Toxicological Testing Handbook

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Toxicological Testing Handbook

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Author : Jacobson-Kram David
language : en
Publisher: CRC Press
Release Date : 2000-11-21

Toxicological Testing Handbook written by Jacobson-Kram David and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-11-21 with Medical categories.

Designed to aid toxicology testing study design, this text provides data on issues such as species selection, dose level and dosing regimes, animal models, routes of exposure, statistical evaluation, data interpretation, fulfillment of regulatory requirements, and adherence to good laboratory practices.

Toxicological Testing Handbook

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Author : David Jacobson-Kram
language : en
Publisher: CRC Press
Release Date : 2016-04-19

Toxicological Testing Handbook written by David Jacobson-Kram and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-19 with Medical categories.

Furnishing essential data on all areas of toxicity testing, this Second Edition provides guidance on the design and evaluation of product safety studies to help ensure regulatory acceptance. Every chapter highlights regulatory requirements specific to the United States, Europe, and Japan, and in addition to expanded information on da

A Comprehensive Guide To Toxicology In Preclinical Drug Development

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Author : Ali S. Faqi
language : en
Publisher: Academic Press
Release Date : 2012-10-18

A Comprehensive Guide To Toxicology In Preclinical Drug Development written by Ali S. Faqi and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-10-18 with Medical categories.

A Comprehensive Guide to Toxicology in Preclinical Drug Development is a resource for toxicologists in industry and regulatory settings, as well as directors working in contract resource organizations, who need a thorough understanding of the drug development process. Incorporating real-life case studies and examples, the book is a practical guide that outlines day-to-day activities and experiences in preclinical toxicology. This multi-contributed reference provides a detailed picture of the complex and highly interrelated activities of preclinical toxicology in both small molecules and biologics. The book discusses discovery toxicology and the international guidelines for safety evaluation, and presents traditional and nontraditional toxicology models. Chapters cover development of vaccines, oncology drugs, botanic drugs, monoclonal antibodies, and more, as well as study development and personnel, the role of imaging in preclinical evaluation, and supporting materials for IND applications. By incorporating the latest research in this area and featuring practical scenarios, this reference is a complete and actionable guide to all aspects of preclinical drug testing. - Chapters written by world-renowned contributors who are experts in their fields - Includes the latest research in preclinical drug testing and international guidelines - Covers preclinical toxicology in small molecules and biologics in one single source

Handbook Of Toxicology

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Author : Michael J. Derelanko
language : en
Publisher: CRC Press
Release Date : 2001-08-29

Handbook Of Toxicology written by Michael J. Derelanko and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-08-29 with Medical categories.

LOCATE FREQUENTLY USED INFORMATION EASILY AND QUICKLY Working in the laboratory or office, you use a diverse assortment of basic information to design, conduct, and interpret toxicology studies and to perform risk assessments. The Second Edition of the best-selling Handbook of Toxicology gives you the information you need in a single referen

Handbook Of Toxicology Third Edition

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Author : Michael J. Derelanko
language : en
Publisher: CRC Press
Release Date : 2014-03-07

Handbook Of Toxicology Third Edition written by Michael J. Derelanko and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-03-07 with Law categories.

The Handbook of Toxicology, Third Edition provides an updated practical reference source for practicing toxicologists in the pharmaceutical and chemical industries, contract laboratories, regulatory agencies, and academia. Written by experts in their specific toxicology fields, the chapters provide both fundamental and applied information. Topics range from General Toxicology, to Genetic Toxicology, Human Clinical Toxicology, Histopathology, Clinical Pathology, Metabolism and Toxicokinetics, Risk Assessment, and more. New to this edition: Completely rewritten chapters covering immunotoxicology, endocrine toxicology, and reproductive and developmental toxicology, providing a fresh perspective on these topics Addition of new chapters on Chemical Toxicology, Pharmaceutical Toxicology, Juvenile Toxicology, and Safety Pharmacology Updated information dealing with Inhalation Toxicology, Neurotoxicology, and Regulatory Toxicology, which has been consolidated into single chapters for each specialty A separate glossary with toxicological terms presented both alphabetically and by toxicological subspecialty For nearly 20 years, this handbook has remained the only reference book of its kind, designed to facilitate easy access to information related to the various toxicology specialties. This updated edition of a popular reference book reflects current practices and the state of the science of toxicology.

Handbook Of Ecotoxicology

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Author : David J. Hoffman
language : en
Publisher: CRC Press
Release Date : 2002-11-13

Handbook Of Ecotoxicology written by David J. Hoffman and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-11-13 with Science categories.

Completely revised and updated with 18 new chapters, this second edition includes contributions from over 75 international experts. Also, a Technical Review Board reviewed all manuscripts for accuracy and currency. Focusing on toxic substance and how they affect the ecosystems worldwide, the book presents methods for quantifying and measuring ecotoxicological effects in the field and in the lab, as well as methods for estimating, predicting, and modeling in ecotoxicology studies. This is the definitive reference for students, researchers, consultants, and other professionals in the environmental sciences, toxicology, chemistry, biology, and ecology - in academia, industry, and government.

