Transition States Of Biochemical Processes
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Transition States Of Biochemical Processes
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Author : R. Gandour
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29
Transition States Of Biochemical Processes written by R. Gandour and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Science categories.
The transItIOn-state theory has been, from the point of its inception, the most influential principle in the development of our knowledge of reaction mechanisms in solution. It is natural that as the field of biochemical dynamics has achieved new levels of refinement its students have increasingly adopted the concepts and methods of transition-state theory. Indeed, every dynamical problem of biochemistry finds its most elegant and economical statement in the terms of this theory. Enzyme catalytic power, for example, derives from the interaction of enzyme and substrate structures in the transition state, so that an understanding of this power must grow from a knowledge of these structures and interactions. Similarly, transition-state interactions, and the way in which they change as protein structure is altered, constitute the pivotal feature upon which molecular evolution must turn. The complete, coupled dynamical system of the organism, incorporating the transport of matter and energy as well as local chemical processes, will eventually have to yield to a description of its component transition-state structures and their energetic response characteristics, even if the form of the description goes beyond present-day transition-state theory. Finally, the importance of biochemical effectors in medicine and agriculture carries the subject into the world of practical affairs, in the use of transition-state information for the construction of ultra potent biological agents.
Rational Approaches To Structure Activity And Ecotoxicology Of Agrochemicals
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Author : Wilfried Draber
language : en
Publisher: CRC Press
Release Date : 2024-12-11
Rational Approaches To Structure Activity And Ecotoxicology Of Agrochemicals written by Wilfried Draber and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-12-11 with Technology & Engineering categories.
This book presents discussions of the most important aspects in the development of agrochemicals. The book covers such broad areas as structure activity and ecotoxicological analyses in comprehensive reviews for general methods and chronicles for individual examples. Topics in structure-activity relationships include how to combine submolecular structures of pharmacological interests and modify them according to chemorational models with computer-aided procedures such as the traditional Hansch-type QSAR, the sequential, simplex optimization, and molecular modeling. Topics in the ecotoxicology of organo phosphorus compounds are discussed in terms of the quantitative structure-toxicity relationship (QSTR). Chronicles of molecular orbital methodology in predicting environmental fates of agrochemicals are also provided. This volume will be invaluable for researchers in the agrochemical and pharmaceutical industries.
Plant Growth And Biochemical Processes
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Author : Mr. Rohit Manglik
language : en
Publisher: EduGorilla Publication
Release Date : 2024-04-24
Plant Growth And Biochemical Processes written by Mr. Rohit Manglik and has been published by EduGorilla Publication this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-04-24 with Science categories.
Studies plant growth, photosynthesis, and biochemical pathways. Covers hormonal regulation and environmental impacts on plant development.
Handbook Of Biochemical Kinetics
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Author : Daniel L. Purich
language : en
Publisher: Elsevier
Release Date : 1999-10-26
Handbook Of Biochemical Kinetics written by Daniel L. Purich and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-10-26 with Science categories.
Biochemical kinetics refers to the rate at which a reaction takes place. Kinetic mechanisms have played a major role in defining the metabolic pathways, the mechanistic action of enzymes, and even the processing of genetic material. The Handbook of Biochemical Kinetics provides the "underlying scaffolding" of logic for kinetic approaches to distinguish rival models or mechanisms. The handbook also comments on techniques and their likely limitations and pitfalls, as well as derivations of fundamental rate equations that characterize biochemical processes.Key Features* Over 750 pages devoted to theory and techniques for studying enzymic and metabolic processes* Over 1,500 definitions of kinetic and mechanistic terminology, with key references* Practical advice on experimental design of kinetic experiments* Extended step-by-step methods for deriving rate equations* Over 1,000 enzymes, complete with EC numbers, reactions catalyzed, and references to reviews and/or assay methods* Over 5,000 selected references to kinetic methods appearing in the Methods in Enzymology series* 72-page Wordfinder that allows the reader to search by keywords* Summaries of mechanistic studies on key enzymes and protein systems* Over 250 diagrams, figures, tables, and structures
Kinetics Of Enzyme Action
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Author : Ross L. Stein
language : en
Publisher: John Wiley & Sons
Release Date : 2011-08-08
Kinetics Of Enzyme Action written by Ross L. Stein and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-08-08 with Science categories.
Few scientists have the knowledge to perform the studies that are necessary to discover and characterize enzyme inhibitors, despite the vested interest the pharmaceutical industry has in this field. Beginning with the most basic principles pertaining to simple, one-substrate enzyme reactions and their inhibitors, and progressing to a thorough treatment of two-substrate enzymes, Kinetics of Enzyme Action: Essential Principles for Drug Hunters provides biochemists, medicinal chemists, and pharmaceutical scientists with numerous case study examples to outline the tools and techniques necessary to perform, understand, and interpret detailed kinetic studies for drug discovery.
Advances In Physical Organic Chemistry
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Author : Ian Williams
language : en
Publisher: Academic Press
Release Date : 2019-10-25
Advances In Physical Organic Chemistry written by Ian Williams and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-10-25 with Science categories.
