevant materials for the interested readers. The first part of this book contains an introductory background to the field. The second part presents the EC approaches for analysis and reconstruction of GRN from gene expression data. The third part of this book covers the contemporary advancements in the automatic construction of gene regulatory and reaction networks and gives direction and guidelines for future research. Finally, the last part of this book focuses on applications of GRNs with EC in other fields, such as design, engineering and robotics. • Provides a reference for current and future research in gene regulatory networks (GRN) using evolutionary computation (EC) • Covers sub-domains of GRN research using EC, such as expression profile analysis, reverse engineering, GRN evolution, applications • Contains useful contents for courses in gene regulatory networks, systems biology, computational biology, and synthetic biology • Delivers state-of-the-art research in genetic algorithms, genetic programming, and swarm intelligence Evolutionary Computation in Gene Regulatory Network Research is a reference for researchers and professionals in computer science, systems biology, and bioinformatics, as well as upper undergraduate, graduate, and postgraduate students. Hitoshi Iba is a Professor in the Department of Information and Communication Engineering, Graduate School of Information Science and Technology, at the University of Tokyo, Toyko, Japan. He is an Associate Editor of the IEEE Transactions on Evolutionary Computation and the journal of Genetic Programming and Evolvable Machines. Nasimul Noman is a lecturer in the School of Electrical Engineering and Computer Science at the University of Newcastle, NSW, Australia. From 2002 to 2012 he was a faculty member at the University of Dhaka, Bangladesh. Noman is an Editor of the BioMed Research International journal. His research interests include computational biology, synthetic biology, and bioinformatics.

Systems Biology

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Author : Aleš Prokop
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-08-28

Systems Biology written by Aleš Prokop and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-08-28 with Medical categories.

Growth in the pharmaceutical market has slowed down – almost to a standstill. One reason is that governments and other payers are cutting costs in a faltering world economy. But a more fundamental problem is the failure of major companies to discover, develop and market new drugs. Major drugs losing patent protection or being withdrawn from the market are simply not being replaced by new therapies – the pharmaceutical market model is no longer functioning effectively and most pharmaceutical companies are failing to produce the innovation needed for success. This multi-authored new book looks at a vital strategy which can bring innovation to a market in need of new ideas and new products: Systems Biology (SB). Modeling is a significant task of systems biology. SB aims to develop and use efficient algorithms, data structures, visualization and communication tools to orchestrate the integration of large quantities of biological data with the goal of computer modeling. It involves the use of computer simulations of biological systems, such as the networks of metabolites comprise signal transduction pathways and gene regulatory networks to both analyze and visualize the complex connections of these cellular processes. SB involves a series of operational protocols used for performing research, namely a cycle composed of theoretical, analytic or computational modeling to propose specific testable hypotheses about a biological system, experimental validation, and then using the newly acquired quantitative description of cells or cell processes to refine the computational model or theory.

Springer Handbook Of Bio Neuro Informatics

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Author : Nikola Kasabov
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-30

Springer Handbook Of Bio Neuro Informatics written by Nikola Kasabov and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-30 with Technology & Engineering categories.

The Springer Handbook of Bio-/Neuro-Informatics is the first published book in one volume that explains together the basics and the state-of-the-art of two major science disciplines in their interaction and mutual relationship, namely: information sciences, bioinformatics and neuroinformatics. Bioinformatics is the area of science which is concerned with the information processes in biology and the development and applications of methods, tools and systems for storing and processing of biological information thus facilitating new knowledge discovery. Neuroinformatics is the area of science which is concerned with the information processes in biology and the development and applications of methods, tools and systems for storing and processing of biological information thus facilitating new knowledge discovery. The text contains 62 chapters organized in 12 parts, 6 of them covering topics from information science and bioinformatics, and 6 cover topics from information science and neuroinformatics. Each chapter consists of three main sections: introduction to the subject area, presentation of methods and advanced and future developments. The Springer Handbook of Bio-/Neuroinformatics can be used as both a textbook and as a reference for postgraduate study and advanced research in these areas. The target audience includes students, scientists, and practitioners from the areas of information, biological and neurosciences. With Forewords by Shun-ichi Amari of the Brain Science Institute, RIKEN, Saitama and Karlheinz Meier of the University of Heidelberg, Kirchhoff-Institute of Physics and Co-Director of the Human Brain Project.

Research In Computational Molecular Biology

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Author : Satoru Miyano
language : en
Publisher: Springer Science & Business Media
Release Date : 2005-04-28

Research In Computational Molecular Biology written by Satoru Miyano and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-04-28 with Computers categories.

This volume contains the papers presented at the 9th Annual International Conference on Research in Computational Molecular Biology (RECOMB 2005), which was held in Cambridge, Massachusetts, on May 14–18, 2005. The RECOMB conference series was started in 1997 by Sorin Istrail, Pavel Pevzner and Michael Waterman. The list of previous meetings is shown below in the s- tion “Previous RECOMB Meetings. ” RECOMB 2005 was hosted by the Broad Institute of MIT and Harvard, and Boston University’s Center for Advanced - nomic Technology, and was excellently organized by the Organizing Committee Co-chairs Jill Mesirov and Simon Kasif. This year, 217 papers were submitted, of which the Program Committee - lected 39 for presentation at the meeting and inclusion in this proceedings. Each submission was refereed by at least three members of the Program Committee. After the completion of the referees’ reports, an extensive Web-based discussion took place for making decisions. From RECOMB 2005, the Steering Committee decided to publish the proceedings as a volume of Lecture Notes in Bioinf- matics (LNBI) for which the founders of RECOMB are also the editors. The prominent volume number LNBI 3500 was assigned to this proceedings. The RECOMB conference series is closely associated with the Journal of Compu- tional Biology which traditionally publishes special issues devoted to presenting full versions of selected conference papers. The RECOMB Program Committee consistedof42members,aslistedonaseparatepage. Iwouldliketothank the RECOMB 2005 Program Committee members for their dedication and hard work.