Translational Approaches To Unravelling Non Motor Symptoms Of Parkinson S Disease


Translational Approaches To Unravelling Non Motor Symptoms Of Parkinson S Disease
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Translational Approaches To Unravelling Non Motor Symptoms Of Parkinson S Disease


Translational Approaches To Unravelling Non Motor Symptoms Of Parkinson S Disease
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Author :
language : en
Publisher: Elsevier
Release Date : 2024-02

Translational Approaches To Unravelling Non Motor Symptoms Of Parkinson S Disease written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-02 with Medical categories.


Translational Approaches to Non-Motor Symptoms of Neurodegenerative Diseases, Volume 173 in the International Review on Neurobiology series, highlights new advances in the field with this new volume presenting interesting chapters on topics such as A general clinical overview of the non-motor symptoms, Stress/fatigue/cognitive decline Sleep/autonomic failure, A general clinical overview of the non-motor symptoms - psychiatric symptoms, Psychosis, Cognitive Decline, Non-clinical Aspect of non-motor symptoms: Animal Models, Assessment and treatment of cognitive decline in rodent and primate models, Pain in PD models, Affective disorders in PD models, Sleep and circadian dysregulation and EEG disruption in rodent models, and much more.



Translational Approaches To Unravelling Non Motor Symptoms Of Parkinson S Disease


Translational Approaches To Unravelling Non Motor Symptoms Of Parkinson S Disease
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Author :
language : en
Publisher: Elsevier
Release Date : 2024-02-09

Translational Approaches To Unravelling Non Motor Symptoms Of Parkinson S Disease written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-02-09 with Science categories.


Translational Approaches to Non-Motor Symptoms of Neurodegenerative Diseases, Volume 173 in the International Review on Neurobiology series, highlights new advances in the field with this new volume presenting interesting chapters on topics such as A general clinical overview of the non-motor symptoms, Stress/fatigue/cognitive decline Sleep/autonomic failure, A general clinical overview of the non-motor symptoms – psychiatric symptoms, Psychosis, Cognitive Decline, Non-clinical Aspect of non-motor symptoms: Animal Models, Assessment and treatment of cognitive decline in rodent and primate models, Pain in PD models, Affective disorders in PD models, Sleep and circadian dysregulation and EEG disruption in rodent models, and much more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in International Review on Neurobiology serials Updated release includes the latest information on Translational Approaches to Non-Motor Symptoms of Neurodegenerative Diseases



Prodromal Parkinson S Disease


Prodromal Parkinson S Disease
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Author : David Crosiers
language : en
Publisher: Frontiers Media SA
Release Date : 2021-02-17

Prodromal Parkinson S Disease written by David Crosiers and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-02-17 with Medical categories.




Non Motor Symptoms Of Parkinson S Disease


Non Motor Symptoms Of Parkinson S Disease
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Author : K. Ray Chaudhuri
language : en
Publisher: Oxford University Press, USA
Release Date : 2014

Non Motor Symptoms Of Parkinson S Disease written by K. Ray Chaudhuri and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with Medical categories.


Patients with Parkinson's disease (PD) are known to suffer from motor symptoms of the disease, but they also experience non-motor symptoms (NMS) that are often present before diagnosis or that inevitably emerge with disease progression. The motor symptoms of Parkinson's disease have been extensively researched, and effective clinical tools for their assessment and treatment have been developed and are readily available. In contrast, researchers have only recently begun to focus on the NMS of Parkinson's Disease, which are poorly recognized and inadequately treated by clinicians. The NMS of PD have a significant impact on patient quality of life and mortality and include neuropsychiatric, sleep-related, autonomic, gastrointestinal, and sensory symptoms. While some NMS can be improved with currently available treatments, others may be more refractory and will require research into novel (non-dopaminergic) drug therapies for the future. Edited by members of the UK Parkinson's Disease Non-Motor Group (PD-NMG) and with contributions from international experts, this new edition summarizes the current understanding of NMS symptoms in Parkinson's disease and points the way towards future research.



Human And Animal Models For Translational Research On Neurodegeneration Challenges And Opportunities From South America


Human And Animal Models For Translational Research On Neurodegeneration Challenges And Opportunities From South America
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Author : Agustín Ibáñez
language : en
Publisher: Frontiers Media SA
Release Date : 2018-06-21

Human And Animal Models For Translational Research On Neurodegeneration Challenges And Opportunities From South America written by Agustín Ibáñez and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-21 with categories.


Neurodegenerative diseases are the most frequent cause of dementia, representing a burden for public health systems (especially in middle and middle-high income countries). Although most research on this issue is concentrated in first-world centers, growing efforts in South America are affording important breakthroughs. This emerging agenda poses new challenges for the region but also new opportunities for the field. This book aims to integrate the community of experts across the globe and the region, and to establish new challenges and developments for future investigation. We present research focused on neurodegenerative research in South America. We introduce studies assessing the interplay among genetic, neural, and behavioral dimensions of these diseases, as well as articles on vulnerability factors, comparisons of findings from various countries, and works promoting multicenter and collaborative networking. More generally, our book covers a broad scope of human-research approaches (behavioral assessment, neuroimaging, electromagnetic techniques, brain connectivity, peripheral measures), animal methodologies (genetics, epigenetics, proteomics, metabolomics, other molecular biology tools), species (all human and non-human animals, sporadic, and genetic versions), and article types (original research, review, and opinion papers). Through this wide-ranging proposal, we hope to introduce a fresh approach to the challenges and opportunities of research on neurodegeneration in South America.



