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Translational Control In Health And Disease


Translational Control In Health And Disease
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Translational Control In Health And Disease


Translational Control In Health And Disease
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Author :
language : en
Publisher: Academic Press
Release Date : 2009-10-26

Translational Control In Health And Disease written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-10-26 with Medical categories.


Progress in Molecular Biology and Translational Science provides a forum for discussion of new discoveries, approaches, and ideas in molecular biology and translational science. It contains contributions from leaders in their fields and abundant references. This volume focuses on translational control in health and disease. Contributions from leading scholars and industry experts Reference guide for researchers involved in molecular biology and related fields



Translational Control Of Mrnas In The Brain In Health And Disease


Translational Control Of Mrnas In The Brain In Health And Disease
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Author : Konstanze Simbriger
language : en
Publisher:
Release Date : 2019

Translational Control Of Mrnas In The Brain In Health And Disease written by Konstanze Simbriger and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019 with categories.




Rna Based Regulation In Human Health And Disease


Rna Based Regulation In Human Health And Disease
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Author :
language : en
Publisher: Academic Press
Release Date : 2020-08-19

Rna Based Regulation In Human Health And Disease written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-19 with Medical categories.


RNA-based Regulation in Human Health and Disease offers an in-depth exploration of RNA mediated genome regulation at different hierarchies. Beginning with multitude of canonical and non-canonical RNA populations, especially noncoding RNA in human physiology and evolution, further sections examine the various classes of RNAs (from small to large noncoding and extracellular RNAs), functional categories of RNA regulation (RNA-binding proteins, alternative splicing, RNA editing, antisense transcripts and RNA G-quadruplexes), dynamic aspects of RNA regulation modulating physiological homeostasis (aging), role of RNA beyond humans, tools and technologies for RNA research (wet lab and computational) and future prospects for RNA-based diagnostics and therapeutics. One of the core strengths of the book includes spectrum of disease-specific chapters from experts in the field highlighting RNA-based regulation in metabolic & neurodegenerative disorders, cancer, inflammatory disease, viral and bacterial infections. We hope the book helps researchers, students and clinicians appreciate the role of RNA-based regulation in genome regulation, aiding the development of useful biomarkers for prognosis, diagnosis, and novel RNA-based therapeutics. Comprehensive information of non-canonical RNA-based genome regulation modulating human health and disease Defines RNA classes with special emphasis on unexplored world of noncoding RNA at different hierarchies Disease specific role of RNA - causal, prognostic, diagnostic and therapeutic Features contributions from leading experts in the field



Translational Control Of Gene Expression


Translational Control Of Gene Expression
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Author : Nahum Sonenberg
language : en
Publisher: CSHL Press
Release Date : 2001

Translational Control Of Gene Expression written by Nahum Sonenberg and has been published by CSHL Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with Gene expression categories.


Since the 1996 publication of Translational Control, there has been fresh interest in protein synthesis and recognition of the key role of translation control mechanisms in regulating gene expression. This new monograph updates and expands the scope of the earlier book but it also takes a fresh look at the field. In a new format, the first eight chapters provide broad overviews, while each of the additional twenty-eight has a focus on a research topic of more specific interest. The result is a thoroughly up-to-date account of initiation, elongation, and termination of translation, control mechanisms in development in response to extracellular stimuli, and the effects on the translation machinery of virus infection and disease. This book is essential reading for students entering the field and an invaluable resource for investigators of gene expression and its control.



Post Translational Modifications In Health And Disease


Post Translational Modifications In Health And Disease
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Author : Cecilio J. Vidal
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-10-13

Post Translational Modifications In Health And Disease written by Cecilio J. Vidal and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-10-13 with Science categories.


Post-translational modifications serve many different purposes in several cellular processes such as gene expression, protein folding and transport to appropriate cell compartment, protein-lipid and protein-protein interactions, enzyme regulation, signal transduction, cell proliferation and differentiation, protein stability, recycling and degradation. Although several-hundred different modifications are known, the significance of many of them remains unknown. The enormous versatility of the modifications which frequently alter the physico-chemical properties of the respective proteins represents an extraordinary challenge in understanding their physiological role. Since essential cellular functions are regulated by protein modifications, an improvement of current understanding of their meaning might allow new avenues to prevent and/or alleviate human and animal diseases.



Translation Mechanisms And Control


Translation Mechanisms And Control
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Author : Michael B. Mathews
language : en
Publisher:
Release Date : 2018-09-30

Translation Mechanisms And Control written by Michael B. Mathews and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-09-30 with Genetic translation categories.


A subject collection from Cold Spring Harbor Perspectives in Biology.



Translational Control In Biology And Medicine


Translational Control In Biology And Medicine
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Author : Michael Mathews
language : en
Publisher: CSHL Press
Release Date : 2007

Translational Control In Biology And Medicine written by Michael Mathews and has been published by CSHL Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Medical categories.


Updated and broadened 3rd edition. Since the last edition was published, the structures of the bacterial and eukaryotic ribosomes have been published, adding substantially to our knowledge of the basic mechanisms of translation. Understanding of how translation is regulated, by both protein and RNA regulators, has also advanced considerable. In addition, the current manifesttion of this volume has a significant focus on the role of translational control in human development and disease.



Translational Control


Translational Control
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Author : Michael B. Mathews
language : en
Publisher:
Release Date : 1986

Translational Control written by Michael B. Mathews and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986 with Science categories.




Translational Control In Biology And Medicine


Translational Control In Biology And Medicine
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Author :
language : en
Publisher:
Release Date : 2007

Translational Control In Biology And Medicine written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with categories.




Transcription And Translation In Health And Disease


Transcription And Translation In Health And Disease
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Author : Manoj Garg
language : en
Publisher: Elsevier
Release Date : 2023-01-30

Transcription And Translation In Health And Disease written by Manoj Garg and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-01-30 with Science categories.


Transcription and Translation in Health and Disease provides a detailed overview of the regulators underlying transcription and translation in relation to a variety of human diseases and disorders. Beginning with an introduction into the current perspectives relating to these processes in human disease, the book expands to focus on specific mechanisms underlying conditions such as arthritis, cancer, neurological disorders, diabetes and cardiovascular disease. This book considers RNA processing and related mechanisms in eukaryotes including RNA splicing, RNA binding proteins, RNA interference, microRNAs, RNA editing, transcription factors, RNAi screening, CRISPR activation, CRISPR-Cas9 interference, and post-translational modifications. It provides a structured and detailed overview of the various regulators underlying molecular processes and their impact on health and disease, equipping readers with the necessary knowledge for further investigation in the areas of treatment and therapeutic intervention. Discusses the role played by transcription and translational regulation in various diseases, including cancer, diabetes, cardiovascular disease and neurological disease Considers a range of post-transcriptional regulators, including RNA-binding proteins, non-coding RNAs, epigenetic modifiers, alternative splicing and telomerase-binding proteins Covers the topic from fundamental knowledge to the latest developments in clinical application Includes a section dedicated to therapeutic applications