Translational Biomedical Informatics
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Translational Biomedical Informatics
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Author : Bairong Shen
language : en
Publisher: Springer
Release Date : 2016-10-31
Translational Biomedical Informatics written by Bairong Shen and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-10-31 with Science categories.
This book introduces readers to essential methods and applications in translational biomedical informatics, which include biomedical big data, cloud computing and algorithms for understanding omics data, imaging data, electronic health records and public health data. The storage, retrieval, mining and knowledge discovery of biomedical big data will be among the key challenges for future translational research. The paradigm for precision medicine and healthcare needs to integratively analyze not only the data at the same level – e.g. different omics data at the molecular level – but also data from different levels – the molecular, cellular, tissue, clinical and public health level. This book discusses the following major aspects: the structure of cross-level data; clinical patient information and its shareability; and standardization and privacy. It offers a valuable guide for all biologists, biomedical informaticians and clinicians with an interest in Precision Medicine Informatics.
Translational Bioinformatics In Healthcare And Medicine
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Author :
language : en
Publisher: Academic Press
Release Date : 2021-05-13
Translational Bioinformatics In Healthcare And Medicine written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-05-13 with Medical categories.
Translational Bioinformatics in Healthcare and Medicine offers an overview of main principles of bioinformatics, biological databases, clinical informatics, health informatics, viroinformatics and real-case applications of translational bioinformatics in healthcare. Written by experts from both technology and clinical sides, the content brings together essential knowledge to make the best of recent advancements of the field. The book discusses topics such as next generation sequence analysis, genomics in clinical care, IoT applications, blockchain technology, patient centered interoperability of EHR, health data mining, and translational bioinformatics methods for drug discovery and drug repurposing. In addition, it discusses the role of bioinformatics in cancer research and viroinformatics approaches to counter viral diseases through informatics. This is a valuable resource for bioinformaticians, clinicians, healthcare professionals, graduate students and several members of biomedical field who are interested in learning more about how bioinformatics can impact in their research and practice. - Covers recent advancements in translational bioinformatics and its healthcare applications - Discusses integrative and multidisciplinary approaches to U-healthcare systems development and management - Bridges the gap among various knowledge domains in the field, integrating both technological and clinical knowledge into practical content
Translational Bioinformatics And Its Application
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Author : Dong-Qing Wei
language : en
Publisher: Springer
Release Date : 2018-07-25
Translational Bioinformatics And Its Application written by Dong-Qing Wei and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-07-25 with Science categories.
This book offers a detailed overview of translational bioinformatics together with real-case applications. Translational bioinformatics integrates the areas of basic bioinformatics, clinical informatics, statistical genetics and informatics in order to further our understanding of the molecular basis of diseases. By analyzing voluminous amounts of molecular and clinical data, it also provides clinical information, which can then be applied. Filling the gap between clinic research and informatics, the book is a valuable resource for human geneticists, clinicians, health educators and policy makers, as well as graduate students majoring in biology, biostatistics, and bioinformatics.
Pediatric Biomedical Informatics
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Author : John J. Hutton
language : en
Publisher: Springer
Release Date : 2016-10-08
Pediatric Biomedical Informatics written by John J. Hutton and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-10-08 with Medical categories.
The book describes the core resources in informatics necessary to support biomedical research programs and how these can best be integrated with hospital systems to receive clinical information that is necessary to conduct translational research. The focus is on the authors’ recent practical experiences in establishing an informatics infrastructure in a large research-intensive children’s hospital. This book is intended for translational researchers and informaticians in pediatrics, but can also serve as a guide to all institutions facing the challenges of developing and strengthening informatics support for biomedical research. The first section of the book discusses important technical challenges underlying computer-based pediatric research, while subsequent sections discuss informatics applications that support biobanking and a broad range of research programs. Pediatric Biomedical Informatics provides practical insights into the design, implementation, and utilization of informatics infrastructures to optimize care and research to benefit children.
Translational Bioinformatics And Systems Biology Methods For Personalized Medicine
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Author : Qing Yan
language : en
Publisher: Academic Press
Release Date : 2017-04-18
Translational Bioinformatics And Systems Biology Methods For Personalized Medicine written by Qing Yan and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-04-18 with Science categories.
Translational Bioinformatics and Systems Biology Methods for Personalized Medicine introduces integrative approaches in translational bioinformatics and systems biology to support the practice of personalized, precision, predictive, preventive, and participatory medicine. Through the description of important cutting-edge technologies in bioinformatics and systems biology, readers may gain an essential understanding of state-of-the-art methodologies. The book discusses topics such as the challenges and tasks in translational bioinformatics; pharmacogenomics, systems biology, and personalized medicine; and the applicability of translational bioinformatics for biomarker discovery, epigenomics, and molecular dynamics. It also discusses data integration and mining, immunoinformatics, and neuroinformatics. With broad coverage of both basic scientific and clinical applications, this book is suitable for a wide range of readers who may not be scientists but who are also interested in the practice of personalized medicine. - Introduces integrative approaches in translational bioinformatics and systems biology to support the practice of personalized, precision, predictive, preventive, and participatory medicine - Presents a problem-solving oriented methodology to deal with practical problems in various applications - Covers both basic scientific and clinical applications in order to enhance the collaboration between researchers and clinicians - Brings integrative and multidisciplinary approaches to bridge the gaps among various knowledge domains in the field
Translational Bioinformatics Applications In Healthcare
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Author : Khalid Raza
language : en
Publisher: CRC Press
Release Date : 2021-04-19
Translational Bioinformatics Applications In Healthcare written by Khalid Raza and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-19 with Computers categories.
