Translational Methods For Ptsd Research
DOWNLOAD
Download Translational Methods For Ptsd Research PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Translational Methods For Ptsd Research book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Translational Methods For Ptsd Research
DOWNLOAD
Author : Graziano Pinna
language : en
Publisher: Springer Nature
Release Date : 2023-07-02
Translational Methods For Ptsd Research written by Graziano Pinna and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-07-02 with Medical categories.
This volume explores the latest experimental techniques in animal models of PTSD and humans affected by PTSD. The methods discussed in this book cover topics such as translational research; addressing sex differences; highlighting the state-of-the-art of biomarker discovery in the development and maintenance of PTSD; and looks at new promising agents to enhance fear extinction retention that may help millions of individuals that suffer from this debilitating disorder worldwide. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Authoritative and thorough, Translational Methods for PTSD Research is a valuable resource that will help researchers understand and learn more about this important disorder.
Posttraumatic Stress Disorder
DOWNLOAD
Author : J. Douglas Bremner
language : en
Publisher: John Wiley & Sons
Release Date : 2016-04-18
Posttraumatic Stress Disorder written by J. Douglas Bremner and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-18 with Medical categories.
Posttraumatic Stress Disorder: From Neurobiology to Treatment presents a comprehensive look at this key neuropsychiatric disorder. The text examines the neurobiological basis of post-traumatic stress and how our understanding of the basic elements of the disease have informed and been translated into new and existing treatment options. The book begins with a section on animal models in posttraumatic stress disorder research, which has served as the basis of much of our neurobiological information. Chapters then delve into applications of the clinical neuroscience of posttraumatic stress disorder. The final part of the books explores treatments and how our basic and clinical research is now being converted into treatment. Taking a unique basic science to translational intervention approach, Posttraumatic Stress Disorder: From Neurobiology to Treatment is an invaluable resource for researchers, students and clinicians dealing with this complex disorder.
Translational Study Of Post Traumatic Stress Disorder
DOWNLOAD
Author : David Dopfel
language : en
Publisher:
Release Date : 2021
Translational Study Of Post Traumatic Stress Disorder written by David Dopfel and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021 with categories.
Development of clinical diagnostic criteria has driven progress since the paradigm shift in psychiatric care toward modern medical practice in the mid-20th century. This shift toward a biological understanding of psychiatric disorders led to the discovery of drug-treatment options, but has yet to lead to definition of any clinical biomarkers for psychiatric disorders. Due to advances in genomics, metabolomics, and neuroimaging methods, biomarker discovery has become a major research focus. In clinical studies this has centered around comparing patient population to control populations. However, in the case of post-traumatic stress disorder, comparison of patient populations with healthy controls has been shown to highlight differences in the populations that may be independent of PTSD diagnosis. Twin studies have shown that many factors found in past PTSD studies were also characteristic of the non-PTSD diagnosed healthy twin. This is cause for skepticism toward the results of clinical trials where biomarkers of psychiatric disorders are being studied, as they may not differentiate diagnostic biomarkers from susceptibility biomarkers. Preclinical studies done using psychiatric disorder models will be critical in biomarker discovery due to the complexity of studying psychiatric disorder development and of structuring studies that can delineate different types of biomarkers in humans. This work leveraged an animal model of post-traumatic stress disorder and a multi-modal approach to investigate psychiatric disorder development. We assessed trauma response and outcome through behavioral monitoring of freezing during the trauma itself and PTSD-like behavioral assessment after a prolonged period post-trauma respectively. The effect of trauma on neuroendocrine response was also measured in a subset of animals through corticosterone assay. To investigate neuroimaging biomarkers of susceptibility we measured pre-trauma brain-wide functional connectivity using awake rodent resting state functional magnetic resonance imaging. Through these methods we found that behavioral response during trauma was correlated with both the neuroendocrine response during trauma and the presentation of PTSD-like symptoms post-trauma. The freezing behavior during trauma was also correlated with the functional connectivity measures pre-trauma and revealed a subset of brain circuits that form a network framework of PTSD susceptibility. These results represent the importance of animal model studies of psychiatric disorders in their ability to differentiate biomarkers of susceptibility versus disorder through longitudinal assessment of disorder development.
Optimization Of Research And Clinical Applications For Combat Related Posttraumatic Stress Disorder Ptsd
DOWNLOAD
Author : Seth D. Norrholm
language : en
Publisher:
Release Date : 2010
Optimization Of Research And Clinical Applications For Combat Related Posttraumatic Stress Disorder Ptsd written by Seth D. Norrholm and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Post-traumatic stress disorder categories.
