Transdermal Drug Delivery Systems
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Transdermal Drug Delivery Systems
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Author : Jonathan Hadgraft
language : en
Publisher: CRC Press
Release Date : 2002-10-29
Transdermal Drug Delivery Systems written by Jonathan Hadgraft and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-10-29 with Medical categories.
Presents authoritative state-of-the-art discussions of the key issues pertinent to transdermal drug delivery, examining those topics necessary to enable a critical evaluation of a drug candidate's potential to be delivered across the skin; from physical chemistry and assessment of drug permeability to available enhancement technolgies, to regulator
Topical And Transdermal Drug Delivery Systems
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Author : Nayan A. Gujarathi
language : en
Publisher: CRC Press
Release Date : 2023-02-06
Topical And Transdermal Drug Delivery Systems written by Nayan A. Gujarathi and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-02-06 with Medical categories.
Topical and transdermal drug delivery systems (TDDs) have several advantages over traditional drug delivery methods, as they can be less invasive, more sanitary, more cost-effective, and may result in better patient compliance. TDDs play a significant role in therapeutics with a variety of preparations and approaches designed by expert formulation scientists. This volume integrates a wide variety of case studies, research, and theories to reveal their diversity and capture the novel approaches of transdermal and topical drug delivery employed by developers and content experts in the field. It provides an abundance of important information and state-of-the-art research on topical and transdermal drug delivery systems and addresses the basics of drug delivery systems, strategies to enhance permeation across membranes, and formulation and evaluation of diverse dosage forms. The volume presents an evaluation of the pros and cons of conventional drug delivery systems against TDDs and discusses the nuances of micro- and nano-systems in TDDs. The extraordinary packages of nano systems (vesicular systems, polymeric nanoparticles, nanoemulsion and dendrimers) are broadly discussed, and their applications are reviewed through a transdermal route. The book looks at TDDs and the main nanoparticles used in skin diseases and lesions of the aging, such as psoriasis, vitiligo, cancer, lesions of the aging and others. Chapters also discuss polymeric micelles in topical and transdermal delivery; microneedles; emulsion, nanoemulsion and microemulsion; TDDs in pulmonary drug delivery systems; nanoencapsulated nasal drug delivery systems; skin sensitivity and irritation testing for transposing transdermal drug delivery systems; and regulatory aspects of drug development for dermal products. Topical and Transdermal Drug Delivery Systems: Applications and Prospects will be a valuable resource for pharmaceutical scientists and researchers, industry professionals, and academicians and students of the pharmaceutical and biomedical sciences.
Novel Delivery Systems For Transdermal And Intradermal Drug Delivery
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Author : Ryan F. Donnelly
language : en
Publisher: John Wiley & Sons
Release Date : 2015-09-21
Novel Delivery Systems For Transdermal And Intradermal Drug Delivery written by Ryan F. Donnelly and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-09-21 with Science categories.
This research book covers the major aspects relating to the use of novel delivery systems in enhancing both transdermal and intradermal drug delivery. It provides a review of transdermal and intradermal drug delivery, including the history of the field and the various methods employed to produce delivery systems from different materials such as device design, construction and evaluation, so as to provide a sound background to the use of novel systems in enhanced delivery applications. Furthermore, it presents in-depth analyses of recent developments in this exponentially growing field, with a focus on microneedle arrays, needle-free injections, nanoparticulate systems and peptide-carrier-type systems. It also covers conventional physical enhancement strategies, such as tape-stripping, sonophoresis, iontophoresis, electroporation and thermal/suction/laser ablation Discussions about the penetration of the stratum corneum by the various novel strategies highlight the importance of the application method. Comprehensive and critical reviews of transdermal and intradermal delivery research using such systems focus on the outcomes of in vivoanimal and human studies. The book includes laboratory, clinical and commercial case studies featuring safety and patient acceptability studies carried out to date, and depicts a growing area for use of these novel systems is in intradermal vaccine delivery. The final chapters review recent patents in this field and describe the work ongoing in industry.
Topical And Transdermal Drug Delivery
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Author : Heather A. E. Benson
language : en
Publisher: John Wiley & Sons
Release Date : 2012-02-03
Topical And Transdermal Drug Delivery written by Heather A. E. Benson and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-02-03 with Medical categories.
Practical drug development approaches presented by leading experts Designed to support the development of new, effective therapeutics, Topical and Transdermal Drug Delivery: Principles and Practice explains the principles underlying the field and then demonstrates how these principles are put into practice in the design and development of new drug products. Drawing together and reviewing the latest research findings, the book focuses on practical, tested, and proven approaches that are backed by industry case studies and the authors' firsthand experience. Moreover, the book emphasizes the mechanistic information that is essential for successful drug product development. Topical and Transdermal Drug Delivery: Principles and Practice is divided into two parts: Part One, Current Science, Skin Permeation, and Enhancement Approaches, offers readers a fundamental understanding of the underlying science in the field. It describes the principles and techniques needed to successfully perform experimental approaches, covering such issues as skin permeation, enhancement, and assessment. Part Two, Topical and Transdermal Product Development, guides readers through the complete product development process from concept to approval, offering practical tips and cautions from experts in the field. This part also discusses regulations that are specific to the development of dermal drug products. The final chapter explores current and future trends, forecasting new development techniques and therapeutics. Throughout the book, the authors clearly set forth the basic science and experimental procedures, making it possible for researchers to design their own experimental approaches and accurately interpret their results. With contributions from experienced drug researchers, this text is highly recommended for all researchers involved in topical and transdermal product development who need to know both the state of the science and the standards of practice.
