Translational Control In Biology And Medicine
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Translational Control In Biology And Medicine
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Author : Michael Mathews
language : en
Publisher: CSHL Press
Release Date : 2007
Translational Control In Biology And Medicine written by Michael Mathews and has been published by CSHL Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Medical categories.
Updated and broadened 3rd edition. Since the last edition was published, the structures of the bacterial and eukaryotic ribosomes have been published, adding substantially to our knowledge of the basic mechanisms of translation. Understanding of how translation is regulated, by both protein and RNA regulators, has also advanced considerable. In addition, the current manifesttion of this volume has a significant focus on the role of translational control in human development and disease.
Translation And Its Regulation In Cancer Biology And Medicine
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Author : Armen Parsyan
language : en
Publisher: Springer
Release Date : 2014-10-13
Translation And Its Regulation In Cancer Biology And Medicine written by Armen Parsyan and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10-13 with Medical categories.
This book, for the first time, comprehensively assembles and analyzes a large body of information on the role of the fundamental mechanism of the protein biosynthesis pathway, translation, in cancer biology. It systematically explores the function of the translation machinery and its regulation, including cell signaling, in the development, maintenance and progression of human cancer. The work presented here unveils the tremendous potential and applications of this vast and exciting branch of genetic, biochemical and molecular science in cancer medicine and drug development. Chapters contributed by experts in the field take the reader on a journey that starts with a dissection of the translation machinery and its regulation in norm and cancer. Later chapters characterize etiological and pathogenetic roles that translation plays in specific cancer types. Various aspects of diagnostic, prognostic and therapeutic significance of the translation machinery and its control in cancer are discussed. Readers will discover the importance of the process of translation and its regulatory mechanisms in physiology and cancer biology. The chapters and the numerous illustrations included here were contributed by expert scientists and clinicians from renowned academic and clinical establishments in Canada, the United States of America, the United Kingdom, Italy, France, Belgium, Spain, Germany and Australia. The book conveys information and knowledge that may interest a broad range of students and scholars ranging from basic scientists to clinicians and drug developers seeking to better understand the protein synthesis and its aberrations in cancer biology and cancer medicine.
Translational Control In Health And Disease
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Author :
language : en
Publisher: Academic Press
Release Date : 2009-10-26
Translational Control In Health And Disease written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-10-26 with Medical categories.
Progress in Molecular Biology and Translational Science provides a forum for discussion of new discoveries, approaches, and ideas in molecular biology and translational science. It contains contributions from leaders in their fields and abundant references. This volume focuses on translational control in health and disease. Contributions from leading scholars and industry experts Reference guide for researchers involved in molecular biology and related fields
Translational Control
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Author : Michael B. Mathews
language : en
Publisher:
Release Date : 1986
Translational Control written by Michael B. Mathews and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986 with Science categories.
Translational Biology In Medicine
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Author : M. Montano
language : en
Publisher: Elsevier
Release Date : 2014-12-08
Translational Biology In Medicine written by M. Montano and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-12-08 with Science categories.
The recent emphasis in biomedical research on translational biology and personalized medicine is revolutionizing conceptual and experimental approaches to understanding and improving human health. Translational Biology in Medicine begins with an introduction to experimental model systems for disease, such as cell lines, primary cells, stem cells and animal models for disease, followed by a systematic description of genetic and genomic profiling and biomarker validation currently used in biomedical research. Examples of translation studies that have used these models and methods are presented, including studies in aging, tissue repair and chronic infection, each with an emphasis on how personalized medicine is transforming biomedicine. Bioethical considerations in translational study design and bioethical considerations in biomedical research are then covered, before concluding remarks, and a look towards the future of personalized medicine. Describes cellular and animal model systems used in translational research Discusses the use of blood, genetic and genomic biomarkers for disease Presents translational studies in aging, tissue repair and infectious disease biomedicine
Translational Regulation Of Gene Expression
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Author : J. Ilan
language : en
Publisher: Springer
Release Date : 1988-01-31
Translational Regulation Of Gene Expression written by J. Ilan and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988-01-31 with Medical categories.
Abstracts Of Papers Presented At The 1992 Meeting On Translational Control
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Author :
language : en
Publisher:
Release Date : 1992
Abstracts Of Papers Presented At The 1992 Meeting On Translational Control written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with Genetic regulation categories.
Transcriptional And Translational Regulation Of Stem Cells
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Author : Gary Hime
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-05-22
Transcriptional And Translational Regulation Of Stem Cells written by Gary Hime and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-22 with Medical categories.
This volume describes the latest findings on transcriptional and translational regulation of stem cells. Both transcriptional activators and repressors have been shown to be crucial for the maintenance of the stem cell state. A key element of stem cell maintenance is repression of differentiation factors or developmental genes – achieved transcriptionally, epigenetically by the Polycomb complex, and post-transcriptionally by RNA-binding proteins and microRNAs. This volume takes two approaches to this topic – (1) illustrating the general principles outlined above through a series of different stem cell examples – embryonic, iPS and adult stem cells, and (2) describing several molecular families that have been shown to have roles in regulation of multiple stem cell populations.
Translation Mechanisms
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Author : Jacques Lapointe
language : en
Publisher: Springer Science & Business Media
Release Date : 2003-07-31
Translation Mechanisms written by Jacques Lapointe and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-07-31 with Science categories.
Translation Mechanisms provides investigators and graduate students with overviews of recent developments in the field of protein biosynthesis that are fuelled by the explosive and synergic growth of structural biology, genomics, and bioinformatics. The outstanding progress in our understanding of the structure, dynamics, and evolution of the prokaryotic and eukaryotic translation machinery, as well as applications in medicine and biotechnology, are described in 26 chapters covering recent discoveries on: -the subtleties of tRNA aminoacylation with natural and unnatural amino acids. -the control of mRNA stability, a key step of gene regulation. -ribosome structure and function, in the era of the atomic-crystal resolution of the ribosome. -the regulation of the biosynthesis of the translational machinery components. -the action of a variety of inhibitors of translation and the prospect for clinical studies.
Biology Of The Nmda Receptor
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Author : Antonius M. VanDongen
language : en
Publisher: CRC Press
Release Date : 2008-10-29
Biology Of The Nmda Receptor written by Antonius M. VanDongen and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-10-29 with Medical categories.
The NMDA receptor plays a critical role in the development of the central nervous system and in adult neuroplasticity, learning, and memory. Therefore, it is not surprising that this receptor has been widely studied. However, despite the importance of rhythms for the sustenance of life, this aspect of NMDAR function remains poorly studied. Written