Translational bioinformatics (TBI) involves development of storage, analytics, and advanced computational methods to harvest knowledge from voluminous biomedical and genomic data into 4P healthcare (proactive, predictive, preventive, and participatory). Translational Bioinformatics Applications in Healthcare offers a detailed overview on concepts of TBI, biological and clinical databases, clinical informatics, and pertinent real-case applications. It further illustrates recent advancements, tools, techniques, and applications of TBI in healthcare, including Internet of Things (IoT) potential, toxin databases, medical image analysis and telemedicine applications, analytics of COVID-19 CT images, viroinformatics and viral diseases, and COVID-19–related research. Covers recent technologies such as Blockchain, IoT, and Big data analytics in bioinformatics Presents the role of translational bioinformatic methods in the field of viroinformatics, as well as in drug development and repurposing Includes translational healthcare and NGS for clinical applications Illustrates translational medicine systems and their applications in better healthcare Explores medical image analysis with focus on CT images and novel coronavirus disease detection Aimed at researchers and graduate students in computational biology, data mining and knowledge discovery, algorithms and complexity, and interdisciplinary fields of studies, including bioinformatics, health-informatics, biostatistics, biomedical engineering, and viroinformatics. Khalid Raza is an Assistant Professor, the Department of Computer Science, Jamia Millia Islamia (Central University), New Delhi. His research interests include translational bioinformatics, computational intelligence methods and its applications in bioinformatics, viroinformatics, and health informatics. Nilanjan Dey is an Associate Professor, the Department of Computer Science and Engineering, JIS University, Kolkata, India. His research interests include medical imaging, machine learning, computer-aided diagnosis, and data mining.
Bioinformatics For Diagnosis Prognosis And Treatment Of Complex Diseases
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Author : Bairong Shen
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-25
Bioinformatics For Diagnosis Prognosis And Treatment Of Complex Diseases written by Bairong Shen and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-25 with Science categories.
The book introduces the bioinformatics tools, databases and strategies for the translational research, focuses on the biomarker discovery based on integrative data analysis and systems biological network reconstruction. With the coming of personal genomics era, the biomedical data will be accumulated fast and then it will become reality for the personalized and accurate diagnosis, prognosis and treatment of complex diseases. The book covers both state of the art of bioinformatics methodologies and the examples for the identification of simple or network biomarkers. In addition, bioinformatics software tools and scripts are provided to the practical application in the study of complex diseases. The present state, the future challenges and perspectives were discussed. The book is written for biologists, biomedical informatics scientists and clinicians, etc. Dr. Bairong Shen is Professor and Director of Center for Systems Biology, Soochow University; he is also Director of Taicang Center for Translational Bioinformatics.
Applied Computational Genomics
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Author : Yin Yao Shugart
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-30
Applied Computational Genomics written by Yin Yao Shugart and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-30 with Medical categories.
"Applied Computational Genomics" focuses on an in-depth review of statistical development and application in the area of human genomics including candidate gene mapping, linkage analysis, population-based, genome-wide association, exon sequencing and whole genome sequencing analysis. The authors are extremely experienced in the area of statistical genomics and will give a detailed introduction of the evolution in the field and critical evaluations of the advantages and disadvantages of the statistical models proposed. They will also share their views on a future shift toward translational biology. The book will be of value to human geneticists, medical doctors, health educators, policy makers, and graduate students majoring in biology, biostatistics, and bioinformatics. Dr. Yin Yao Shugart is investigator in the Intramural Research Program at the National Institute of Mental Health, Bethesda, Maryland USA.
Biomedical Informatics
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Author : Edward H. Shortliffe
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-12-02
Biomedical Informatics written by Edward H. Shortliffe and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-02 with Medical categories.
The practice of modern medicine and biomedical research requires sophisticated information technologies with which to manage patient information, plan diagnostic procedures, interpret laboratory results, and carry out investigations. Biomedical Informatics provides both a conceptual framework and a practical inspiration for this swiftly emerging scientific discipline at the intersection of computer science, decision science, information science, cognitive science, and biomedicine. Now revised and in its third edition, this text meets the growing demand by practitioners, researchers, and students for a comprehensive introduction to key topics in the field. Authored by leaders in medical informatics and extensively tested in their courses, the chapters in this volume constitute an effective textbook for students of medical informatics and its areas of application. The book is also a useful reference work for individual readers needing to understand the role that computers can play in the provision of clinical services and the pursuit of biological questions. The volume is organized so as first to explain basic concepts and then to illustrate them with specific systems and technologies.
Methods In Biomedical Informatics
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Author : Indra Neil Sarkar
language : en
Publisher: Academic Press
Release Date : 2013-09-03
Methods In Biomedical Informatics written by Indra Neil Sarkar and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-09-03 with Computers categories.
Beginning with a survey of fundamental concepts associated with data integration, knowledge representation, and hypothesis generation from heterogeneous data sets, Methods in Biomedical Informatics provides a practical survey of methodologies used in biological, clinical, and public health contexts. These concepts provide the foundation for more advanced topics like information retrieval, natural language processing, Bayesian modeling, and learning classifier systems. The survey of topics then concludes with an exposition of essential methods associated with engineering, personalized medicine, and linking of genomic and clinical data. Within an overall context of the scientific method, Methods in Biomedical Informatics provides a practical coverage of topics that is specifically designed for: (1) domain experts seeking an understanding of biomedical informatics approaches for addressing specific methodological needs; or (2) biomedical informaticians seeking an approachable overview of methodologies that can be used in scenarios germane to biomedical research. - Contributors represent leading biomedical informatics experts: individuals who have demonstrated effective use of biomedical informatics methodologies in the real-world, high-quality biomedical applications - Material is presented as a balance between foundational coverage of core topics in biomedical informatics with practical "in-the-trenches" scenarios. - Contains appendices that function as primers on: (1) Unix; (2) Ruby; (3) Databases; and (4) Web Services.