Mems Based Transdermal Drug Delivery
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Author : Richa Mishra
language : en
Publisher: CRC Press
Release Date : 2023-12-11
Mems Based Transdermal Drug Delivery written by Richa Mishra and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-12-11 with Technology & Engineering categories.
This book introduces transdermal drug delivery and the developments that have taken place in various transdermal drug delivery techniques including the system-level design approach of a novel miniaturized medical device to offer precise and painless drug delivery via a skin-based transdermal route. It discusses the microelectromechanical systems (MEMS)-based fabrication technique and the design, fabrication and characterization of different MEMS-based components like microneedles and micropumps. It further includes a MEMS-based component micropump with design, analysis, fabrication and characterization of the transdermal drug delivery device and challenges encountered in the design improvements. Features: Summarizes transdermal drug delivery systems especially with a focus on MEMS and microneedles, including theoretical concepts Emphasizes system integration by describing simulation and design techniques as well as experimental fabrication Discusses system-level integration for miniaturized therapeutic devices Includes working simulation models covering microneedles and micropump analysis Explores future direction in development of pertinent devices. The book is aimed at researchers, professionals, and graduate students in biomedical engineering, microelectronics, micro-electro-mechanical-systems, and drug delivery.
Transdermal Drug Delivery
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Author : Jonathan Hadgraft
language : en
Publisher:
Release Date : 1989
Transdermal Drug Delivery written by Jonathan Hadgraft and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989 with Medical categories.
Handbook Of Non Invasive Drug Delivery Systems
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Author : Vitthal S. Kulkarni
language : en
Publisher: Elsevier
Release Date : 2009-12-31
Handbook Of Non Invasive Drug Delivery Systems written by Vitthal S. Kulkarni and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-12-31 with Medical categories.
With the improvements in formulation science and certain transdermal delivery technologies, the non-invasive mode of drug delivery is now ready to compete with traditional methods of oral and injectible routes of drug delivery. The Handbook of Non-Invasive Drug Delivery Systems encompasses the broad field of non-invasive drug delivery systems that include drug delivery via topical, transdermal-passive, transdermal-active (device- aided enhanced penetration), trans-mucosal membrane, trans-ocular membrane as well as delivery via alveolar membrane from inhaled medication. Patient compliance has been found to be much higher when administrated by non-invasive routes and therefore they are considered to be a preferred mode of drug delivery. The book includes both science and technological aspects of new drug delivery systems. Its unique focus is that it is on new drug delivery systems that are considered to be "non-invasive". Other unique features include a chapter on Regulatory Aspects of non-invasive systems and one on FDA guidance for topical nano-drug delivery. Two chapters covering market trends and perspectives, as well as providing guidance to those marketing such systems are also included.
Transdermal Drug Delivery
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Author : Kevin Ita
language : en
Publisher: Academic Press
Release Date : 2020-06-12
Transdermal Drug Delivery written by Kevin Ita and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-12 with Business & Economics categories.
Transdermal Drug Delivery: Concepts and Application provides comprehensive background knowledge and documents the most recent advances made in the field of transdermal drug delivery. It provides comprehensive and updated information regarding most technologies and formulation strategies used for transdermal drug delivery. There has been recent growth in the number of research articles, reviews, and other types of publications in the field of transdermal drug delivery. Research in this area is active both in the academic and industry settings. Ironically, only about 40 transdermal products with distinct active pharmaceutical ingredients are in the market indicating that more needs to be done to chronicle recent advances made in this area and to elucidate the mechanisms involved. This book will be helpful to researchers in the pharmaceutical and biotechnological industries as well as academics and graduate students working in the field of transdermal drug delivery and professionals working in the field of regulatory affairs focusing on topical and transdermal drug delivery systems. Researchers in the cosmetic and cosmeceutical industries, as well as those in chemical and biological engineering, will also find this book useful. Captures the most recent advancements and challenges in the field of transdermal drug delivery Covers both passive and active transdermal drug delivery strategies Explores a selection of state-of-the-art transdermal drug delivery systems
Novel Delivery Systems For Transdermal And Intradermal Drug Delivery
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Author : Ryan F. Donnelly
language : en
Publisher: Wiley
Release Date : 2015-08-18
Novel Delivery Systems For Transdermal And Intradermal Drug Delivery written by Ryan F. Donnelly and has been published by Wiley this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-08-18 with Science categories.
Transdermal And Topical Drug Delivery Systems
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Author : Tapash K. Ghosh
language : en
Publisher: CRC Press
Release Date : 1997-06-30
Transdermal And Topical Drug Delivery Systems written by Tapash K. Ghosh and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-06-30 with Medical categories.
Advances in the pharmaceutical and cosmetic sciences have propelled the development of transdermal and topical therapeutic systems into a technologically revolutionary phase. This book offers an authoritative guide to the development of delivery systems. Discussions by research and industry experts include methods for clinical assessment, percutaneous permeation enhancers, and formulation approaches to topical drug delivery. It also addresses IND, ANDA, NDA, and PLA filings for transdermal products with the FDA. The book contains practical information, step-by-step guidance, numerous references, and a complete index to help readers quickly locate the information they need. Features