Etiology Of Parkinson S Disease


Etiology Of Parkinson S Disease
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Author : Jonas H. Ellenberg
language : en
Publisher: CRC Press
Release Date : 1995-03-01

Etiology Of Parkinson S Disease written by Jonas H. Ellenberg and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-03-01 with Medical categories.


This comprehensive reference provides a detailed overview of current concepts regarding the cause of Parkinson's disease-emphasizing the issues involved in the design, implementation, and analysis of epidemiological studies of parkinsonism.



Autonomic Dysfunction In Parkinson S Disease


Autonomic Dysfunction In Parkinson S Disease
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Author : Cristian Falup-Pecurariu
language : en
Publisher: Academic Press
Release Date : 2021-09-28

Autonomic Dysfunction In Parkinson S Disease written by Cristian Falup-Pecurariu and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-28 with Technology & Engineering categories.


Autonomic dysfunction is one of the most prevalent non-motor symptoms that occurs in Parkinson’s disease. Autonomic Dysfunction in Parkinson's Disease provides up to date information on this important topic, which affects quality of life of these patients. This include a large number of domains: orthostatic hypotension, excessive sweating, dry eyes, constipation, weight loss, increased sensitivity to heat and cold, sexual dysfunction. Provides comprehensive reviews on different topics of autonomic dysfunction in Parkinson’s disease Each chapter covers a specific autonomic symptom: classification, assessment, treatment Presents the newest information on each autonomic symptom in Parkinson’s disease



Translational Advances In Alzheimer S Parkinson S And Other Neurodegenerative Dementias


Translational Advances In Alzheimer S Parkinson S And Other Neurodegenerative Dementias
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Author : Jiehui Jiang
language : en
Publisher: Frontiers Media SA
Release Date : 2022-07-05

Translational Advances In Alzheimer S Parkinson S And Other Neurodegenerative Dementias written by Jiehui Jiang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-07-05 with Science categories.




Conn S Translational Neuroscience


Conn S Translational Neuroscience
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Author : P. Michael Conn
language : en
Publisher: Academic Press
Release Date : 2016-09-28

Conn S Translational Neuroscience written by P. Michael Conn and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-28 with Medical categories.


Conn’s Translational Neuroscience provides a comprehensive overview reflecting the depth and breadth of the field of translational neuroscience, with input from a distinguished panel of basic and clinical investigators. Progress has continued in understanding the brain at the molecular, anatomic, and physiological levels in the years following the 'Decade of the Brain,' with the results providing insight into the underlying basis of many neurological disease processes. This book alternates scientific and clinical chapters that explain the basic science underlying neurological processes and then relates that science to the understanding of neurological disorders and their treatment. Chapters cover disorders of the spinal cord, neuronal migration, the autonomic nervous system, the limbic system, ocular motility, and the basal ganglia, as well as demyelinating disorders, stroke, dementia and abnormalities of cognition, congenital chromosomal and genetic abnormalities, Parkinson's disease, nerve trauma, peripheral neuropathy, aphasias, sleep disorders, and myasthenia gravis. In addition to concise summaries of the most recent biochemical, physiological, anatomical, and behavioral advances, the chapters summarize current findings on neuronal gene expression and protein synthesis at the molecular level. Authoritative and comprehensive, Conn’s Translational Neuroscience provides a fully up-to-date and readily accessible guide to brain functions at the cellular and molecular level, as well as a clear demonstration of their emerging diagnostic and therapeutic importance. Provides a fully up-to-date and readily accessible guide to brain functions at the cellular and molecular level, while also clearly demonstrating their emerging diagnostic and therapeutic importance Features contributions from leading global basic and clinical investigators in the field Provides a great resource for researchers and practitioners interested in the basic science underlying neurological processes Relates and translates the current science to the understanding of neurological disorders and their treatment



Insights Into Human Neurodegeneration Lessons Learnt From Drosophila


Insights Into Human Neurodegeneration Lessons Learnt From Drosophila
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Author : Mousumi Mutsuddi
language : en
Publisher: Springer Nature
Release Date : 2019-12-05

Insights Into Human Neurodegeneration Lessons Learnt From Drosophila written by Mousumi Mutsuddi and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-12-05 with Medical categories.


This book is aimed at generating an updated reservoir of scientific endeavors undertaken to unravel the complicated yet intriguing topic of neurodegeneration. Scientists from Europe, USA and India who are experts in the field of neurodegenerative diseases have contributed to this book. This book will help readers gain insight into the recent knowledge obtained from Drosophila model, in understanding the molecular mechanisms underlying neurodegenerative disorders and also unravel novel scopes for therapeutic interventions. Different methodologies available to create humanized fly models that faithfully reflects the pathogenicities associated with particular disorders have been described here. It also includes information on the exciting area of neural stem cells. A brief discussion on neurofibrillary tangles, precedes the elaborate description of lessons learnt from Drosophila about Alzheimer's, Parkinson’s, Spinomuscular Atrophy, Huntington’s diseases, RNA expansion disorders and Hereditary Spastic Paraplegia. We have concluded the book with the use of Drosophila for identifying pharmacological therapies for neurodegenerative disorders. The wide range of topics covered here will not only be relevant for beginners who are new to the concept of the extensive utility of Drosophila as a model to study human disorders; but will also be an important contribution to the scientific community, with an insight into the paradigm shift in our understanding of neurodegenerative disorders. Completed with informative tables and communicative illustrations this book will keep the readers glued and intrigued. We have comprehensively anthologized the lessons learnt on neurodegeneration from Drosophila and have thus provided an insight into the multidimensional aspects of pathogenicities of majority of the neurodegenerative disorders.