Advances in Physical Organic Chemistry, Volume 53, presents the latest reviews of recent work in physical organic chemistry. It provides a valuable source of information that is ideal not only for physical organic chemists applying their expertise to both novel and traditional problems, but also for non-specialists across diverse areas who identify a physical organic component in their approach to research. Its hallmark is a quantitative, molecular level understanding of phenomena across a diverse range of disciplines. Chapters in this updated release include Theoretical models for activation and reaction energies in chemical reactions, Chiral induction in asymmetric dual catalysis, and The transition state. - Reviews the application of quantitative and mathematical methods to help readers understand chemical problems - Provides the chemical community with authoritative and critical assessments of the many aspects of physical organic chemistry - Covers organic, organometallic, bioorganic, enzymes and materials topics - Presents the only regularly published resource for reviews in physical organic chemistry - Written by authoritative experts who cover a wide range of topics that require a quantitative, molecular-level understanding of phenomena across a diverse range of disciplines
Physiology And Maintenance Volume Ii
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Author : Osmo Otto Paivio Hanninen
language : en
Publisher: EOLSS Publications
Release Date : 2009-09-23
Physiology And Maintenance Volume Ii written by Osmo Otto Paivio Hanninen and has been published by EOLSS Publications this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-09-23 with categories.
Physiology and Maintenance is a component of Encyclopedia of Biological, Physiological and Health Sciences in the global Encyclopedia of Life Support Systems (EOLSS), which is an integrated compendium of twenty one Encyclopedias. The Theme on Physiology and Maintenance with contributions from distinguished experts in the field, discusses the functions of our body and their regulations which are some of the most fascinating areas of science. The content of the theme is organized with state-of-the-art presentations covering the following aspects of the subject: General Physiology; Enzymes: The Biological Catalysts of Life; Nutrition and Digestion; Renal Excretion; Endocrinology; Respiration; Blood Circulation: Its Dynamics And Physiological Control; Locomotion in Sedentary Societies; Neurophysiology; Plant Physiology and Environment : A Synopsis, which are then expanded into multiple subtopics, each as a chapter. These five volumes are aimed at the following five major target audiences: University and College students Educators, Professional practitioners, Research personnel and Policy analysts, managers, and decision makers and NGOs.
Biochemistry
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Author : Terry Brown
language : en
Publisher: Scion Publishing Ltd
Release Date : 2016-09-22
Biochemistry written by Terry Brown and has been published by Scion Publishing Ltd this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-22 with Science categories.
Biochemistry is a major new textbook designed and created specifically for briefer courses in the subject. Written by Prof. Terry Brown of the University of Manchester (author of Genomes and Gene Cloning), the book provides the necessary detail and rigour expected for these courses, but without the extraneous material found in the larger textbooks. With an increasing number of students taking a short course in biochemistry there is a growing need for a book that covers the subject concisely and succinctly. Biochemistry has been designed from the outset for these shorter courses; it is not a cut-down version of one of the larger books that dominate the market. Although it is shorter, there is no compromise in content, style and coverage. The book is attractively designed in full colour throughout with all the pedagogical features expected in a major textbook. It covers what students should be expected to know and is written in the clear and accurate writing style for which Terry Brown is widely lauded. With its competitive price and resources for adopting lecturers (all of the illustrations and diagrams from the book, and answers to the end of chapter questions), Biochemistry will become the textbook of choice for any brief biochemistry course. Confirmed Adoptions Biochemistry is already the required text at the following institutions: Becker College, USA Bishop Burton College, UK Bournemouth University, UK Charles R. Drew University of Medicine and Science, USA Charleston Southern University, USA Colorado State University - Pueblo, USA Idaho State University, USA Liverpool John Moores University, UK Montclair State University, USA Newcastle University, UK Rivier University, USA Southeast Missouri State University, USA Staffordshire University, UK Stephen F Austin State University, USA Texas Christian University, USA The University of Texas at Austin, USA Umeå University, Sweden University of Aberdeen, UK University of Bradford, UK University of Bedfordshire, UK University of Brighton, UK University of the Incarnate Word, USA University of Kansas, USA University of Miami Miller School of Medicine, USA University of Nottingham, UK University of Roehampton, UK University of Salford, UK University of the West of England, UK University of Tulsa, USA Valley City State University, USA Yale University School of Medicine, USA
Computational Approaches For Studying Enzyme Mechanism Part A
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Author :
language : en
Publisher: Academic Press
Release Date : 2016-08-04
Computational Approaches For Studying Enzyme Mechanism Part A written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-04 with Science categories.
Computational Approaches for Studying Enzyme Mechanism Part A, is the first of two volumes in the Methods in Enzymology series, focusses on computational approaches for studying enzyme mechanism. The serial achieves the critically acclaimed gold standard of laboratory practices and remains one of the most highly respected publications in the molecular biosciences. Each volume is eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with over 550 volumes, the series remains a prominent and essential publication for researchers in all fields of life sciences and biotechnology, including biochemistry, chemical biology, microbiology, synthetic biology, cancer research, and genetics to name a few. - Focuses on computational approaches for studying enzyme mechanism - Continues the legacy of this premier serial with quality chapters authored by leaders in the field - Covers research methods in intermediate filament associated proteins, and contains sections on such topics as lamin-associated proteins, intermediate filament-associated proteins and plakin, and other cytoskeletal cross-linkers
Biochemistry
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Author : David E. Metzler
language : en
Publisher: Academic Press
Release Date : 2001-03-23
Biochemistry written by David E. Metzler and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-03-23 with Medical categories.
Biochemistry: The Chemical Reactions of Living Cells is a well-integrated, up-to-date reference for basic biochemistry, associated chemistry, and underlying biological phenomena. Biochemistry is a comprehensive account of the chemical basis of life, describing the amazingly complex structures of the compounds that make up cells, the forces that hold them together, and the chemical reactions that allow for recognition, signaling, and movement. This book contains information on the human body, its genome, and the action of muscles, eyes, and the brain. It also features: thousands of literature references that provide introduction to current research as well as historical background; twice the number of chapters of the first edition; and each chapter contains boxes of information on topics of general interest. -- Publisher description.