The state of ongoing military conflict in the Middle East and the recent rise in acts of domestic terrorism have created an increasing need for identifying potential vulnerability risk factors and for developing more effective treatment strategies for posttraumatic stress disorder (PTSD). This book reviews the most promising translational research findings that will help shape the direction and form for the optimal clinical applications for combat-related PTSD in the current military climate.
Translational Research In Traumatic Brain Injury
DOWNLOAD
Author : Daniel Laskowitz
language : en
Publisher: CRC Press
Release Date : 2016-04-21
Translational Research In Traumatic Brain Injury written by Daniel Laskowitz and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-21 with Medical categories.
Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the developme
Translational Medicine In Cns Drug Development
DOWNLOAD
Author : George G. Nomikos
language : en
Publisher: Academic Press
Release Date : 2019-06-18
Translational Medicine In Cns Drug Development written by George G. Nomikos and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-18 with Medical categories.
Translational Medicine in CNS Drug Development, Volume 29, is the first book of its kind to offer a comprehensive overview of the latest developments in translational medicine and biomarker techniques. With extensive coverage on all aspects of biomarkers and personalized medicine, and numerous chapters devoted to the best strategies for developing drugs that target specific disorders, this book presents an essential reference for researchers in neuroscience and pharmacology who need the most up-to-date techniques for the successful development of drugs to treat central nervous system disorders. Despite increases in the number of individuals suffering from CNS-related disorders, the development and approval of drugs for their treatment have been hampered by inefficiencies in advancing compounds from preclinical discovery to the clinic. However, in the past decades, game-changing strides have been made in our understanding of the pathophysiology of CNS disorders and the relationship of drug exposure in plasma and CNS to pharmacodynamic measures in both animals and humans. Includes comprehensive coverage of biomarker tools and the role of personalized medicine in CNS drug development Discusses strategies for drug development for a full range of CNS indications, with particular attention to neuropsychiatric and neurocognitive disorders Includes chapters written by international experts from industry and academia
Emotion In Posttraumatic Stress Disorder
DOWNLOAD
Author : Matthew Tull
language : en
Publisher: Academic Press
Release Date : 2020-01-31
Emotion In Posttraumatic Stress Disorder written by Matthew Tull and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-31 with Education categories.
Emotion in Posttraumatic Stress Disorder provides an up-to-date review of the empirical research on the relevance of emotions, such as fear, anxiety, shame, guilt, and disgust to posttraumatic stress disorder (PTSD). It also covers emerging research on the psychophysiology and neurobiological underpinnings of emotion in PTSD, as well as the role of emotion in the behavioral, cognitive, and affective difficulties experienced by individuals with PTSD. It concludes with a review of evidence-based treatment approaches for PTSD and their ability to mitigate emotion dysfunction in PTSD, including prolonged exposure, cognitive processing therapy, and acceptance-based behavioral therapy. Identifies how emotions are central to understanding PTSD. Explore the neurobiology of emotion in PTSD. Discusses emotion-related difficulties in relation to PTSD, such as impulsivity and emotion dysregulation. Provides a review of evidence-based PTSD treatments that focus on emotion.
Basic And Translation Research In Learning And Memory
DOWNLOAD
Author : Adebobola Imeh-Nathaniel
language : en
Publisher: Frontiers Media SA
Release Date : 2023-05-17
Basic And Translation Research In Learning And Memory written by Adebobola Imeh-Nathaniel and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-05-17 with Science categories.
Neurobiology And Physiology Of The Endocannabinoid System
DOWNLOAD
Author : Vinood B. Patel
language : en
Publisher: Elsevier
Release Date : 2023-06-02
Neurobiology And Physiology Of The Endocannabinoid System written by Vinood B. Patel and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-06-02 with Psychology categories.
Neurobiology and Physiology of the Endocannabinoid System offers readers a comprehensive reference on the neurobiology of this system and the use of cannabimimetic compounds to induce neurological changes and confer symptom relief. With sections on both natural and synthetic compounds, the book's broad coverage allows readers to learn about their use with multiple conditions, as well as the working biology of the endocannabinoid system, its receptors and its ligands. This volume provides a platform for research on the effects of this system and its modulation in brain function and neurological dysfunction. Summarizes research on the working neurobiology of the endocannabinoid system Contains chapter abstracts, key facts, a dictionary and a summary Covers both natural cannabinoids and synthetic or exogenous cannabimimetics Includes conditions like headache, anxiety, stress and neuroinflammation Discusses system modulation in the context of pain, traumatic brain injury and obesity
Us National Institute Of Health Handbook Volume 1 Strategic Information And Contacts
DOWNLOAD
Author : IBP USA
language : en
Publisher: Lulu.com
Release Date :
Us National Institute Of Health Handbook Volume 1 Strategic Information And Contacts written by IBP USA and has been published by Lulu.com this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.