Handbook Of Toxicology Of Chemical Warfare Agents

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Author : Ramesh C Gupta
language : en
Publisher: Academic Press
Release Date : 2009-04-02

Handbook Of Toxicology Of Chemical Warfare Agents written by Ramesh C Gupta and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-04-02 with Medical categories.

This groundbreaking book covers every aspect of deadly toxic chemicals used as weapons of mass destruction and employed in conflicts, warfare and terrorism. Including findings from experimental as well as clinical studies, this one-of-a-kind handbook is prepared in a very user- friendly format that can easily be followed by students, teachers and researchers, as well as lay people. Stand-alone chapters on individual chemicals and major topics allow the reader to easily access required information without searching through the entire book.This is the first book that offers in-depth coverage of individual toxicants, target organ toxicity, major incidents, toxic effects in humans, animals and wildlife, biosensors, biomarkers, on-site and laboratory analytical methods, decontamination and detoxification procedures, prophylactic, therapeutic and countermeasures, and the role of homeland security. - Presents a comprehensive look at all aspects of chemical warfare toxicology in one reference work. This saves researchers time in quickly accessing the very latest definitive details on toxicity of specific agents used in chemical warfare as opposed to searching through thousands of journal articles. Will include the most agent-specific information on the market - Includes detailed coverage of the most exhaustive list of agents possibly used as chemical warfare agents in one source. Section 4: Agents That Can Be Used as Weapons of Mass Destruction ? 25 chapters long. Other books on the market only include a sample selection of specific agents. Offering all possible agents detailed under one cover makes this appealing to a wider audience and saves researchers time - The Forward will be written by Dr. Tetsuo Satoh, Chiba University, Japan. He is one of the most respected, recognizable authorities on chemical warfare agents which will set the authoritative tone for the book - Covers risk to humans, animals and the environment equally. Researchers involved in assessing the risks involved with a possible chemical warfare attack and those who are developing response plans to such attacks must look at not only the risks to human health but to our wildlife and environment as well. The holistic approach taken in this book ensures that the researchers have ready access to the details no matter which aspect of the effects of CWA's they might be concerned with

Handbook On The Toxicology Of Metals Specific Metals

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Author : Lars Friberg
language : en
Publisher: Elsevier Science & Technology
Release Date : 1986

Handbook On The Toxicology Of Metals Specific Metals written by Lars Friberg and has been published by Elsevier Science & Technology this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986 with Medical categories.

Chapters on specific metals include physical and chemical properties, methods and problems of analysis, production and uses, environmental levels and exposures, metabolism, levels in tissues and biological fluids, effects and dose-response relationships, carcinogenicity, mutagenicity, teratogenicity and preventative measures, diagnosis, treatment and prognosis.

Hayes Handbook Of Pesticide Toxicology

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Author :
language : en
Publisher: Academic Press
Release Date : 2010-02-15

Hayes Handbook Of Pesticide Toxicology written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-02-15 with Medical categories.

The Handbook of Pesticide Toxicology is a comprehensive, two-volume reference guide to the properties, effects, and regulation of pesticides that provides the latest and most complete information to researchers investigating the environmental, agricultural, veterinary, and human-health impacts of pesticide use. Written by international experts from academia, government, and the private sector, the Handbook of Pesticide Toxicology is an in-depth examination of critical issues related to the need for, use of, and nature of chemicals used in modern pest management. This updated 3e carries on the book's tradition of serving as the definitive reference on pesticide toxicology and recognizes the seminal contribution of Wayland J. Hayes, Jr., co-Editor of the first edition. - Presents a comprehensive look at all aspects of pesticide toxicology in one reference work. - Clear exposition of hazard identification and dose response relationships in each chapter featuring pesticide agents and actions - All major classes of pesticide considered - Different routes of exposure critically evaluated

Information Resources In Toxicology

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Author : P.J. Bert Hakkinen
language : en
Publisher: Academic Press
Release Date : 2009-08-19

Information Resources In Toxicology written by P.J. Bert Hakkinen and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-08-19 with Science categories.

This latest version of Information Resources in Toxicology (IRT) continues a tradition established in 1982 with the publication of the first edition in presenting an extensive itemization, review, and commentary on the information infrastructure of the field. This book is a unique wide-ranging, international, annotated bibliography and compendium of major resources in toxicology and allied fields such as environmental and occupational health, chemical safety, and risk assessment. Thoroughly updated, the current edition analyzes technological changes and is rife with online tools and links to Web sites. IRT-IV is highly structured, providing easy access to its information. Among the "hot topics covered are Disaster Preparedness and Management, Nanotechnology, Omics, the Precautionary Principle, Risk Assessment, and Biological, Chemical and Radioactive Terrorism and Warfare are among the designated. - International in scope, with contributions from over 30 countries - Numerous key references and relevant Web links - Concise narratives about toxicologic sub-disciplines - Valuable appendices such as the IUPAC Glossary of Terms in Toxicology - Authored by experts in their respective sub-disciplines within toxicology